LOCUS       NM_001037348            1130 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus aminoacyl tRNA synthetase complex-interacting
            multifunctional protein 2 (Aimp2), mRNA.
ACCESSION   NM_001037348 XM_213710
VERSION     NM_001037348.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1130)
  AUTHORS   Ko,H.S., Lee,Y., Shin,J.H., Karuppagounder,S.S., Gadad,B.S.,
            Koleske,A.J., Pletnikova,O., Troncoso,J.C., Dawson,V.L. and
            Dawson,T.M.
  TITLE     Phosphorylation by the c-Abl protein tyrosine kinase inhibits
            parkin's ubiquitination and protective function
  JOURNAL   Proc Natl Acad Sci U S A 107 (38), 16691-16696 (2010)
   PUBMED   20823226
REFERENCE   2  (bases 1 to 1130)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 1130)
  AUTHORS   Yannay-Cohen,N., Carmi-Levy,I., Kay,G., Yang,C.M., Han,J.M.,
            Kemeny,D.M., Kim,S., Nechushtan,H. and Razin,E.
  TITLE     LysRS serves as a key signaling molecule in the immune response by
            regulating gene expression
  JOURNAL   Mol Cell 34 (5), 603-611 (2009)
   PUBMED   19524539
REFERENCE   4  (bases 1 to 1130)
  AUTHORS   Kaminska,M., Havrylenko,S., Decottignies,P., Le Marechal,P.,
            Negrutskii,B. and Mirande,M.
  TITLE     Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the
            Cytoplasm of Human Cells
  JOURNAL   J Biol Chem 284 (20), 13746-13754 (2009)
   PUBMED   19289464
REFERENCE   5  (bases 1 to 1130)
  AUTHORS   Kaminska,M., Havrylenko,S., Decottignies,P., Gillet,S., Le
            Marechal,P., Negrutskii,B. and Mirande,M.
  TITLE     Dissection of the structural organization of the aminoacyl-tRNA
            synthetase complex
  JOURNAL   J Biol Chem 284 (10), 6053-6060 (2009)
   PUBMED   19131329
REFERENCE   6  (bases 1 to 1130)
  AUTHORS   Kim,M.J., Park,B.J., Kang,Y.S., Kim,H.J., Park,J.H., Kang,J.W.,
            Lee,S.W., Han,J.M., Lee,H.W. and Kim,S.
  TITLE     Downregulation of FUSE-binding protein and c-myc by tRNA synthetase
            cofactor p38 is required for lung cell differentiation
  JOURNAL   Nat Genet 34 (3), 330-336 (2003)
   PUBMED   12819782
REFERENCE   7  (bases 1 to 1130)
  AUTHORS   Kim,J.Y., Kang,Y.S., Lee,J.W., Kim,H.J., Ahn,Y.H., Park,H., Ko,Y.G.
            and Kim,S.
  TITLE     p38 is essential for the assembly and stability of macromolecular
            tRNA synthetase complex: implications for its physiological
            significance
  JOURNAL   Proc Natl Acad Sci U S A 99 (12), 7912-7916 (2002)
   PUBMED   12060739
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC107947.1.
            
            On Nov 25, 2005 this sequence version replaced XM_213710.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107947.1, EV771077.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1130
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12p11"
     gene            1..1130
                     /gene="Aimp2"
                     /gene_synonym="Jtv1"
                     /note="aminoacyl tRNA synthetase complex-interacting
                     multifunctional protein 2"
                     /db_xref="GeneID:288480"
                     /db_xref="RGD:1560787"
     exon            1..172
                     /gene="Aimp2"
                     /gene_synonym="Jtv1"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..1000
                     /gene="Aimp2"
                     /gene_synonym="Jtv1"
                     /note="protein JTV-1; multisynthetase complex auxiliary
                     component p38; multisynthase complex auxiliary component
                     p38; JTV1; rCG42778-like"
                     /codon_start=1
                     /product="aminoacyl tRNA synthase complex-interacting
                     multifunctional protein 2"
                     /protein_id="NP_001032425.1"
                     /db_xref="GeneID:288480"
                     /db_xref="RGD:1560787"
                     /translation="MPMYQVKPYHGGSAPLRVELPTCMYRLPNVHSKTTSPATDAGHV
                     QEPSEPSLRALESRQDDILKRLYELKAAVDGLSKMIHTPDADLDVTNILQADEPTTLT
                     TNALDLNSVLGKDYGALKDIVINANPASPPLSLLVLHRLLCERYRVLSTVHTHSSVKN
                     VPENLLKCFGEQARKQSRHEYQLGFTLIWKNVPKTQMKFSVQTMCPIEGEGNIARFLF
                     SLFGQKHNAVHLTLIDSWVDIAMFQLREGSSKEKAAVFRSMNSALGKSPWLVGNELTV
                     ADVVLWSVLQQTGGSSGAAPTNVQRWLKSCENLAPFSTALQLLK"
     exon            173..379
                     /gene="Aimp2"
                     /gene_synonym="Jtv1"
                     /inference="alignment:Splign:2.1.0"
     exon            380..611
                     /gene="Aimp2"
                     /gene_synonym="Jtv1"
                     /inference="alignment:Splign:2.1.0"
     exon            612..1102
                     /gene="Aimp2"
                     /gene_synonym="Jtv1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgtccctc gcccgctacc ttcctttggt tcccaccatg ccgatgtacc aggtaaagcc
       61 ctatcatgga ggcagcgcac ctctgcgtgt agagcttcca acctgcatgt accggctccc
      121 caacgtgcac agcaagacca ccagccccgc gaccgacgcg ggccacgtgc aggagccatc
      181 tgagccatct ttgcgagccc tcgagtctcg gcaggatgat attttaaagc gtttgtatga
      241 gttgaaggca gcagtcgacg gcctttcaaa gatgattcac accccagatg ccgacttgga
      301 cgtcaccaac atcctgcaag ccgacgagcc cacgacttta actacaaatg cattggactt
      361 gaactccgtg cttggaaagg attatggggc gctgaaagat atcgtgatca acgcaaaccc
      421 agcctccccg ccactgtccc tgcttgtgct acatagacta ctctgtgaac gctacagggt
      481 cctgtccaca gtacacacac attcgtccgt caagaatgta cctgagaatc ttctcaagtg
      541 cttcggggag caggctagaa aacagtcccg ccacgagtat cagctgggct tcactctgat
      601 ttggaagaac gtgcccaaga cacagatgaa gttcagtgta caaacgatgt gccccattga
      661 aggagaaggg aacatcgcac gcttcctgtt ctctctattt ggtcagaagc ataacgctgt
      721 ccacctaacc ctcatcgaca gctgggtgga tatcgccatg tttcagctga gagaagggag
      781 cagtaaggaa aaagcggctg ttttccgctc tatgaactcc gctttgggga aaagcccgtg
      841 gttggttggg aatgagctca ctgtggcaga tgtggtgctg tggtccgtgc tccagcagac
      901 tgggggaagc agtggggcag cgcccaccaa tgtgcagcgg tggcttaagt cctgtgagaa
      961 cctggccccc ttcagcactg ccctccagct ccttaagtga attcgagcag cttgtcttgc
     1021 aggcaggatt caacataatg gtctgttgtc agaaagggac ttgtccaatt gtcaggcatc
     1081 aataaaagca ccatatgatc taaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
