LOCUS       XM_008769802            7910 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus absent in melanoma 2 (Aim2),
            transcript variant X3, mRNA.
ACCESSION   XM_008769802
VERSION     XM_008769802.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051348.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008769802.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008769802.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7910
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7910
                     /gene="Aim2"
                     /note="absent in melanoma 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     ESTs, 4 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 16 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:304987"
                     /db_xref="RGD:1307283"
     CDS             6341..7411
                     /gene="Aim2"
                     /codon_start=1
                     /product="interferon-inducible protein AIM2 isoform X1"
                     /protein_id="XP_008768024.1"
                     /db_xref="GeneID:304987"
                     /db_xref="RGD:1307283"
                     /translation="MESDFREMLLLTGLDHITEEELKRFKYLALTEFNIPRKTLNIAD
                     RTELADQLIQSAGAASAVAKAISIFQKLNYMDIAKALEEKKKEAESKYVTNTKKRGTQ
                     KVENRSQAKNCSVASATCSDKDFKGHSATEVCPQVKPQKKQMVAEQEAIREDLQQDSL
                     VVMVLKAMNPFECETQEGKQKIFHATVATETEFFFVKVLNAQFKDKFIPKRTIQISNY
                     LRHSYFVEVTSSSVVVDVESSHKVCVPNNIMKKAGETPKISKLKTLPCGTIVNGLFKV
                     QKITEQKDRVIYGIHDKRGTMEVLVLGNQSKTKCEEGDKIRLTFFEVSNNRGKIQLKS
                     GPCSIYKVIKAAKPKTKVKSVE"
ORIGIN      
        1 cctcttctat actatagttt cttctcatct tggtcccttc tgacatcaac ataataacca
       61 cagcatcaca acaatcattt ataactacct gcctgaagta ttgaaacaag gttaatatgc
      121 ttttctctcc aatggtcctg tctccttagg gaatttttaa taatacacaa agtaggatat
      181 ttttaattag gtgattaaaa tttcaaatgt ttcttgtcta accttcatta tgctatttta
      241 aaggtagggt tttctactgc aaagcaagca tggaggtctt aaagatttca ggtcacacag
      301 actgtgttgg caaggatggt ttaggtagaa ggtgatctag gtgcttttca gtataggctg
      361 caaagaagaa agaccaaaga ataaaggtgt aggtcagagg gttagaggtt agaagggtat
      421 tttaatttat agctgtaaat gaaggactca gaggagctca ttcatgaatg gaggccttgg
      481 ggccccaaat agccaatgta agacactact tgatctgtag cagaattcaa agggtaggtg
      541 ttggctcaag gaaccaaagc ttgattggtt gcagttgacc cttgccaaaa aacattttcc
      601 attcaggctc catatattcc ccaccttggc aatagcctac gaattcttta gtgtaagagg
      661 aaaacagcag gtagatctga aagtttcttt tctttgaatc cagattaact aaatgaatca
      721 tggtaaattg taggacattt ataccaaagt agccaaattt tccataatta tattaaattc
      781 atacagagga atgaaaatca cttggcagaa ttttcacaga tcagcagtgg gactatgagt
      841 ggtttttata gtatgcttgt ttgactaaaa tttctgattt ttgaagcaat gatttaaatt
      901 gcttttgtaa catgtacaaa ggtaagaaca agcaagctta ataaaataaa tggtaaaaca
      961 gaagaaaact gtatgttttt tggagaattt ctacttttca tttctttttt ttttgctagc
     1021 aaaagcaaca cagaataatc tactgaaaat aaattatagg tacaaagcag acagttaaaa
     1081 acaatcctta actttggaaa attgatttga aaatgtaaac ttgcaaaaat agctaaaaag
     1141 tgattgtgat gggggtgctg ttcaactgtc aagttaccaa caattttaaa acagtaccca
     1201 cactgagaat attgtttctt aaaataattg actatacaca taaatacgta tagtagcggt
     1261 aaacagttgc ttaaaggtat aacaagaaca gctcaagtaa ccatgggccc agcactcagt
     1321 tctagaacaa attagtgcag ggacttctaa aactccatga tgatacccac tcttatccac
     1381 tttctgcctt cctgaaatac acactgagta tcttggactg ttatcacttt gtatcgttca
     1441 acaatatgct gcttttataa tatacattca tatatattat acactactag gtctacagat
     1501 gttgccaatg tcattcatgt tctttgtggt tcatttccat ctgtattgta cagcactctc
     1561 tgcaaatctg acagtctccc ctttctcttt ctacccttac ttgctctcac tgtccttcat
     1621 cttttctctc cctcctatct ttcctctccc ctctgtgggt cctaaccaat cagcatggtt
     1681 gaaagcttcc tccaggaatg ggagttggaa tatgtatatt tttaaaattt aatagaagat
     1741 tttgcattta tttcaagcaa attacatctt tgtgcaccac cagcagtatg atctagatga
     1801 tacatatggg ttggataaat gtctcaatgg gtaaaaattt cttactgggt aatgtgagga
     1861 cctgagatta gaactctaga actcacaaaa ggcaaagata atgtacacct ttaaccttgg
     1921 tgcttgagga gcagacagag gtggtttgga tccctggtcc ttgctggcca tcgactgaaa
     1981 ctataagtgt aagttccagg ataaatgaac aatctctctc tctctctctc tctctctctc
     2041 tctctctctc tctctctctc tctctctctc tctctctctc tctcacacac acacacacac
     2101 acacacatac acacagacca ccccacattg acttccccat acccattcac tcagacccac
     2161 ctaccaatac actcataaat atgcatacac atatacctat aaatacagaa cataacacac
     2221 ctgcacataa atgcacatac atacatgcac acacacacat atgtgcatcc cacagccaca
     2281 tgcatgtatg ttcacataca tacataacac atgtctacat gtatatatgc acaccccaca
     2341 tggatatgac tatacatata cgtgtgcaca cacagacaca agctccttta tatccacatg
     2401 cacatccaca tataactatc acatagacaa acattctcac acatgcacat acacaccatt
     2461 aaaggacaca aaaaccacac acatgcacaa acatatatac caacatatgc acaggaacat
     2521 acacaaagat agtaagagtt ttcatgttat agatgtgagg tagagcttag aaagtatcta
     2581 aacctctttg tatagacact aaaaaacaag gagatataaa attgaaaggc aggacatcta
     2641 agtgttaata tacattaaac tataaccatg acaaagccat gcaatatgaa gcaaacactt
     2701 caaatagcat ataagaggaa acaattcata gattttaatt tacacactgt ttacctcttc
     2761 ctatgcttct ggacatatat ccatgtgcct tctggtatgt ctctacacta cagttttact
     2821 ctttagttaa agtgacaata tttgtggata tgacagaggt taggagtcaa gtatcatgct
     2881 atgttgaatt tctaagacac agatgctgag atttgcctga gggagtcaca ggagcatttg
     2941 taggtgagag aggtaaactg cattgggcag agggagaagc tgaactcaca cattagtagt
     3001 agcagctgca gaagccccct caggtcccct caggcttgga tggctttcag ttgtccagag
     3061 atgaggcacc ctttccagaa gttaacagtt gccttcaagc tgagtacaag cagcagtgtg
     3121 accttgggca aggtgtctcc ctttgcagaa gatgattctg gtacaaaact cagctgtcag
     3181 tagcatgtac tcttagttgg ggcggtgagc aatgggttaa gggattgaag gtcagggtgg
     3241 tgacaatttc cagtgcagtt acaataaaca gttactgaac cacaaccaca cagaataggt
     3301 aagtcagggg tgagcagaaa gtggtttgtg gccatcctag aagacagggt agaaaatatt
     3361 tgaatgattt tgtggtaata tgcttcatgg attcaggaga tatatcttgg agtgtccaat
     3421 ttttttgtgt gtgggctggt atatatttta aagagctttg tgttgtccag agaagaaaat
     3481 aatgaaacag tgacaaagac gaagaacttg ggaaatgcca gaaactgagc agggaagcca
     3541 gggtggttgg aaaggtaagc aagcttagaa gagactttta gtaagacagc tgctttcacc
     3601 tctgtgcttc tgttttcatc attagagctg attccattca ctttgtcacc aggaagtggt
     3661 gtggggtaat gtggtaagat tagaatttgg gctgtggttt ctgccggctc aagttcagga
     3721 atcctttttg tacaatgtgt taatcatata accttaacga acctaagcct ctatttaccc
     3781 attctcaatt ttgatgtaac ataagtgagt tattaatcac ttgaaatgtt gactgtaact
     3841 attgaagtta gaggttcaga gacagtgaca gcccaagcca gaaaaagtta cccagactac
     3901 agaagtcttg tatcatgtcc tgtgtgagaa ctcccaacca gacattttaa ggaagaattt
     3961 tatgtcatct ttaaataaaa gacaaagaaa cgatgatgac acaaagtaaa tatgagaagt
     4021 ggatgcatat gcatgtgtgt gtatgtatgt acatatgtat gcatgcattt ttagctatca
     4081 acaaagagaa aagaaacggt tggtatttgg atattacagc tttattgaca taagagtgag
     4141 gtgttggtta ccaatatgca gaagaaattt aattagagaa tcagggtgat gctcttgata
     4201 tcaggaatca ataaacgata gactgcatta gcttatgaga atcttggtgt attagatacc
     4261 ttcatatttg tgatgttcag gtatgtcata tgattgataa aatatcccgg tctattcaca
     4321 ggaggacaca ggaatcaggt gtcagagaca gagattctat cttatgcaca catacatgca
     4381 tacataaatg catgcatgta tgcatatatg cacacacatg cacacatgca gacacataca
     4441 cacatgcaga cacatacaca catgtgcgtg tgtacacaca tgctcatacc atgttgccgt
     4501 gctttgtcat ggcctgagta tatcccaatg actcggtgct tgtccttgtc tctccgtttc
     4561 ctgctcttct gcccttccgc agcctctgta actgtcagtt ctctctttta tccccagcta
     4621 cattaacttt tccataattt tgtaaatctt atcccacctg acaagcaatg agcaagcaga
     4681 agtagaaagt tactaactgt aaagagaagc gcaacagaag gacctgtctt ttacatacag
     4741 aaatggtgtg atggattctt atcattaaaa gctcattagc aagtgattat tataaatgtt
     4801 gggctgtaaa ctggaaaaaa ccctgttatt atccccatgt atcctgaatt tcagcacagg
     4861 ggtggtcctt gcatatagac ttccattgca gaatcagaaa tcaactgact cctcttacag
     4921 tccgcatgtc cttacatcac ctctgactta tccttttcac tagtgttctg agtatgaatc
     4981 acactaaaca gacatggtaa gcagtcatga tgagttgggc atgggatggt cttatagaga
     5041 ttagtaaaac tcacacacaa gtaacatttg taggctgaca tctcagtata ttacattctc
     5101 tttgctcatt gttatttttg aaacatggac ttatctagcc caagttgtcc ttgaagttcc
     5161 tttgtagcca gagatggctt tgaaatgatc ttgccacccc caccctttaa gtgcagcatc
     5221 ctggctggct tgatttttac attgtttatt aacaatattt gaagatgtca tatgctccta
     5281 tagcttgcaa ttttatgaaa atagaaacaa cacaaaagaa tttcatgata ctagtaatgg
     5341 tgcacggcat ttgctggatg ttttacattt ttcagttaac atttcttagt attaactata
     5401 taaactcaat gttcataatg acttcccccc ataggtacac tcaggtactc tcatggagta
     5461 ggtacttcag aaggccacga gacttaagct cacccaagtc gatgtgtatt ttcatttgta
     5521 tgttagggta gcagatctca cgaatctgtg tctaatgcaa ctataatagg atgaccaggg
     5581 aatcctgact ttgggcttgg aggatttaag aatgatttta gaagaagaga attgtaaaga
     5641 cagatctagc tatggtaagt aattgatcaa atagaggggg atggaaagag tagcaagatt
     5701 tttctcaagg cggcaggact cagtataggg gattgaggga tgtggaggaa ggcctgacca
     5761 ctgacctgag actactggac aaattgtccc tcatgcaggg acaactcaca ccagaaacaa
     5821 ggcctgtgtg caggcagaag gtaaggggaa tcttctacag ggtagcaaaa ctgtctgacc
     5881 ctgcagtttc agaagcttag agctttctcg aaggccgtta tttctgcttt gtccctcttt
     5941 ctgttcatct ttttcaggag agtatggccg agcatacgtc aagtaaccta gactagaagt
     6001 caggaaatga ggggtgaaaa tcataggaaa atgaggaaat gaccaactat atgtttccta
     6061 aatctgagga gagcttttga gatctgaaac cttccactct ctggctttac tgagttatat
     6121 tggcatagat aactggtatc attgcacatt ctgtgaataa tacaaaggca gttggcaaaa
     6181 gagagagcag agggcttgga ttcagaagac ttgaggtcag gccatctagt catcctttat
     6241 aagctgtgtg gcatcaagta agtgattctg cctcgaatcc caatttaacc tacaactgct
     6301 acggagctgg tgttttccag gctgatcctg agtctgggag atggagagtg actttcggga
     6361 aatgctgttg ttgaccggcc tggaccacat cacggaggag gaactgaaac ggttcaagta
     6421 cttggccctg actgagttta acattcccag gaagacactg aacattgcag acaggacgga
     6481 gttagctgac caactaattc aaagtgcagg agcagcatct gcggtggcga aagccattag
     6541 tatttttcag aagttgaatt atatggatat tgcaaaggct cttgaagaga aaaagaaaga
     6601 agctgaaagt aaatatgtga caaatacaaa gaagagagga acacagaaag tagaaaatag
     6661 aagtcaagct aaaaactgtt ctgttgcttc tgccacctgc agtgacaaag acttcaaggg
     6721 acactctgct acagaagtct gtcctcaagt taagcctcag aagaaacaga tggtggcaga
     6781 acaggaagcc atcagagaag atttacagca agattcacta gtagtcatgg tgctgaaagc
     6841 tatgaatccc tttgagtgtg agacccagga aggaaaacaa aagatattcc atgccacagt
     6901 ggccacagag acagaatttt tctttgtaaa agttttaaat gcacagttta aagataaatt
     6961 tattccaaag agaacaattc aaatatcaaa ttatctccgt cacagttact ttgtggaggt
     7021 caccagttcc tcagttgtgg ttgatgttga atctagccac aaagtctgcg ttcctaataa
     7081 cattatgaag aaagctggag aaactcctaa gattagtaaa ctgaaaactc tgccgtgcgg
     7141 gacaattgtg aatggcttat ttaaagtcca gaagataaca gagcaaaaag atagagtaat
     7201 atatggcata catgacaaaa gagggaccat ggaggtgttg gtgcttggaa accagagcaa
     7261 aacaaaatgc gaggaaggag acaagattag actcactttc tttgaggtgt caaacaatag
     7321 agggaaaatt cagttgaaat ctggaccctg tagcatctat aaggttatta aggctgcaaa
     7381 gcccaaaact aaggtgaaaa gtgtggagtg aagtcaactc atctcaaaag cactgttctg
     7441 aagaatccta attctgcttc ttgaaccaga cttaattaac tacctgagga tagcagttta
     7501 cagccgcata ttcctattat attagtaaga aaaggacaaa cacactcaca cacaaaaaaa
     7561 cccaactgaa aatgtattat taattaatta ttattaatta aattattgct ttgtctaagg
     7621 gttgggctat tattcttctc tacaaagaaa ttgagggtat aagtatggca gaattggaga
     7681 tgtgacagct atggctggta tgagagaagc ctgcggttga tagagaagaa ggttggtgat
     7741 atatcttttt taattttaat ttttttaatt ttctttcggg gaggaggtta caagggtgga
     7801 ggttggatat gggaggacta agacatgagt gagatgatgt taaaaaaaag gaaagattgt
     7861 tgaaaaataa ataaacatga ttttattcag aattcagaaa gttacaaaaa
//
