LOCUS       NM_001106100            4485 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus ATP/GTP binding carboxypeptidase 1 (Agtpbp1),
            mRNA.
ACCESSION   NM_001106100 XM_001061502 XM_214420
VERSION     NM_001106100.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4485)
  AUTHORS   Shashi,V., Magiera,M.M., Klein,D., Zaki,M., Schoch,K.,
            Rudnik-Schoneborn,S., Norman,A., Lopes Abath Neto,O., Dusl,M.,
            Yuan,X., Bartesaghi,L., De Marco,P., Alfares,A.A., Marom,R.,
            Arold,S.T., Guzman-Vega,F.J., Pena,L.D., Smith,E.C., Steinlin,M.,
            Babiker,M.O., Mohassel,P., Foley,A.R., Donkervoort,S., Kaur,R.,
            Ghosh,P.S., Stanley,V., Musaev,D., Nava,C., Mignot,C., Keren,B.,
            Scala,M., Tassano,E., Picco,P., Doneda,P., Fiorillo,C., Issa,M.Y.,
            Alassiri,A., Alahmad,A., Gerard,A., Liu,P., Yang,Y.,
            Ertl-Wagner,B., Kranz,P.G., Wentzensen,I.M., Stucka,R., Stong,N.,
            Allen,A.S., Goldstein,D.B., Schoser,B., Rosler,K.M., Alfadhel,M.,
            Capra,V., Chrast,R., Strom,T.M., Kamsteeg,E.J., Bonnemann,C.G.,
            Gleeson,J.G., Martini,R., Janke,C. and Senderek,J.
  CONSRTM   Undiagnosed Diseases Network
  TITLE     Loss of tubulin deglutamylase CCP1 causes infantile-onset
            neurodegeneration
  JOURNAL   EMBO J 37 (23) (2018)
   PUBMED   30420557
REFERENCE   2  (bases 1 to 4485)
  AUTHORS   Rodriguez de la Vega Otazo,M., Lorenzo,J., Tort,O., Aviles,F.X. and
            Bautista,J.M.
  TITLE     Functional segregation and emerging role of cilia-related cytosolic
            carboxypeptidases (CCPs)
  JOURNAL   FASEB J 27 (2), 424-431 (2013)
   PUBMED   23085998
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474032.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_214420.4, XM_001061502.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..4485
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..4485
                     /gene="Agtpbp1"
                     /note="ATP/GTP binding carboxypeptidase 1"
                     /db_xref="GeneID:290986"
                     /db_xref="RGD:1306307"
     exon            1..93
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            94..295
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            296..360
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             329..3988
                     /gene="Agtpbp1"
                     /EC_number="3.4.17.24"
                     /note="ATP/GTP binding protein 1"
                     /codon_start=1
                     /product="cytosolic carboxypeptidase 1"
                     /protein_id="NP_001099570.1"
                     /db_xref="GeneID:290986"
                     /db_xref="RGD:1306307"
                     /translation="MSKLKVVGEKSLTNSSRVVGLLAQLEKINTDSTESDTARHVTSK
                     ILHLAQSQEKTRREMTTKGSTGMEVLLSTLENTKDLQTVLNILSILIELVSSGGGRRA
                     SFLVAKGGSQILLQLLMNASKDSPPHEEVMVQTHSILAKIGPKDKKFGVKARVNGALN
                     ITLNLVKQHFQNYRLVLPCLQLLRVYSTNSVNSVSLGKNGVVELMFKIIGPFSKKNSG
                     LMKVALDTLAALLKSKTNARRAVDRGYVQVLLTIYVDWHRHDNRHRNMLIRKGILQSL
                     KSVTNIKLGRKAFIDANGMRILYNTSQECLAVRTLDPLVNTSSLIMRKCFPKNRLPLP
                     TIKSSFHFQLPIIPVTGPVAQLYNLPPEVDDVVDESDDNDDIDLEAENEVENEDDLDQ
                     SFKNDDIETDINKLRPQQVPGRTIEELKMYEHLFPELVDDFQDYELIAKEPKPFVFEG
                     KVRGPIVVPTAGEEVPGNPGNVRKGAAVKEKASPKGEEVKEDAKGHDKTPPWQLGGQN
                     RAAASAHSSNNDLVKALDRITLQSTPSQVAAGLTAGMRKDYGLPLTVLSCTKACPHVA
                     KCTSALFEGRTVHLGKLCCTGVETEDDEDFESHSSAEQVSSVEASDGPPTLHDPDLYI
                     EIVKNTKSVPEYSEVAYPDYFGHIPPPFKEPILERPYGVQRTKIAQDIERLIHQNDII
                     DRVVYDLDNPNYTTPEEGDILKFNSKFESGNLRKVIQIRKSEYDLILNSDINSNHYHQ
                     WFYFEVSGMRPGVAYRFNIINCEKSNSQFNYGMQPLMYSVQEALNARPWWIRMGTDIC
                     YYKNHFSRSSVAAGGQKGKSYYTITFTVVFPHKDDVCYFAYHYPYTYSTLQMHLQKLE
                     SAHNPQQIYFRKDVLCETLSGNSCPLVTITAMPESSYYEHICQFRTRPYIFLSARVHP
                     GETNASWVMKGTLEYLMSNSPTAQSLREAYIFKIVPMLNPDGVINGNHRCSLSGEDLN
                     RQWQSPNPELHPTIYHAKGLLQYLAAVKRLPLVYCDYHGHSRKKNVFMYGCSIKETVW
                     HTHDNAASCDVVEDMGYRTLPKILSHIAPAFCMSSCSFVVEKSKESTARVVVWREIGV
                     QRSYTMESTLCGCDQGRYKGLQIGTRELEEMGAKFCVGLLRLKRLTSPLEYNLPSNLL
                     DFENDLIESSCKVTSPTTYVLDEDEPRFLEEVDYSAESNDELEVELAENTGDYEPSAQ
                     DEALSDSEVSRTHPI"
     exon            361..485
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            486..553
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            554..617
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            618..764
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            765..896
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            897..990
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1028
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1237
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1415
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1416..1513
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1630
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..2322
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2323..2406
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2407..2493
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2494..2642
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2643..2730
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2731..2875
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2876..3029
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            3030..3210
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            3211..3340
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            3341..3472
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            3473..3649
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            3650..3810
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            3811..4485
                     /gene="Agtpbp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtgtggcaa aggagtggga ttgcagaaag catcatggaa tcgttctacc caagacagaa
       61 gtaacaagac gttatggcgg tgagaagaaa aggtgtgttt tcgtgtggaa atacacgtct
      121 accagtttgg cgctactatg taatcagtgg tcaccttgtc gtggaaagct gtggttggct
      181 tgagaattaa tgaggcatag cagcactgtc tcagaagaaa tcgaagtact gattgtagga
      241 gcagcctttc ataggagtga taaaaccatc acgaaaaaac aacttaaggg agaagattat
      301 ctgcaatgct ggaatgaagt aactcaagat gagcaagcta aaagtggtag gagagaaaag
      361 ccttaccaat agttctcggg ttgtggggct cttggctcag ctggagaaga tcaatacgga
      421 ttccacagag tcagacactg ccagacatgt cacatccaaa attcttcatt tggctcaaag
      481 tcaagaaaaa acaaggaggg aaatgacaac caaaggttct acaggcatgg aagttctgtt
      541 gtcaacattg gagaacacga aagatcttca gactgtactt aatatcctga gcattctcat
      601 cgagctggtg tcctccggtg gaggccgaag agcgagtttc ttagttgcca aaggtggttc
      661 acagattctg ttgcaactgc tcatgaacgc cagcaaagac tctcccccac acgaggaggt
      721 gatggtgcag actcactcca ttcttgccaa gattggacca aaagataaaa aatttggagt
      781 gaaagccaga gtaaatgggg ccctgaatat aactctgaac ctggtcaagc agcactttca
      841 gaactaccgc ctggttctgc cttgtcttca gctgttacga gtgtattcta ccaactctgt
      901 gaactcagta tctttaggta agaatggagt tgtggagctg atgtttaaga tcatcggacc
      961 attcagtaag aagaattcgg gtctcatgaa ggttgcttta gacactcttg ctgcattgct
     1021 aaaatcaaag acaaatgcca ggcgtgccgt agacagaggc tatgttcaag tgcttttaac
     1081 catttatgta gattggcatc gacacgataa ccggcacaga aacatgctca ttcggaaggg
     1141 gattctacag agcttaaaaa gtgtcacgaa catcaaattg ggaagaaaag catttattga
     1201 tgcaaatggg atgagaattc tgtataacac ctcacaagag tgcttggcgg tcaggactct
     1261 ggaccctctt gtcaacacat ccagtctgat aatgaggaaa tgtttcccca aaaaccgcct
     1321 tccactcccc accattaaaa gttctttcca cttccagttg ccaattatcc ctgtgactgg
     1381 acctgtggcc cagctctaca acctgccgcc cgaagtggac gacgtggtgg acgagagtga
     1441 cgacaacgat gacattgatt tagaagctga aaatgaagtc gagaatgaag atgacctaga
     1501 tcaaagtttt aagaatgatg atattgaaac agatattaat aaattaagac cccagcaagt
     1561 accaggacga acaatagaag aactaaaaat gtatgagcac cttttccctg agcttgttga
     1621 tgattttcag gactatgaat taatcgctaa agaacccaaa ccttttgtgt ttgaggggaa
     1681 agttcggggc ccgattgtag ttcccacagc tggagaggaa gtgcctggga atccaggtaa
     1741 cgtaaggaaa ggagctgcag tgaaggagaa agcgagtcct aaaggagagg aagtcaagga
     1801 agatgccaag ggccatgaca aaacaccgcc gtggcagctg ggtggccaga acagagcggc
     1861 cgcttcagcc cacagctcca acaacgatct tgtgaaggcc ttagaccgaa tcacactgca
     1921 gagtacccct tcacaagtag ccgcgggctt gactgcagga atgaggaagg actacggcct
     1981 ccctctcact gtcctctcat gcacgaaagc gtgtcctcac gtggctaagt gcacaagtgc
     2041 ccttttcgaa gggcggacag tacatcttgg taaactgtgt tgtactggag ttgaaacgga
     2101 agatgatgaa gactttgagt cccactcatc agcagagcag gtctcctctg ttgaagcctc
     2161 tgatggacca ccaacactgc atgacccaga cctctacatc gagattgtga aaaatacaaa
     2221 gtctgttccc gagtactcag aggtggccta tcctgattat tttggacaca ttccacctcc
     2281 cttcaaagag cctattttag aaaggcctta tggtgtacaa aggacaaaaa ttgcccaaga
     2341 tatcgagagg ctgatacacc agaatgatat cattgaccgg gtggtgtatg acttagataa
     2401 ccctaactat accactccag aagaaggaga tattttgaag tttaactcaa aatttgaatc
     2461 tgggaatctg cgcaaagtaa ttcaaattag aaaaagcgag tatgacctca ttctgaactc
     2521 tgacataaac agtaaccatt accatcagtg gttctacttt gaagtcagtg ggatgcggcc
     2581 gggtgtggca tacaggttca acatcatcaa ctgtgagaag tccaacagcc agtttaacta
     2641 cggtatgcag ccacttatgt attcagttca ggaagcacta aatgccaggc cgtggtggat
     2701 ccgtatgggt actgacattt gttactacaa aaatcacttc tcgagaagtt ccgtggctgc
     2761 gggtggacag aaggggaagt cctactacac gatcaccttc accgtggtct tcccgcataa
     2821 agatgacgtg tgctactttg cctatcacta cccatacaca tactctactc tgcagatgca
     2881 tcttcaaaaa ttggagtcag cgcacaatcc tcagcaaatc tactttcgaa aagatgtgtt
     2941 gtgtgagacc ttgtctggga acagctgtcc tttggtgacc ataacagcaa tgccagagtc
     3001 cagttactat gagcatatct gtcaattcag aactcgccct tacattttct tgtctgctcg
     3061 ggtgcatcct ggagaaacca atgcaagctg ggtcatgaaa ggaacgctgg agtacctcat
     3121 gagcaatagc ccgaccgccc agagcttgcg ggaggcttac atttttaaaa ttgttcccat
     3181 gctcaatcca gacggtgtca tcaatggaaa tcaccgctgc tccttaagtg gagaggattt
     3241 gaacagacag tggcaaagtc caaacccaga gttacacccc acgatttacc atgcgaaggg
     3301 gctactccag tacctggctg cagtgaagcg cttacctctg gtttactgtg attaccatgg
     3361 ccactctcgg aaaaagaatg tgttcatgta tggctgcagc atcaaagaga cagtgtggca
     3421 cacccatgac aacgcggcct cctgcgatgt tgtggaagac atgggataca ggactttgcc
     3481 taagatcctg agccacatcg ctccggcctt ctgcatgagc agctgtagct ttgtggtgga
     3541 aaaatccaaa gagtccacag ctcgggttgt tgtgtggcgg gaaattggag ttcaaaggag
     3601 ctataccatg gagagtactt tatgtggctg cgatcagggt agatacaagg gtttacagat
     3661 tgggactcga gaactggaag aaatgggagc aaaattttgt gttggtttat tgcgtttgaa
     3721 aagactgact tctccattgg agtacaatct accctccaac ctgcttgact ttgaaaatga
     3781 cttaattgaa tcaagctgta aagtaactag ccccactact tacgttttgg atgaagatga
     3841 acctcggttc cttgaagaag ttgattacag tgcagaaagc aatgacgagt tagaggttga
     3901 attagcggag aatacaggcg attatgagcc ttctgcccaa gacgaagccc tttccgactc
     3961 tgaggtatca agaacacacc ctatttgaac tttcttccac ctttgttaat tgccaagaag
     4021 aaatgaaatg tcttggtttt cgttgcacag gaagtatgag agggacaagc attcagacag
     4081 ctgactcaag acgaaaagga ccttgggcct gtttggtttc aagacaataa atatattatt
     4141 aattgatatt attggcattt gttttatttt agatattcaa tgtactttat ataacattga
     4201 attatcagat gatagaagta tcattgcatg aattttatct cctgtggcac ctgcatcaag
     4261 cagacaaact cagtgtgtcc gagtaaaaat ctaaattata tggagtgaaa atcgttctct
     4321 acatggattt ctccgaatgt gtttgtgtgg aggtggggag atactcaagc taactgctct
     4381 tcagaagcat gtgaactgtg tatggtggct gaactaaccc aaaatttgcc tcgaatccat
     4441 cccattctac atttatcaag ttaaataaaa ctgtatcaga ctctg
//
