LOCUS       NM_053350               2144 bp    mRNA    linear   ROD 04-DEC-2024
DEFINITION  Rattus norvegicus alkylglycerone phosphate synthase (Agps), mRNA.
ACCESSION   NM_053350 XM_575153
VERSION     NM_053350.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2144)
  AUTHORS   Bharti,P., Schliebs,W., Schievelbusch,T., Neuhaus,A., David,C.,
            Kock,K., Herrmann,C., Meyer,H.E., Wiese,S., Warscheid,B., Theiss,C.
            and Erdmann,R.
  TITLE     PEX14 is required for microtubule-based peroxisome motility in
            human cells
  JOURNAL   J Cell Sci 124 (Pt 10), 1759-1768 (2011)
   PUBMED   21525035
REFERENCE   2  (bases 1 to 2144)
  AUTHORS   Zhao,X., Leon,I.R., Bak,S., Mogensen,M., Wrzesinski,K., Hojlund,K.
            and Jensen,O.N.
  TITLE     Phosphoproteome analysis of functional mitochondria isolated from
            resting human muscle reveals extensive phosphorylation of inner
            membrane protein complexes and enzymes
  JOURNAL   Mol Cell Proteomics 10 (1), M110.000299 (2011)
   PUBMED   20833797
REFERENCE   3  (bases 1 to 2144)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 2144)
  AUTHORS   Kikuchi,M., Hatano,N., Yokota,S., Shimozawa,N., Imanaka,T. and
            Taniguchi,H.
  TITLE     Proteomic analysis of rat liver peroxisome: presence of
            peroxisome-specific isozyme of Lon protease
  JOURNAL   J Biol Chem 279 (1), 421-428 (2004)
   PUBMED   14561759
REFERENCE   5  (bases 1 to 2144)
  AUTHORS   Roth,A.D., Leisewitz,A.V., Jung,J.E., Cassina,P., Barbeito,L.,
            Inestrosa,N.C. and Bronfman,M.
  TITLE     PPAR gamma activators induce growth arrest and process extension in
            B12 oligodendrocyte-like cells and terminal differentiation of
            cultured oligodendrocytes
  JOURNAL   J Neurosci Res 72 (4), 425-435 (2003)
   PUBMED   12704804
REFERENCE   6  (bases 1 to 2144)
  AUTHORS   de Vet,E.C., Ijlst,L., Oostheim,W., Wanders,R.J. and van den
            Bosch,H.
  TITLE     Alkyl-dihydroxyacetonephosphate synthase. Fate in peroxisome
            biogenesis disorders and identification of the point mutation
            underlying a single enzyme deficiency
  JOURNAL   J Biol Chem 273 (17), 10296-10301 (1998)
   PUBMED   9553082
REFERENCE   7  (bases 1 to 2144)
  AUTHORS   Zomer,A.W., de Weerd,W.F., Langeveld,J. and van den Bosch,H.
  TITLE     Ether lipid synthesis: purification and identification of alkyl
            dihydroxyacetone phosphate synthase from guinea-pig liver
  JOURNAL   Biochim Biophys Acta 1170 (2), 189-196 (1993)
   PUBMED   8399344
REFERENCE   8  (bases 1 to 2144)
  AUTHORS   Gunawan,J., Rabert,U., Volkl,A. and Debuch,H.
  TITLE     Kinetic studies of alkyl-dihydroxyacetone-phosphate
            (alkyl-glycerone-phosphate) synthase in peroxisomes of rat liver
  JOURNAL   Biol Chem Hoppe Seyler 371 (4), 339-344 (1990)
   PUBMED   2340111
REFERENCE   9  (bases 1 to 2144)
  AUTHORS   Singh,H., Usher,S. and Poulos,A.
  TITLE     Dihydroxyacetone phosphate acyltransferase and
            alkyldihydroxyacetone phosphate synthase activities in rat liver
            subcellular fractions and human skin fibroblasts
  JOURNAL   Arch Biochem Biophys 268 (2), 676-686 (1989)
   PUBMED   2464339
REFERENCE   10 (bases 1 to 2144)
  AUTHORS   Lee,T.C., Fitzgerald,V., Stephens,N. and Snyder,F.
  TITLE     Activities of enzymes involved in the metabolism of ether-linked
            lipids in normal and neoplastic tissues of rat
  JOURNAL   Biochim Biophys Acta 619 (2), 420-423 (1980)
   PUBMED   7407223
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BF524961.1, AF121052.1 and BM389725.1.
            
            On May 2, 2010 this sequence version replaced NM_053350.1.
            
            Sequence Note: This RefSeq record was created from mixed strain
            transcript data because no single transcript from the same strain
            was available for the full length of the gene. The extent of this
            transcript is supported by transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF121052.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                BF524961.1         7-101
            96-1969             AF121052.1         1-1874
            1970-2144           BM389725.1         1-175               c
FEATURES             Location/Qualifiers
     source          1..2144
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q23"
     gene            1..2144
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /note="alkylglycerone phosphate synthase"
                     /db_xref="GeneID:84114"
                     /db_xref="RGD:620364"
     exon            1..313
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..2030
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /EC_number="2.5.1.26"
                     /note="alkyl-DHAP synthase; alkyldihydroxyacetone
                     phosphate synthase; alkyl-dihydroxyacetonephosphate
                     synthase"
                     /codon_start=1
                     /product="alkyldihydroxyacetonephosphate synthase,
                     peroxisomal"
                     /protein_id="NP_445802.2"
                     /db_xref="GeneID:84114"
                     /db_xref="RGD:620364"
                     /translation="MVARGAALSDLSPAPSGLGRQHKAEAMAEAAGEAGASERDPDAV
                     RARRRLRVLSGHLLGRPQEAPSTNECKARRAASAAGASPAASPAAPESGTIPKKRQEL
                     MKWNGWGYNDSKFLLNKKGQVELTGKRYPLSGLALPTLKDWIQNTLGVNLEHKTTSKP
                     SINPSEAPPSIVNEDFLQELKEAHISYSQDADDRVFRAHGHCLHEIFLLREGMFERIP
                     DIVVWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMN
                     RILWVDENNLTAHVEAGITGQDLERQLKESGYCTGHEPDSLEFSIVGGWISTRASGMK
                     KNVYGNIEDLVVHMKMVTPRGVIEKSSQGPRMSTGPDIHHFIMGSEGTLGVITEATIK
                     IRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSS
                     IFTSFLDGFKKFYITKFKGFDPNQISVATLLFEGDREKVLQHEKQVYDIAAKFGGLAA
                     GEDNGQRGYLLTYVIAYMRDLGLEYYVVGESFETSAPWDRVIDLCRNVKERIRRECKE
                     RGVQFAPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAARDEILANGGS
                     LSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPSNIFGNRNLL"
     exon            314..403
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            404..494
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            495..615
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            616..690
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            691..762
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            763..842
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            843..923
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1049
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1158
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1286
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1338
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1415
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1416..1528
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1598
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1599..1660
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1661..1750
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1751..1850
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..1908
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
     exon            1909..2127
                     /gene="Agps"
                     /gene_synonym="Adap-s; Adps; Ads"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggatgcgct gcagcgaatg gtcgcgcggg gcgccgctct gagtgacctt tcacccgcgc
       61 ccagcggcct cgggcggcag cacaaggcgg aagccatggc ggaggcggcg ggagaggcgg
      121 gcgcgagcga gcgggaccca gacgcggtcc gcgcgcgtcg gcggctgcgg gttctgtcgg
      181 gccatctgct gggccggccc caggaggctc cgagtaccaa tgagtgcaaa gcgcggagag
      241 ccgcgtcggc ggccggggcg tcgcccgctg cttctcccgc cgcgccggag tcgggcacca
      301 tccccaagaa gcggcaagaa cttatgaaat ggaatggatg gggctataat gattccaagt
      361 tcttactgaa taagaagggc caggttgagc tgactgggaa aaggtaccct cttagtggct
      421 tggctttacc aactttgaaa gactggatcc aaaacaccct tggagtaaat ctggagcata
      481 aaactacctc taaaccatcc ataaatccta gtgaagcacc tccttctatt gtgaatgaag
      541 atttccttca ggaacttaaa gaagctcata tttcctactc acaagacgca gatgatcgtg
      601 tgtttagagc tcacggtcat tgtcttcatg agatattttt gctcagagaa gggatgtttg
      661 agcggattcc tgatatagtt gtatggccaa catgtcatga tgatgtagtt aagattgtga
      721 atctagcgtg caaatataac ctttgtatca taccaattgg tgggggaacg agtgtatcct
      781 atggcctgat gtgccctgca gatgagacaa gaacaataat ttctttggat acttcacaaa
      841 tgaaccggat tctctgggtt gatgagaaca atctgacagc tcacgtagag gctgggataa
      901 caggacaaga tttggaaaga cagcttaaag aaagtggtta ttgtacaggt catgaaccgg
      961 actccctaga attcagcatc gtgggaggat ggatatctac tcgagcatca ggcatgaaga
     1021 agaatgtcta cggcaatatt gaggacctgg tggttcacat gaaaatggta acacctagag
     1081 gtgtaataga gaaaagctcc caaggccctc ggatgtcaac ggggcctgat atccatcact
     1141 tcatcatggg ctctgaagga actcttggtg taataacaga agctacaata aaaatcagac
     1201 caactcctga ataccaaaag tatggttcag tggctttccc taattttgaa caaggtgtag
     1261 cctgtttaag agaaattgca aagcagagat gtgctcctgc atctatccgc ctcatggaca
     1321 accagcagtt tcagtttggg catgctctta aacctcaggt ctcctctatt tttacgtcat
     1381 ttttggatgg attcaaaaag ttttatatta caaagtttaa aggatttgat ccaaatcaaa
     1441 taagcgtagc cacattactg ttcgagggag accgtgagaa ggttcttcag catgaaaaac
     1501 aagtgtatga catcgcagca aaatttggtg gtctggctgc tggagaagat aacgggcaga
     1561 ggggttattt gctgacttat gtcattgcat acatgcgtga tttgggtttg gaatactatg
     1621 tagtaggaga atcttttgag acttctgctc cttgggacag ggttatagat ctgtgtagaa
     1681 atgtaaaaga aaggataaga agggaatgca aagaaagggg agttcagttt gcgcctcttt
     1741 ctacgtgcag ggtgacgcag acttacgatg caggtgcatg tatctacttc tattttgcct
     1801 ttaactacag gggaattagt gacccactga ctgtgtttga acagactgag gcagctgcta
     1861 gagatgaaat ccttgccaat ggagggagcc tgtcacatca ccatggagtg ggcaagttac
     1921 gaaagcagtg gctaaaggag agcatctctg atgtcggctt tgggatgcta aagtctgtca
     1981 aagactatgt ggaccccagt aacatctttg gaaacagaaa ccttttataa ctccattaat
     2041 atcattatgg aaaatgttac cttttaaaaa gtcatcagct atggttatac cagtaatcga
     2101 atatatcatg ggactgtatt tcagctaaaa aaaaaaaaaa aaaa
//
