LOCUS       NM_001108564            7567 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus amylo-alpha-1,6-glucosidase and
            4-alpha-glucanotransferase (Agl), mRNA.
ACCESSION   NM_001108564 XM_001073642 XM_342331
VERSION     NM_001108564.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7567)
  AUTHORS   Cheng,A., Zhang,M., Gentry,M.S., Worby,C.A., Dixon,J.E. and
            Saltiel,A.R.
  TITLE     A role for AGL ubiquitination in the glycogen storage disorders of
            Lafora and Cori's disease
  JOURNAL   Genes Dev 21 (19), 2399-2409 (2007)
   PUBMED   17908927
REFERENCE   2  (bases 1 to 7567)
  AUTHORS   Lucchiari,S., Pagliarani,S., Salani,S., Filocamo,M., Di Rocco,M.,
            Melis,D., Rodolico,C., Musumeci,O., Toscano,A., Bresolin,N. and
            Comi,G.P.
  TITLE     Hepatic and neuromuscular forms of glycogenosis type III: nine
            mutations in AGL
  JOURNAL   Hum Mutat 27 (6), 600-601 (2006)
   PUBMED   16705713
REFERENCE   3  (bases 1 to 7567)
  AUTHORS   Lees,S.J., Chen,Y.T. and Williams,J.H.
  TITLE     Glycogen debranching enzyme is associated with rat skeletal muscle
            sarcoplasmic reticulum
  JOURNAL   Acta Physiol Scand 181 (2), 239-245 (2004)
   PUBMED   15180797
REFERENCE   4  (bases 1 to 7567)
  AUTHORS   Becker,K.G., Barnes,K.C., Bright,T.J. and Wang,S.A.
  TITLE     The genetic association database
  JOURNAL   Nat Genet 36 (5), 431-432 (2004)
   PUBMED   15118671
REFERENCE   5  (bases 1 to 7567)
  AUTHORS   Schliselfeld,L.H. and Danon,M.J.
  TITLE     Inverse relationship of skeletal muscle glycogen from wild-type and
            genetically modified mice to their phosphorylase a activity
  JOURNAL   Biochem Biophys Res Commun 290 (2), 874-877 (2002)
   PUBMED   11785984
REFERENCE   6  (bases 1 to 7567)
  AUTHORS   Popova,I.A., Presnova,V.N. and Lavrenova,T.P.
  TITLE     [Effect of biogenic amines on glycogen degradation in isolated rat
            hepatocytes]
  JOURNAL   Vopr Med Khim 38 (2), 30-33 (1992)
   PUBMED   1413626
REFERENCE   7  (bases 1 to 7567)
  AUTHORS   Chen,Y.T., He,J.K., Ding,J.H. and Brown,B.I.
  TITLE     Glycogen debranching enzyme: purification, antibody
            characterization, and immunoblot analyses of type III glycogen
            storage disease
  JOURNAL   Am J Hum Genet 41 (6), 1002-1015 (1987)
   PUBMED   2961257
REFERENCE   8  (bases 1 to 7567)
  AUTHORS   Satoh,K. and Sato,K.
  TITLE     Glycogen-binding protein components of rat tissues
  JOURNAL   Biochem Biophys Res Commun 96 (1), 28-33 (1980)
   PUBMED   6449198
REFERENCE   9  (bases 1 to 7567)
  AUTHORS   Vaillant,R., Bourgeois-Victor,P. and Fairand,A.
  TITLE     [Development and control of liver amylo-1,6-glucosidase activity in
            the fetal rat]
  JOURNAL   Can J Biochem 57 (10), 1245-1249 (1979)
   PUBMED   120213
REFERENCE   10 (bases 1 to 7567)
  AUTHORS   Mannan,A., Noujaim,A.A., Wiebe,L.I., Secord,D.C. and
            Silverberg,D.S.
  TITLE     Carbohydrate metabolism in the chronically uremic rat
  JOURNAL   Clin Biochem 8 (3), 194-198 (1975)
   PUBMED   807434
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473952.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_342331.3, XM_001073642.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..7567
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q42"
     gene            1..7567
                     /gene="Agl"
                     /note="amylo-alpha-1,6-glucosidase and
                     4-alpha-glucanotransferase"
                     /db_xref="GeneID:362029"
                     /db_xref="RGD:1306376"
     exon            1..475
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            476..625
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     CDS             544..5142
                     /gene="Agl"
                     /note="amylo-1, 6-glucosidase, 4-alpha-glucanotransferase
                     (glycogen debranching enzyme, glycogen storage disease
                     type III); amylo-1,6-glucosidase,
                     4-alpha-glucanotransferase; amylo-alpha-1, 6-glucosidase,
                     4-alpha-glucanotransferase"
                     /codon_start=1
                     /product="glycogen debranching enzyme"
                     /protein_id="NP_001102034.1"
                     /db_xref="GeneID:362029"
                     /db_xref="RGD:1306376"
                     /translation="MEHSKQIRILLLNEMEKLEKTLFRLEQGFELQFRLGPTLQGKAV
                     TVYTNYPFPGEAFNREKFRSLDWENPTEREDDSDKYCKVHLQQSGSFQYYFLQGQEKS
                     GGGYIVVDPILRVGADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHF
                     TPLQALGLSRSCYSLADQLELNPDFSRPNRRYTWDDVGQLVEKLKREWNILCITDVVY
                     NHTAANSKWIHEHPESAYNLVNSPHLKPAWVLDRALWHLSCDVADGKYREKGVPALIE
                     NDHHMNCIRKIIWEDIFPRIQLWEFFQVDVQKAVEQFRRLLSQENRRVTKSEPKEHLK
                     IIQDPEFRRLGCAVDMNIALATFIPHDNGPAAIEECCNWFRKRLEELNSEKHHLTSCH
                     QEQAVNCLLGNVFYERLAGHGPKLGPVTRKYPLVTRYFTFPFEEMALSAEESLLHRPD
                     KACFLMAHNGWVMGDDPLRNFAEPGSNVYLRRELICWGDSVKLRYGNKPEDCPYLWAH
                     MKKYTEITATHFQGVRLDNCHSTPLHVAEYMLDAARKLQPNLYVVAELFTGSEDLDNI
                     FVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCLRPLMPAIAHALFMDI
                     THDNECPIVHRSAYDALPSTTVVSMACCASGSTRGYDELVPHQISVVAEERFYTKWNP
                     GASPSDTGDVSIHSGIIAARCAINRLHQELGAKGFIQVYVDQVDEDIVAVTRHSPSIH
                     QSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERNTKPYRKDENSING
                     MPNMTVELRERIQLHESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHA
                     QVAVGILRNHLTQFSSHFKSGSLAVDNSDPILKIPFASIASKLTLAELNQVLYRCESE
                     EQEDGGGCYDIPNWSSLKYAGLQGLMSVLAEIRPKNDLGHPFCENLRSGDWMIDYVSG
                     RLISRSGSIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDVAWKQMSSFV
                     QNGSTFVKHLSLGSVQMCGVGKCPCLPLLSPSLLDVPCRLNEITKEKEQCCASLAAGL
                     PHFSSGLFRCWGRDTFIALRGMLLVTGRYLEARNIILAFACTLRHGLIPNLLGEGTYA
                     RYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDSAPLPAGTLDQPLFEVI
                     QEAMQRHMQGIQFRERNAGPQIDRNMKDEGFNITVGVDEETGFVYGGNRFNCGTWMDK
                     MGESDRARNRGIPATPRDGSAVEIVGLCKSAVRWLLELSKKNIFPYHEVRVRRHGKVV
                     AVSYDEWNRKIQNSFEKLFHVSEDPSDPNEKHPNLVHKRGIYKDSYGASSPWCDYQLR
                     PNFTIAMVVAPELFTAEKAWKALEIAEGKLLGPLGMKTLDPDDMVYCGVYDNALDNDN
                     YNLARGFNYHQGPEWLWPIGYFLRAKLYFSKMMGPETAAKTVFLVKNVLSRHYVHLER
                     SPWKGLPELTNENGQYCPFSCETQAWSMAAVLETLYDL"
     exon            626..836
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            837..1003
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..1207
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1389
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1501
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1625
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            1626..1728
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            1729..1826
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            1827..1966
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            1967..2154
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            2155..2278
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            2279..2442
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            2443..2544
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            2545..2700
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            2701..2851
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            2852..2976
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            2977..3089
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            3090..3224
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            3225..3355
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            3356..3492
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            3493..3626
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            3627..3802
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            3803..3905
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            3906..4131
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            4132..4243
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            4244..4379
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            4380..4492
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            4493..4704
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            4705..4802
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            4803..4890
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            4891..5024
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
     exon            5025..7567
                     /gene="Agl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtaagtgtc tggaatgcgt ccggctctgg acgcgcattc tttctatcta tagcagctct
       61 gtacatcgca agccgccgca gctattcccg gggcagcaac tgcttccctc tcgaatcacc
      121 tccctattgg tggcttcaga cccgaatttg ggaacggggc gctcttccac ctgttcagca
      181 gcctgatctc ctggaggctg cagtgccatt tggagcttac agggccctct ggctcaggga
      241 cggaatttat gccactgatc tccagggttt tcgcggatgc attgcttttc tctgagaatg
      301 ttttaagggg ttttttggtc tgttctgttt tgatcagagt gtaagactct acgtctttgc
      361 ttcaggcttt cttattctgc tccaagagag aagaaacttc ttgcttgtcg gactttactg
      421 acaagatttc attctttctc tttgctcttc ttggctttaa ccatatctag gacatgggta
      481 actcattcca cttcggagtt cttttaattc tacggaaaga gttcagatcc cccagaggcc
      541 aaaatggaac acagtaagca gattcgaatt ttactattga acgaaatgga gaagctagag
      601 aagaccctct tcagacttga gcaaggattt gaactacagt tccgattagg cccaacttta
      661 caaggaaaag ctgttactgt ttatacaaat tacccatttc ctggagaagc atttaatcga
      721 gaaaaattcc gttccttgga ttgggaaaac ccaacagaga gagaagatga ttcggacaaa
      781 tactgtaaag ttcatctgca gcagtctggg tcttttcagt actacttcct tcaaggacag
      841 gagaaaagtg gcggaggtta catagttgtg gatcctattc tgcgagttgg agctgataat
      901 cacgtgctac ccttggattg tgttactctg cagacatttt tagcaaagtg tttaggaccc
      961 tttgatgagt gggaaagccg actacgggtg gcaaaggagt caggctacaa catgattcac
     1021 ttcaccccgc tgcaggctct cggactgtcc aggtcatgct attcccttgc cgatcagtta
     1081 gaattaaatc ctgacttctc aaggcccaat agaagataca cctgggatga tgttgggcag
     1141 ctagtagaga agctgaagag ggagtggaac attctttgta ttaccgatgt ggtctacaat
     1201 catactgctg ctaatagtaa gtggatccat gagcatccag aatctgcgta caatcttgta
     1261 aattctccac acttgaaacc tgcctgggtc ctagacagag cgctctggca tttgtcctgt
     1321 gatgttgcag atgggaagta cagagaaaaa ggagtccctg ctctaattga aaatgaccat
     1381 cacatgaact gcattcggaa aataatttgg gaggacattt tcccaaggat tcagctctgg
     1441 gagtttttcc aagtagatgt tcagaaagcg gttgaacaat ttagaagact gctctctcaa
     1501 gaaaacagaa gagtaactaa gtctgaaccg aaagaacatc ttaaaattat tcaggacccc
     1561 gaattcaggc ggctgggctg tgctgtagat atgaacattg ctctggcgac ctttatacca
     1621 catgacaatg ggccagctgc aattgaagag tgctgtaatt ggttccgtaa gagactcgag
     1681 gagttaaatt cagagaaaca ccacctcacc agctgtcatc aggaacaggc cgttaattgt
     1741 cttttgggaa acgtgtttta tgaacggctg gcgggccatg gccctaaact aggacccgtc
     1801 accaggaagt accctttagt taccaggtat tttactttcc cctttgaaga aatggccttg
     1861 tctgcagaag agtccctgct ccaccgccca gataaagctt gctttctgat ggcacacaat
     1921 ggctgggtga tgggcgatga cccgcttcgg aactttgctg agccaggttc caacgtttat
     1981 ttaaggagag aacttatttg ctggggtgac agtgtgaaat tgcgctatgg gaacaaaccg
     2041 gaggactgcc cttacctgtg ggcacacatg aagaaataca ctgagatcac tgccactcac
     2101 ttccagggag tgcgccttga caactgccac tccacgcctc tccacgtggc tgagtacatg
     2161 ctggatgctg ctaggaaatt acagcccaat ctttatgtag tggctgagct gttcacagga
     2221 agcgaagatc tggacaatat cttcgttact agactgggca tcagttcctt aataagagag
     2281 gcaatgagcg catataacag tcacgaagag ggcagattgg tctaccggta cggaggggag
     2341 cccgtcggat ccttcgttca gccctgtttg aggcctctta tgccagctat cgcgcatgcc
     2401 ctgtttatgg acatcaccca cgataatgag tgtccaattg tgcacagatc agcctatgat
     2461 gcgcttccaa gtaccacagt tgtctccatg gcgtgttgtg ctagtggaag tacaagaggc
     2521 tacgacgagc tagtgcctca tcagatttca gtggttgctg aagaacggtt ttacactaag
     2581 tggaatcctg gggcatcccc atcggataca ggagatgtta gcatccacag tgggattatt
     2641 gcagccagat gtgccatcaa cagactccat caagagcttg gagccaaggg tttcattcaa
     2701 gtgtatgtgg atcaagtgga tgaagacata gtggcagtaa ccaggcactc accaagcatc
     2761 catcagtctg ttgtggctgt atcgagaacg gcttttagga atcccaagac ttcattttac
     2821 agcaaagaag tgcctcaaat gtgcatccct ggcaaaattg aagaggtagt tctggaagct
     2881 agaactattg agaggaatac aaaaccttat aggaaagatg agaattcaat caatggaatg
     2941 ccgaacatga cagtggaact tagagaacgt atccagcttc atgaaagtaa aattgtcaaa
     3001 caagctggag ttgccacaaa gggtcccaat gaatatattc aggaaataga atttgaaaac
     3061 ctatctccag gaagtgttat tatattcaga gttagccttg atccacatgc gcaagttgct
     3121 gttggaattc ttcgaaatca cctgacccaa ttcagctccc attttaaatc tggaagcctt
     3181 gctgttgaca actcggatcc tatattaaaa atccccttcg cttccattgc ctctaaattg
     3241 actttggctg agctaaatca ggtactttac cgatgtgaat cagaagaaca agaagacggt
     3301 ggaggttgct atgatatacc aaactggtcg tcccttaagt atgcaggtct gcaaggatta
     3361 atgtccgtgc tggcagaaat aagaccaaag aatgacttgg ggcatccctt ctgtgaaaac
     3421 ttgaggtctg gagactggat gatcgactac gtcagtggcc ggctaatctc acgatcaggg
     3481 agtattgctg aagttggaaa atggttgcag gctatgttct tctacctgaa gcagatcccg
     3541 cgatatctca tcccatgtta ctttgatgct atattaatcg gtgcatatac cactctgctg
     3601 gatgtagcct ggaaacagat gtcaagcttt gttcagaatg gctcgacctt cgtgaagcac
     3661 ctgtccctgg gttctgtcca gatgtgtgga gtcgggaagt gtccttgtct gccgctgctt
     3721 tcaccctcac tcctggatgt gccgtgcagg ttaaatgaga tcacgaagga gaaagagcag
     3781 tgctgtgctt ccttggctgc aggcttacct cacttttctt ctggtctttt tcgctgctgg
     3841 gggagggata ctttcattgc acttcgaggg atgctgctgg ttactggtcg ctacctagaa
     3901 gccaggaata ttattttagc atttgcttgt accctgaggc atggtctcat tcctaacctc
     3961 cttggcgaag gaacgtatgc caggtacaac tgtcgtgatg ccgtgtggtg gtggctgcag
     4021 tgcattcagg actattgcaa gatggttcca aatggtctag acatcctcaa atgcccagtt
     4081 tccagaatgt atccaacaga tgactctgca cctttgcctg ctgggactct ggatcagcct
     4141 ttgtttgaag tcatacagga agctatgcag aggcacatgc aaggcattca gttccgagag
     4201 cggaatgccg gtccacagat cgatcgaaac atgaaggatg agggtttcaa cataaccgtg
     4261 ggggttgatg aagaaacagg atttgtttat ggaggaaatc gcttcaactg tggcacatgg
     4321 atggataaaa tgggagagag tgacagagct agaaacagag ggatcccagc caccccaaga
     4381 gatgggtctg ctgtggaaat cgtgggcttg tgtaaatctg ctgttcgttg gttgctggaa
     4441 ttgtccaaga aaaacatttt tccttatcat gaagtcagag taagaagaca tggaaaggtt
     4501 gtagcagtct cctatgatga gtggaacaga aaaatacaaa acagttttga aaagctcttt
     4561 catgtttccg aagacccttc agatcctaac gagaagcatc cgaatctggt tcacaagcgg
     4621 ggcatctaca aggacagcta cggtgcgtca agtccttggt gtgactatca gctcaggccc
     4681 aactttacca tagcaatggt cgtggcccct gagctcttta ctgctgaaaa ggcttggaag
     4741 gctttggaaa ttgcagaagg aaaattgctt ggtccccttg gcatgaagac tttggatcca
     4801 gatgacatgg tttactgtgg agtctatgac aatgccttag acaatgacaa ctacaacctt
     4861 gccagaggtt tcaattacca ccaaggacct gagtggctat ggccgattgg gtattttctt
     4921 cgtgcaaagt tgtatttttc caaaatgatg ggcccagaga ctgctgcgaa gactgtattt
     4981 ttggttaaaa atgttctttc tagacattat gttcatcttg agagatcccc atggaaagga
     5041 cttccagagc tcaccaatga gaatggccag tactgccctt tcagctgtga gacacaggca
     5101 tggtcgatgg ctgctgttct cgaaaccctc tatgatctat agttggctcg tagatactta
     5161 gtaattgtgt gaacacttga cattattgaa tgcaaggtca taaggaaatg taagctcaac
     5221 tcattttaaa aatcccattc atagccaggg agtggtggtg tacaccgttg atcccagcac
     5281 tcgggaaaca gaagcaggca gatctcttga gttcgataga ggccagcctg gtctacaaag
     5341 aaagttcctg gacagccagg ggtacacaga gaaaccctgt gtcgaaaaac caaaaattaa
     5401 acaaacaaaa aaaaatagat tttttttggc tttttttctt aaagaatatc atgtgtactg
     5461 gggattacac gaaggacctc atgtatgtta gacaagcatt ctaccaactg aacttcatcc
     5521 tgtgtcctat tttttctata ttcttttgat ttgaatcgaa gaaaaatgat cttttcccat
     5581 agaaggttac agggaaaagt attcttcaaa gcagggttta aaaacagtgt attatcttca
     5641 gtttagagga agaagtcctg ctgtctgttg gcacactcca caggctgtgt catgaatgct
     5701 ctaacgtttg ctacagcagt cttaatacca tgcctaatgc agtcagtgca cacttgttaa
     5761 atgttttatg aatgtggaat tatggaagtt tccacccaca gtatatgttc atagctggag
     5821 cacagagctt caaaatgtgc tttatttttc atggacaagt tatgttttta atatagtaaa
     5881 tgccaactat acttaatata gcctatttgt gttaaagagt aattggtcgt aataaaacag
     5941 accactagaa cataagacaa ttctgtaaaa ttagttctaa tttcccacta tgagatagtt
     6001 tacattttca aaatggaaat tactgggcat atttatgaaa tttttcaagg gggaaaaaag
     6061 cttagagctg tacttggtga cacagcttgc ttagcatggt caaggccttg agttctatcc
     6121 ctaaaaccat caagaaagga aggaaggagt ataagagggg agggagggag gaaagaaaga
     6181 gggaagattt aaaatagagc catattaggt tatcaacaat agggtcacca tccacctcag
     6241 aaaatcctta gggtacagtg cttatactga ggactgttga tgaaaggctg gtgctgtgtt
     6301 gggcatggtc tatgtgaaag tctaggaggt gtattttacc ttatcccagc cacagtaatt
     6361 agactggaaa aggataatgg ccatttgact gaagaactct taggtgcaac gcttcgttcc
     6421 tgtgtgatgc tgcagaaagt ttcccaaacg gtccgtgcct tggtttgtca catatcaaac
     6481 caatcttact ctgctaagtg aaaggtaaac ttagcagttg aaccagcatg ctgtggtatt
     6541 gtagtgagtt ttcatagatg actgaggagg cagggagcct gtcatttagt acatcaccta
     6601 agtggtaatc atttccactg tgtcctaaac ggctctgagt actgagcaaa tgtgtatatg
     6661 tctgtgtgtc aaaataaaag ttttttttta aaggactctc tttgctttcc ttcgtcttct
     6721 ttactgtaaa ttttccctgt cctcatgagt ggtgctcaga gatttacctt ttataggata
     6781 taggagcagg gagaggagga agagagaagg ctgtctggag atttattaaa gtagccatgt
     6841 gtaaattagg agtgaagtaa gctttcagtg tatccctaag tctgttagca tctgtactcc
     6901 tttgatatat cttgagtaca gtgaattttt atttacattt taccaactca caaatatagt
     6961 aacaaatgga tgtgaacatt tactttctga aaaagccaga caatttttgc tttattttat
     7021 ttatttattt atttatttat ttatttattt atttattttt ggagctgggg accgaaccca
     7081 ggaccttgcg cttgctaggc aagcgctcta ccactgagct aaatccccaa ccccagattt
     7141 atttattata tatgagtaca atgtagctgt cttcagacac accagaagaa ggcttcagac
     7201 ctcattacaa atggttttga gccaccatgt ggttgctggg aattgaactc aggacctctg
     7261 gaagagcagt cagtgctctt aaccactgag ccatctctcc agctctgctt cattctttta
     7321 tactacagat tctatgtctt tacttttaga tagaaggtgc taacataaga atctataatt
     7381 ccacgttgtt cgaaatggat cagtcagact tgctgcattt acttacttaa ccctccatac
     7441 accagtaccg ggaagtcagg gaatcagggt agttagcttt tgctggtttt ttctatttct
     7501 gtccaccctg gattataaag gagtgatgac attagagctg atgcttcttt aactgggtct
     7561 catgtga
//
