LOCUS       NM_001135596            7753 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus ArfGAP with FG repeats 1 (Agfg1), mRNA.
ACCESSION   NM_001135596 XR_005463 XR_009641
VERSION     NM_001135596.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7753)
  AUTHORS   Catena,R., Ronfani,L., Sassone-Corsi,P. and Davidson,I.
  TITLE     Changes in intranuclear chromatin architecture induce bipolar
            nuclear localization of histone variant H1T2 in male haploid
            spermatids
  JOURNAL   Dev Biol 296 (1), 231-238 (2006)
   PUBMED   16765935
REFERENCE   2  (bases 1 to 7753)
  AUTHORS   Brockschnieder,D., Sabanay,H., Riethmacher,D. and Peles,E.
  TITLE     Ermin, a myelinating oligodendrocyte-specific protein that
            regulates cell morphology
  JOURNAL   J Neurosci 26 (3), 757-762 (2006)
   PUBMED   16421295
REFERENCE   3  (bases 1 to 7753)
  AUTHORS   Khidekel,N., Ficarro,S.B., Peters,E.C. and Hsieh-Wilson,L.C.
  TITLE     Exploring the O-GlcNAc proteome: direct identification of
            O-GlcNAc-modified proteins from the brain
  JOURNAL   Proc Natl Acad Sci U S A 101 (36), 13132-13137 (2004)
   PUBMED   15340146
REFERENCE   4  (bases 1 to 7753)
  AUTHORS   Kierszenbaum,A.L., Tres,L.L., Rivkin,E., Kang-Decker,N. and van
            Deursen,J.M.
  TITLE     The acroplaxome is the docking site of Golgi-derived myosin
            Va/Rab27a/b- containing proacrosomal vesicles in wild-type and Hrb
            mutant mouse spermatids
  JOURNAL   Biol Reprod 70 (5), 1400-1410 (2004)
   PUBMED   14724135
REFERENCE   5  (bases 1 to 7753)
  AUTHORS   Kang-Decker,N., Mantchev,G.T., Juneja,S.C., McNiven,M.A. and van
            Deursen,J.M.
  TITLE     Lack of acrosome formation in Hrb-deficient mice
  JOURNAL   Science 294 (5546), 1531-1533 (2001)
   PUBMED   11711676
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1, FN806187.1, FM042993.1, FM075043.1, FM069945.1,
            FM099288.1, FM032550.1 and FM122674.1.
            
            On Mar 3, 2021 this sequence version replaced NM_001135596.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099202.1, SRR26360172.1317248.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-22                JAXUCZ010000009.1  91572962-91572983
            23-675              FN806187.1         1-653
            676-1049            FM042993.1         265-638
            1050-1324           FM075043.1         400-674
            1325-1409           FM069945.1         363-447
            1410-1480           FM099288.1         289-359
            1481-1483           JAXUCZ010000009.1  91616081-91616083
            1484-1799           FM099288.1         360-675
            1800-2264           FM032550.1         132-596
            2265-2866           FM122674.1         69-670
            2867-7753           JAXUCZ010000009.1  91625802-91630688
FEATURES             Location/Qualifiers
     source          1..7753
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q34"
     gene            1..7753
                     /gene="Agfg1"
                     /note="ArfGAP with FG repeats 1"
                     /db_xref="GeneID:363266"
                     /db_xref="RGD:1560041"
     exon            1..442
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     CDS             276..1961
                     /gene="Agfg1"
                     /note="arf-GAP domain and FG repeats-containing protein 1;
                     nucleoporin-like protein RIP; HIV-1 Rev-binding protein
                     homolog"
                     /codon_start=1
                     /product="arf-GAP domain and FG repeat-containing protein
                     1"
                     /protein_id="NP_001129068.1"
                     /db_xref="GeneID:363266"
                     /db_xref="RGD:1560041"
                     /translation="MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTV
                     GSFVCTSCSGSLRGLNPPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSS
                     AIPDFRDPQKVKEFLQEKYEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPL
                     KSLLGESAPALHLNKGTPTQSPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTAT
                     ANFANFAHFNSHAAQNSANAEFANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAG
                     SVNANFAHFDNFPKSSSADFGSFSTSQSHQTASTVSKVSTNKAGLQTADKYAALANLD
                     NIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSHSSASSDKYAALAELDSVFSSAATSNN
                     AYTSTSNASSSVFGTVPVGASPQTQPASSGPAPFGATPSTNPFVAATGPSAASSTNPF
                     QTNARGATAATFGTASMSMPAGFGTPAQYSLPTSFSGSFQQPPFPAQAAFPQQTAFSQ
                     QPNGAGFATFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL"
     exon            443..536
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            537..652
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            653..815
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            816..969
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1089
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1299
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1480
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1557
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..1650
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1809
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1901
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1902..7753
                     /gene="Agfg1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttctttcccc cttaggagaa gtcgggaagg tggcagcggc ggcggtggcg gttgtcccgc
       61 ccggccggtt ggtgtgaccg gtcggcgcgt gctgcgcagc ttccgagcct cgtccagccg
      121 ggaggaaccg agcagagacc gagaccggag tccgcgcggg cggagggcgg aggcggcggc
      181 ggcggcggcc agggcggccc gtgggaggga gcgcggggcc ccggcagcgc cgccggctcc
      241 cggccctgcc ggcctcctcg gtcggagccg cggccatggc ggccagcgcg aagcggaagc
      301 aggaggagaa gcacctgaag atgctgcggg acatgacggg gctgccgcac aaccgcaagt
      361 gcttcgactg cgaccagcgc ggccccacct acgtgaacat gacggtcggc tcgttcgtgt
      421 gcacctcttg ctccggcagc ctgagagggt taaatccacc tcacagggtg aagtctatct
      481 ccatgacaac atttacacaa caggaaattg aattcttgca aaaacatgga aatgaagtct
      541 gcaaacagat ttggctagga ttatttgatg atagatcttc agcaattcca gacttcaggg
      601 atccacaaaa agtgaaagag tttctacaag agaaatatga aaagaaaaga tggtatgttc
      661 ctccagaaca agccaaagtg gtggcatcgg ttcacgcttc tatttcaggg tcctctgcca
      721 gcagcacaag cagcacccct gaggtcaaac ccctgaaatc tctgttggga gagtctgcac
      781 cagcactgca cttaaataag ggcacaccta ctcagtcacc agttgtaggt cgctctcagg
      841 ggcagcagca ggagaagaag cagtttgacc ttttgagtga ccttggctca gacatctttg
      901 ctgctccagc gcctcagtcg acagctacag ccaactttgc taactttgca cactttaaca
      961 gtcatgcagc gcagaattct gcaaatgcag agtttgcaaa ctttgatgca tttggacagt
     1021 ctagtggttc gagtaatttt ggaggtttcc ccacagcaag tcactctcct tttcagcccc
     1081 aaactacagg tggaagtgct ggatcagtaa atgctaattt tgctcatttt gataacttcc
     1141 ccaaatcctc cagtgctgat tttggatcct tcagtacatc ccagagtcat cagacagcat
     1201 caactgttag taaagtttca acaaacaaag ctggtttaca gacagcagac aaatatgcgg
     1261 cacttgctaa tttagacaat atcttcagtg ctgggcaagg aggtgatcaa gggagtggtt
     1321 ttgggaccac cggtaaagct cctgttggtt ctgtggtttc agttcccagt cattcaagtg
     1381 catcttctga caagtatgca gccctggcag agttagacag cgtgttcagt tctgcagcca
     1441 cctccaataa tgcgtacaca tccaccagta atgctagcag cagtgtcttt ggaacagtgc
     1501 ctgtgggtgc ctctcctcag acacagcctg cttcaagtgg gcctgctcca tttggagcta
     1561 cgccttctac gaatccattt gttgctgcta ctggtccgtc tgcagcgtca tctacaaatc
     1621 catttcagac caatgccaga ggagcaacag cggcaacctt tggcactgca tctatgagta
     1681 tgccagcagg atttggcact cctgctcagt acagtctccc caccagcttt agcggcagtt
     1741 tccagcagcc tcccttccca gcccaagcag ctttccctca gcagacagcc ttttctcagc
     1801 agcccaatgg tgcaggtttc gccacatttg gacaaacaaa accagtggta acaccttttg
     1861 gtcaagtagc agctgctgga gtgtctagta atccttttat gactggtgca ccaacaggac
     1921 aatttccaac aggaagctca tcaaccaatc ctttcttata gccttatata gacactgtac
     1981 tggaacgaac ttttatgtca tcatattaca tctcctcgcc tcttgcactg ttgtcttgtt
     2041 tcactgacct tagctttaaa catgagagaa gtctttaaaa tgcctgcatt gtgtattaaa
     2101 caccaggtaa tatgtgcaaa acagagggct cagcaacaac ttttcacttg tgaattggca
     2161 ggaaaaggta gcggcatcat gtaagttaaa aattggctaa cgttaagtta ttgcagatcc
     2221 cacattcatt atgctgcagc actgtacata tttttcttag aaattagcta tttgtgcata
     2281 tcagtatttg taactttaac acattgttat gtgagaaatg ttactgggga aatagatcag
     2341 ccacttttaa ggtgctgtca tctagcttga aatgaatgat taaaatcatt tgaaacattg
     2401 cttctggaaa attcagattg gaaggttcta ttcgttcttg aatttttcct tctgaagagc
     2461 tcttctattc gtacatggct aagttcttta aggatgtgga ggacacctgt ctgcggctaa
     2521 agctgatcat gttttgctac agtttgcagg tgaacaaaat aaatactaga aaatatgcta
     2581 ttgttttttg tgttcttgct gcaatgcctt taccaaagtg gccttaaata atgagtagtg
     2641 agttgagaac atcttgaact cttaaagact tctagtgact aactttttta aaaaggccat
     2701 gtagaaaatt tattaaaact actaggactg ctatattcag gaatgtgaca gtggaaaagc
     2761 atttaaatgt agcttgtcag attcaccatg ctacttctaa tttctctgca acttcttaat
     2821 tttgtgaaat ttgtaaatat ggagagaatt tgcatgtatg tgtatttaca aatattttta
     2881 aaagatcttg aattctcaga ctgcaaaatg cctactttaa ctcttttccc ttctgtgtgc
     2941 attgtctctg aatgtactgg aatcagacgt gcactgaccg tgaccgtgac gtggtcgcac
     3001 cagaggtccc ctcactttct ggacagacta atactgtctg tcaaacgttt gtttgtgttt
     3061 gttttgggga taaaggaaaa ggaacccgat gttaccttaa agtgatgaaa tactgtgtaa
     3121 aatggtagcc atactaatat tagtttatct ttttgttaat attcaaatga acttgtttaa
     3181 atatttatat gtagtaatgc ctcattcatc ccgggataat ctggcccttt catcaaaacc
     3241 aaatacaact aagaattgaa atgattaaaa aaaatctttg aacaataccc ctaagttatg
     3301 aattctgtat gtagagcata tgtttctttg aatgtgttta attgtttgat aatttgattt
     3361 atattggtcc atagcatatt agtgttgatg aacggagggg atccacaaat cggaggaaga
     3421 aagagcatgg atggccaggc cccctaggga cagccagctc aggcgagagg tggtgactct
     3481 gccgtcaaaa gctggaactg cacacacaat gccggttaga aagtgacttg aaatgtttaa
     3541 gggttggttt gaagtgatac aagcaccact ttcctcacac attttattca ttttggatgt
     3601 atttttgcag tgatggctgt tatcatactc taaagtctgg gtgtttactt gaagcactgt
     3661 ggtcgggtgc cctcccatcg ggaagttgtg ctttatgtgt acttgacagg tggtgtgccc
     3721 aagcctgagg acccgttagt gctgctcagc tggcctgaac tctgggcagt ctcgaactct
     3781 ctgtacagtt tggggatctc atctgttttc gtggagggaa aatttaaatg tctctaaact
     3841 tttgtttggg attgtattag atcaaatcaa ttcacatgta caagttaaac tatataatta
     3901 taggccgtta cccaaatacc ccagcagcct ttccacctag taagtaaatt aaacagttgt
     3961 tattcaaagt aactttaaag actatttttt ctagtagttc ttgagatgtg taattaaatg
     4021 gggtgttgtt ttgactttca gtgagtgcct atagcacaaa cacaagtacc gaggttcaga
     4081 acagttcagt gttaaagcgg gttttctcag gcttgtgttt gggtttcttc tcattttcgg
     4141 cactgagtga gcactgggag gacggtgctc agtggcagct gggggtcgca cactttgggc
     4201 tcgtgattgc tcacaacagg cctcctccct ctgtctccga tgagcatgac gttctgtatt
     4261 aataagttca aaaacatctt gatccatctt gtttttatga cttaaggagt attttatttt
     4321 agacttttta aataggttgt catcttccat aaaatcattt gttctgtaaa aacacccgtt
     4381 atatgggagg tacttggtac ctcttcctgt cagttgcaaa gtcgagagag taactgtctg
     4441 cttacagtca ctgtgccagc atttatgaaa catactgttt tacagtcaca gtttttataa
     4501 ctgtcgatga tcctccaaag agcttttgtt tacaaaactt gactctttca taggttagta
     4561 tattatagat aagtacagag ggatttctaa agcatgcctt cttttagata tgactgcaat
     4621 agtccgacta cttgttaccc ttgtcagact ctcttgtagc ctggcaggga ggcactggaa
     4681 actgctatgt atacctgtgg gttccagatg gggaaaaagg cacaaaccac cttagaatta
     4741 ataggaaagc agccagacct ggcgcaggta ttcagggtcc ccagataaca ttgaaaacac
     4801 agcactttaa gtttttatgt tcctgatcca tgtacctctg tctggggaaa ccttgctcct
     4861 tctgaattta aggggttgtt tcctttgatg aaattccagt tgaaatcaat gttaaatatt
     4921 ttaatgtact aatggtgatg gtgtgtgtgt ggtggttttt acgccctaag tggtttcttc
     4981 tctctgctca tgtgttagaa tctacaaggc atagaacagg taagcgagag taaccgtttc
     5041 tattcttgga gaaagtgcta ttgggttaaa ttgtgctttc acatttaggt gtgcgtagag
     5101 cttgtctcgt taccaagtta ctttgtattc tcaaaaacct taaatcattt aacctgagtt
     5161 ctttgatact ttgatgagat aagtgctgtt tgctctatag agtccagttt gcttctttta
     5221 aatgcagggt ctctacacag ccctgactgt cctggaactc actctgtagg ccagggtacc
     5281 tcagactcac agggattgtc cgcctatgca ccacacccac ctagcccgct gagtcttagt
     5341 aacctgtaga gtagagggct gagggatagg acagctttct ttgcatctca ggttgggaca
     5401 gcttaccttt agttatgtag tctattcccc tacagtttta aatttgctct ttaaaaggtt
     5461 attaaaactg tgtataagtt agcttattgt attgaattta tcactctgtt gaactttgtg
     5521 tattttaaag cagtgtcatt accttgcttt tgtatggttg tatttgaaca aatggagatg
     5581 gactgtgacc aggactgtgc tggtgagtgc ttgccagccg tctctgaaga gaagatgagg
     5641 caacctgcct tgtagtgggc tggggtcgtg aaataccgtt tgaaaggagc acgagtggat
     5701 gtgctgagcc tgagttagac agctctggta cagcactcat gtgcagccca caactcactg
     5761 gatttactgc tcctctgatg attagtccag gctttgaaaa cctttgtttt atatttttac
     5821 tgattcattc tgtaagcata taggtgctag tttatttctg aaagtccact ataatttgga
     5881 aatgtccaag tgctgtgcaa gattggaaaa gacgatctag tctttcctgg tgtagggctg
     5941 tccaggcgat tgctgtctgc tgacgtgcca ccgtagtact tcttagaact tggagcgagc
     6001 ctgtactcgg caaaggttcc ctatccccac atctcactgc ttccctggcc ttgcagtgac
     6061 cagatcccgg acagggtgga aggtgagaga gctttcctct ggcacctttt cctttcagtt
     6121 tagtctttcc agtgaagact tctgccaaga aggtgtatct aatgtcctat ccattctgca
     6181 tgtttattcc tacagttaga atccattgaa tctacacttg tccagtacct aggtctgtgg
     6241 aaacaatgtt ttgattcaga attttataaa aaaaaaatcc cagacagaat attttaattg
     6301 ctgatagacg tgcccattgg attaattttt aaaattggtt tgttctccag agtcttgacc
     6361 acttgttgtc tgagtcacaa tcttaaaaaa ggagccttgt gattaggaca cttggcagca
     6421 aagtgtaaat gaatgttaca tagtgtccta gagtgtggtg aatagaacca gatctttaaa
     6481 gacgtagaag tctttatatg ttctaaataa catgcttagg gtttttgcaa ttatgaagtg
     6541 tacacagggt ataaggtaaa tgtttccctc tgcaacttga tttttgcact tcaggggaat
     6601 acttagtgtt ccttgtattc tttgtagttt tcaggaatgc tgactgtttt gtctacatat
     6661 ctgtgcatgc ctttcatggt tctgcctttt aaaaatagag agttttgcaa ccttttcctt
     6721 tggtttaact tggacacgtt tccattttgc cacatgcagc actgtcccat tgtgtgaatg
     6781 gcatcaaaat ccaggagtgg atgtccttta caggaacatt tttgtatgta tatgcataca
     6841 taacgtatac atgtatacat gtacacatgt atatacacac atatacatat acatatatat
     6901 gtacatgtgt atgtttatat gaaaattctt gattttgtct gatagggaac tttcaacaaa
     6961 acagaaaatt ctattttgag gctcaccagc tatttatata caatatttta tttccacctg
     7021 agaaaatttt aaggtctctc aaatagttgt aaaatccagc atttaaatta aaccaggagg
     7081 gcattcagtt tactcactga gactatggaa tcttatgtcg tattctatac cttgctctcg
     7141 ctgtcacccc tacctgtgac ccctaaggtt tgtaagagtg gcttgaagcc tcgagtattg
     7201 tgtatctcca cagcctccgt gattggagtg aagtttatat ttatgaaaga aagtacaagt
     7261 ctattttttc acaattagtg tcttcagaat taacttttgc tttggaaaac atttcgggaa
     7321 caactcataa aagttttgat tttggcatct tttagtatta gttatgcata gagtttgctt
     7381 cctagagaag tgtttttcat ggagaacact tacctaatca ctgacttgag aacgcctcta
     7441 catgtggagg gtacaagttc agcgtgacgg agttcaaagg gcagcagtca ggggccagcc
     7501 ctctgtgggc tgtatttgga aaacgttaac atgctaaggt tttcgaggct cagtcttggt
     7561 gcaggaagtg gttttaggta gacactgatt ttgataattg tttcttttct cctttggaga
     7621 tgctgaggat tggaccctca gtcttgcaca tgctaggcaa tgctctacaa ctaagtccag
     7681 ctaatttctt gttcattgta aaatattgtt gaaataattt tttaaaaata aagacatgaa
     7741 tttgtgtacc att
//
