LOCUS       NM_001350232            2872 bp    mRNA    linear   ROD 30-AUG-2020
DEFINITION  Rattus norvegicus ATP/GTP binding protein-like 4 (Agbl4), mRNA.
ACCESSION   NM_001350232
VERSION     NM_001350232.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2872)
  AUTHORS   Magiera MM, Bodakuntla S, Ziak J, Lacomme S, Marques Sousa P,
            Leboucher S, Hausrat TJ, Bosc C, Andrieux A, Kneussel M, Landry M,
            Calas A, Balastik M and Janke C.
  TITLE     Excessive tubulin polyglutamylation causes neurodegeneration and
            perturbs neuronal transport
  JOURNAL   EMBO J. 37 (23) (2018)
   PUBMED   30420556
REFERENCE   2  (bases 1 to 2872)
  AUTHORS   Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, Xia P, Du Y, Meng S,
            Huang G, Qin X, Wang Y, Yan X, Li C, Hao J, Zhu P, He L, Tian Y and
            Fan Z.
  TITLE     Klf4 glutamylation is required for cell reprogramming and early
            embryonic development in mice
  JOURNAL   Nat Commun 9 (1), 1261 (2018)
   PUBMED   29593216
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2872)
  AUTHORS   Xia P, Ye B, Wang S, Zhu X, Du Y, Xiong Z, Tian Y and Fan Z.
  TITLE     Glutamylation of the DNA sensor cGAS regulates its binding and
            synthase activity in antiviral immunity
  JOURNAL   Nat. Immunol. 17 (4), 369-378 (2016)
   PUBMED   26829768
  REMARK    Erratum:[Nat Immunol. 2016 Apr;17(4):469. PMID: 27002845]
REFERENCE   4  (bases 1 to 2872)
  AUTHORS   Tort O, Tanco S, Rocha C, Bieche I, Seixas C, Bosc C, Andrieux A,
            Moutin MJ, Aviles FX, Lorenzo J and Janke C.
  TITLE     The cytosolic carboxypeptidases CCP2 and CCP3 catalyze
            posttranslational removal of acidic amino acids
  JOURNAL   Mol. Biol. Cell 25 (19), 3017-3027 (2014)
   PUBMED   25103237
REFERENCE   5  (bases 1 to 2872)
  AUTHORS   Rodriguez de la Vega Otazo M, Lorenzo J, Tort O, Aviles FX and
            Bautista JM.
  TITLE     Functional segregation and emerging role of cilia-related cytosolic
            carboxypeptidases (CCPs)
  JOURNAL   FASEB J. 27 (2), 424-431 (2013)
   PUBMED   23085998
REFERENCE   6  (bases 1 to 2872)
  AUTHORS   Rogowski K, van Dijk J, Magiera MM, Bosc C, Deloulme JC, Bosson A,
            Peris L, Gold ND, Lacroix B, Bosch Grau M, Bec N, Larroque C,
            Desagher S, Holzer M, Andrieux A, Moutin MJ and Janke C.
  TITLE     A family of protein-deglutamylating enzymes associated with
            neurodegeneration
  JOURNAL   Cell 143 (4), 564-578 (2010)
   PUBMED   21074048
REFERENCE   7  (bases 1 to 2872)
  AUTHORS   Kalinina E, Biswas R, Berezniuk I, Hermoso A, Aviles FX and Fricker
            LD.
  TITLE     A novel subfamily of mouse cytosolic carboxypeptidases
  JOURNAL   FASEB J. 21 (3), 836-850 (2007)
   PUBMED   17244818
REFERENCE   8  (bases 1 to 2872)
  AUTHORS   Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M,
            Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail
            S, Li P and Sutton G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res. 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AABR07049596.1, AABR07049606.1, AABR07049608.1, AABR07049617.1,
            AABR07049622.1, AABR07049625.1, AABR07049626.1, AABR07049628.1 and
            AABR07049635.1.
            
            [WARNING] On Jun 29, 2023 this sequence was replaced by
            NM_001350232.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00052296,
                              SAMD00052297 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-183               AABR07049596.1     17132-17314
            184-306             AABR07049606.1     7180-7302
            307-431             AABR07049608.1     36975-37099
            432-526             AABR07049617.1     7631-7725
            527-743             AABR07049622.1     17258-17474
            744-783             AABR07049625.1     16165-16204
            784-873             AABR07049626.1     77362-77451
            874-988             AABR07049626.1     87065-87179
            989-1100            AABR07049626.1     109474-109585
            1101-1253           AABR07049628.1     4742-4894
            1254-1416           AABR07049628.1     6874-7036
            1417-1513           AABR07049635.1     8225-8321
            1514-2872           AABR07049635.1     13759-15117
FEATURES             Location/Qualifiers
     source          1..2872
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="mixed"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q35"
     gene            1..2872
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /note="ATP/GTP binding protein-like 4"
                     /db_xref="GeneID:100911395"
                     /db_xref="RGD:6493177"
     exon            1..183
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..1634
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /note="cytosolic carboxypeptidase 6-like 1"
                     /codon_start=1
                     /product="cytosolic carboxypeptidase 6"
                     /protein_id="NP_001337161.1"
                     /db_xref="GeneID:100911395"
                     /db_xref="RGD:6493177"
                     /translation="MAERSQTAPEAGNDTGNEDAIGGNVNKYIVLPTGYSGQPKRGHL
                     TFDACFESGNLGRVEQVSDFEYDLFIRPDTCNPRFRVWFNFTVENVKELQRVIFNIVN
                     FSKTKSLYRDGMAPMVKSTSRPKWQRLPPKNVYYYRCPDHRKNYVMSFAFCFDREDDI
                     YQFAYCYPYTYTRFQHYLDSLQKKNMDYFFREQLGQSVQQRQLDLLTITSPENLREGS
                     EKKVIFITGRVHPGETPSSFVCQGIIDFLVSQHPIARVLREHLVFKIAPMLNPDGVYL
                     GNYRCSLMGFDLNRHWLDPSPWAHPTLHGVKQLIIKMYNDPKTSLEFYIDIHAHSTMM
                     NGFMYGNIFEDEERFQRQSIFPKLLCQNAEDFSYTSTSFNRDAVKAGTGRRFLGGLLD
                     HTSYCYTLEVSFYSYIIGGTTAAVPYTEEAYMKLGRNVARTFLDYYRLNSLVEKMTIP
                     MPRLRKEKALPCKHPPLRGSTSNFPIGKGDKKNSLNHKDPSNPF"
     exon            184..306
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            307..431
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            432..526
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            527..743
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            744..783
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            784..873
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            874..988
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1100
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1253
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..1416
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1513
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..2872
                     /gene="Agbl4"
                     /gene_synonym="Ccp6l1; RGD1559973; RGD1564161"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccggccgct caggggcggc tggtttccct ggcaaccgct gcgcagcgtc ttcctgaggg
       61 agccttttct gtcagcccgc ggatcccacc gctcgctccc cagggcccgg tggttttagc
      121 gtgggctcat tgactgacag acaacaaaaa tggcggagcg gagccagacg gcgccagagg
      181 caggcaatga tacaggaaat gaggatgcca ttggagggaa tgtgaacaag tacatagtgc
      241 ttccaactgg ttactctgga cagcccaaga gaggacatct tacctttgat gcttgctttg
      301 aaagcggtaa cctcggccgg gttgagcaag tctctgattt tgagtatgat ctgttcatta
      361 ggccggacac ctgtaatcct cgcttccgag tctggttcaa ctttactgtt gaaaatgtga
      421 aagaattaca gagggtcatt ttcaacatcg ttaacttcag taaaaccaag agtctttata
      481 gagatgggat ggcaccaatg gtgaaatcta ccagcagacc aaaatggcaa aggctaccac
      541 caaaaaatgt ttactactat cgctgcccag accacaggaa gaattatgtg atgtcctttg
      601 cattctgttt cgacagagaa gatgatattt accagtttgc ttattgctac ccatatacat
      661 atactcgctt ccagcactac ctcgacagcc tacaaaagaa aaacatggac tacttcttcc
      721 gggaacagct tggacagagt gtgcaacaga ggcagcttga cctcctgacg ataaccagcc
      781 cggagaatct ccgagaaggg tcagaaaaga aggtgatatt catcacaggg cgagtccacc
      841 caggtgaaac accatcttca tttgtgtgcc aagggatcat tgacttcctc gtaagtcagc
      901 atccaattgc ccgtgtcctg cgagaacatt tggtcttcaa gattgcacca atgcttaacc
      961 ctgatggagt ctacctgggc aactacaggt gctccctgat ggggtttgac ctgaatcgtc
     1021 actggctgga tccctctcca tgggcccatc ctactctgca tggagttaag cagctcatca
     1081 tcaagatgta caatgaccca aaaacaagcc tagagttcta tattgacatc catgcccact
     1141 ccactatgat gaacggcttc atgtatggca acatctttga ggatgaggaa aggttccaaa
     1201 ggcagtccat tttcccaaaa ctcctttgcc agaatgccga ggacttctcc tatactagca
     1261 catccttcaa ccgggatgct gtgaaagcag gaactggccg gcgtttcctt ggtgggcttc
     1321 tggatcacac atcatactgc tataccctag aggtttcctt ctacagttat atcattgggg
     1381 gtactacagc tgctgtgccc tacactgaag aagcctatat gaaactggga cggaacgtag
     1441 caagaacatt tctagattat tacaggctga actcccttgt tgagaagatg acaatcccaa
     1501 tgccaagact tcggaaagaa aaagcccttc cttgcaagca cccacccctg cggggctcaa
     1561 ccagcaattt ccccattggc aaaggggaca agaagaactc actgaaccac aaagacccat
     1621 caaacccctt ttaaagacat ggcgccagga ggcatcgtgg gtacaggaac atgcatttct
     1681 tgctggggca tgaaattaag tgccctttcc tggtttccaa ggcaggggtt ttcaggataa
     1741 tgcacaagct agtgaaagag agtcagggaa aaagagaaat tttatcatcg atttttccct
     1801 tttaccaatg ggaaatcaat tgtgagcctt caactcgggg ccgaacagaa tgtgagaatg
     1861 gaatcaggtc agcacaggtt ttatctgcca tggcaaacct atacacccct ctcaagagac
     1921 cccatgggca gttccctggt agcccctctt cacattttaa agtcacagag tcatgatccg
     1981 aatgacttca cttaaaacag gttgcagttg tttctagttt aggagttcag cctccatatt
     2041 ttctgatcca aagcaacaaa aacacccatg caaaacaatg gcaaacacgc ctttgggaac
     2101 aacggggcag aatttttgaa atcagagtgg tctgaaaaat acggtcgtat ctataagctt
     2161 tctcgctccc tcaagcccca gcatgtaact tcagaaagct gttctgaaag cgatttttca
     2221 acttcctggc tagtttaatt gaatttctag ctccccaaac aaaaagcata gctcattcat
     2281 tcccaagaac tgctgtgact aaggtctgca atccctggtg acaaggatct aggaaggtga
     2341 gcactgataa tctgcaatga gaacaaggtg actaccaggt aagggggcta caggagacaa
     2401 aggagtgcac tggaggcagg tgaggtgata aaagacaatg acagcagaag caattcccaa
     2461 ggggagacaa gccaaatagt gtgcattttc ctgaagctta aagtgccttt gtgtgatgaa
     2521 tgggtccagg ggagtctact cccttcctgt ctgtggaagc agcaggctga gtcaccatga
     2581 cagcctgcta attaaaatga cctcccggaa acgaggatta ggagataggg agagggaggg
     2641 aggctccagg gagatagggc cttctgcaca gtctttaaac agtctttgtg tttgagatgg
     2701 agattttcaa agtttattgc aaaagtcaag agcaaagctt gttttctctt tcacatactg
     2761 gttttcagaa atggtaacaa agaaccatat gttagttcgc tatgaatgtt ccattgtgta
     2821 catagcaacc ttcctgagtt tctattgccc aaataaagtg gtttgtgcag ct
//
