LOCUS       NM_001398853            2890 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus ArfGAP with GTPase domain, ankyrin repeat and PH
            domain 3 (Agap3), mRNA.
ACCESSION   NM_001398853 XM_006235942
VERSION     NM_001398853.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2890)
  AUTHORS   Hojgaard,K., Szollosi,B., Henningsen,K., Minami,N., Nakanishi,N.,
            Kaadt,E., Tamura,M., Morris,R.G.M., Takeuchi,T. and Elfving,B.
  TITLE     Novelty-induced memory consolidation is accompanied by increased
            Agap3 transcription: a cross-species study
  JOURNAL   Mol Brain 16 (1), 69 (2023)
   PUBMED   37749596
  REMARK    GeneRIF: Novelty-induced memory consolidation is accompanied by
            increased Agap3 transcription: a cross-species study.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2890)
  AUTHORS   Oku,Y. and Huganir,R.L.
  TITLE     AGAP3 and Arf6 regulate trafficking of AMPA receptors and synaptic
            plasticity
  JOURNAL   J Neurosci 33 (31), 12586-12598 (2013)
   PUBMED   23904596
REFERENCE   3  (bases 1 to 2890)
  AUTHORS   Qin,Q., Inatome,R., Hotta,A., Kojima,M., Yamamura,H., Hirai,H.,
            Yoshizawa,T., Tanaka,H., Fukami,K. and Yanagi,S.
  TITLE     A novel GTPase, CRAG, mediates promyelocytic leukemia
            protein-associated nuclear body formation and degradation of
            expanded polyglutamine protein
  JOURNAL   J Cell Biol 172 (4), 497-504 (2006)
   PUBMED   16461359
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Dec 27, 2021 this sequence version replaced XM_006235942.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KF447874.1, SRR26360186.261835.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMEA5760433 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-362               JAXUCZ010000004.1  11616924-11617285   c
            363-421             JAXUCZ010000004.1  11593417-11593475   c
            422-509             JAXUCZ010000004.1  11593083-11593170   c
            510-595             JAXUCZ010000004.1  11592769-11592854   c
            596-737             JAXUCZ010000004.1  11592549-11592690   c
            738-872             JAXUCZ010000004.1  11591891-11592025   c
            873-1000            JAXUCZ010000004.1  11591626-11591753   c
            1001-1159           JAXUCZ010000004.1  11589862-11590020   c
            1160-1252           JAXUCZ010000004.1  11586264-11586356   c
            1253-1357           JAXUCZ010000004.1  11581320-11581424   c
            1358-1529           JAXUCZ010000004.1  11576070-11576241   c
            1530-1684           JAXUCZ010000004.1  11569474-11569628   c
            1685-1775           JAXUCZ010000004.1  11569280-11569370   c
            1776-1998           JAXUCZ010000004.1  11568913-11569135   c
            1999-2254           JAXUCZ010000004.1  11567954-11568209   c
            2255-2890           JAXUCZ010000004.1  11567191-11567826   c
FEATURES             Location/Qualifiers
     source          1..2890
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q11"
     gene            1..2890
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /note="ArfGAP with GTPase domain, ankyrin repeat and PH
                     domain 3"
                     /db_xref="GeneID:362300"
                     /db_xref="RGD:1310751"
     exon            1..362
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..2461
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /note="centaurin, gamma 3"
                     /codon_start=1
                     /product="arf-GAP with GTPase, ANK repeat and PH
                     domain-containing protein 3"
                     /protein_id="NP_001385782.1"
                     /db_xref="GeneID:362300"
                     /db_xref="RGD:1310751"
                     /translation="MNFQAGGGQSPQQQQSLAAPGGGGSGGGGAGGGGQFGGAGPGAG
                     GGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLIERIEDLALQNQIR
                     EHVISIEDSFVNSQEWTLSRSVPELKVGIVGNLSSGKSALVHRYLTGTYVQEESPEGG
                     RFKKEIVVDGQSYLLLIRDEGGPPELQFAAWVDAVVFVFSLEDEISFQTVYNYFLRLC
                     SFRNASEVPMVLVGTQDAISAANPRVIDDSRARKLSTDLKRCTYYETCATYGLNVERV
                     FQDVAQKVVALRKKQQLAIGPCKSLPNSPSHSAVSAASIPAVHINQATNGGGSAFSDY
                     SSSVPSTPSISQRELRIETIAASSTPTPIRKQSKRRSNIFTSRKGADPDREKKAAECK
                     VDSIGSGRAIPIKQGILLKRSGKSLNKEWKKKYVTLCDNGLLTYHPSLHDYMQNIHGK
                     EIDLLRTTVKVPGKRLPRATPSTAPGTSPRGANGLALERSNTQLGGTTETEESFEFVV
                     VSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQSTALAVQTVR
                     TARGNSFCVDCEAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELL
                     AVMTAMGNALANSVWEGALDGYSKPGPEACREEKERWIRAKYEQKLFLAPLPSSDVPL
                     GQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQLLIW
                     YGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGEGCGLAPTPNREPANGTNPS
                     AELHRSPSIL"
     exon            363..421
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            422..509
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            510..595
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            596..737
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            738..872
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1000
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1159
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1252
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1357
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..1529
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1684
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1685..1775
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1776..1998
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            1999..2254
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
     exon            2255..2890
                     /gene="Agap3"
                     /gene_synonym="Centg3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgggcccgc tttgggcccc gcgcctccgg agccatgaac ttccaggcgg gcgggggcca
       61 gagtcctcag cagcagcaga gcctggcggc tccggggggc ggcggcagcg gcggcggcgg
      121 cgcggggggc ggcgggcagt tcggcggcgc ggggcccgga gccgggggtg gcggcccctc
      181 gcagcagctg gccggcgggc ccccccagca gtttgcgctc tccaactcgg ccgctatccg
      241 ggccgagatc cagcgcttcg agtcggtaca ccccaacatc tacgccatct acgacctgat
      301 cgagcgaatc gaggatttgg cactgcagaa tcagatccgg gagcacgtca tctccatcga
      361 ggactcattt gtgaacagcc aggagtggac cctgagccgc tctgtgccgg agcttaaagt
      421 gggcatagtg gggaacctgt ctagtgggaa atccgccttg gttcaccggt atctgacagg
      481 gacctacgtc caggaagaat cccctgaagg gggtcggttt aaaaaggaga ttgtggtgga
      541 tggccagagt tacctgctgc tgatccgaga tgaaggaggc ccccctgagc tccagtttgc
      601 tgcctgggtg gatgcggtgg tgtttgtgtt cagcctggag gatgaaatca gcttccagac
      661 agtgtacaac tacttcctgc gcctctgcag cttccggaat gccagcgagg tgcccatggt
      721 gctggtgggc acgcaggatg ctatcagtgc tgccaatccc cgggtcattg atgacagcag
      781 ggcccgcaag ctgtccacag acctgaagcg ctgtacctac tatgagacat gcgcaaccta
      841 tgggctcaat gtggagcgag tcttccagga cgtggcccag aaagtggtag ccttgcggaa
      901 gaagcagcag ctggccatcg ggccctgcaa gtccctgccc aactcaccca gccactcggc
      961 cgtgtctgct gcctccatcc cagctgtgca catcaatcag gccacgaacg gcggcggcag
     1021 cgccttcagc gactactcct cctcagtccc ctccacccct agcatcagtc agcgggagct
     1081 gcgcatcgag accatcgctg cctcttccac ccccacaccc atccgcaagc agtccaagcg
     1141 gcgctctaac atcttcacgt ctcgaaaagg tgctgacccg gacagggaga agaaagctgc
     1201 ggagtgtaaa gtggacagca ttgggagcgg ccgggccatc cctatcaagc aggggatcct
     1261 gctgaaaagg agcggcaaat ccttgaacaa ggagtggaaa aagaagtatg tgacactgtg
     1321 tgacaacggg ctgcttactt accaccccag cctgcacgat tacatgcaga acatccacgg
     1381 caaagagatc gacctcctgc ggaccacagt caaagtgcca gggaagcgcc tgccccgagc
     1441 cactccctcc acagctccgg gcaccagtcc ccgtggtgcc aacgggttgg ccctggagcg
     1501 gagtaacaca cagctgggtg gtaccacaga gacagaggag tcctttgaat ttgtggtggt
     1561 gtccctcact ggtcagacct ggcacttcga ggcctcaaca gcggaagagc gggagctgtg
     1621 ggtgcagagc gtacaggccc aaatcctcgc cagcctccag ggatgtcgca gcgccaagga
     1681 caagacccgg ctggggaacc agagcacagc cctggctgtg cagactgtcc gcacagcccg
     1741 tggcaatagc ttctgtgttg actgcgaagc tcccaatcca gactgggcca gcctgaatct
     1801 gggtgccctg atgtgtatcg agtgttcagg gatccaccga cacctgggag ctcacctgtc
     1861 ccgagtccgc tccctggacc ttgatgactg gccacccgaa ctgctagctg tcatgaccgc
     1921 aatgggcaat gccttggcta acagtgtctg ggagggggct ctggatggct actcgaagcc
     1981 aggcccagaa gcctgcagag aggagaagga acgctggatc cgggccaagt atgaacagaa
     2041 gctcttcctg gccccactgc cgagctcgga tgtgcctctg gggcagcagt tactccgggc
     2101 cgtggtggag gatgacctac gactgctggt gatgctgctg gcccatgggt ccaaggagga
     2161 ggtgaacgag acctacgggg atggcgatgg caggacagcc ctgcacctgt ccagtgccat
     2221 ggccaacgtc gttttcacac agctgctcat ctggtacggg gtggacgtga ggagccgtga
     2281 tgcccgaggc ctgaccccac tggcctatgc ccgccgtgcc ggcagccagg agtgtgcaga
     2341 catcttgatc cagcatgggt gccccgggga gggctgtggg ttagcaccca ctcccaacag
     2401 agagcctgcc aacggcacca acccttctgc agaactgcac cgcagcccta gtatcctatg
     2461 aagctcagga agaggccaga gggaccagaa ggactccaca gcctggaggg gacatggcga
     2521 agcaggggtg cagagaagag gggtgacgag ggcgcaggga tgaagaggtc tgtgattaag
     2581 ctgcagcaga gcagggtctg tcattcagcc ctctgccctg tggtgccatt aaaggacaga
     2641 accctttgga ggtgcctgtg aggagagggg ggcaggacct ctccctcctc cagaaccctg
     2701 cctcctcagg acacctccca cagtcctccc tgcagtggac agggacacag gacataagat
     2761 ggggtaccag atgaaagaaa gacaaggggc cgatctgtga gtcccatgta aaacttgtac
     2821 attggaatat ttatgttcgt gtatatacgt ggtgtgtgag ccaataaacc aggctgtatg
     2881 tgtggcccca
//
