LOCUS       NM_001037656            2045 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus AFG1 like ATPase (Afg1l), mRNA.
ACCESSION   NM_001037656 XM_577959
VERSION     NM_001037656.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2045)
  AUTHORS   Cesnekova,J., Spacilova,J., Hansikova,H., Houstek,J., Zeman,J. and
            Stiburek,L.
  TITLE     LACE1 interacts with p53 and mediates its mitochondrial
            translocation and apoptosis
  JOURNAL   Oncotarget 7 (30), 47687-47698 (2016)
   PUBMED   27323408
REFERENCE   2  (bases 1 to 2045)
  AUTHORS   Cesnekova,J., Rodinova,M., Hansikova,H., Houstek,J., Zeman,J. and
            Stiburek,L.
  TITLE     The mammalian homologue of yeast Afg1 ATPase (lactation elevated 1)
            mediates degradation of nuclear-encoded complex IV subunits
  JOURNAL   Biochem J 473 (6), 797-804 (2016)
   PUBMED   26759378
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC107937.1.
            
            On Dec 9, 2005 this sequence version replaced XM_577959.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107937.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2045
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q13"
     gene            1..2045
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /note="AFG1 like ATPase"
                     /db_xref="GeneID:502479"
                     /db_xref="RGD:1561501"
     exon            1..233
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..1537
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /note="lactation elevated protein 1; lactation elevated 1"
                     /codon_start=1
                     /product="AFG1-like ATPase"
                     /protein_id="NP_001032745.1"
                     /db_xref="GeneID:502479"
                     /db_xref="RGD:1561501"
                     /translation="MAASWSPLVTLRSAARSRLTGRGVGCGARVIAIFPPAPGPRKPL
                     WKAYTVQTLEGVRPTAASEAHSRALAVCHGPLAHYDFLIKAQELKNDEHQRRVVQCLQ
                     KLQEDLKGYNIEEGGLFSKLFSRNKPPKGLYVYGDVGTGKTMVMDMFYEYVEVKSKRR
                     VHFHGFMLDVHKRIHRLKQSLPKRKVGFMAKSYDPIAPIAEEISQEASLLCFDEFQVT
                     DIADAMILKQLFENLFKNGVVVVATSNRPPEDLYKNGLQRANFVPFIAVLKEYCNTVQ
                     LDSGVDYRKRELTPAGKLYYLTSEADVGTVMDKLFDELAQKQNDLTSPRILKVQGREL
                     RLNKACGTVADCTFEELCERPLGASDYLELSKNFDTVIIRNIPQFSLAKRTQVRRFIT
                     LIDNFYDFKVRIICSASVPISSLFVYQHQDSESDQSRVLMDDLGLSQDSAGLSMFTGE
                     EEIFSFQRTLSRLTEMQTEQYWIEGDRSRK"
     exon            234..457
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            458..509
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            510..611
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            612..742
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            743..842
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            843..901
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            902..984
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1055
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1156
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1297
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1411
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
     exon            1412..2020
                     /gene="Afg1l"
                     /gene_synonym="Lace1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctcaggcgt ggccttctgg agcgccacgg cattcagctg ttccgtcgtg tcttcgtgtt
       61 acaataaagt tttcctccct gtacggagct caagatggcg gcctcctggt cgcccttggt
      121 taccctgcgc tccgcggcgc gtagccggct gactgggaga ggtgttgggt gcggggcgcg
      181 ggtcatcgca atctttcctc cggcccctgg ccctaggaaa cccctttgga aagcctacac
      241 agtccagaca ttggagggtg tgcgcccaac agccgcttcc gaggcccatt cgagagcttt
      301 ggctgtttgc cacgggcctc tggcccacta cgactttctg atcaaagctc aggagctgaa
      361 gaacgatgaa catcaaagaa gagtcgttca gtgtttgcag aagttacagg aggaccttaa
      421 aggatacaac atagaggaag gagggctctt ttcaaagctc ttttcaagga acaaacctcc
      481 aaagggcctg tatgtttatg gagacgttgg tacggggaaa acaatggtga tggacatgtt
      541 ttatgagtat gtggaagtga agagcaaaag gcgggtccat tttcacggct tcatgctaga
      601 tgtgcacaaa aggatacacc gccttaaaca gagtttgccg aaaaggaagg tgggattcat
      661 ggctaagtcg tacgacccga tagcgcccat agcggaggaa atcagccaag aggctagtct
      721 cctgtgtttt gatgaatttc aggtcactga catcgctgac gccatgattc tgaaacagct
      781 ttttgaaaat ctgttcaaaa acggggtcgt cgttgtggca acgtccaaca gaccaccgga
      841 agatctctat aaaaacggac tccagagggc taactttgtg ccatttatag ctgtcctgaa
      901 ggaatattgc aatacggtcc agctggattc tggggtagat tatcggaaaa gggaactcac
      961 ccctgccggg aaactctact acctcacaag cgaggctgat gtggggactg tcatggataa
     1021 gttgtttgat gagctggctc agaaacaaaa cgatctaact agcccaagga ttctgaaagt
     1081 gcaaggcaga gagctgcggc tgaataaagc ctgtggaacc gtcgccgact gcacgtttga
     1141 ggagctgtgt gagagaccac tcggagcaag tgactatttg gaattatcca agaattttga
     1201 tacggtaatc atacggaaca ttccacagtt ttctctggca aagaggacgc aagtgcgcag
     1261 attcatcact ctcattgaca acttctacga cttcaaggtg cgtatcatct gcagcgcctc
     1321 ggtccccatc tccagcctgt ttgtgtatca gcatcaggac agcgagtcgg accaaagtcg
     1381 ggtgctgatg gatgacttgg ggctgagcca ggactcagcg ggactctcca tgtttaccgg
     1441 ggaggaggaa atcttctcct ttcaacgcac tctttcccgc ctcacagaga tgcagaccga
     1501 gcagtactgg attgaagggg acagaagcag gaagtaactg tcaccttcac aactaataat
     1561 aaaaatgtga ccgggtaaag ctgcgagaca gcgagacatc actacgtcac tatgagacgt
     1621 gacaggatct ttttcctcct cgtcaatgca ctttgccctc tgggctgctg cctctgaggc
     1681 agtggacggg cacactgaag atgtctcttc tttgtagatc cacatttgtt ttgatttatt
     1741 tctgcatcat aaagtggaat catcactctt gaagatcact gcaaaaccca acatgtcggc
     1801 aactgacttc atcatgaacg tacaaacggg cagagagtgc aggacgtctg tgcatctcca
     1861 agctttggct gcacagaagt caccttagaa acacattcgc tataagaagc aggcagagtc
     1921 actccccgtc cttgatcctg agtcgcagag ttgggcctcg taggaaactg gaaaggacat
     1981 ttgacaaatc ttctgtaaat aaaagctgac ttctcctcca aaaaaaaaaa aaaaaaaaaa
     2041 aaaaa
//
