LOCUS       NM_001107206            4660 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus ALF transcription elongation factor 1 (Aff1),
            mRNA.
ACCESSION   NM_001107206 XM_001065599 XM_223161
VERSION     NM_001107206.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4660)
  AUTHORS   Luo,Z., Lin,C. and Shilatifard,A.
  TITLE     The super elongation complex (SEC) family in transcriptional
            control
  JOURNAL   Nat Rev Mol Cell Biol 13 (9), 543-547 (2012)
   PUBMED   22895430
  REMARK    Review article
REFERENCE   2  (bases 1 to 4660)
  AUTHORS   Smith,E.R., Lin,C., Garrett,A.S., Thornton,J., Mohaghegh,N., Hu,D.,
            Jackson,J., Saraf,A., Swanson,S.K., Seidel,C., Florens,L.,
            Washburn,M.P., Eissenberg,J.C. and Shilatifard,A.
  TITLE     The little elongation complex regulates small nuclear RNA
            transcription
  JOURNAL   Mol Cell 44 (6), 954-965 (2011)
   PUBMED   22195968
REFERENCE   3  (bases 1 to 4660)
  AUTHORS   Baskaran,K., Erfurth,F., Taborn,G., Copeland,N.G., Gilbert,D.J.,
            Jenkins,N.A., Iannaccone,P.M. and Domer,P.H.
  TITLE     Cloning and developmental expression of the murine homolog of the
            acute leukemia proto-oncogene AF4
  JOURNAL   Oncogene 15 (16), 1967-1978 (1997)
   PUBMED   9365243
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474022.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_223161.4, XM_001065599.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760389, SAMEA5760494
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..4660
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..4660
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /note="ALF transcription elongation factor 1"
                     /db_xref="GeneID:305152"
                     /db_xref="RGD:1307940"
     exon            1..176
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     CDS             133..3645
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /note="myeloid/lymphoid or mixed-lineage leukemia
                     (trithorax homolog, Drosophila); translocated to, 2;
                     AF4/FMR2 family, member 1"
                     /codon_start=1
                     /product="AF4/FMR2 family member 1"
                     /protein_id="NP_001100676.1"
                     /db_xref="GeneID:305152"
                     /db_xref="RGD:1307940"
                     /translation="METKIRPGERGKFACLYNEDRNLLRIREKERRNQEAHQEKEAFP
                     EKAPLFAEPYKTAKGDELSSRIQTMLGDYEEMKEFLSSKSHPHRLDGSEDRPGKPRYP
                     SCHDRGSGASGSFRTHVYHQPTHTSAPGSLSVSNVSQSPKMAQPRMEPVPSLHAKIYG
                     APDGPRPAQDRLSQGHCSRKCDRRAEGDSERKLSPFISSLPSPVPPLSPAHSRPQATS
                     KAHGSGTGTQSCYASKPSKDPVVTAQEKETPLDSLVAVTSLGAAPPQPPCQTFPPPPL
                     PSKSIAMQQKPTAYVRPMDGQDQAPSESPELKPPLEDFGQQSFEKPDLKVPAKAKLTR
                     LRMPSQTVEQPYSNEVHCVEEILKEMTHSWPSPLTAIHTPSTAEPSRFPFPTKDPLHI
                     SSATQSQKQYDAPSKTHPNPQQGTSMLEDDLQLSDSEESDVEQAVEKPPSPPAPPSAP
                     QTIPEPVASAHSSSAESESSESDSSSDSESESSSSDSEENEPLETQAPEPEPPTTNKW
                     QLDNWLTKVNQPSVPLESRGSTESPRCRQESKGGGEGSSDQQHPDSKDPPLKSSSKAL
                     RGPSEGPQPGKRNCPKSPAQQETPPPRQTVGSKQPRKPTKGSTQAEQPQASSRVEGEA
                     GPVAYGSKEQTSKDKPKVKTKGRPRAVGSREPKSEVPVPVPQAAVPKPQPPAPTPIEK
                     RKHKSSTAPSKALSGPQPTKDSAGDRNQEHPALVSLTQSQGQPNSGRGSGGGRTSGCR
                     QAVITQEDSCRDKLLLPLRDTKLLSPLRDSPPPTSLVVKITLDLLTRVPQPPGKGGRP
                     RKSEHKQLPAGKKQDLEARGCDSSSRVTKKRKAEPEKEHSHKRLRLDKSQTSSSSSSH
                     AESSKSKTPRPSSECSRKEMLPPPPVVPSSSSSSSSSQKPSKPAHKRPRPDADIGSQD
                     PPRSSGSTKSSCTDSSVPKHRKVQARDSEHKGSSGDAANPFPVPSLPNGNSKPGKPQV
                     KSDRQQADFHMKEAKKLKCKAEAMVDKAGKAFKYLEAVLSFIECGMATESESSAKSAY
                     TVYSETVDLIKFVMSLKSFSDNTVPAQEKIFAVLCLRCQSLLNMAMFRCKKDTVMKYS
                     RTLSEHFRSTSKVAQAPSPCVARQVHRRSVPRLPNAFSCQLCWIPDECWQQYGGHGGD
                     GHRQHPGHHPEHDLLLCHHHIPCP"
     exon            177..297
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            298..1161
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1206
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1293
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1330
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1382
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1383..1437
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..1475
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1629
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..2622
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            2623..2720
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            2721..2967
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            2968..3059
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            3060..3120
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            3121..3254
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            3255..3326
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            3327..3471
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            3472..3695
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
     exon            3696..4660
                     /gene="Aff1"
                     /gene_synonym="Mllt2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttattttcg ggaagtgaag ttggtttctc gggtctgccg gagcctggat tttcattggc
       61 gtgccctgtg cactctcatc cggctctcct agttggccat ttggcgtcgt cagaagtttg
      121 gaagcgcact taatggaaac taaaattcgc cctggagaga gagggaaatt tgcctgcttg
      181 tacaatgaag acagaaacct gcttcgaatc agagagaagg aaaggcgcaa ccaagaggcc
      241 caccaggaga aagaggcgtt tcctgagaag gctccactgt ttgcagagcc ctacaagacc
      301 gcgaaaggcg atgagctgtc gagtcgcata cagaccatgc taggtgacta tgaagagatg
      361 aaggagttcc taagcagcaa gtcccaccct caccgcctgg acggctctga ggacaggccg
      421 gggaagccca gatacccctc gtgtcacgac cgggggagcg gtgcatccgg ctccttccgc
      481 acacatgtct accaccagcc tacccacact tctgctcccg gatcactttc tgtcagcaac
      541 gtcagccaaa gtccaaagat ggcacagccc aggatggagc cggtgccaag tctccatgcc
      601 aaaatctacg gagcgcccga tggcccccgt ccggctcaag atcgcctcag tcaggggcat
      661 tgttccagaa agtgtgaccg aagagccgag ggagactcgg agaggaagct ctcgcccttc
      721 atctcctcct tgccgtcccc cgtgccccca ctctcacctg cacattccag gccgcaggca
      781 accagcaagg ctcacggcag cggaactggc actcagagct gctatgcctc caagccttcc
      841 aaggacccgg tggtgacggc ccaagagaag gagactcctc tcgacagtct ggtggcagtt
      901 accagccttg gagcagcccc tcctcagcca ccttgccaaa catttccacc acctcccctc
      961 ccctcaaaaa gcatcgcaat gcagcagaag cccacagcgt acgtccgtcc catggacggt
     1021 caggaccagg ctcctagcga gtcccctgag ctgaagccgc cgctggagga ctttggtcag
     1081 caaagctttg agaaaccgga ccttaaagtg cctgccaaag ccaagctcac tagactaagg
     1141 atgccctcgc agacggtaga gcagccgtac tccaatgaag tccactgtgt tgaagagatt
     1201 ctgaaggaaa tgacccactc gtggccgtct cctctgactg ccatacacac acccagtaca
     1261 gccgagccgt ccagatttcc tttccctaca aaggatcctc tgcacatcag ttctgcaacc
     1321 caaagccaaa aacaatacga tgcaccttca aaaacccacc ccaaccccca gcaaggaaca
     1381 tccatgctcg aggatgacct gcagctcagt gacagtgagg aaagcgacgt ggagcaagcc
     1441 gtggagaagc ctccgtcccc acctgcacct ccaagtgctc cgcagacgat tcccgagccc
     1501 gtggcctcag cacattccag tagtgcagag tcagagagca gcgagtcaga cagttcctcc
     1561 gactctgaga gcgagagcag ctccagcgac agtgaggaga acgagcccct ggaaacacag
     1621 gctcccgagc ctgagcctcc gacaacaaac aaatggcagc tggacaactg gttgaccaaa
     1681 gtcaaccaac catcagtgcc cctagagagc cgggggagca cagagtctcc acgatgtcgc
     1741 caggaaagta agggtggtgg tgagggcagc agtgaccagc agcatcctga ttccaaagac
     1801 cctcccctga agagttccag caaagctctc cggggtccct ctgaggggcc gcagcctggg
     1861 aagaggaact gtccgaagtc ccctgctcaa caggaaaccc ccccacctcg gcaaactgtg
     1921 ggcagtaaac aacccagaaa acccaccaag ggctccaccc aggcagagca gccccaggcc
     1981 agctctcgag tggagggcga agcaggaccc gtagcctatg gctcaaagga gcagacatcc
     2041 aaagacaaac ccaaggtgaa gacgaaaggc aggccccgtg ctgtgggcag tcgggagccc
     2101 aaatctgagg tccccgtacc tgtgcctcag gcagctgtgc ccaagccgca gccacctgcg
     2161 cccaccccca tcgagaagag gaaacataag agttccacag ccccctccaa ggcactctca
     2221 ggccctcagc caaccaagga cagtgctggg gacaggaacc aggagcaccc tgcccttgtc
     2281 tccttgactc agagccaggg tcaacccaac agcggcaggg gcagcggtgg tggcaggact
     2341 agtggttgcc ggcaggccgt gatcacccag gaggacagct gtagagacaa gctcctgttg
     2401 cctttgagag acaccaaact gctctcgccg ctcagggact ctccaccacc gacaagcttg
     2461 gtggtgaaga taaccttaga ccttctcacg agggttccgc agccaccggg gaaggggggc
     2521 cgccccagga agtcagagca caagcagctg ccagcaggga agaagcagga cttggaggca
     2581 aggggctgtg acagttccag ccgagtcacc aagaagagaa aggctgaacc ggagaaagag
     2641 cacagtcaca agaggctccg actggataag tcgcagacgt cctcatcctc gtcttcccac
     2701 gcagagtctt ccaagtcaaa gacacccagg ccctcctcag agtgctcaag aaaggaaatg
     2761 cttcctcctc cgccggtggt gccctcatcc tcgtcgtctt cctcgtcttc ccagaagcca
     2821 agcaaacctg cacacaagag gcccaggcca gatgcagaca tcggtagcca ggaccctccc
     2881 agaagttctg gcagcacgaa gagcagctgt acagactctt cagttccgaa gcacagaaaa
     2941 gtacaggccc gggactctga acacaaagga tcttctggag atgctgcgaa tccttttcca
     3001 gtgccttctt tgccaaatgg taactctaag ccaggaaagc cacaggtgaa atctgacaga
     3061 caacaagctg actttcacat gaaggaggct aaaaagctga agtgcaaggc ggaggcaatg
     3121 gtggacaagg ctggaaaagc cttcaagtat ttggaagccg tcctgtcttt tattgagtgt
     3181 ggaatggcca ccgagtcaga gagttcagcg aagtcagcgt acaccgtgta ctcagaaacc
     3241 gtagacctca ttaagttcgt gatgtcgctt aaatccttct cagataacac agtgccagca
     3301 caagagaaga tatttgctgt cttatgcttg cgttgccagt cccttttgaa catggcgatg
     3361 ttccgatgta aaaaggacac ggtgatgaag tattcccgta cccttagcga gcacttcagg
     3421 agtacctcca aagtggccca ggcaccttct ccatgcgtgg caaggcaagt tcacaggcgt
     3481 tccgtccccc gtctccccaa tgccttctcc tgccagctct gctggatccc agacgagtgc
     3541 tggcagcagt atgggggcca tgggggcgac ggccaccgtc agcaccccgg tcaccatcca
     3601 gaacatgacc tcctcttatg tcaccatcac atcccatgtc cttaaggcct ttaccctttg
     3661 ggaacaggca gaggccctca caaggaagaa caaagaattc tttgctcagc tcagcacaaa
     3721 agtgcgcgtg ttggccctca acagcagcct ggtggacctg gtgcactaca caaggcaggg
     3781 cctccagcgg ctgagacaag caccccaaac cccgctaatg taggctgggc ctactcgatg
     3841 ccttgtgcct ctctgcacag ttggaagccg tgatccactg tagacaattg tcagatgggg
     3901 atgtcagtac tcgagaagag gagcgccgtg aggccgtgag acgaccagga tgctcgacca
     3961 cttcaactca caggagctgt gtggtcattg gccggacact ggtcagctca gcagttgctg
     4021 gaaaatgatc ttgcctttcc aaagggaagg acacaagtgc aatggagtcc agctggcgta
     4081 cgaattggtc cagaaacatt tctgggtttt gttttttttt tctgtttgtc tgaacaagag
     4141 gataaaaatt gcaaacaaga ggaagagaac gtctcagaag ccacccttgt tcacttccgg
     4201 aaggagtttt tttttttttt tccggagctg gggaccgaac ccagggcctt gcgctcccta
     4261 ggcaagcgct tttttttttt ttaataataa tttttggtga agggctttat gattttgttc
     4321 tcttctcaag ttttaaagga aacgttgctt aatacattct aatggccatc tgtggaacac
     4381 aagttgcgga ggactccacc gcacctcact tcctgcaggg aaggggctct gatgaccgag
     4441 tactgtcatt tacaaaatct aaggtgacac ccaccgtacc ccagtgccta gagtgctgca
     4501 cattgtctag ctcaggcctc tctggctata ctgagaagca tcccccgtcg gccctagagg
     4561 agtggaagca gttacatccg ggttctttct cacagtcttc ctcacatccc cagaggcctc
     4621 actcttcctc ctgccgcact ccacgaaaaa ccttgggcaa
//
