LOCUS       NM_001401545            7236 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus AE binding protein 2 (Aebp2), mRNA.
ACCESSION   NM_001401545
VERSION     NM_001401545.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7236)
  AUTHORS   Ragazzini,R., Perez-Palacios,R., Baymaz,I.H., Diop,S., Ancelin,K.,
            Zielinski,D., Michaud,A., Givelet,M., Borsos,M., Aflaki,S.,
            Legoix,P., Jansen,P.W.T.C., Servant,N., Torres-Padilla,M.E.,
            Bourc'his,D., Fouchet,P., Vermeulen,M. and Margueron,R.
  TITLE     EZHIP constrains Polycomb Repressive Complex 2 activity in germ
            cells
  JOURNAL   Nat Commun 10 (1), 3858 (2019)
   PUBMED   31451685
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7236)
  AUTHORS   Herz,H.M., Garruss,A. and Shilatifard,A.
  TITLE     SET for life: biochemical activities and biological functions of
            SET domain-containing proteins
  JOURNAL   Trends Biochem Sci 38 (12), 621-639 (2013)
   PUBMED   24148750
  REMARK    Review article
REFERENCE   3  (bases 1 to 7236)
  AUTHORS   Pasini,D., Cloos,P.A., Walfridsson,J., Olsson,L., Bukowski,J.P.,
            Johansen,J.V., Bak,M., Tommerup,N., Rappsilber,J. and Helin,K.
  TITLE     JARID2 regulates binding of the Polycomb repressive complex 2 to
            target genes in ES cells
  JOURNAL   Nature 464 (7286), 306-310 (2010)
   PUBMED   20075857
REFERENCE   4  (bases 1 to 7236)
  AUTHORS   Shen,X., Kim,W., Fujiwara,Y., Simon,M.D., Liu,Y., Mysliwiec,M.R.,
            Yuan,G.C., Lee,Y. and Orkin,S.H.
  TITLE     Jumonji modulates polycomb activity and self-renewal versus
            differentiation of stem cells
  JOURNAL   Cell 139 (7), 1303-1314 (2009)
   PUBMED   20064376
REFERENCE   5  (bases 1 to 7236)
  AUTHORS   Peng,J.C., Valouev,A., Swigut,T., Zhang,J., Zhao,Y., Sidow,A. and
            Wysocka,J.
  TITLE     Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and
            target gene occupancy in pluripotent cells
  JOURNAL   Cell 139 (7), 1290-1302 (2009)
   PUBMED   20064375
REFERENCE   6  (bases 1 to 7236)
  AUTHORS   He,G.P., Kim,S. and Ro,H.S.
  TITLE     Cloning and characterization of a novel zinc finger transcriptional
            repressor. A direct role of the zinc finger motif in repression
  JOURNAL   J Biol Chem 274 (21), 14678-14684 (1999)
   PUBMED   10329662
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.18341.1,
                                           SRR22582424.1431195.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-829               JAXUCZ010000004.1  175259544-175260372
            830-1037            JAXUCZ010000004.1  175271159-175271366
            1038-1145           JAXUCZ010000004.1  175276433-175276540
            1146-1332           JAXUCZ010000004.1  175280824-175281010
            1333-1457           JAXUCZ010000004.1  175283904-175284028
            1458-1525           JAXUCZ010000004.1  175287973-175288040
            1526-1639           JAXUCZ010000004.1  175289093-175289206
            1640-7236           JAXUCZ010000004.1  175291553-175297149
FEATURES             Location/Qualifiers
     source          1..7236
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q44"
     gene            1..7236
                     /gene="Aebp2"
                     /note="AE binding protein 2"
                     /db_xref="GeneID:297705"
                     /db_xref="RGD:1307233"
     exon            1..829
                     /gene="Aebp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..1670
                     /gene="Aebp2"
                     /codon_start=1
                     /product="zinc finger protein AEBP2"
                     /protein_id="NP_001388474.1"
                     /db_xref="GeneID:297705"
                     /db_xref="RGD:1307233"
                     /translation="MAAALTDMADLEELSRLSPLSPGSPGPAARGRAEPPEEEEEEED
                     DEAEAEAVAALLLNGGAGGGAGGGEAETMSEPSPESASQAGGDEDEDDEDDEDEGSSS
                     GGAEEESSAESLVGSSSGGCSGDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGGPGG
                     PGNGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSIS
                     STLMDIDSTISSGRSTPAMMNGQGSTAASSKHIAYNCCWDQCQACFNSSPDLADHIRS
                     IHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQ
                     GGLARHVPTHFSQQNSSKVSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDA
                     QTLDAIRHRAICFNLSAHIESLGKGHSVVFHSTVIAKRKEESGKIKLLLHWMPEDILP
                     DVWVNESERHQLRTKVVHLSKLPKDTALLLDPNIYRTMPQKRLKR"
     exon            830..1037
                     /gene="Aebp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1145
                     /gene="Aebp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..1332
                     /gene="Aebp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1457
                     /gene="Aebp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1525
                     /gene="Aebp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1526..1639
                     /gene="Aebp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1640..7236
                     /gene="Aebp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgtccccgc gcgggctccg tagcgcgtgt gcagcctgac gcagccccgc gggccctcct
       61 cccgctctgc ggcggctgcg aggagtttgg ggcgtgcggg cgcggggagg cgggggcgag
      121 gcggcgcgcc gcgagaggag gcggcggcgg cgagaggagg cggaggagca gcaggcgccg
      181 ccatggccgc cgcgctcacc gacatggccg acttggagga gctctcccgc ctcagcccgc
      241 tgtcccccgg cagccccggg cccgcggcgc gcggccgggc cgagccgccg gaggaagagg
      301 aggaggagga ggacgatgag gcggaggcag aggcggtggc cgcgctgctg ttgaacggcg
      361 gagcgggcgg cggcgcgggg ggcggcgagg cggagaccat gtcggagcct agccccgaga
      421 gcgccagcca ggcgggcggg gacgaggacg aggacgacga ggacgacgag gacgagggca
      481 gtagcagcgg cggcgctgag gaggagagca gcgccgagag cctggtgggc agcagcagcg
      541 gcggctgcag cggcgacgag acgcgctcgc tgagcccggg cgcggcgagc agcagcagcg
      601 gcgatgggga cgggaaggag ggcctggagg agcccaaggg accgcggggc ggcccgggcg
      661 gcccgggcaa cggcggcggt agtagcagca gtagcgtggt gtcgagcggc ggcgacgagg
      721 gttacggcac cgggggaggc gggagcagcg cgacctccgg gggccggcgg ggcagcctgg
      781 agatgtcgtc ggacggggag ccgctgagcc gcatggactc ggaggacagc atcagcagca
      841 ctctaatgga catagacagc acaatctcca gtggacgctc aactccagcc atgatgaatg
      901 gacaggggag cactgctgct tccagcaagc acattgccta caactgctgt tgggaccagt
      961 gccaggcctg cttcaactcc agcccagacc tggcagacca cattcgctcc atacatgtag
     1021 atggtcagcg tggaggggtg ttcgtttgct tgtggaaagg ctgtaaggtg tataacaccc
     1081 catcaaccag tcagagctgg ctacagcggc acatgctgac acacagtgga gacaaacctt
     1141 tcaagtgtgt agttggtggc tgcaatgcca gctttgcttc tcagggaggg ctagctcgcc
     1201 atgtacccac acacttcagt cagcagaact cctcaaaagt ttctagccag ccaaaggcca
     1261 aagaagaatc tccttctaaa gctggaatga acaagaggag gaaactgaag aacaagagac
     1321 ggcgctcgtt accgcgacca catgatttct tcgatgcaca aacactggat gccataagac
     1381 atcgagccat atgctttaac ctctcggctc atatagaaag tttagggaag ggacacagtg
     1441 ttgtttttca tagtactgta atagctaaga gaaaggagga atctgggaag ataaagcttt
     1501 tgcttcattg gatgcccgaa gacattctgc cagatgtatg ggtgaatgaa agtgagcgac
     1561 atcagttaag aactaaagta gttcatttat caaaactacc caaagacact gccttgctgc
     1621 tggacccaaa catctacaga acaatgccac agaagaggtt gaagaggtaa aacattcata
     1681 aatacataaa agcaaacaag cggggaacct gcagtcttag tcactgacaa tgggttaggg
     1741 aaagttgcac attacagtca accccgtcct cttttacttt taagcccagt atttagagta
     1801 atatttatgc ctagtgtgga ccttctgtga ctggagtaga tcctgtgtgg agcatattaa
     1861 tatgcctgta gcccacatgg ctgtgggaca ctgcgcagac acttgctggc acctcagtgg
     1921 aacagcttct gaaaggaagg aaggaaggaa ggaaggaagg ctttgcatgc tcgctgccta
     1981 ggctgctgat ttctccccta gtgactgtag cagcagtcgt atttggaaag acaagcaatt
     2041 gcccttaaat accaaagcac tgtgagataa ccatcttgac agtgtgagtt gatttgaagt
     2101 cctaagggaa aatatttaga cagtggaaat tatcaagaga taattaacct ttcagttatg
     2161 ataaatagat gtgattggtt gccatttgtg ttcttttgca gaactctgat aagaaaaatg
     2221 ttcaatttgt atttaagcaa acagtgaacg acgtttgcaa tcaactaaaa attcgtctat
     2281 cgagttaggt ctgagaattg ctataaagag tgtggccgta tgtctgatgg ctcccttttc
     2341 aggactaggg tctcacgggg cacagtgtgt taatatttac ctaaataact cttgtcaatg
     2401 gtttttgaaa aaaacctcgg tttcaaaata tttgaatgat ctccatattt tcatttaacc
     2461 tctgactctt taaatttttt tcctgaggaa agtgttttga gttttttaac gttaaaaaaa
     2521 ttgtattttt tttaaaatat cttcaaactg aatcttttat gcaccaaagt tggttttgaa
     2581 aaggaaaata aaatcacttt cttgcttggc aggcaagaag ccatatggaa tttttttaac
     2641 ttttacagaa atgtgtaact tgtcagtact gtatcaaaca aatgttgcat agagataata
     2701 gagcgttgct tgtaaataat tcagcagatt tgtaatatat ttttctatta tgaaatgtac
     2761 tgtagatgtt ttctagaggc atgaaagtca atgtatatat tatggtagaa ataatattga
     2821 aggaaattgt aactcactag tgctgccaga gggattgcta acaaagcacc tttaacgaga
     2881 gatgtctgtg cagactgaag ggactgtgta ctactgttaa tgtctaagaa caaagcattg
     2941 ggcatcattc cagaaagtcc agggaggacc ctgacctgta atagtttacg gcaccccctc
     3001 tgacagaggc tgaggcagtc gttcctcact gttggagcag cactgtagca tgtgctgtgc
     3061 agtcagactg cagaaaccgc tcctcacttg gagttctcgc ttcctacagt gtcaggaata
     3121 ccagcagttt ttactctaag tttttaaaga atagacaata taaaattaat cctttagttc
     3181 caaaatggga aacgttccat gatgcataga tcatttctca tttgcttaaa aaatgaaaga
     3241 ccacccacag ggtcttaaaa gaatgggagg ctgaaatggt gggggttgaa gaggtagata
     3301 aggagcagtc ccagagcctg agggagcctg agggacgagg gacagcactg caggtgaggc
     3361 actctgggac agccatctaa gatgctaaga tgtagaaaat gggggtctgt tttcagagga
     3421 aaagcagtgt gctttactat ttccttttgc ttaagcactt catcatttgt tttattctgt
     3481 atctgcgaag gactctgcaa ctcctttgtt cctttaaaat tttggtttgt taaaatattg
     3541 ccaaatagag tgtttgagac atagtttgta cctgcatttt tattttactg tctcatgttc
     3601 ttgtacatca ttcctaattg accgatgatt gtagactttg cttgagtatt ttttctaata
     3661 aaacaaagca aattacactt agcttcaaat tgtaacaatt caatttaact ttaaggtgac
     3721 atctggaagt atacattgaa cattttcttt agatgcatag agaacaaata agttactatt
     3781 atgtatagaa tttttgctgt caaaaccata atgctagtta ctgactagcc tctgagtacg
     3841 caggtattca cggtcccttt gcttctgatt gactgggctt gacacttgtt agcacaccaa
     3901 aaggagtgtg agtaagctag ttttataact tgtatgtatc catatccaca ggcacattca
     3961 aagtgattgg atagtcaggt atgaaattgt agtaggtacc atctattaat gtttcttctc
     4021 acccagctct gatctcctgt gcctgtctct ccaggacatt aatggcggac ctggtttctt
     4081 gtttttcccc caaacatgtc tggtccagca ctggacagtg tgcagcccac aggcacagct
     4141 ctcatttttt ttacctgtca ccttgtcttt tccctgcagt ggcctcttga agtagtgaga
     4201 ctttaggggc ctgcggcgtt cagtgtctgc tctacgtgca catgcgtatt tctctgtctc
     4261 tcgtgtagct ggtataagtg ttggagcagt aaacagagca cattgtttgc ccttagtatg
     4321 gcagtgagca cgaggccagt gtccaaggag actgactgtc tcacactctg cgggcagcac
     4381 cagaggcacg gagcacggca cacggcgttt aggtggagcg ctcacgctgg gtttcttagt
     4441 attgttgagg atctaccatt ttaccacgcg tgctttgtct tacagggact gaatgagaat
     4501 ctgtaagtca gattctgcat ttcaaccaca aataacattt gttctaagag attcttgaag
     4561 tagtaaatat tgtaaaaatt taaaattctt tatttttcta gtaaaccttt tcgtacatta
     4621 atgtggctgc acattaattc tgaatttcag atgaaaagaa aataaagtgg acaatactta
     4681 accctcaagt atttccccgt gtgtctaagt cattgaccat agaaagctgg gtgcgctgac
     4741 taaagccgtg cgtttgggag gacgaaacaa gaggattgcc gagagttgaa gccccgagta
     4801 gcatcctgag gcacacaaac caaaagaaga aataaatact gataattagg atgtttctaa
     4861 tgtcacacgt tagtaaagca gggaccatgg aggggctcag cagctgagtt cctgggaccc
     4921 gaaggtctga ggagagacct gaccggagat ttgtcttccc cacaagtaaa tatgcaaatg
     4981 atcttcacaa ggtagaattc gccatagtta aaaacacgtg agttctgttg tttgcattga
     5041 actgttttct tgatgcatgg ttgactgaat atcaaagtgg gcaaatgtac gtgaagctga
     5101 ggccatggta tatccggtca cagctttaat ttttttatag tttttgtaac acccttgtat
     5161 aaagcctaaa ggtaaaccaa attttggcct atgtgggttt ctaatacaaa gtctgacatg
     5221 ttggtgtgtc taacaaggcc tcaggttaca gagatacata aacaaatgta gtttatttat
     5281 aaagaaagat tcaaaccata tattatttgg acgtcttttt ttttaaaaag cagagtggca
     5341 ctttgaggtt ttaatttaag atatttttct attctatttc ataaaaggtt taaaattttg
     5401 tgtataaata ttttttttaa ttgttcaaga atcttatgac ctggtgtagg gcagttttgc
     5461 aattttaaca ctatagcttt aatataaata acatttgtag aggttttctt tgaaataaag
     5521 gtgagactat tttgtcattt ttattatttc ctttagagcc tgaatagcct taaaataata
     5581 ggcataaaat gttgtgttct gatttttata ttgttaaaat ttagaaataa cgtacttacc
     5641 ttgatttctt tcccaagtta agtttgaaca gtgtcacata taactctctc tctgcaaaaa
     5701 gggtggaagc aggttagagc aggttttgtg taggtctatt atgtcaacta taccaaattg
     5761 cctctcagca tgagcaagat ggtgatagat gtgtttaacc tcactatctg ttctcactgt
     5821 ctcacagtct gccaggatca cactccacac agaataatgg atggatgaag tgtttgcaat
     5881 gagtgcttgt tcaccaggtg ctgtggggaa actgcagggc agaggaggac actgtagggt
     5941 tgagatacac aagcgacacc tgcccttcat acagacggag tgaagggacc tgtgcttgga
     6001 tggatatcta aacatcccca tgcacaggat tcaatattac gttcattcca taattcagtt
     6061 gcaatgtaat tattttgatt tatttaatct cattaaaaat aacttgcttt tggtagaacc
     6121 ctctaagaat agtaagacca ataaaattgc tgtgaatggc attttcagta atatgtcctg
     6181 aggacctgcc tggtctgtgg tttctccaga aggctgtagc cttgctgtcc tgttatgttc
     6241 ctcatggttt acattctttg gctgaagaaa acatgttttt aaattttatg attttataat
     6301 gatctctgtt tcttgtaaag aaaaatttca caaatttata ttctgatgcc tgtggttctt
     6361 gtgtgtgctt aagatgatta catttgggga gggtctcgag tcacggcttg ggatttgtat
     6421 agttagggga tatgaccatc gtagaaaacg taaaggctgg gcccttggtg ctgtgcactt
     6481 ggagaggaac ccaggatctt cagccatctt ccagtggcct tccccagccc tgagtcttct
     6541 cttggtttcc aggtccaata ctgccagttc agctgagaac accactggac gcgttcataa
     6601 atgtcctaag gtcctctgtt gggcttcatc agagagcctc attgatgacc actggtgcag
     6661 gcatgatgga cgtccacttg tgtgggcatg taagtctcag tgagtggttt gcatctcagc
     6721 ataccttctc catcttttca gtggtctgac ttctgaacaa gaggatatag ttgggacaca
     6781 taatggagaa gtgcactcgg tgtacaagtg actctgcact gagtgaggat ggacttgtat
     6841 cataagtcag aaaatgctgg aaacaaagca caggaagtcc taaggcgagc gggccgagtg
     6901 tactgctttt ggggacttca tttcccagtt cctagtatgg gctgcttaca accacctcta
     6961 acgccagctc acatgatttt gtacaaaccc tacataaaca taagttcagt gagaactaat
     7021 ctgtagccag tgtgctagct atagttagaa ctgggaggat gctatcagaa accttgtctt
     7081 aaaagggtca ctatacagag aaacaggtct cattgtgaca tgttccatat gtctccgttg
     7141 gtcccttcct ccccaacccc accttcatga tgggtctcgt ttccttgtca aatgtaattt
     7201 tagtcatcag ttcattaaaa acattataaa catcca
//
