LOCUS       NM_001127373            4263 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus ADNP homeobox 2 (Adnp2), mRNA.
ACCESSION   NM_001127373 XM_001057780 XM_225732
VERSION     NM_001127373.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4263)
  AUTHORS   Kushnir,M., Dresner,E., Mandel,S. and Gozes,I.
  TITLE     Silencing of the ADNP-family member, ADNP2, results in changes in
            cellular viability under oxidative stress
  JOURNAL   J Neurochem 105 (2), 537-545 (2008)
   PUBMED   18179478
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166606.1.
            
            On or before May 17, 2008 this sequence version replaced
            XM_225732.4, XM_001057780.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166606.1, DN936322.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..4263
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.3"
     gene            1..4263
                     /gene="Adnp2"
                     /gene_synonym="RGD1308279"
                     /note="ADNP homeobox 2"
                     /db_xref="GeneID:307236"
                     /db_xref="RGD:1308279"
     exon            1..262
                     /gene="Adnp2"
                     /gene_synonym="RGD1308279"
                     /inference="alignment:Splign:2.1.0"
     exon            263..383
                     /gene="Adnp2"
                     /gene_synonym="RGD1308279"
                     /inference="alignment:Splign:2.1.0"
     CDS             276..3686
                     /gene="Adnp2"
                     /gene_synonym="RGD1308279"
                     /note="ADNP homeobox protein 2"
                     /codon_start=1
                     /product="activity-dependent neuroprotector homeobox
                     protein 2"
                     /protein_id="NP_001120845.1"
                     /db_xref="GeneID:307236"
                     /db_xref="RGD:1308279"
                     /translation="MFQIPVQNLDNIRKVRKRVKGILVDIGLDSCKELLKDLKGFDPG
                     EKYFCNTSWGDVSLWEPSGKRAKYRTKPYCCSLCRYSTKVLTSLKNHLHRYHEEEADQ
                     ELMIPCPNCPFASQPKVVGKHFRMFHAPARKVQSYTVNILGEAKTSRSDVISFTCLKC
                     NFSNTLYYSMKKHVLVAHFNYLINSYFGLRTEETGEQPKASDPVSVDKALPFDKYYCK
                     KCSAIASSQDALMYHILTSDAHRDLENKLRSVISEHIKRTGFLKQMHIAPKPVTHIAL
                     PPNSSAPSIAAPPPCFQLALPQNSQSPGTVQSVTVAPGTSGSLTHSPPTTAQSHVALV
                     SSSLPVCQSSLTLQQSAPPPVFLSHSVPLSQPVSTSVLPLTQPLGPVNKSVGTSLLPV
                     NQAMCSVNQAVRPGVLPLPKPMGPINRPVGPGVLPVGPSVNSGVLQATSPGVISVGRA
                     VPSGVLPAGQVTPAGVIPGQTATSGVLPTGQVVQSSVLPVGQTAPSRVLPPGQTVPLR
                     VLPAGQVVPPGLLSPNQTVPSGVVPVNQGVNSGVLQLSQPVTPGVLPVGPPVRPGVLQ
                     LSPSVSTSILPVSQPVRAGTSQNTTFLTSGSILRQLIPTGKQVNGIPTYTLAPVSVTL
                     PVPSAGGLAAVGPPPQVPVQFLPSSSGTQMGSSLPSLPSPQVLVSPAPSVFVQATPPV
                     ADANQALRQAKQWKTCPVCNELFPANVYQVHMEVAHTQSEAKSSEKPEPERLAACAPF
                     LKWMREKTVRCLSCKCLVSQEELMHHLLMHGLGCLFCPCTFHDVRGLVEHSRTKHLGK
                     KRLSMDYSNRGFQLDLDANGNLLFPHLDFITILPREKLGEREVYLAILAGIHSKSLVP
                     VYVKVRPQPEVAPKIPNRQKLTCPFCFGTFMAADAYELHLKERHHVMPTVHTMLRSPA
                     FKCIHCCGVYTGNMTLGAIAVHLLRCRSAPKDSSSDLQAQPDFIESSELLMVNGEVIP
                     ESTFPLKRKLPEGHLGPEEQGDGDEPQLTVDTDASPGSEKGLSAVPLKRQKNESRTEG
                     SGASDDSLQVLALDPSKYGSRSYEEKKQFLRDYFHKRPYPSRKEVELLSSLLWVWKID
                     VASFFGKRRYICMKAIKSHKPSVLLGFDMSELKNVKHRLNFECESENL"
     exon            384..473
                     /gene="Adnp2"
                     /gene_synonym="RGD1308279"
                     /inference="alignment:Splign:2.1.0"
     exon            474..4252
                     /gene="Adnp2"
                     /gene_synonym="RGD1308279"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcgaggccc gcggggtcca ggggcctgga ggggcccgtg agatgagccc agggggtccc
       61 caggcacact ctacacccat tggctggcct cgtcggcatg caaataaggc aacgtcactt
      121 cctgaggcag ctgagcgcca tcttctcttt ctggcgcgcg ggaggaggga cgggcgcggg
      181 gcgggggtcc cgccgcgtag gcggaggacg cggcggtgtt gcgacggcgg cgggacgcgg
      241 cgctcctcgc gccccgtggt aggaaaatat caaaaatgtt tcaaattcct gtgcagaatc
      301 ttgacaacat cagaaaggtg cggaagaggg tgaaaggcat ccttgtggac attggacttg
      361 acagctgcaa ggagctgctg aaggatctta aaggctttga tccgggagag aagtactttt
      421 gtaatacatc gtggggagat gtttctcttt gggaaccttc tggaaagaga gcgaaataca
      481 gaacaaagcc ctactgctgt agtctctgca ggtactcaac gaaggtgctc acctccctca
      541 aaaatcacct gcaccgatac cacgaagagg aggctgacca ggagctcatg atcccctgcc
      601 ccaactgccc gtttgcctct cagcccaagg ttgtgggcaa gcacttcaga atgttccacg
      661 cgcctgcgcg gaaagtccag agctacacag tgaacatcct gggtgaggcg aagacttcaa
      721 ggagtgatgt gataagcttc acatgtttaa aatgtaactt ttcaaacact ctgtactaca
      781 gcatgaagaa gcatgtgctg gtggcccatt ttaattactt aattaactcc tactttggat
      841 tgcgaactga ggaaacagga gaacaaccga aagcaagtga tccagtttct gtggataaag
      901 ccctgccatt tgacaagtac tactgtaaaa aatgcagcgc catcgccagt agtcaggatg
      961 ccctgatgta tcacattctg acatcagatg cacataggga cttggagaat aagctgaggt
     1021 ctgttatctc agagcacatc aagaggaccg ggtttctgaa gcaaatgcat attgctccaa
     1081 agccagtgac ccacatagct ttaccgccaa acagcagtgc tccgagcatt gcagcccctc
     1141 ctccttgctt ccagcttgct ttgccacaga acagtcaaag tcccggcact gtgcagtcag
     1201 tgactgtggc cccaggcact tctgggagcc ttacacactc accacctacc acggcccagt
     1261 ctcatgtagc tctggtctcc agctctttgc ctgtgtgcca gagtagcctc accctgcagc
     1321 agtccgctcc cccacctgtc tttctctctc acagtgtccc actgagtcag cccgtcagta
     1381 cttctgtgct gcctctcact cagccacttg ggcctgtgaa taagtctgtt ggaacaagcc
     1441 tcctccctgt gaaccaagcc atgtgctccg tgaaccaagc tgtccgccct ggagttttac
     1501 ccctccctaa gcccatgggg cccataaaca gacctgtggg ccctggtgtc ttgcctgtgg
     1561 gtccctctgt taactcaggg gttctccagg ctacatctcc tggggtgatt tctgtaggtc
     1621 gagcagttcc atcaggagtc cttcctgcag gtcaggtgac ccctgctggt gtgatccctg
     1681 ggcagacagc cacttccggg gtcttaccca ctggccaggt ggtccagtcg tcagttctcc
     1741 ctgttggcca gacagcgcca tctcgagttc tccctcctgg ccagacagtg cccttgaggg
     1801 ttctccctgc aggccaggtg gtaccgcctg ggctgctttc tccaaaccaa actgtcccct
     1861 cgggagttgt ccctgtgaat caaggtgtga actctggtgt tcttcagctc agtcagccag
     1921 taacaccagg agtccttcct gtgggcccac ccgtgaggcc tggtgttctg cagctcagtc
     1981 cgtctgtcag caccagcatc ctgcccgtga gccagccggt gagagctgga acgtcccaaa
     2041 acactacttt ccttacttca ggttctattc tcagacagct cattccaact gggaaacagg
     2101 tgaatggaat ccccacctat acgctggccc cagtgtccgt cactctgccg gtgccctccg
     2161 ctggaggcct tgcagctgtt ggaccgccac cccaggtgcc agtgcagttc ctgccctcaa
     2221 gctcgggcac acagatgggc agctccttgc ccagcctgcc ctcgccacag gtgctagtga
     2281 gccctgcccc tagcgtgttt gttcaggcta ccccgcctgt ggcagatgca aatcaggcac
     2341 tcagacaggc caagcagtgg aaaacatgcc cagtttgcaa cgagctcttc cctgccaacg
     2401 tctaccaggt ccacatggaa gtggctcaca cgcagagcga ggccaagtcc agtgagaagc
     2461 ctgagcccga aaggcttgct gcatgcgccc catttctgaa gtggatgaga gagaagacag
     2521 tgcgctgcct ctcttgtaag tgcctggtct cgcaggagga gctgatgcac catttgctca
     2581 tgcatggcct ggggtgcctg ttctgtccat gcacttttca tgatgtccgg ggccttgtgg
     2641 agcacagcag gactaagcac ctgggcaaga agagactgtc tatggattac agtaacagag
     2701 gtttccagct ggacttggat gctaatggga acctgctgtt ccctcatctc gatttcatca
     2761 ccatactgcc acgagagaaa cttggagagc gagaagtgta cctggctatc cttgctggaa
     2821 tacactccaa gtcgttggtc cctgtgtacg ttaaggtgag gcctcagcct gaggttgcac
     2881 caaagatacc taacagacag aagctgacct gcccgttctg ttttggcaca ttcatggctg
     2941 ctgatgccta cgagctgcat ctgaaggaga ggcaccatgt catgcccaca gtccatacaa
     3001 tgctccggtc tccggccttt aagtgcatcc actgttgtgg ggtctacact ggaaacatga
     3061 ccttaggagc catcgctgtc catttgctcc gttgtagaag tgctccaaag gacagcagct
     3121 cagacctgca agcccagcca gattttatcg agagcagtga actgctgatg gtcaatgggg
     3181 aagtgatccc cgagtccacc tttcctctga agagaaagct gccagaaggc catttagggc
     3241 cagaagagca gggggacggg gacgagcccc agctcacagt agacaccgat gcgagcccag
     3301 gttcagagaa agggctgagt gctgtgcctt tgaagagaca gaagaatgag agcaggacag
     3361 aggggtcagg ggccagtgat gactccctgc aggtgttggc gttagacccc agtaagtatg
     3421 gaagtcgttc ctatgaggaa aagaaacagt tcctcagaga ctattttcac aagagaccat
     3481 atcctagtcg aaaagaagtg gaactactgt cctcgctctt gtgggtgtgg aaaatcgacg
     3541 tggcctcgtt ctttgggaaa aggaggtata tctgcatgaa agcaataaaa tcccacaagc
     3601 cctctgtact tctgggtttt gatatgtctg agcttaagaa tgtcaaacac aggctgaact
     3661 ttgagtgtga gtcagaaaac ctgtaggaga gtaagtctga agtctcctga cttccagccc
     3721 ttcccacctc tcgctctgtt gtaagtgtcc gaggcccttc aaggtgtccc aggtgctcag
     3781 aaagcctgaa aaggaagcac acactgccac agaggagctg ttctccgcag tttgcgttgc
     3841 ggctgtctgt tttccttctg tcatgtaaat taaatctttg gtattccatg cacgccttgt
     3901 ttccccacga gtgtcagtgt caatagcaac aacctggagt ctgcagatac ttggtttttc
     3961 attttagaga atttctgctt gtttgagaaa cttgattaat agaaaattga agcgttgctc
     4021 cctcttagtt cctagctgca gctagtgaca gtgtgtgttt agagaagcaa gcactctgat
     4081 gtgtatgact ccctaaggac atacttttaa gcattaactt ctgctgattc tgtgaccgac
     4141 gtttgcttaa ggctacaaat ttgatttaca ccttttcaag tgtcccctga cagctatttt
     4201 tttaatatca ttattcatta aaaaaatccc agatgttttc catttattaa aaaaaaaaaa
     4261 aaa
//
