LOCUS       NM_134408               5843 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Rattus norvegicus adhesion G protein-coupled receptor L2 (Adgrl2),
            transcript variant 1, mRNA.
ACCESSION   NM_134408
VERSION     NM_134408.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5843)
  AUTHORS   Vezain,M., Lecuyer,M., Rubio,M., Dupe,V., Ratie,L., David,V.,
            Pasquier,L., Odent,S., Coutant,S., Tournier,I., Trestard,L.,
            Adle-Biassette,H., Vivien,D., Frebourg,T., Gonzalez,B.J.,
            Laquerriere,A. and Saugier-Veber,P.
  TITLE     A de novo variant in ADGRL2 suggests a novel mechanism underlying
            the previously undescribed association of extreme microcephaly with
            severely reduced sulcation and rhombencephalosynapsis
  JOURNAL   Acta Neuropathol Commun 6 (1), 109 (2018)
   PUBMED   30340542
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5843)
  AUTHORS   Anderson,G.R., Maxeiner,S., Sando,R., Tsetsenis,T., Malenka,R.C.
            and Sudhof,T.C.
  TITLE     Postsynaptic adhesion GPCR latrophilin-2 mediates target
            recognition in entorhinal-hippocampal synapse assembly
  JOURNAL   J Cell Biol 216 (11), 3831-3846 (2017)
   PUBMED   28972101
REFERENCE   3  (bases 1 to 5843)
  AUTHORS   Um,J.W., Pramanik,G., Ko,J.S., Song,M.Y., Lee,D., Kim,H.,
            Park,K.S., Sudhof,T.C., Tabuchi,K. and Ko,J.
  TITLE     Calsyntenins function as synaptogenic adhesion molecules in concert
            with neurexins
  JOURNAL   Cell Rep 6 (6), 1096-1109 (2014)
   PUBMED   24613359
  REMARK    Erratum:[Cell Rep. 2024 Aug 27;43(8):114646. doi:
            10.1016/j.celrep.2024.114646.. PMID: 39110596]
REFERENCE   4  (bases 1 to 5843)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   5  (bases 1 to 5843)
  AUTHORS   Hoffert,J.D., Pisitkun,T., Wang,G., Shen,R.F. and Knepper,M.A.
  TITLE     Quantitative phosphoproteomics of vasopressin-sensitive renal
            cells: regulation of aquaporin-2 phosphorylation at two sites
  JOURNAL   Proc Natl Acad Sci U S A 103 (18), 7159-7164 (2006)
   PUBMED   16641100
REFERENCE   6  (bases 1 to 5843)
  AUTHORS   Tobaben,S., Sudhof,T.C. and Stahl,B.
  TITLE     The G protein-coupled receptor CL1 interacts directly with proteins
            of the Shank family
  JOURNAL   J Biol Chem 275 (46), 36204-36210 (2000)
   PUBMED   10958799
REFERENCE   7  (bases 1 to 5843)
  AUTHORS   Kreienkamp,H.J., Zitzer,H., Gundelfinger,E.D., Richter,D. and
            Bockers,T.M.
  TITLE     The calcium-independent receptor for alpha-latrotoxin from human
            and rodent brains interacts with members of the ProSAP/SSTRIP/Shank
            family of multidomain proteins
  JOURNAL   J Biol Chem 275 (42), 32387-32390 (2000)
   PUBMED   10964907
REFERENCE   8  (bases 1 to 5843)
  AUTHORS   Ichtchenko,K., Bittner,M.A., Krasnoperov,V., Little,A.R.,
            Chepurny,O., Holz,R.W. and Petrenko,A.G.
  TITLE     A novel ubiquitously expressed alpha-latrotoxin receptor is a
            member of the CIRL family of G-protein-coupled receptors
  JOURNAL   J Biol Chem 274 (9), 5491-5498 (1999)
   PUBMED   10026162
REFERENCE   9  (bases 1 to 5843)
  AUTHORS   Sugita,S., Ichtchenko,K., Khvotchev,M. and Sudhof,T.C.
  TITLE     alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an
            unusual family of ubiquitous G-protein-linked receptors. G-protein
            coupling not required for triggering exocytosis
  JOURNAL   J Biol Chem 273 (49), 32715-32724 (1998)
   PUBMED   9830014
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF063102.1, FM039554.1, AF081148.1, CB579130.1, AF081151.1,
            CO556290.1, FM099106.1, FM068641.1 and AA899882.1.
            
            On Oct 7, 2014 this sequence version replaced NM_134408.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF063102.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-373               AF063102.1         1-373
            374-420             FM039554.1         329-375
            421-793             AF081148.1         867-1239
            794-841             CB579130.1         525-572
            842-2952            AF063102.1         842-2952
            2953-3181           AF081151.1         3399-3627
            3182-3424           AF063102.1         3182-3424
            3425-3487           AF081151.1         3844-3906
            3488-3964           AF063102.1         3488-3964
            3965-4473           CO556290.1         68-576
            4474-5091           FM099106.1         82-699
            5092-5726           FM068641.1         5-639
            5727-5843           AA899882.1         1-117               c
FEATURES             Location/Qualifiers
     source          1..5843
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q45"
     gene            1..5843
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /note="adhesion G protein-coupled receptor L2"
                     /db_xref="GeneID:171447"
                     /db_xref="RGD:620835"
     exon            1..96
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..4487
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; latrophilin-2; calcium-independent
                     alpha-latrotoxin receptor 2; calcium-independent
                     alpha-latrotoxin receptor homolog 2"
                     /codon_start=1
                     /product="adhesion G protein-coupled receptor L2 isoform 1
                     precursor"
                     /protein_id="NP_599235.3"
                     /db_xref="GeneID:171447"
                     /db_xref="RGD:620835"
                     /translation="MVSSGCRMRSLWFIMIISFSPNTEGFSRAALPFGLVRRELSCEG
                     YSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQ
                     CVVVTGSDVFPDPCPGTYKYLEVQYECVPYMEQKVFVCPGTLKAIVDSPSIYEAEQKA
                     GAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVV
                     YDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENG
                     LWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQD
                     NESEAGKNVIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRY
                     SLEFGPPDPAQVPTTAVTITSSAELFKTTVSTTSSTSQRGPVSSTVAGPQEGSRGTKP
                     PPAVSTTKIPPVTNIFPLPERFCEALEMKGIKWPQTQRGMMVERPCPKGTRGTASYLC
                     MASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGTVFAGDVSSS
                     VRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAE
                     TLDCWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTDNIVLEVAVLSTE
                     GQVQDFTFHLGFKGAFSSIQLSANTVKQNSRNGLAKVVFIIYRSLGPFLSTENATVKL
                     GADLLGRNSTIAVNSHVLSVSINKESSRVYLTDPVLFSMPHIDSDNYFNANCSFWNYS
                     ERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIVYKDGVHKLLLTVITW
                     VGIVVSLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTQYTIAC
                     PVFAGLLHFFFLAAFSWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVS
                     AAIDYKSYGTLEACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPD
                     SSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVNE
                     ETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYAKCFRHWYCCGGLPTESPHSSVK
                     ASTSRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNP
                     LLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNNTRDTSAMDTLPLNGNFNNSY
                     SLRKADYHDGVQVVDCGLSLNDTAFEKMIISELVHNNLRGSNKTHNLELKLPVKPVIG
                     GSSSEDDAIVADASSLMHGDNPGLEFRHKELEAPLIPQRTHSLLYQPQKKVKPEATDS
                     YVSQLTAEADEHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSPSRRSENEDIYYK
                     SMPNLGAGRQLQMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL"
     exon            97..310
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            311..420
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            421..432
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            433..1233
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1234..1527
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1528..1631
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1632..1817
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1818..1856
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1857..2040
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..2166
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2167..2372
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2373..2546
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2547..2756
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2757..2977
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            2978..3044
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            3045..3136
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            3137..3181
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            3182..3208
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            3209..3377
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            3378..3506
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            3507..3603
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            3604..3732
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
     exon            3733..5827
                     /gene="Adgrl2"
                     /gene_synonym="Cirl-2; Cirl2; Cl2ac; Lphn2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaaatattt aaagggatca ataatggtgt cttctggttg cagaatgcga agtctctggt
       61 ttatcatgat aatcagtttc tcaccgaata ccgaaggttt cagcagagca gccttgccat
      121 tcgggttagt tagacgagag ctgtcctgtg aaggttattc tatagacctg cgatgtccgg
      181 gcagtgacgt catcatgatc gagagcgcaa actacggtcg gacggacgac aagatctgcg
      241 acgcagaccc ctttcagatg gagaacacag actgctacct ccctgatgcc ttcaaaatca
      301 tgactcaaag gtgcaacaac cgaacacagt gtgtagtagt taccgggtca gatgtatttc
      361 ctgatccatg tcctggaact tacaaatacc ttgaagttca atatgaatgt gtcccttaca
      421 tggagcaaaa agtttttgtg tgtcctggaa ccttgaaagc aattgtggac tctccaagta
      481 tctatgaagc tgagcaaaag gcaggtgctt ggtgcaagga cccccttcag gctgcagata
      541 aaatttattt tatgccctgg actccctacc gcaccgatac cttaatagaa tatgcttctt
      601 tagaagattt tcaaaacagc cgccagacaa caacatacaa acttccaaac cgagtggacg
      661 gtactggatt tgtggtgtat gacggggcag tcttcttcaa caaagaaaga acgagaaaca
      721 ttgttaaatt tgacttgagg actagaatca agagtgggga ggccataatc aactacgcca
      781 actaccatga cacttcaccc tacagatggg gggggaagac tgacattgac ctggcagtgg
      841 atgaaaatgg cttgtgggtc atctacgcca ccgagcagaa caacggaatg atcgtgatta
      901 gccagctcaa tccgtacact ctccgattcg aagcaacctg ggagacgacg tatgacaagc
      961 gtgcggcgtc caatgctttc atgatatgcg gggtcctcta cgtggtcagg tcagtgtacc
     1021 aagacaatga aagcgaagct ggcaagaacg tcatcgacta catttacaac acaaggttga
     1081 gccggggaga gcacgtggac gttcccttcc ccaaccagta ccagtacatc gctgcagtgg
     1141 attacaaccc aagagacaac caactctacg tatggaacaa taactttatc ttacggtatt
     1201 ctctggagtt tggtccaccc gaccctgccc aagtgcctac cacagctgtg acaataactt
     1261 cttcagctga gctgttcaaa accacagtgt caaccacaag cagtacttca cagagaggcc
     1321 ccgtgagcag cacagtcgct ggtcctcagg aaggaagccg agggacaaag ccacctccag
     1381 cagtctctac aaccaaaatt cctcctgtaa caaatatttt tcccctgcca gagagattct
     1441 gcgaagcgtt agaaatgaag gggataaagt ggcctcagac acaaaggggg atgatggttg
     1501 agcgaccgtg tcccaaggga acaagaggaa cggcctcgta tctctgcatg gcttccacag
     1561 gaacctggaa cccgaagggc ccggatctta gcaactgcac ctctcactgg gtgaatcagc
     1621 tggcccagaa gatcagaagt ggagagaatg ctgcaagtct ggccaacgaa ctggctaagc
     1681 acaccaaggg gacggtgttc gctggggatg tgagctcctc tgtgaggctg atggaacagt
     1741 tggtggacat cctggatgcc cagctgcagg agctgaaacc gagcgagaag gactcggccg
     1801 ggaggagtta taacaagctc caaaaacgag agaagacatg cagggcttac cttaaggcca
     1861 ttgtggacac agtagataac cttctgagag ccgagacttt ggactgctgg aaacacatga
     1921 attcctcaga gcaggcgcac acagccacca tgctgttgga caccttggaa gaaggagcat
     1981 ttgtcctggc agacaacctt ttggaaccaa cccgggtctc aatgccaacg gataatattg
     2041 ttctagaagt cgctgtcctc agcacggaag gacaggtcca agacttcacc ttccatctcg
     2101 gcttcaaggg ggccttcagc tccatccagc tctcagccaa caccgtcaag caaaacagca
     2161 gaaacgggct ggcaaaggtg gtattcatca tttaccggag tctgggacca ttcctgagca
     2221 ccgaaaatgc gaccgtcaaa ctgggcgcag acctcctggg tcggaacagc accatcgcag
     2281 tgaactcgca cgtcctttca gtctccatca ataaggagtc cagccgtgtg tacttgacag
     2341 acccggtgct tttttcaatg ccacacattg attctgacaa ttatttcaac gcaaactgct
     2401 ccttctggaa ctactcagag agaaccatga tgggatattg gtctacccag ggctgcaagc
     2461 tggttgacac taataaaact cgcacgacgt gtgcatgcag ccacctaacc aattttgcta
     2521 ttctcatggc ccacagggaa attgtgtaca aagatggcgt ccacaaattg ctgctgacag
     2581 tcatcacctg ggtgggcatc gttgtctccc tcgtctgcct ggctatctgc atcttcacct
     2641 tctgcttctt ccgaggcctg caaagcgacc gcaacacgat ccacaagaac ctgtgtatca
     2701 acctcttcat cgctgagttt attttcctaa taggcattga taaaacacag tacacgattg
     2761 cgtgccccgt gtttgcagga ctcctgcact ttttcttcct ggctgctttt tcctggatgt
     2821 gcctagaagg tgtgcagctc tacctcatgt tggttgaagt tttcgagagt gaatactcaa
     2881 ggaagaagta ttactatgtc gccgggtacc tcttccctgc cacagtggtc ggtgtttcag
     2941 ctgctatcga ctacaagagt tacgggacac tagaggcttg ctggcttcac gttgataact
     3001 atttcatatg gagtttcatt gggcctgtta ctttcatcat tctgctaaat attattttcc
     3061 tggtgatcac gctgtgcaaa atggtgaaac attcaaacac tttgaaacca gattctagca
     3121 ggttggaaaa cattaataat taccgtgttt gtgatggata ctataatacg gacttacctg
     3181 gctatgaaga taataagcca tttatcaagt cttgggtgct cggtgcgttc gccctgctgt
     3241 gtctcctggg cctaacctgg tcctttgggt tgctttttgt taacgaggag accgttgtca
     3301 tggcttatct cttcaccgcc tttaatgctt tccagggact gtttattttc atcttccact
     3361 gtgctcttca aaagaaagta cggaaagagt atgccaagtg cttcagacac tggtactgct
     3421 gtggtggcct cccgaccgag agcccgcaca gctctgtaaa ggcgtccacc tcccgcacca
     3481 gtgctcgcta ctcctctggt acacagagcc gtataagaag gatgtggaat gacaccgtga
     3541 ggaagcagtc tgaatcgtct tttatctcag gtgacatcaa tagcacttct acccttaatc
     3601 aaggaatgac tggcaattac ctactaacaa accctcttct tcgaccccac ggcactaaca
     3661 acccctataa cacattgctc gctgaaacag ttgtatgtaa tgccccttca gcgcccgtgt
     3721 ttaactcacc aggacattca ctgaacaata cccgggacac cagcgccatg gatactctac
     3781 cgctaaatgg taacttcaac aacagctact ccctgcgcaa ggccgactac cacgacggcg
     3841 tgcaggttgt ggactgtgga ctaagtctga acgacaccgc gtttgagaaa atgatcattt
     3901 cagagttagt gcacaacaac ctccggggta gcaacaaaac ccacaacttg gagctcaagc
     3961 tcccggttaa acccgtgatt ggcggcagca gcagcgaaga tgacgcgatc gtggccgacg
     4021 cctcatcttt gatgcacggt gataacccag ggctggaatt ccgccacaaa gagctggagg
     4081 caccgctcat ccctcagcgg actcactcgc ttctgtacca accccagaaa aaagtgaaac
     4141 ccgaggcaac cgacagctac gtctcccagc tgacggccga ggccgacgag cacctccagt
     4201 cccccaacag agactctctg tacacgagca tgcccaacct aagagactct ccctacccgg
     4261 agagcagccc ggacatggca gaggacctgt ctccctccag gaggagcgag aacgaggaca
     4321 tttactacaa aagtatgccc aatcttgggg ctggccgcca gctccagatg tgctaccaga
     4381 tcagcagagg caatagcgat ggctacatca tccccattaa caaagaaggg tgcatcccag
     4441 agggggacgt cagggaagga cagatgcagc tggtaacaag tctttaatag tacagctaag
     4501 gaattcctag ggccacatgc aagtattaac tgctaaagac tgtgccagcc ggccctgcag
     4561 ctctccccaa ctcggccagt agaaccggct ctgctggccg gcggttctcc actgtaggaa
     4621 aaaaaaatgg actgaacctc acggttctgt gaatttttat aaaacatgca aaaactttgt
     4681 atatacacag agtatactaa attgaattat ttgttacaaa gaaaaaagaa atgccaacca
     4741 ggtattttac gtttctgctg ctgtgtagag agattgtaaa acaaacagga gaccctccca
     4801 gccatgatcc cgcggcagtt ggtgaactga gtctgtaaat agaaccctac cgttttgggt
     4861 tttttttgtt tgtttgtttg tttttgtttt tgttttgtag gcctgcattg tattatatac
     4921 aagacgtagg ctttaagatc ctgtgggaca aattgactgt atcttacttt tcctgacaag
     4981 acttggaaaa gcaggagaga gattctgcac ccgtttgcac ttccctgcaa accttttaca
     5041 ttaaggcagc caccgaaacc atgtttaacc agtagcaatc aagccacagg ccttatctca
     5101 tgtttcctca actgtacaat gaactgttct catgaagaaa aaaaaagtta atggctaaag
     5161 aaaattatat tttgttctat tgctagggta aaaataaata catttgtgtc caactgagat
     5221 atcattaaaa taattttaaa aagagtttgg agaaaatatc gtgtcaagct cttggttgca
     5281 caaaataggc gatgtctctt ctcccaccca ccatggtgag tttctgcccc tctttgttgg
     5341 ttcccactgt agacggtgtc tgctctgacc gcttagcccc ctttcttaca cttaaatttc
     5401 ttattgccaa aagagtgtgt tttatgggga gaaaactctt tgaagtcctg ccatgccttg
     5461 cacaaatgtg gggaaatctg gaggtcttga gtcaaccctc tgtttattct ggaacagagg
     5521 gcgaaggggt cactgggcac ttctcacaaa ctttctagtg aacaaaaggt gcctattctt
     5581 ttataaaaaa ataaaataaa ataaaacaaa ataaaacaga aatattactc ttccatattc
     5641 cttctgccta tatttagtaa ttaatttatt ttatggtaaa gttctaatga cgtgtaaatt
     5701 gtttccgcaa agctctgctc ctctttcaag ccctttgtgt aaagctgtta ataacaagcc
     5761 tatcactaat atccagtgta aagtttaaca cggtttgaca gtaaataaat gtgaattttt
     5821 tcaagtaaaa aaaaaaaaaa aaa
//
