LOCUS       NM_022962               5579 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus adhesion G protein-coupled receptor L1 (Adgrl1),
            mRNA.
ACCESSION   NM_022962
VERSION     NM_022962.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5579)
  AUTHORS   Dannhauser,S., Lux,T.J., Hu,C., Selcho,M., Chen,J.T., Ehmann,N.,
            Sachidanandan,D., Stopp,S., Pauls,D., Pawlak,M., Langenhan,T.,
            Soba,P., Rittner,H.L. and Kittel,R.J.
  TITLE     Antinociceptive modulation by the adhesion GPCR CIRL promotes
            mechanosensory signal discrimination
  JOURNAL   Elife 9, e56738 (2020)
   PUBMED   32996461
  REMARK    GeneRIF: Antinociceptive modulation by the adhesion GPCR CIRL
            promotes mechanosensory signal discrimination.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5579)
  AUTHORS   Um,J.W., Pramanik,G., Ko,J.S., Song,M.Y., Lee,D., Kim,H.,
            Park,K.S., Sudhof,T.C., Tabuchi,K. and Ko,J.
  TITLE     Calsyntenins function as synaptogenic adhesion molecules in concert
            with neurexins
  JOURNAL   Cell Rep 6 (6), 1096-1109 (2014)
   PUBMED   24613359
REFERENCE   3  (bases 1 to 5579)
  AUTHORS   Boucard,A.A., Ko,J. and Sudhof,T.C.
  TITLE     High affinity neurexin binding to cell adhesion G-protein-coupled
            receptor CIRL1/latrophilin-1 produces an intercellular adhesion
            complex
  JOURNAL   J Biol Chem 287 (12), 9399-9413 (2012)
   PUBMED   22262843
  REMARK    GeneRIF: Neurexin 1 binding to latrophilin-1 produces a stable
            intercellular adhesion complex.
REFERENCE   4  (bases 1 to 5579)
  AUTHORS   Silva,J.P., Lelianova,V.G., Ermolyuk,Y.S., Vysokov,N.,
            Hitchen,P.G., Berninghausen,O., Rahman,M.A., Zangrandi,A.,
            Fidalgo,S., Tonevitsky,A.G., Dell,A., Volynski,K.E. and
            Ushkaryov,Y.A.
  TITLE     Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a
            high-affinity transsynaptic receptor pair with signaling
            capabilities
  JOURNAL   Proc Natl Acad Sci U S A 108 (29), 12113-12118 (2011)
   PUBMED   21724987
  REMARK    GeneRIF: Latrophilin 1 and its endogenous ligand Lasso/teneurin-2
            form a high-affinity transsynaptic receptor pair with signaling
            capabilities.
REFERENCE   5  (bases 1 to 5579)
  AUTHORS   Krasnoperov,V., Deyev,I.E., Serova,O.V., Xu,C., Lu,Y.,
            Buryanovsky,L., Gabibov,A.G., Neubert,T.A. and Petrenko,A.G.
  TITLE     Dissociation of the subunits of the calcium-independent receptor of
            alpha-latrotoxin as a result of two-step proteolysis
  JOURNAL   Biochemistry 48 (14), 3230-3238 (2009)
   PUBMED   19161337
  REMARK    GeneRIF: further cleavage of CIRL by a second protease results in a
            soluble form of CIRL
REFERENCE   6  (bases 1 to 5579)
  AUTHORS   Krasnoperov,V., Bittner,M.A., Holz,R.W., Chepurny,O. and
            Petrenko,A.G.
  TITLE     Structural requirements for alpha-latrotoxin binding and
            alpha-latrotoxin-stimulated secretion. A study with
            calcium-independent receptor of alpha-latrotoxin (CIRL) deletion
            mutants
  JOURNAL   J Biol Chem 274 (6), 3590-3596 (1999)
   PUBMED   9920906
REFERENCE   7  (bases 1 to 5579)
  AUTHORS   Sugita,S., Ichtchenko,K., Khvotchev,M. and Sudhof,T.C.
  TITLE     alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an
            unusual family of ubiquitous G-protein-linked receptors. G-protein
            coupling not required for triggering exocytosis
  JOURNAL   J Biol Chem 273 (49), 32715-32724 (1998)
   PUBMED   9830014
REFERENCE   8  (bases 1 to 5579)
  AUTHORS   Lelianova,V.G., Davletov,B.A., Sterling,A., Rahman,M.A.,
            Grishin,E.V., Totty,N.F. and Ushkaryov,Y.A.
  TITLE     Alpha-latrotoxin receptor, latrophilin, is a novel member of the
            secretin family of G protein-coupled receptors
  JOURNAL   J Biol Chem 272 (34), 21504-21508 (1997)
   PUBMED   9261169
REFERENCE   9  (bases 1 to 5579)
  AUTHORS   Krasnoperov,V.G., Bittner,M.A., Beavis,R., Kuang,Y., Salnikow,K.V.,
            Chepurny,O.G., Little,A.R., Plotnikov,A.N., Wu,D., Holz,R.W. and
            Petrenko,A.G.
  TITLE     alpha-Latrotoxin stimulates exocytosis by the interaction with a
            neuronal G-protein-coupled receptor
  JOURNAL   Neuron 18 (6), 925-937 (1997)
   PUBMED   9208860
REFERENCE   10 (bases 1 to 5579)
  AUTHORS   Davletov,B.A., Shamotienko,O.G., Lelianova,V.G., Grishin,E.V. and
            Ushkaryov,Y.A.
  TITLE     Isolation and biochemical characterization of a Ca2+-independent
            alpha-latrotoxin-binding protein
  JOURNAL   J Biol Chem 271 (38), 23239-23245 (1996)
   PUBMED   8798521
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF081146.1.
            
            [WARNING] On Jul 15, 2024 this sequence was replaced by
            NM_022962.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF081146.1, U72487.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..5579
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q11"
     gene            1..5579
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /note="adhesion G protein-coupled receptor L1"
                     /db_xref="GeneID:65096"
                     /db_xref="RGD:620768"
     exon            1..190
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            191..352
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     CDS             283..4698
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /note="latrophilin-1; CIRL-1; calcium-independent
                     alpha-latrotoxin receptor 1"
                     /codon_start=1
                     /product="adhesion G protein-coupled receptor L1
                     precursor"
                     /protein_id="NP_075251.1"
                     /db_xref="GeneID:65096"
                     /db_xref="RGD:620768"
                     /translation="MARLAAALWSLCVTTVLVTSATQGLSRAGLPFGLMRRELACEGY
                     PIELRCPGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQC
                     VVVAGSDAFPDPCPGTYKYLEVQYDCVPYKVEQKVFVCPGTLQKVLEPTSTHESEHQS
                     GAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVV
                     YDGAVFYNKERTRNIVKYDLRTRIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENG
                     LWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVD
                     DDSEAAGNRVDYAFNTNANREEPVSLAFPNPYQFVSSVDYNPRDNQLYVWNNYFVVRY
                     SLEFGPPDPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQL
                     GPDLPPATAPAPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVERPCPKGTR
                     GIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGENAANIASELARHTRGSIY
                     AGDVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETV
                     DNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKQNVVLE
                     VTVLSTEGQVQELVFPQEYASESSIQLSANTIKQNSRNGVVKVVFILYNNLGLFLSTE
                     NATVKLAGEAGTGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEAKNHFN
                     ANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINE
                     LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGID
                     KTQYEVACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCF
                     PALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIR
                     SSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQ
                     GVFIFVFHCALQKKVHKEYSKCLRHSYCCIRSPPGGAHGSLKTSAMRSNTRYYTGTQS
                     RIRRMWNDTVRKQTESSFMAGDINSTPTLNRGTMGNHLLTNPVLQPRGGTSPYNTLIA
                     ESVGFNPSSPPVFNSPGSYREPKHPLGGREACGMDTLPLNGNFNNSYSLRSGDFPPGD
                     GGPEPPRGRNLADAAAFEKMIISELVHNNLRGASGGAKGPPPEPPVPPVPGVSEDEAG
                     GPGGADRAEIELLYKALEEPLLLPRAQSVLYQSDLDESESCTAEDGATSRPLSSPPGR
                     DSLYASGANLRDSPSYPDSSPEGPNEALPPPPPAPPGPPEIYYTSRPPALVARNPLQG
                     YYQVRRPSHEGYLAAPSLEGPGPDGDGQMQLVTSL"
     exon            353..566
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            567..676
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            677..691
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            692..1492
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1807
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1808..1911
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1912..2097
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..2136
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            2137..2320
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            2321..2443
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            2444..2658
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            2659..2829
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            2830..3039
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            3040..3260
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            3261..3327
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            3328..3419
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            3420..3588
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            3589..3717
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            3718..3814
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            3815..3943
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            3944..3961
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
     exon            3962..5569
                     /gene="Adgrl1"
                     /gene_synonym="CL1BA; Lphn1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttttaaattt tggttggtgg cggcagtgct gggccggagg aaagaaggga cacggagtcc
       61 tccctcgctc agccaccccc tccccgcttc cccctgggcc gggctccggg agatgtgccg
      121 ggcggggggc ccggcttcgc ggagccgcgg gaggagcgcg cacggccgac cccgaagcgc
      181 cgctggacag gctggtgggc caggccttgg taccctggtg atgcggggca aggccccccc
      241 cacagtccgc tgagatcacc gtgcccgccc ctggccttcg ccatggcccg cttggctgca
      301 gcactctgga gtctctgtgt gacgactgtc ctcgtcacct ctgctaccca aggcctgagc
      361 cgggctggac tcccatttgg attgatgcgc cgggagctag catgcgaagg ctaccccatt
      421 gagctgcggt gcccgggcag tgacgtcatc atggtggaga atgcaaacta tgggcgcaca
      481 gatgacaaga tctgcgatgc cgaccctttt cagatggaga acgtgcagtg ctacctgcct
      541 gacgccttca aaatcatgtc acagagatgt aataaccgaa cccagtgtgt ggtggtggcc
      601 ggctctgacg cctttcctga cccctgtcct ggaacctaca agtacctgga ggtgcagtac
      661 gactgtgtcc cttacaaagt ggagcagaaa gtcttcgtgt gcccagggac actgcagaag
      721 gtgctggagc ccacctccac acatgaatcg gagcaccagt ctggcgcatg gtgcaaggac
      781 ccactgcagg caggtgaccg tatctacgtt atgccctgga tcccctaccg cacggacaca
      841 ctgaccgagt atgcttcctg ggaggactat gtggctgcac gccacaccac cacgtacaga
      901 ctgcccaacc gtgtagatgg cactggcttt gtggtatatg atggtgccgt cttctataac
      961 aaggaacgta ctcgcaacat tgtcaaatat gacctgcgga cccgcatcaa gagcggagaa
     1021 acagtcataa acacagccaa ctaccacgac acctcacctt atcgctgggg aggcaaaacc
     1081 gacattgacc tggcagtgga tgagaacggg ctgtgggtca tctatgccac cgaggggaac
     1141 aacgggcgtc tggtggtgag ccagctcaac ccctacacac tgcgtttcga gggcacctgg
     1201 gaaacaggct atgacaagcg ctcagcctcc aatgccttca tggtgtgtgg tgtcctctat
     1261 gtgctgcgct ctgtttatgt ggatgacgac agtgaggcag caggcaaccg cgtggactat
     1321 gcctttaaca ccaatgcaaa ccgagaggag cccgtcagtc tcgccttccc caacccctac
     1381 cagtttgtat cttctgttga ctacaatccc cgggacaacc agctgtatgt gtggaacaac
     1441 tatttcgtgg tgcgctacag cctggagttt ggacccccag atcccagtgc tggcccagcc
     1501 acttccccac ctctcagtac caccaccaca gctcggccta cgcccctcac cagcacagcc
     1561 tcacctgcag ccaccactcc actccgccgg gcgcccctca ccacgcaccc agtaggtgcc
     1621 atcaaccagc tgggacctga cctgcctcca gccacagccc cagcacccag tacccggcgg
     1681 cctccagccc ccaatctgca tgtgtcccct gagctcttct gtgaaccccg agaggtccgg
     1741 cgggtccagt ggccagctac ccagcagggt atgctggtag agagaccttg ccccaaggga
     1801 actcgaggaa ttgcctcgtt ccagtgcctc ccagctctgg ggctctggaa tcctcggggc
     1861 cctgacctca gcaactgcac ttccccctgg gtcaaccaag tcgcccagaa gatcaagagt
     1921 ggagagaatg cagccaacat tgctagtgag ctggcccgcc acacgcgggg ctccatctat
     1981 gctggggacg tgtcctcatc ggtgaagctg atggagcaac tgctagatat cctggatgcc
     2041 cagctccagg ccctacggcc cattgaacga gagtcagctg gcaagaacta caataagatg
     2101 cacaagcgag agagaacctg caaggactat atcaaggctg tggtggagac agtggacaac
     2161 ctgcttcggc cagaggcact tgagtcatgg aaagacatga atgccaccga acaggtccat
     2221 acggccacca tgctcctaga tgtcttagag gagggtgcct tcctgctggc cgacaatgtc
     2281 agagaacctg ctcgcttctt ggctgccaag cagaatgtgg tcctggaggt cactgtcctg
     2341 agcacagagg gtcaagtgca ggagttggtg ttcccccagg agtatgccag tgagagctcc
     2401 attcagctgt ccgccaacac catcaagcag aacagccgca atggtgtggt gaaggttgtc
     2461 ttcattctct acaacaacct gggcctcttc ttgtccacgg agaatgccac agtgaagctg
     2521 gcaggtgagg cagggaccgg tggccctgga ggtgcctccc tggtggttaa ctcacaggtc
     2581 atcgcagcat ccatcaataa ggagtccagc cgtgtcttcc tcatggaccc tgtcatcttt
     2641 actgtggccc acttggaggc caagaaccac ttcaatgcaa actgctcctt ctggaactac
     2701 tcagagcgct ccatgctggg ctactggtca acccagggct gccgactggt ggagtccaat
     2761 aagacccata ccacatgtgc ctgcagccac ctcaccaact tcgcagtgct catggctcac
     2821 cgagagatct accaaggccg tattaatgag ctgttgctgt cagtcatcac ctgggttggc
     2881 attgtcatct ccctggtctg tctggctatc tgcatctcca ccttctgctt cctgcggggc
     2941 ctgcagaccg accgcaacac catccacaag aacctgtgca tcaacctctt ccttgcagag
     3001 ctgctcttcc tggttggaat agacaaaact cagtatgagg tcgcctgccc tatctttgcg
     3061 ggcctgctgc actacttctt cctggccgcc ttctcctggc tgtgcctaga gggcgtgcac
     3121 ctctacctcc tgctggtcga ggtgttcgag agcgaatatt cacgcaccaa gtactattac
     3181 ctgggcggct actgcttccc agccctggtg gtaggcatcg cagccgccat tgactaccga
     3241 agctacggca ctgagaaggc ctgctggctg agggtggata actatttcat ctggagcttc
     3301 attgggcccg tctcctttgt tattgtggtg aacctggtgt tcctcatggt gaccctgcac
     3361 aagatgatcc gaagctcatc cgtgctcaag cctgactcca gccgccttga caacatcaag
     3421 tcctgggcgc tgggtgccat tgcactgctc ttcctgctgg gcctcacctg ggctttcggc
     3481 ctcctcttca tcaacaagga gtcagtagta atggcttacc tcttcacaac cttcaacgcc
     3541 ttccaggggg tcttcatctt tgtctttcac tgcgccttac agaaaaaggt gcacaaggag
     3601 tacagcaagt gcctgcgtca ctcctactgc tgcattcgct ccccacctgg gggggctcac
     3661 ggctccctta agacctcagc catgcgaagt aacacccgct actacacagg gacccagagc
     3721 cgaatccgga ggatgtggaa tgacaccgtg aggaagcaga cagagtcgtc ctttatggca
     3781 ggggacatca acagcacccc caccctgaac cgaggtacca tggggaacca cctactgacc
     3841 aaccctgtgc tacagccccg tgggggcact agcccataca atacactcat tgcagagtct
     3901 gtgggcttca atccctcctc gcccccagtc ttcaactccc caggaagcta cagggaacct
     3961 aagcacccct tgggcggccg ggaagcctgt ggcatggaca cactgcccct taatggcaac
     4021 ttcaacaaca gctactcctt gcgaagtggt gatttccctc cgggggatgg gggtcctgag
     4081 ccaccccgag gccgaaacct agcggatgct gcggcctttg agaagatgat catctcagag
     4141 ctggtgcaca acaaccttcg gggggccagt gggggcgcca aaggtcctcc accagagcct
     4201 cctgtgccac ccgtgccagg agtcagtgag gacgaggctg gtgggcctgg gggtgctgac
     4261 cgggctgaga ttgaacttct ctacaaggcc ctggaggagc cactgctgct gccccgggcc
     4321 cagtcggtgc tgtaccagag tgatctggat gagtcggaga gctgtacggc agaggatggg
     4381 gccaccagcc ggcccctctc ctcccctccc ggccgggact ccctctatgc cagcggggcc
     4441 aacctgcggg actcgccctc ctacccggac agcagccccg aagggcctaa tgaggccctg
     4501 ccccctcccc cacctgctcc ccctgggccc ccagaaatct actacacctc tcgcccgccg
     4561 gccctggtgg ctcggaatcc cctacagggc tactaccagg tgcggcggcc cagccatgag
     4621 ggctacctgg cagcccccag ccttgagggg ccagggcccg atggggatgg gcaaatgcag
     4681 ttggtcacta gtctctgagg ggcctcatgg accagaggcc tggccaggga gggaatccag
     4741 gaggggctct ggtgggagca gagactgatg gaggcagtgg ctggtgggcc actctctcca
     4801 ggtgcccctc tgcctgtggg ccccacagtc cccttgggga ctatgacctg ggccccaggt
     4861 gccagggtta gtagacaggg tttccaccag ccacaagccc cagcctcttt aggggagtgc
     4921 attgaggaga agcccccagg gccctaggag tgagggagaa gctggtaggt gtgaccaacg
     4981 tccaaagctc cctccctttg gagggagaaa gcaagggata aggcttccct aggtgtacag
     5041 gggtggccac ttttgaggtg gccgaagcct tgcaggatac accctatctg ctgctcactc
     5101 ttcttcgtcc accagaaagg agcagtggga cagatggaca gggtccttcc atgctacagt
     5161 tccttgcttc ttggagactg ggccttacat cctgagagag cccaggccca ggggatggat
     5221 ggggttgtga gggctggtgg ttaatggtgg aactttctct gaagctcctt tctcccttgc
     5281 tattggtccc tatctcccga gcaagcctac cctaaacccc cagagtgcac ccaatgaccc
     5341 cctcccttgg ggtgactcct gatgaagcac aactccccgc agggccccaa cccactgcag
     5401 tggccatatt tgggcagttc ccagtcctgt gggctgggct atctggggag cagatgtggg
     5461 gtctggggct ccctgaggag tgggtcctgg gtttggatct ttccctaggg ggtcctctta
     5521 cccttctctt cctcccctat tgctgtaaat atttcaacaa aatggaaaaa aaaaaaaaa
//
