LOCUS       NM_001007557            3226 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus adhesion G protein-coupled receptor E1 (Adgre1),
            mRNA.
ACCESSION   NM_001007557 XM_236797
VERSION     NM_001007557.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3226)
  AUTHORS   Zubiria,M.G., Vidal-Bravo,J., Spinedi,E. and Giovambattista,A.
  TITLE     Relationship between impaired adipogenesis of retroperitoneal
            adipose tissue and hypertrophic obesity: role of endogenous
            glucocorticoid excess
  JOURNAL   J Cell Mol Med 18 (8), 1549-1561 (2014)
   PUBMED   24913911
REFERENCE   2  (bases 1 to 3226)
  AUTHORS   Yang,C.Y., Chen,J.B., Tsai,T.F., Tsai,Y.C., Tsai,C.Y., Liang,P.H.,
            Hsu,T.L., Wu,C.Y., Netea,M.G., Wong,C.H. and Hsieh,S.L.
  TITLE     CLEC4F is an inducible C-type lectin in F4/80-positive cells and is
            involved in alpha-galactosylceramide presentation in liver
  JOURNAL   PLoS One 8 (6), e65070 (2013)
   PUBMED   23762286
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3226)
  AUTHORS   Matsubara,R., Kukita,T., Ichigi,Y., Takigawa,I., Qu,P.F.,
            Funakubo,N., Miyamoto,H., Nonaka,K. and Kukita,A.
  TITLE     Characterization and identification of subpopulations of
            mononuclear preosteoclasts induced by TNF-alpha in combination with
            TGF-beta in rats
  JOURNAL   PLoS One 7 (10), e47930 (2012)
   PUBMED   23110133
REFERENCE   4  (bases 1 to 3226)
  AUTHORS   Osorio,K.M., Lilja,K.C. and Tumbar,T.
  TITLE     Runx1 modulates adult hair follicle stem cell emergence and
            maintenance from distinct embryonic skin compartments
  JOURNAL   J Cell Biol 193 (1), 235-250 (2011)
   PUBMED   21464233
REFERENCE   5  (bases 1 to 3226)
  AUTHORS   Hamann,J.
  TITLE     The EGF-TM7 family of the rat
  JOURNAL   Immunogenetics 56 (9), 679-681 (2004)
   PUBMED   15578266
REFERENCE   6  (bases 1 to 3226)
  AUTHORS   Brown,G.D., Taylor,P.R., Reid,D.M., Willment,J.A., Williams,D.L.,
            Martinez-Pomares,L., Wong,S.Y. and Gordon,S.
  TITLE     Dectin-1 is a major beta-glucan receptor on macrophages
  JOURNAL   J Exp Med 196 (3), 407-412 (2002)
   PUBMED   12163569
REFERENCE   7  (bases 1 to 3226)
  AUTHORS   Ioan-Facsinay,A., de Kimpe,S.J., Hellwig,S.M., van Lent,P.L.,
            Hofhuis,F.M., van Ojik,H.H., Sedlik,C., da Silveira,S.A.,
            Gerber,J., de Jong,Y.F., Roozendaal,R., Aarden,L.A., van den
            Berg,W.B., Saito,T., Mosser,D., Amigorena,S., Izui,S., van
            Ommen,G.J., van Vugt,M., van de Winkel,J.G. and Verbeek,J.S.
  TITLE     FcgammaRI (CD64) contributes substantially to severity of
            arthritis, hypersensitivity responses, and protection from
            bacterial infection
  JOURNAL   Immunity 16 (3), 391-402 (2002)
   PUBMED   11911824
REFERENCE   8  (bases 1 to 3226)
  AUTHORS   Barnes,N., Gavin,A.L., Tan,P.S., Mottram,P., Koentgen,F. and
            Hogarth,P.M.
  TITLE     FcgammaRI-deficient mice show multiple alterations to inflammatory
            and immune responses
  JOURNAL   Immunity 16 (3), 379-389 (2002)
   PUBMED   11911823
REFERENCE   9  (bases 1 to 3226)
  AUTHORS   Tamura,K., Sudo,T., Senftleben,U., Dadak,A.M., Johnson,R. and
            Karin,M.
  TITLE     Requirement for p38alpha in erythropoietin expression: a role for
            stress kinases in erythropoiesis
  JOURNAL   Cell 102 (2), 221-231 (2000)
   PUBMED   10943842
REFERENCE   10 (bases 1 to 3226)
  AUTHORS   McKnight,A.J., Macfarlane,A.J., Dri,P., Turley,L., Willis,A.C. and
            Gordon,S.
  TITLE     Molecular cloning of F4/80, a murine macrophage-restricted cell
            surface glycoprotein with homology to the G-protein-linked
            transmembrane 7 hormone receptor family
  JOURNAL   J Biol Chem 271 (1), 486-489 (1996)
   PUBMED   8550607
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001007557.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY686632.1, SRR26360186.1859910.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-51                JAXUCZ010000009.1  2329440-2329490
            52-114              JAXUCZ010000009.1  2341790-2341852
            115-261             JAXUCZ010000009.1  2379632-2379778
            262-417             JAXUCZ010000009.1  2380737-2380892
            418-537             JAXUCZ010000009.1  2380970-2381089
            538-684             JAXUCZ010000009.1  2390285-2390431
            685-834             JAXUCZ010000009.1  2391755-2391904
            835-975             JAXUCZ010000009.1  2409565-2409705
            976-1122            JAXUCZ010000009.1  2409790-2409936
            1123-1211           JAXUCZ010000009.1  2412614-2412702
            1212-1295           JAXUCZ010000009.1  2419044-2419127
            1296-1473           JAXUCZ010000009.1  2422256-2422433
            1474-1593           JAXUCZ010000009.1  2439035-2439154
            1594-1778           JAXUCZ010000009.1  2442152-2442336
            1779-1949           JAXUCZ010000009.1  2443263-2443433
            1950-2144           JAXUCZ010000009.1  2446079-2446273
            2145-2380           JAXUCZ010000009.1  2470318-2470553
            2381-2447           JAXUCZ010000009.1  2473994-2474060
            2448-2539           JAXUCZ010000009.1  2477927-2478018
            2540-2708           JAXUCZ010000009.1  2480536-2480704
            2709-2813           JAXUCZ010000009.1  2482631-2482735
            2814-3226           JAXUCZ010000009.1  2484547-2484959
FEATURES             Location/Qualifiers
     source          1..3226
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..3226
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /note="adhesion G protein-coupled receptor E1"
                     /db_xref="GeneID:316137"
                     /db_xref="RGD:1359214"
     exon            1..51
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..2819
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /note="EGF-like module-containing mucin-like hormone
                     receptor-like 1; EMR1 hormone receptor; cell surface
                     glycoprotein EMR1; EGF-like module receptor 1; EGF-like
                     module containing, mucin-like, hormone receptor-like
                     sequence 1; adhesion G protein-coupled receptor E2"
                     /codon_start=1
                     /product="adhesion G protein-coupled receptor E2
                     precursor"
                     /protein_id="NP_001007558.1"
                     /db_xref="GeneID:316137"
                     /db_xref="RGD:1359214"
                     /translation="MWGFWLLLFWGFSGTHRWGMTTLAILGQRLNGVNECQDTTTCPA
                     YATCTDTTESYYCTCKQGFLPSNGQTNFQGPGVECQDVNECLRSDSPCGSNSVCTNIP
                     GRARCSCLSGFSSSAGGSWILGSPGHFLCTDVDECLTIGICPKNSNCSNSVGSYSCTC
                     QSGFVSNGSTCEDEDECVTRNACPEHATCHNTLGSYYCTCNEGLEFSGGGPMFQGLEE
                     SCEDVDECSRNSTLCGPSFICINTLGSYSCSCPAGFSLSTFQIPGHPADGNCTDIDEC
                     DDICPSNSSCTNTLGSYFCTCHPGFASSNGQLNFTDQEVTCEDIDECTQDPFRCGRNS
                     SCTNVPGSYNCSCLPDFRMDPGGSQAHGNFTCKRIPFKCKEDLIPKSEQIEQCQAGQG
                     RNLDYTSFCTFVNATFTILDNTCENKSAPVSLQSAATSVSLMLEQASTWFEFSREETS
                     TLGTILLETVESTMLAALLTPSGNASQTIRTEYLEIESKVINEECNEENVSINLKARG
                     DKMDVGCFIIKESESTGTPGVAFVSFAHMDSVLDERFFEDGQASWKLRMNSHVVGGTV
                     TGERKEDFSKPIVYTLQHIQPKQKSERSICVSWNTDVEDGRWTPSGCETVEASETHTV
                     CSCNRMTNLAIIMASGELTMEFSLYIISYVGTVISLVCLALAIATFLLFRAVQNHNTY
                     LHLHLCVCLFLAKILFLTGIDKTDNQTACAIIAGFLHYLFLACFFWMLVEAVMLFLMV
                     RNLKVVNYFSSRNIKMLHLCAFGYGLPVVVVIISATVHPWGYGMHNRCWLNTETGFIW
                     SFLGPVCMIITINSALLAWTLWVLRQKLCSVNSEVSKLKDTRLLTFKAIAQIFILGCS
                     WVLGIFQIGPLASIMAYLFTTINSLQGAFIFLIHCLLNRQVRDEYRKLLTRKTDLSSH
                     SQTSGILLSSMPSTSKTG"
     exon            52..114
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            115..261
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            262..417
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            418..537
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            538..684
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            685..834
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            835..975
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1122
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1211
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1212..1295
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1473
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1474..1593
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1594..1778
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1779..1949
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1950..2144
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2145..2380
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2381..2447
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2448..2539
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2540..2708
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2709..2813
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2814..3226
                     /gene="Adgre1"
                     /gene_synonym="Emr1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgaatagttg ccacagtata atgtggggct tttggctgct cctcttctgg ggcttcagtg
       61 gaacgcacag atgggggatg accacacttg ccatcctggg acaaagactt aacggtgtga
      121 atgaatgtca agacactacc acttgtccag cttatgccac ctgcactgac accacggaga
      181 gttattactg tacctgtaaa caaggttttc tgcccagcaa tggacaaacc aactttcagg
      241 gcccaggagt ggaatgtcaa gatgttaatg aatgtcttag aagcgactcg ccttgtggtt
      301 ctaactcagt ctgcaccaat atcccaggac gagccaggtg cagttgtctt agtggcttct
      361 cttcttccgc tggtggaagt tggatcctgg gaagtccggg tcattttctc tgcacagatg
      421 ttgacgagtg tctgacaatt gggatctgcc ctaagaattc taactgctct aactctgtgg
      481 ggagctacag ctgcacctgc caatcaggct ttgtctcgaa tggctccact tgtgaagatg
      541 aagatgaatg tgtgactcgt aatgcttgcc cagagcatgc aacctgccac aacactcttg
      601 gaagctatta ttgtacatgc aacgaaggac ttgaatttag tggaggagga ccaatgttcc
      661 agggcctgga agaatcttgt gaagatgtgg atgagtgctc caggaattca acgctttgtg
      721 gtccctcctt catttgcatc aacacgctgg gatcctacag ctgttcttgc ccagctggat
      781 tctctttgtc aacttttcag atccctggtc atccagcaga tgggaattgt acagatatag
      841 atgagtgtga tgacatatgc ccttccaact catcatgtac caacaccctt gggagctact
      901 tctgcacttg ccaccctggc tttgcctcaa gcaatggaca gctgaatttc acagaccaag
      961 aagtgacatg tgaagatatt gatgagtgca ctcaagatcc atttcgatgt ggacgaaatt
     1021 cttcctgcac caatgtacca ggttcctaca actgcagctg tcttcccgac tttcgaatgg
     1081 atccaggagg ctcccaagca catggaaact tcacatgcaa aaggattccc ttcaagtgta
     1141 aggaagactt gatacccaaa agtgagcaga tagagcagtg ccaagcaggg caaggccgga
     1201 atcttgatta tacttccttc tgcacatttg tgaatgccac ctttaccatc ctggataaca
     1261 cctgtgaaaa caaaagtgct ccagtgtcct tacagagtgc agctacaagt gtctccctca
     1321 tgctggagca agcatcgacc tggtttgagt tcagcaggga agagacatct actctgggca
     1381 ctatcttgct ggagactgtg gaaagcacca tgttggctgc tcttctgaca ccctctggga
     1441 atgccagtca gaccattcgg acggagtact tggaaattga aagcaaagtc atcaatgaag
     1501 aatgcaatga ggagaatgtg tccattaact tgaaagccag aggggacaag atggatgttg
     1561 gctgtttcat aatcaaagaa tcagaatcta cagggacccc aggagtggct tttgtctcct
     1621 ttgcacacat ggactcagtt ttagatgagc gcttctttga agatggtcag gcctcctgga
     1681 aactgaggat gaattcccat gttgttggtg gcactgtaac cggggagagg aaggaggact
     1741 tctccaagcc tatcgtctat accctccagc acatccagcc aaagcagaag tctgagaggt
     1801 ctatatgtgt ctcctggaac accgatgtgg aggatgggag atggacaccc tcgggctgtg
     1861 agactgtaga agcatctgag acacacacag tctgcagctg taaccggatg acaaatttgg
     1921 ccatcatcat ggcttctggg gagcttacaa tggaattttc cttgtatatc atcagctatg
     1981 tgggtacagt catctctctg gtatgtctcg ccttggccat agccaccttc ctgttgtttc
     2041 gtgcagttca gaaccacaac acctacctgc acctgcacct ttgtgtgtgt ctcttcttgg
     2101 ccaagattct cttcctcacc ggtatagaca agactgacaa ccagacagct tgcgctatca
     2161 ttgcgggatt tctacactat cttttccttg cctgcttctt ctggatgctg gtggaggcag
     2221 tgatgctctt cctgatggtg agaaacctga aggtggtgaa ttatttcagc tctcgcaaca
     2281 tcaagatgct gcacctctgt gcctttggct atgggctccc agtcgtggtg gtcattatct
     2341 ctgctactgt acatccatgg ggctatggaa tgcataatcg ctgctggctg aatacggaga
     2401 caggattcat ttggagtttc ttggggccag tctgcatgat catcacgatc aactctgccc
     2461 tccttgcctg gacactgtgg gtgctgaggc agaagctctg cagtgtcaac tcagaagtct
     2521 ctaagctcaa ggatacgagg ttgctgacct tcaaggccat tgcccagatt ttcatcttgg
     2581 gttgctcctg ggtgctgggc attttccaga ttggtccctt ggcaagcata atggcatacc
     2641 tgttcaccac tatcaacagc cttcaggggg ccttcatctt cctcattcac tgtctgctca
     2701 accgccaggt acgagatgaa tataggaaac tcctcaccag gaagactgat cttagctccc
     2761 attcccagac ttctgggatt ttactgtcat ctatgccttc cacttctaag acgggttaac
     2821 atttttcttg cttttaaata tattatggag caacatttga ggattgtaag tgcttcaaga
     2881 ctacttcgaa tcattatata gcttatggaa atttaaggta tcgttagttg gcggcagctt
     2941 tatatttaac tcaaaacatg gataagtgga accaaactcc aagagcttca tgcaccaagg
     3001 agaaacataa gttacttact caaatgaact caaatgtctt ctgtgccttg caactatgaa
     3061 gctccacatg ttttgaaaag agcatatcca gtttcaatgc cacaagggat tagcattttt
     3121 gtgtcttcta tgtcctttct tgtggggttc cagaaattct catttaacac ctatcaagta
     3181 gtgagcacag aatagctctc aataaagtat ttgttgtctg tctgaa
//
