LOCUS       NM_001107914            5001 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus adhesion G protein-coupled receptor B2 (Adgrb2),
            mRNA.
ACCESSION   NM_001107914 XM_001062170 XM_001062231 XM_001062290 XM_232778
VERSION     NM_001107914.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5001)
  AUTHORS   Purcell,R.H., Toro,C., Gahl,W.A. and Hall,R.A.
  TITLE     A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2)
            increases receptor signaling activity
  JOURNAL   Hum Mutat 38 (12), 1751-1760 (2017)
   PUBMED   28891236
REFERENCE   2  (bases 1 to 5001)
  AUTHORS   Um,J.W., Pramanik,G., Ko,J.S., Song,M.Y., Lee,D., Kim,H.,
            Park,K.S., Sudhof,T.C., Tabuchi,K. and Ko,J.
  TITLE     Calsyntenins function as synaptogenic adhesion molecules in concert
            with neurexins
  JOURNAL   Cell Rep 6 (6), 1096-1109 (2014)
   PUBMED   24613359
REFERENCE   3  (bases 1 to 5001)
  AUTHORS   Kee,H.J., Koh,J.T., Kim,M.Y., Ahn,K.Y., Kim,J.K., Bae,C.S.,
            Park,S.S. and Kim,K.K.
  TITLE     Expression of brain-specific angiogenesis inhibitor 2 (BAI2) in
            normal and ischemic brain: involvement of BAI2 in the
            ischemia-induced brain angiogenesis
  JOURNAL   J Cereb Blood Flow Metab 22 (9), 1054-1067 (2002)
   PUBMED   12218411
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            [WARNING] On Mar 20, 2025 this sequence was replaced by
            NM_001107914.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001062290.1, XM_001062231.1, XM_232778.4, XM_001062170.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132287,
                              SAMD00132293 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..5001
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..5001
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /note="adhesion G protein-coupled receptor B2"
                     /db_xref="GeneID:313058"
                     /db_xref="RGD:1309431"
     exon            1..823
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..4698
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /note="brain-specific angiogenesis inhibitor 2"
                     /codon_start=1
                     /product="adhesion G protein-coupled receptor B2
                     precursor"
                     /protein_id="NP_001101384.1"
                     /db_xref="GeneID:313058"
                     /db_xref="RGD:1309431"
                     /translation="MTPACPLLLSVILSLRLATAFDPAPSACSALASGVLYGAFSLQD
                     LFPTIASGCSWTLENPDPTKYSLYLRFNRQEQVCTHFAPRLLPLDHYLVNFTCLRPGP
                     EEATARAESEVGRPEEEAEAEAAATGLELCGGSGPFTFLHFDKNFVQLCLSAEPSEAP
                     RLLAPAALAFRFVEVLLINNNNSSQFTCGVLCRWSEECGRAAGRACGFAQPGCSCPGE
                     AGASPATTTPPGPPAAHTLSNALVPGGPAPPAEADLHSGSSNDLFTTEMRYGEEPEEE
                     PKVKTQWPRSADEPGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTL
                     CSGPLRETRPCNNSATCPVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACE
                     GPELQTKLCSMAACPVEGQWLEWGPWGPCSSSCANGTQQRSRKCSVAGPAWATCAGAL
                     TDTRECSNFDCPATDGKWGPWNAWSLCSKTCDTGWQRRFRMCQASGTQGYPCEGTGEE
                     VKPCSEKRCPAFHEMCRDEYVMLMTWKRAAAGEIIYNKCPPNASGSASRRCLLSAQGV
                     AYWGLPSFARCISHEYRYLYLSLREHLAKGQRMLAGEGMSQVVRSLQELLARRTYYSG
                     DLLFSVDILRNVTDTFKRATYVPSADDVQRFFQVVSFMVDSENKDKWDDAQQVSPGSV
                     HLLRVVEDFIHLVGDALKAFQSSLIVTDNLVISIQREPISAVSSDITFPMRGRRGMKD
                     WVRHSEDRLFLPKEVLSLSSPGKPATPGAATAGSPGRGRGPGTVPPGPGPAHQRLLPA
                     DPEESSSYFVIGAVLYRTLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAEPLITVELS
                     YIINGTTDPHCASWDYSRADASLGDWNTESCQTLETQAAHTRCQCQHLSTFAVLAQPP
                     KDLTLELAGAPSVPLVIGCAVSCMALLTLLAIYAAFWRFIKSERSIILLNFCLSILAS
                     NILILVGQSRVLSKGVCTMTAAFLHFFFLSSFCWVLTEAWQSYLAVIGRMRTRLVRKR
                     FLCLGWGLPALVVAVSVGFTRTKGYGTSSYCWLSLEGGLLYAFVGPAAVIVLVNMLIG
                     IIVFNKLMARDGVSDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMAS
                     LWSSCVVLPLLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQD
                     VVKCQMGVCRTDESEDSPDSCKNGQLQILSDFEKDVDLACQTVLFKEVNTCNPSTITG
                     TLSRLSLDEDEEPKSCLVGPEGGLSFSPLPGNILVPMAASPGLGEPPPPQETNPVYMC
                     GEGGLRQLDLTWLRPSEPGSEGDYMVLPRRTLSLQPGGGGTGGEEAPRARPEGTPRRA
                     AKTVAHTEGYPSFLSVEHSGLGLGPAYGSLQNPYGMTFQPPPPTPSARQVPEPGERSR
                     TMPRTVPGSTMKLGSLERKKLRYSDLDFEKVMHTRKRHSELYHELNQKFHTFDRYRSQ
                     SSAKEKPSPPGGRPGLSQHRRHQSWSTFKSMTLGSLPPKPRERLALHRTAAWEPTEPP
                     DGDFQTEV"
     exon            824..907
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1072
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            1073..1237
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1402
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..1570
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1672
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            1673..1779
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            1780..1974
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            1975..2043
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            2044..2152
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            2153..2489
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            2490..2595
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            2596..2639
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            2640..2766
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            2767..2870
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..2973
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            2974..3124
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            3125..3194
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            3195..3261
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            3262..3347
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            3348..3446
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            3447..3618
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            3619..3714
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            3715..3754
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            3755..4374
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            4375..4410
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            4411..4509
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
     exon            4510..5001
                     /gene="Adgrb2"
                     /gene_synonym="Bai2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcaagggac ataggatgac cccagcctgt cccctcttac tgtctgtgat tctgtccctg
       61 cgcctggcca cggccttcga ccctgccccc agtgcctgct ctgccctggc ctcgggcgtg
      121 ctctacgggg ccttctcact gcaggacctc tttcccacca tcgcctcggg ctgctcctgg
      181 accctggaga acccagaccc caccaagtac tcgctctacc tgcgcttcaa ccgacaggag
      241 caggtgtgca cacactttgc cccgcgcctg ctgcccctgg accactacct ggtcaacttt
      301 acgtgtctgc ggcctggtcc ggaggaagcc acagcccggg cggaatcaga agtggggcgg
      361 ccagaggagg aagcggaggc cgaggcagca gccacgggct tggagctgtg tggtggctca
      421 ggccctttca cctttctgca cttcgacaag aacttcgtgc agctgtgcct gtcggctgag
      481 ccctcggagg ccccacgtct gctagcgcct gctgccctgg ccttccgctt tgtggaggtt
      541 ttgcttatca acaacaacaa ctccagccag ttcacctgcg gcgtgctctg ccgctggagt
      601 gaggagtgtg gtcgggctgc aggcagggct tgtggctttg ctcagccagg gtgtagctgc
      661 cctggggagg ctggggccag ccctgccacc accacacctc cggggcctcc agctgcccac
      721 accctgtcca atgccttggt gcctgggggc ccagcccctc ctgctgaggc cgacttgcac
      781 tcggggagca gcaatgacct gttcaccacc gagatgagat acggtgagga gccggaagag
      841 gaaccgaagg tgaaaaccca gtggccaagg tctgcagatg agcctgggct atacatggcg
      901 cagacaggcg acccagcagc tgaggagtgg tccccgtgga gcgtgtgttc cctgacgtgt
      961 gggcagggtc tgcaggtgcg gacccgctcc tgcgtgtcct ccccctatgg gaccctgtgc
     1021 agcgggcccc ttcgggagac ccggccttgc aacaattcag ccacctgccc agtgcacggc
     1081 gtgtgggagg agtgggggtc ctggagcctg tgctcccgca gctgcgggcg ggggtcccgg
     1141 agtcggatgc ggacctgcgt gcccccccag cacggcggca aggcctgcga gggtcccgag
     1201 ctgcagacta aactctgcag tatggccgcc tgcccggtgg aaggccagtg gctagaatgg
     1261 ggtccctggg gcccatgctc ctcatcttgt gccaatggga cccagcagcg cagccggaag
     1321 tgcagtgtgg ccggtccagc ctgggccacg tgcgcaggtg ccctcaccga tacccgtgag
     1381 tgcagcaact tcgactgtcc agccactgat ggcaagtggg ggccatggaa cgcatggagc
     1441 ctgtgctcca agacgtgtga cacgggctgg caacgccgct tccgcatgtg ccaggcttcc
     1501 ggcacgcagg gctacccttg cgagggcacg ggagaggagg tgaaaccctg cagtgagaag
     1561 aggtgtccag ccttccatga gatgtgcaga gacgagtacg tcatgctcat gacgtggaag
     1621 agggcagcgg ctggcgagat catttacaac aaatgtcccc ctaatgcctc gggttctgct
     1681 agccgccgct gtctcctcag tgcccagggc gtggcatact ggggactgcc cagtttcgct
     1741 cgttgtatat ctcatgaata ccgatacctg tacctgtcac ttcgggagca cctggctaag
     1801 ggccagcgca tgctggcagg tgagggcatg tcgcaggtgg tgcggagcct acaggagctc
     1861 ctggctcggc gtacttacta cagcggggac ctgctcttct ctgtggacat tctaaggaac
     1921 gtcactgaca ccttcaagag ggccacctat gtcccttccg ctgatgacgt gcagcgtttc
     1981 ttccaggtgg tgagctttat ggtggactca gaaaacaagg ataagtggga cgacgctcag
     2041 caggtgtcgc ctggctctgt gcacttgctg cgtgttgtgg aagatttcat tcacctcgtg
     2101 ggcgacgctc tcaaggcctt ccagagctct ctgattgtca cggacaacct ggtgatcagc
     2161 attcagagag agcctatctc agcggtgtcc agtgacatca catttcccat gcggggccgc
     2221 aggggcatga aggactgggt acgacattca gaggatcgcc tcttcctacc caaggaggtg
     2281 ctcagcctgt cctccccagg gaagccagcc acacctgggg cagccacagc gggcagcccg
     2341 ggcaggggga ggggcccagg aacggtgccc cctggcccag gccccgccca ccagcgcctt
     2401 ctcccagctg accccgaaga gtcctcctcc tactttgtga tcggtgctgt gctctaccgc
     2461 acccttggcc tcatcctgcc gccccccagg cctccacttg ctgtcacctc ccgggtgatg
     2521 acagtgactg tgcgtccccc cacccagcct ccagcggagc ccctcattac agtagagctc
     2581 tcgtacatca tcaatggcac cactgatccc cactgtgcca gctgggacta ctcgagagca
     2641 gatgccagct tgggggactg gaacactgag agctgccaga ccttggagac ccaagcagct
     2701 cacacccgct gccagtgcca gcacctgtcc acctttgccg tcctggccca gccacccaag
     2761 gacctgactc tggagctggc gggtgctccc tctgtccccc tggtgatcgg ctgtgcggtg
     2821 tcctgcatgg ccctgctcac gttgctggcc atctatgcag ccttctggag gtttataaag
     2881 tcagaacgct ccatcatctt gctgaacttc tgcctgtcca tcctggcttc caacatcctg
     2941 atcctcgtgg gccagtcccg ggtgctgagc aagggcgtat gcaccatgac agctgccttc
     3001 ctacacttct tctttctgtc ctccttttgc tgggtgctta cagaggcctg gcaatcctat
     3061 ctggctgtca tcgggcggat gcgcacccgc ctggttcgca agcgcttcct ctgcctgggc
     3121 tggggtctgc ctgccctggt ggtggctgtg tctgttggct ttactcgcac caaaggatac
     3181 ggcacatcca gctactgctg gctgtcccta gagggtggcc tgctctacgc ctttgtgggt
     3241 ccagcagcag tcatcgtcct ggtgaacatg ctcatcggaa tcatcgtctt caacaagctc
     3301 atggctcgag atggcgtctc agacaagtct aagaagcaga gggccgggtc ggagcggtgc
     3361 ccctgggcca gcctgctcct cccctgctca gcgtgtggag cggtccccag ccccctgctc
     3421 agctcagcct cggccaggaa tgccatggct tccctctgga gttcctgcgt ggtactgcct
     3481 ctcctggcgc ttacctggat gtccgctgtc ctggccatga cagatcgccg ctccgtcctc
     3541 ttccaggcgc tctttgctgt tttcaactct gcacaaggct ttgtcatcac cgccgtgcac
     3601 tgcttcctgc gccgagaggt ccaggatgtg gtaaagtgcc agatgggtgt gtgtcggact
     3661 gatgagagtg aagactcccc agactcgtgc aagaacggac agctgcagat cctgtcagac
     3721 tttgaaaagg acgtggatct ggcttgtcag acagttctgt tcaaggaggt caacacttgc
     3781 aacccgtcca ccatcaccgg cactttgtcc cgcctgtctc tggatgagga tgaggagccc
     3841 aagtcctgtc tcgtgggtcc tgagggtggc ctcagcttct caccactgcc tgggaacatc
     3901 ctagtaccca tggcagcctc gccaggtctg ggggagccac caccaccaca ggagaccaac
     3961 cctgtgtaca tgtgtgggga gggtggcctg cggcaattgg accttacatg gctacggcca
     4021 agtgaaccag gctctgaggg ggactacatg gtgctgcccc ggcggacttt gagcctgcag
     4081 cctggcggtg ggggtacagg gggtgaggag gcaccaaggg cccggcctga ggggaccccc
     4141 cggcgggctg ccaagacagt ggcccacact gaaggctacc ccagcttctt gtctgtggag
     4201 cactcgggtc tagggctggg ccctgcctat gggtctctcc agaacccata tgggatgacc
     4261 ttccaaccac caccaccaac acccagcgcc cgccaagtac cagagccagg agaacgtagc
     4321 cggaccatgc cccgtacagt gcctggttcc accatgaagc tgggctccct tgagcgaaag
     4381 aagcttcggt attctgactt ggactttgag aaggtgatgc atacccggaa acggcactcg
     4441 gaactctacc acgaactcaa ccagaagttc cacactttcg accgctaccg tagccagtcc
     4501 tcagccaagg agaaacccag cccccctggg ggacgccctg gcttgtccca gcacaggagg
     4561 catcaaagct ggagcacttt caaatctatg acactgggct cactgccccc caaacctcga
     4621 gaacggctgg ctctgcaccg gacagcagcc tgggagccca cagaaccgcc agacggcgac
     4681 ttccagacag aggtgtgagt gccacgccgg actgcccact gcacagaaat atatatctat
     4741 tttcacactc cactttggaa ctaccaggag ccagcgcccc tccccctccc gaggctgggc
     4801 aggaggtgca gaggactcag cctggctggg ggcagccaga ctggcagggc ctgggggcca
     4861 gggcccctcc tggttctcag aggtccctta gccactcacc agagcctcat ctttgcccca
     4921 gcctgtctgt ccctgtcctg ggctggggag gggggaggga aactttgttg ggaataaact
     4981 tcactctgtg gatttgcctg c
//
