LOCUS       NM_001170597            6002 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Rattus norvegicus adhesion G protein-coupled receptor B1 (Adgrb1),
            mRNA.
ACCESSION   NM_001170597 XM_001073400 XM_039079535 XM_343260
VERSION     NM_001170597.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6002)
  AUTHORS   Billings,E.A., Lee,C.S., Owen,K.A., D'Souza,R.S., Ravichandran,K.S.
            and Casanova,J.E.
  TITLE     The adhesion GPCR BAI1 mediates macrophage ROS production and
            microbicidal activity against Gram-negative bacteria
  JOURNAL   Sci Signal 9 (413), ra14 (2016)
   PUBMED   26838550
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6002)
  AUTHORS   Zhu,D., Li,C., Swanson,A.M., Villalba,R.M., Guo,J., Zhang,Z.,
            Matheny,S., Murakami,T., Stephenson,J.R., Daniel,S., Fukata,M.,
            Hall,R.A., Olson,J.J., Neigh,G.N., Smith,Y., Rainnie,D.G. and Van
            Meir,E.G.
  TITLE     BAI1 regulates spatial learning and synaptic plasticity in the
            hippocampus
  JOURNAL   J Clin Invest 125 (4), 1497-1508 (2015)
   PUBMED   25751059
REFERENCE   3  (bases 1 to 6002)
  AUTHORS   Meisen,W.H., Dubin,S., Sizemore,S.T., Mathsyaraja,H., Thies,K.,
            Lehman,N.L., Boyer,P., Jaime-Ramirez,A.C., Elder,J.B., Powell,K.,
            Chakravarti,A., Ostrowski,M.C. and Kaur,B.
  TITLE     Changes in BAI1 and nestin expression are prognostic indicators for
            survival and metastases in breast cancer and provide opportunities
            for dual targeted therapies
  JOURNAL   Mol Cancer Ther 14 (1), 307-314 (2015)
   PUBMED   25376607
REFERENCE   4  (bases 1 to 6002)
  AUTHORS   Das,S., Sarkar,A., Ryan,K.A., Fox,S., Berger,A.H., Juncadella,I.J.,
            Bimczok,D., Smythies,L.E., Harris,P.R., Ravichandran,K.S.,
            Crowe,S.E., Smith,P.D. and Ernst,P.B.
  TITLE     Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes
            during infection with Helicobacter pylori and mediates the
            recognition and engulfment of human apoptotic gastric epithelial
            cells
  JOURNAL   FASEB J 28 (5), 2214-2224 (2014)
   PUBMED   24509909
REFERENCE   5  (bases 1 to 6002)
  AUTHORS   Um,J.W., Pramanik,G., Ko,J.S., Song,M.Y., Lee,D., Kim,H.,
            Park,K.S., Sudhof,T.C., Tabuchi,K. and Ko,J.
  TITLE     Calsyntenins function as synaptogenic adhesion molecules in concert
            with neurexins
  JOURNAL   Cell Rep 6 (6), 1096-1109 (2014)
   PUBMED   24613359
  REMARK    Erratum:[Cell Rep. 2024 Aug 27;43(8):114646. doi:
            10.1016/j.celrep.2024.114646.. PMID: 39110596]
REFERENCE   6  (bases 1 to 6002)
  AUTHORS   Kaur,B., Brat,D.J., Devi,N.S. and Van Meir,E.G.
  TITLE     Vasculostatin, a proteolytic fragment of brain angiogenesis
            inhibitor 1, is an antiangiogenic and antitumorigenic factor
  JOURNAL   Oncogene 24 (22), 3632-3642 (2005)
   PUBMED   15782143
REFERENCE   7  (bases 1 to 6002)
  AUTHORS   Kaur,B., Brat,D.J., Calkins,C.C. and Van Meir,E.G.
  TITLE     Brain angiogenesis inhibitor 1 is differentially expressed in
            normal brain and glioblastoma independently of p53 expression
  JOURNAL   Am J Pathol 162 (1), 19-27 (2003)
   PUBMED   12507886
REFERENCE   8  (bases 1 to 6002)
  AUTHORS   Duda,D.G., Sunamura,M., Lozonschi,L., Yokoyama,T., Yatsuoka,T.,
            Motoi,F., Horii,A., Tani,K., Asano,S., Nakamura,Y. and Matsuno,S.
  TITLE     Overexpression of the p53-inducible brain-specific angiogenesis
            inhibitor 1 suppresses efficiently tumour angiogenesis
  JOURNAL   Br J Cancer 86 (3), 490-496 (2002)
   PUBMED   11875720
REFERENCE   9  (bases 1 to 6002)
  AUTHORS   Lee,J.H., Koh,J.T., Shin,B.A., Ahn,K.Y., Roh,J.H., Kim,Y.J. and
            Kim,K.K.
  TITLE     Comparative study of angiostatic and anti-invasive gene expressions
            as prognostic factors in gastric cancer
  JOURNAL   Int J Oncol 18 (2), 355-361 (2001)
   PUBMED   11172604
REFERENCE   10 (bases 1 to 6002)
  AUTHORS   Fukushima,Y., Oshika,Y., Tsuchida,T., Tokunaga,T., Hatanaka,H.,
            Kijima,H., Yamazaki,H., Ueyama,Y., Tamaoki,N. and Nakamura,M.
  TITLE     Brain-specific angiogenesis inhibitor 1 expression is inversely
            correlated with vascularity and distant metastasis of colorectal
            cancer
  JOURNAL   Int J Oncol 13 (5), 967-970 (1998)
   PUBMED   9772287
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On or before Dec 16, 2022 this sequence version replaced
            XM_039079535.1, NM_001170597.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760389, SAMEA5760393
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-461               JAXUCZ010000007.1  108293818-108294278
            462-1460            JAXUCZ010000007.1  108306444-108307442
            1461-1622           JAXUCZ010000007.1  108315607-108315768
            1623-1733           JAXUCZ010000007.1  108316498-108316608
            1734-1898           JAXUCZ010000007.1  108317003-108317167
            1899-2063           JAXUCZ010000007.1  108317322-108317486
            2064-2237           JAXUCZ010000007.1  108317747-108317920
            2238-2402           JAXUCZ010000007.1  108318596-108318760
            2403-2504           JAXUCZ010000007.1  108318860-108318961
            2505-2611           JAXUCZ010000007.1  108320340-108320446
            2612-2806           JAXUCZ010000007.1  108320598-108320792
            2807-2875           JAXUCZ010000007.1  108321370-108321438
            2876-2984           JAXUCZ010000007.1  108322070-108322178
            2985-3128           JAXUCZ010000007.1  108324662-108324805
            3129-3204           JAXUCZ010000007.1  108325301-108325376
            3205-3307           JAXUCZ010000007.1  108325555-108325657
            3308-3351           JAXUCZ010000007.1  108326994-108327037
            3352-3493           JAXUCZ010000007.1  108340349-108340490
            3494-3597           JAXUCZ010000007.1  108346236-108346339
            3598-3700           JAXUCZ010000007.1  108347875-108347977
            3701-3851           JAXUCZ010000007.1  108348770-108348920
            3852-3921           JAXUCZ010000007.1  108349514-108349583
            3922-3988           JAXUCZ010000007.1  108350823-108350889
            3989-4074           JAXUCZ010000007.1  108352510-108352595
            4075-4246           JAXUCZ010000007.1  108357419-108357590
            4247-4342           JAXUCZ010000007.1  108359300-108359395
            4343-4382           JAXUCZ010000007.1  108360785-108360824
            4383-5080           JAXUCZ010000007.1  108363110-108363807
            5081-5116           JAXUCZ010000007.1  108364455-108364490
            5117-5224           JAXUCZ010000007.1  108364653-108364760
            5225-6002           JAXUCZ010000007.1  108365115-108365892
FEATURES             Location/Qualifiers
     source          1..6002
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..6002
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /note="adhesion G protein-coupled receptor B1"
                     /db_xref="GeneID:362931"
                     /db_xref="RGD:1305608"
     exon            1..461
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            462..1460
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     CDS             689..5422
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /note="brain-specific angiogenesis inhibitor 1"
                     /codon_start=1
                     /product="adhesion G protein-coupled receptor B1
                     precursor"
                     /protein_id="NP_001164068.2"
                     /db_xref="GeneID:362931"
                     /db_xref="RGD:1305608"
                     /translation="MRGQAAAPGPIWILAPLLLLLLLLGRWARAASGADIGPGTEQCT
                     TLVQGKFFGYFSAAAVFPANASRCSWTLRNPDPRRYTLYMKVAKAPAPCSGPGRVRTY
                     QFDSFLESTRTYLGVESFDEVLRLCDPSAPLAFLQASKQFLQMQRQQPPQDGDLGPQG
                     SGDDFSVEYLVVGNRNPSHAACQMLCRWLDACLAGSRSSHPCGIMQTPCACLGGEAGD
                     TASSPLVPRGDVCLRDGVAGGPENCLTSLTQDRGGHGSAGGWKLWSLWGECTRDCGGG
                     LQTRTRTCSPTLGVEGRGCEGVLEEGRLCNRKACGPTGRTSSRSQSLRSTDARRREEF
                     GDELQQFGFPSPQTGDPAAEEWSPWSVCSSTCGEGWQTRTRFCVSSSYSTQCSGPLRE
                     QRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEGPEKQTK
                     FCNIALCPGRAVDGNWNEWSSWSTCSASCSQGRQQRTRECNGPSYGGAECQGHWVETR
                     DCFLQQCPVDGKWQAWASWGSCSVTCGGGSQRRERVCSGPFFGGAACQGPQDEYRQCG
                     AQRCPEPHEICDEDNFGAVVWKETPAGEVAAVRCPRNATGLILRRCELDEEGIAFWEP
                     PTYIRCVSIDYRNIQMMTREHLAKAQRGLPGEGVSEVIQTLLEISQDGTSYSGDLLST
                     IDVLRNMTEIFRRAYYSPTPGDVQNFVQIISNLLAEENRDKWEEAQLMGPNAKELFRL
                     VEDFVDVIGFRMKDLRDAYQVTDNLVLSIHKLPASGATDISFPMKGWRATGDWAKVPE
                     DRVTVSKSVFSTGLAEADDSSVFVVGTVLYRNLGSFLALQRNTTVLNSKVISVTVKPP
                     PRSLLTPLEIEFAHMYNGTTNQTCILWDETDGPSSSAPPQLGPWSWRGCRTVPLDALR
                     TRCLCDRLSTFAILAQLSADATMDKVTVPSVTLIVGCGVSSLTLLMLVIIYVSVWRYI
                     RSERSVILINFCLSIISSNALILIGQTQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAW
                     QSYMAVTGRLRSRLVRKRFLCLGWGLPALVVAISVGFTKAKGYSTMNYCWLSLEGGLL
                     YAFVGPAAAVVLVNMVIGILVFNKLVSKDGITDKKLKERAGASLWSSCVVLPLLALTW
                     MSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQDAVKCRVVDRQEEGNG
                     DSGGSFQNGHAQLMTDFEKDVDLACRSVLNKDIAACRTATITGTFKRPSLPEEEKMKL
                     AKGPPPTFNSLPANVSKLHLHGSPRYPGGPLPDFPNHSLTLKKDKAPKSSFIGDGDIF
                     KKLDSELSRAQEKALDTSYVILPTATATLRPKPKEEPKYSINIDQMPQTRLIHLSMAP
                     DASFPTRSPPAREPPGGAPPEVPPVQPPPPPPPPPPPQQPIPPPPSLEPAPPSLGDTG
                     EPSAHPGPSSGAGTKNENVATLSVSSLERRKSRYAELDFEKIMHTRKRHQDMFQDLNR
                     KLQHAAEKEKEVPGVDNKPEKQQTPNKRAWESLRKPHGTPAWVKKELEPLPPSPLELR
                     SVEWEKAGATIPLVGQDIIDLQTEV"
     exon            1461..1622
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            1623..1733
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            1734..1898
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            1899..2063
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..2237
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            2238..2402
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            2403..2504
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            2505..2611
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            2612..2806
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            2807..2875
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            2876..2984
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            2985..3128
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            3129..3204
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            3205..3307
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            3308..3351
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            3352..3493
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            3494..3597
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            3598..3700
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            3701..3851
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            3852..3921
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            3922..3988
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            3989..4074
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            4075..4246
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            4247..4342
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            4343..4382
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            4383..5080
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            5081..5116
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            5117..5224
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
     exon            5225..6002
                     /gene="Adgrb1"
                     /gene_synonym="Bai1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaagagcc gggcaggcga gaggaccgga gcggcggcgc ggccggagag ggagcggcgg
       61 gcgcaggcgg tggtggcggc ggcggcggcg ggcgcggcgt tggcggcggc cccggcagag
      121 cgagctgagc gggcgagccg gcggcacaag cgtccgcgcc gcgtcctggc ccgactccgg
      181 gcccgcgcgc ctagcacaac ccgcagccag ggcatctgga cccctctggc gcccgggggg
      241 ctccgccagg cagggggtgg ggaggagcct gagagcgccc gcgggtgcgc tcttgggaac
      301 gtctcggcgg ggcccaaaga gagtcggggg cggcagcgac agtagcccca gctcggatcg
      361 ggcgcgcggc tcggcggctg gcgacgcggt gcgctccggg ggctttgcaa gtcgctggat
      421 caagtccttg ctcgcccgtg gggcctctgc tgctggggaa gctaccattg gaagccacag
      481 gcaagcacca ggaacctgga ctttaggagt cattgctggt ctcactgtct cctgaaaccc
      541 tgccctgtcc ccaccttgcc ttcacccagc ccctgcctct ggctcactgc cctggacggc
      601 cctgcctgct gccggaccct ggcatgtcaa ggcctggcct gcacttgcct gcccagcccg
      661 cggaacccca gcggccccgc gagctaggat gaggggccag gctgctgccc cgggccccat
      721 ctggatcctt gctccactcc tgctgttact attgctactg gggcgctggg cacgtgctgc
      781 ctctggggca gacatagggc ctgggacaga gcagtgcacc acattggtgc agggcaagtt
      841 cttcggatac ttctccgcgg ctgctgtgtt tccagccaac gcctcacgct gctcttggac
      901 tcttcgcaac ccggaccctc gtcgttacac gctctacatg aaggtggcca aggcacctgc
      961 accctgcagc ggccctggcc gagttcgcac ctaccagttc gactctttct tggaatccac
     1021 gcgcacctac ctgggtgtgg agagctttga cgaagttctg cggctctgcg atccctctgc
     1081 acccctagcc ttcctgcagg ccagcaaaca gttcctacag atgcagcgcc aacagccacc
     1141 ccaagatggt gaccttggtc cccagggctc tggtgacgac ttctctgtgg agtacctggt
     1201 ggtgggcaat cgcaacccca gccacgctgc ctgtcagatg ctgtgccgtt ggctggatgc
     1261 ctgtctagct ggcagccgca gctcacaccc ctgtggcatc atgcagactc cctgtgcctg
     1321 cctgggtgga gaagctggag acactgcttc cagccccttg gtcccccgtg gggacgtctg
     1381 cttgagagac ggcgtagctg gtggccctga gaactgcctc accagcctga cccaggaccg
     1441 aggtgggcac ggctcagcag gtggctggaa actgtggtcc ttgtggggcg aatgtacgcg
     1501 ggactgcggg ggaggcctac aaactcgaac ccgcacttgc tcgcccaccc ttggcgtgga
     1561 gggcagaggc tgtgagggcg ttctggaaga aggccgcctg tgcaatcgca aggcctgcgg
     1621 tcccactggg cgcaccagct cacggagcca gtccctgagg tccacggatg cccggcgtcg
     1681 tgaggagttt ggggatgagc tgcaacagtt tgggttccca tccccccaga ctggtgaccc
     1741 agcagctgag gagtggtccc catggagcgt atgctccagc acctgtggcg agggatggca
     1801 gacccgtacg cgcttctgcg tgtcatcctc gtacagtact cagtgcagtg gacctctgag
     1861 ggagcagcgg ctctgcaaca actcagcagt gtgtccagtg catggagcct gggatgagtg
     1921 gtcaccctgg agcctctgct ccagtacctg tggccgtggc ttccgtgacc gtactcgcac
     1981 ttgcaggccc cctcagtttg gaggcaaccc ctgtgagggt ccggagaagc aaaccaagtt
     2041 ctgcaacatt gccctgtgcc ctggccgggc agtggacgga aactggaatg aatggtccag
     2101 ctggagcacc tgctctgcca gttgctccca aggccgccag caacggaccc gggagtgcaa
     2161 tggtccttcc tatgggggtg ccgagtgcca gggccactgg gtggagactc gagactgctt
     2221 cctgcagcaa tgcccagtgg acggcaaatg gcaggcctgg gcatcatggg gcagctgcag
     2281 cgtcacgtgt ggaggtggaa gccagcgacg ggagcgtgtc tgctctggac ctttctttgg
     2341 gggagcagcc tgccagggcc cccaagatga gtaccgacag tgtggcgctc agcgatgtcc
     2401 cgagccccat gagatttgtg atgaggacaa ctttggggcc gtggtctgga aggagacccc
     2461 agctggagag gtggctgcag tccggtgtcc ccgcaatgcc acaggcctta tcctgcgccg
     2521 ctgtgagctg gacgaggagg gcatcgcctt ctgggagcca cccacctaca tccgctgtgt
     2581 ctccattgac taccggaaca tccagatgat gacccgagag cacctggcga aggcgcagcg
     2641 ggggctgcca ggggaggggg tctcagaggt catccagaca ctgctggaga tctcacagga
     2701 tggcaccagc tacagcggcg acctgctctc caccatcgat gtcctgagga acatgacaga
     2761 gatcttccgc agggcttact atagccccac acccggggat gtgcagaact ttgtccagat
     2821 catcagcaac ctgctggcgg aggagaaccg ggacaagtgg gaggaggcac agctgatggg
     2881 ccccaacgcc aaggagctct ttcgactggt ggaagacttt gtggatgtca tcggcttccg
     2941 catgaaggat ttgagggatg cctaccaggt gacagacaat ctggtgctca gcatccacaa
     3001 gcttccagcc agtggggcca ccgacatcag tttccctatg aagggctggc gtgccactgg
     3061 agactgggcc aaggtgccag aggacagggt caccgtgtcc aagagtgtgt tttccacagg
     3121 gctggcagaa gctgacgatt catctgtgtt cgtggttggt actgtgctct accggaactt
     3181 gggcagcttc ctagccctgc agaggaacac aactgtcctc aactctaagg tcatctccgt
     3241 gactgtgaag cccccacctc gatcgctcct cacacccttg gagatcgagt tcgcccacat
     3301 gtacaatggc accaccaacc agacttgtat cctgtgggat gagacagatg gaccctcctc
     3361 ctccgccccc ccgcagctcg ggccctggtc gtggcgcggc tgccgcacgg tgcccctcga
     3421 tgccctccgg acgcgctgcc tgtgtgaccg gctctccacc ttcgccatct tagcccagct
     3481 cagcgccgac gcgaccatgg ataaggtgac cgtgccatct gtgacgctca tcgtgggctg
     3541 tggcgtgtct tccctcaccc tgctcatgct ggtcatcatc tacgtgtctg tgtggaggta
     3601 cattcgctca gagcggtccg tcatcctcat caacttctgc ctgtccatca tctcctctaa
     3661 tgccctcatt ctcattgggc agacccagac ccgcaacaag gttgtgtgca cactggtggc
     3721 tgcctttttg cacttcttct tcctgtcctc attctgctgg gtgctcaccg aggcctggca
     3781 atcctacatg gctgtcaccg gccgcctccg gagccggctc gtccgcaagc gctttctctg
     3841 cctgggctgg gggctccctg cgctggtggt ggccatttct gtgggattca ccaaggccaa
     3901 ggggtacagc accatgaact attgctggct ctccctggag gggggacttc tgtatgcctt
     3961 cgtgggaccg gctgctgcag ttgtgctggt gaacatggtg atcgggatcc tggtgttcaa
     4021 caagctcgtg tccaaggacg gcatcacgga caagaagctg aaggagcggg caggggcctc
     4081 cctgtggagc tcctgcgtgg tgctgccgct gctggcgctg acctggatgt ctgctgtgct
     4141 tgctgtcacc gaccgccgct ccgccctctt ccagatcctc ttcgctgtct tcgactcact
     4201 ggagggcttc gtcatcgtga tggtgcactg cattctgcga agagaggtcc aggatgctgt
     4261 gaagtgtcgt gtggtagatc gacaagagga gggcaacggg gactcggggg gctccttcca
     4321 gaacggccac gctcagctca tgaccgactt tgagaaggat gtggatctgg cctgtagatc
     4381 agtgctgaac aaagacattg cagcctgccg cacggcaact atcacaggta ccttcaagcg
     4441 accatcactg cctgaagagg agaagatgaa gctggccaag ggcccacccc ccaccttcaa
     4501 cagcctacca gctaatgtgt ccaagctgca cctgcacggt tcaccccgct accccggtgg
     4561 gccactgcct gacttcccca accattcact cacccttaaa aaggacaagg cccccaagtc
     4621 ctcttttatt ggtgatgggg acatctttaa gaaactggac tctgagctga gccgggccca
     4681 ggagaaggct ctggacacga gctacgtgat cctgcccacg gccacggcca cactccggcc
     4741 caaacccaag gaggaaccca aatacagcat caacattgac cagatgcccc aaacccgact
     4801 catccacctt agcatggcgc ccgacgccag cttccctacc cgaagcccac ctgcccgtga
     4861 gcccccaggt ggtgcacccc ctgaggtgcc ccctgtccag ccaccaccac cacctccacc
     4921 accccctcca ccccaacagc ccataccccc accaccctcc ctggagcctg cacctcccag
     4981 cctgggggac acaggggagc cttcggccca cccaggaccc agttcaggtg ctgggaccaa
     5041 gaatgagaac gtggccacct tgtcagtgag ctccttggag cggcggaaat cacggtatgc
     5101 agaactggac ttcgagaaga tcatgcacac acggaagcga caccaggaca tgttccagga
     5161 cctgaaccgg aagctgcagc atgcggctga gaaggagaag gaggtgccag gcgtagacaa
     5221 caagccagag aagcagcaaa ctcccaacaa gagggcctgg gagagcctcc gcaagcccca
     5281 tgggacaccc gcttgggtaa agaaggagct ggagccactg cccccgtctc cattggagct
     5341 gcggagtgtg gagtgggaga aggcgggtgc caccatccca ctggttggcc aggacatcat
     5401 cgacctccag accgaggtct gagcgggcgg gccgtggccc cacaccgggc caggaggtgg
     5461 gatgctgctc tgcccgctcc gccataggac gggcacagat gcgctcgcgg tggcgggccg
     5521 ggtccagccc cggcctcagg gcgctcagag gcggccaggc agagggcccg cggtgctggg
     5581 accagagcca gacacaggac aggaggtggc atggccggcg ggcacaggga tccagaggcc
     5641 ggatggtgcc tcagactctg ccctccttgg gcaaccccgg gcaggcaggc aagcggctgt
     5701 ggacatggac aggcctggtg tggccagcgt ccccaggatg cccacctcag ccaccactgc
     5761 agaggactgc ctgcggccca ccagcctggc tccgattttt agataccccc taccccttgg
     5821 gaagcagcca gaccccccca ctcccttcca ggaccctggg cccctcccag acccaggcag
     5881 agagcatggt cctgacccag agccccccgg ggcaggactg agaccactct ggaaagaagc
     5941 agggtgggga atctattttt tctctccttt tcttttcttc aataaaaaga attaaaaacc
     6001 ca
//
