LOCUS       NM_133302               2720 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Rattus norvegicus adenosine deaminase RNA specific B2 (Adarb2),
            mRNA.
ACCESSION   NM_133302
VERSION     NM_133302.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2720)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   2  (bases 1 to 2720)
  AUTHORS   Melcher,T., Maas,S., Herb,A., Sprengel,R., Higuchi,M. and
            Seeburg,P.H.
  TITLE     RED2, a brain-specific member of the RNA-specific adenosine
            deaminase family
  JOURNAL   J Biol Chem 271 (50), 31795-31798 (1996)
   PUBMED   8943218
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U74586.1.
            
            On Aug 30, 2012 this sequence version replaced NM_133302.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U74586.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760384 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2720              U74586.1           2-2721
FEATURES             Location/Qualifiers
     source          1..2720
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.1"
     gene            1..2720
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /note="adenosine deaminase RNA specific B2"
                     /db_xref="GeneID:117088"
                     /db_xref="RGD:621519"
     exon            1..424
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /inference="alignment:Splign:2.1.0"
     CDS             325..2565
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /note="RNA-editing enzyme 2; RNA-editing deaminase 2;
                     dsRNA adenosine deaminase B2; RNA-dependent adenosine
                     deaminase 3; adenosine deaminase 3, RNA dependent"
                     /codon_start=1
                     /product="double-stranded RNA-specific editase B2"
                     /protein_id="NP_579836.1"
                     /db_xref="GeneID:117088"
                     /db_xref="RGD:621519"
                     /translation="MASVLGSGRGSGGLSSQLKCKSKRRRRRRSKRKDKVSILSTFLA
                     PFKYLSPGTTNTEDEDNLSTSSAEVKENRNVSNLGTRPLPPGDWARGGSTPSVKRKRP
                     LEEGNGGHFCKLQLIWKKLSWSMTPKNALVQLHELKPGLQYRMVSQTGPVHAPVFAVA
                     VEVNGLTFEGTGPTKKKAKMRAAEMALKSFVQFPNAFQAHLAMGSSTSPCTDFTSDQA
                     DFPDTLFKEFEPSSRNEDFPGCCPVDTEFLSSAYRRGRLLYHTLDLMGQALPDRSRLA
                     PGALGERNPVVVLNELRSGLRYVCLSETAEKPRVKSFVMAVCVDGRTFEGSGRSKKLA
                     KGQAAQAALQALFDIRLPGHIPSRSKSNLLPQDFADSVSQLVTQKFRELTVGLTSVYA
                     RHKTLAGIVMTKGLDTKQAQVIVLSSGTKCISGEHISDQGLVVNDCHAEIVARRAFLH
                     FLYTQLELHLSKHQEDPERSIFIRVKEGGYRLRENILFHLYVSTSPCGDARLNSPYEI
                     TIDLNSSKHIVRKFRGHLRTKIESGEGTVPVRGPSAVQTWDGILLGEQLVTMSCTDKI
                     ASWNVLGLQGALLCHFIEPVYLHSIIVGSLHHTGHLARVMSHRMEGIGQLPASYRQNR
                     PLLSGVSNAEARQPGKSPHFSANWVVGSADLEIINATTGKRSCGGSSRLCKHVFSARW
                     ARLHGRLSTRIPGHGDTPSMYCEAKRGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQD
                     QFLLSL"
     exon            425..511
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /inference="alignment:Splign:2.1.0"
     exon            512..1422
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /inference="alignment:Splign:2.1.0"
     exon            1423..1537
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1706
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1858
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /inference="alignment:Splign:2.1.0"
     exon            1859..2027
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /inference="alignment:Splign:2.1.0"
     exon            2028..2209
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /inference="alignment:Splign:2.1.0"
     exon            2210..2388
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /inference="alignment:Splign:2.1.0"
     exon            2389..2720
                     /gene="Adarb2"
                     /gene_synonym="Adar3; Red2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaagtagcag ccctgcttct ggagcccaga ggaagaggag agagctccag ggtgctcagg
       61 acgacacgcg ggaatatctt tcccagagct ttctgcctaa agaagggttc agctttccgg
      121 cgtgcatccg aggctttcag ctcaactgga accaagcgac gggacgatta tagagaaggt
      181 gcttgctggc gtgctcagtc ctaaaaagtg agactgctac ttgatttgca aaaccagaaa
      241 tactcccggc tgcggccgca gcagcaagac taagaaaggt gaaactgctt aaggaccggc
      301 tcctctctgg gtctcccgac tggcatggca tctgtcctgg ggagtggcag agggtctgga
      361 gggctaagca gtcagctcaa atgcaagtcc aagaggagaa ggaggagaag gtccaagagg
      421 aaagacaaag tcagcatact gtcaaccttc ctcgctcctt tcaagtacct aagtcctggc
      481 accacaaaca cggaggatga agacaatctg agtaccagca gtgctgaagt gaaagaaaac
      541 cgaaatgtga gcaaccttgg gaccaggccc ctgccccctg gagactgggc cagaggcggc
      601 agcacaccca gcgttaaaag gaaaaggccg ctggaggaag gaaatggggg acatttctgc
      661 aaactgcagc tgatctggaa aaaactctcc tggtctatga cacccaagaa tgcgctggtc
      721 cagctacatg agctgaagcc gggtcttcag taccggatgg tgtcacagac tggcccagtg
      781 cacgccccag ttttcgccgt ggctgtagaa gtaaacgggc tcacgtttga aggcacgggg
      841 cccactaaga agaaggccaa gatgcgggca gcagagatgg ccctgaagtc cttcgtgcag
      901 ttccccaatg cattccaggc ccacctggct atgggcagta gtaccagtcc gtgcactgac
      961 ttcacctctg accaagctga cttcccagac acgttgttca aggagttcga accatcctca
     1021 agaaacgagg atttcccggg ctgctgtccc gttgacactg agtttctgtc ctctgcctac
     1081 cggcgaggac ggctgctcta ccacacactg gacctcatgg gccaggctct gcctgacagg
     1141 tccaggctgg ctccaggggc actgggtgag agaaaccctg tagtggtgtt gaatgaatta
     1201 cgctcaggtc ttcggtatgt gtgcctctcc gagacagccg agaagccccg agtcaagagc
     1261 tttgtcatgg ctgtgtgcgt ggacgggagg acgttcgaag gctctggacg cagtaagaag
     1321 ctggccaagg gccaagcagc acaagctgcc ttgcaggccc tcttcgacat ccggctgcca
     1381 ggtcacatac ccagcaggag taaaagcaac ctcttgccac aggattttgc agactctgtg
     1441 tctcagctgg tcacacagaa gttccgtgaa ctgacagtcg gcctgacatc tgtgtatgcc
     1501 cgccacaaaa cactggcagg aatcgtcatg accaaaggct tggacaccaa acaagcacag
     1561 gtcatcgttc tgtcctctgg gaccaagtgt atcagcggtg agcacatcag tgaccagggg
     1621 ctggttgtca acgactgtca cgctgagatt gtggcaaggc gagcatttct tcacttcctc
     1681 tacactcagc tggagctgca cttgagcaag catcaagagg accccgagag atcaatattc
     1741 atccgtgtaa aggaaggagg ctacaggctg cgagaaaaca tcctcttcca cctctacgtg
     1801 agcacatccc cttgtggaga cgccagactc aactctccct atgaaatcac catagacttg
     1861 aacagcagca aacacatcgt caggaagttc cgagggcacc tgcgcaccaa gattgagtct
     1921 ggggaaggaa cagtccctgt gcggggcccc agtgcagtcc agacatggga tggcatcctg
     1981 ctgggggagc agctagtcac catgtcctgc acagacaaga ttgccagctg gaatgtgctg
     2041 ggactacaag gcgctctcct ctgtcacttc atcgagcctg tgtacctcca tagcatcatt
     2101 gtgggaagcc tgcatcacac gggccacctt gcacgggtca tgagccacag gatggagggc
     2161 atcggccaac tgcctgcctc ataccgacaa aacaggcctc tccttagtgg tgtgagtaac
     2221 gccgaggccc ggcagccagg aaagtctccc cacttcagtg ccaactgggt cgtaggcagt
     2281 gccgacctgg agatcattaa tgccacaact gggaagagga gctgtggggg ttcatcccgg
     2341 ctctgcaagc acgtgttttc tgctcggtgg gcacggctgc atggtaggct aagcacacgg
     2401 atcccaggcc acggagacac accctccatg tactgtgaag ccaagcgggg ggctcacacc
     2461 taccagtctg ttaaacagca gctcttcaag gcttttcaga aagctggtct tggcacctgg
     2521 gtgagaaagc caccagagca agatcagttt ctactaagtc tctaagttgc tagactcctt
     2581 ggctattgga ccagagtgag atgcccggag aggatgaagc cgtatgatgg tgtggtgtgt
     2641 ccatcagttc ttgacctttg ttctccttca ttgttcagga acacatggcc tcatgtgtgg
     2701 atgagagact acacttgagt
//
