LOCUS       XM_039103210            5923 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus adenosine deaminase, RNA-specific
            (Adar), transcript variant X4, mRNA.
ACCESSION   XM_039103210
VERSION     XM_039103210.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039103210.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5923
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5923
                     /gene="Adar"
                     /note="adenosine deaminase, RNA-specific; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 97 ESTs, 3 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     87 samples with support for all annotated introns"
                     /db_xref="GeneID:81635"
                     /db_xref="RGD:71099"
     CDS             216..3650
                     /gene="Adar"
                     /codon_start=1
                     /product="double-stranded RNA-specific adenosine deaminase
                     isoform X4"
                     /protein_id="XP_038959138.1"
                     /db_xref="GeneID:81635"
                     /db_xref="RGD:71099"
                     /translation="MEEAEAAGDCRGLHLFTGVFPHQTQPCLDPSYEHSKWRYLQPRG
                     SESYLRSFQLQQIEFLKGRLPEAPLIGAQTQSLPTFLPGHWPRFPGPPAQGKQPEIWG
                     FPRSVTLRNQGFHIGPPLPPPHSRGPPWRGAEGLCSHFQELSISQNPEQKVLNRLEEL
                     GEGKATTAYALARELRTPKKDINRILYSLERKGKLHRGVGKPPLWSLVPLSQACTQPP
                     RAVNSDKEVPRGEPDLDSEDGDPASDLEGPSELLDMAEIKEKICDYLFNVSKSSALNL
                     AKNIGLAKARDVNAVLIDLERQGDVYREGATPPIWYLTDKKRERLQMKRSTHSGPAAT
                     PAAVSEATQSTSFPTCHPPQSGGSSSMATSKRVENGQEPVTKYESRHEARPGPVRLRP
                     HAYHNGPSRAGPTLPRCSPYKKLTECQLKNPVSGLLEYAQFTSQTCDFNLIEQSGPSH
                     EPRFKFQVVINGREFPPAEAGSKKVAKQDAAVKAMAILLREAKAKDSGQPEELSNCPM
                     EEDPEKPAESQPPSSSATSLFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHDPKFQ
                     YCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKALQEEAANSADDQSGGANTDSLDESVA
                     PNKIRRIGELVRYLNTNPVGGLLEYARSHGFAAEFKLIDQSGPPHEPKFVYQAKVGGR
                     WFPAVCAHSKKQGKQDAADAALRVLIGESEKAEQLGFAEVTPVTGASLRRTMLLLSRS
                     PDAHPKTLPLTGSTFHDQIAMLSHRCFNALTNSFQPSLLGRKILAAIIMKRDPEDMGV
                     VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNHHTAKNSIFE
                     LARGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAVESTESRHYPVFENPKQGK
                     LRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFL
                     QPVYLKSVTLGYLFSQGHLTRAICCRVTRDGNAFEDGLRYPFIVNHPKVGRVSVYDSK
                     RQSGKTKETSVNWCLADGYDLEILDGTRGTVDGPGKELSRVSKKNIFLQFKKLCSFRA
                     RRDLLQLSYGEAKKAARDYDLAKNYFKKSLRDMGYGNWISKPQEEKNFYLCPVPND"
ORIGIN      
        1 aatctgcgcc ctaaccattg attcctgact gaaggtggag gactacgcgt tgggaccaac
       61 cggaaaagct gagactactg actgccctaa gtcatggctt tgtggctagc tgctttctag
      121 catggcagat cactcactgt ggacagaagg agaggagctc tggggctgga caggctgtct
      181 cctgggatgg cagtgcacac tgattctcta taaccatgga ggaagcagaa gcagcaggtg
      241 actgccgtgg gctccacttg tttacagggg tgttccctca ccagacacag ccctgcttgg
      301 accctagcta tgagcacagc aagtggagat acctgcagcc acgtgggtcg gagtcttacc
      361 ttaggagttt ccagctccag cagatagagt ttctcaaagg gcggctccca gaagcaccct
      421 tgattggagc acagacccag tcactaccga cattcctccc aggacactgg ccaaggttcc
      481 cagggccacc tgcccaagga aaacaaccgg aaatctgggg gtttcccagg agtgtgactc
      541 tcagaaatca ggggttccat ataggacccc cacttcctcc tccacacagc aggggtccgc
      601 catggagagg tgctgaaggt ctttgctcac acttccagga gctgagcatc agtcagaatc
      661 cagagcagaa ggtcctaaac cgcctggaag agcttggtga ggggaaggcc accactgcct
      721 acgcgctagc cagagagctc aggaccccca aaaaggacat caatcgtata ttgtactcct
      781 tagaaaggaa gggaaagctg catagaggag tggggaagcc tcctttgtgg agccttgtgc
      841 ccttaagtca ggcttgcact cagcccccta gagctgtgaa ttcagacaag gaagtccctc
      901 gaggagagcc cgatttggac agtgaggacg gagaccctgc ctctgactta gaaggacctt
      961 ctgagcttct tgatatggct gaaattaagg agaaaatctg tgactatctg ttcaatgtgt
     1021 caaagtcctc tgccctgaac ctggctaaga acattggcct cgccaaggcc cgagatgtga
     1081 atgcagtgtt gattgactta gaaaggcaag gcgatgtcta cagggaaggg gccactcctc
     1141 ccatctggta cttgacggac aagaagcgtg agaggctgca gatgaagaga agtacacaca
     1201 gtggtcctgc agctacccca gcagctgtct cagaagccac tcaaagcacc tcattcccta
     1261 cctgccaccc accccaatca ggtggctcaa gcagcatggc aacctccaaa agagtggaaa
     1321 acgggcagga gcctgtgaca aagtatgaaa gtaggcacga ggcccgacca ggaccagtac
     1381 gactgcggcc tcatgcttat cacaacggcc cctctagagc aggccctacc ttgccacggt
     1441 gttcacccta caagaagcta actgagtgcc agctgaagaa ccctgtcagc gggttgttag
     1501 agtatgctca gttcactagt cagacctgtg atttcaacct gatagagcag agtggaccgt
     1561 cccatgaacc tcgatttaaa ttccaggttg tcatcaatgg tcgagagttt cccccagctg
     1621 aggctggcag caagaaagtt gctaagcagg acgcagcagt gaaagccatg gcgattctgc
     1681 ttcgggaagc caaagccaaa gacagtggac agccagaaga attgtccaac tgtcccatgg
     1741 aggaagaccc agagaagcca gcagagtccc agccccccag ctcctcagca acatccttgt
     1801 tctctgggaa gagcccagtt actacactgc ttgagtgtat gcacaagcta gggaactcct
     1861 gtgaatttcg tctcctgtcc aaagaaggcc ctgctcatga ccccaagttc cagtactgtg
     1921 tggcagtagg agcccagact ttcccctctg tgagtgcccc cagcaagaaa gtagcaaagc
     1981 agatggccgc agaggaagcc atgaaagctc tgcaagagga ggcggccaat tccgctgatg
     2041 accagtctgg aggtgcgaac acagactcac ttgatgaatc tgtggctccc aacaagatcc
     2101 ggaggatcgg tgagctcgta aggtacctga acaccaaccc tgtgggtggc ttgttggagt
     2161 acgcccgctc tcatggcttt gctgctgagt tcaagctcat tgaccagtct ggacctcctc
     2221 atgaacccaa gtttgtttac caagcaaaag ttgggggccg ctggtttcca gccgtgtgtg
     2281 cacacagcaa gaaacagggc aagcaagacg cagcggatgc agcccttcgt gtcttgatcg
     2341 gggagagcga gaaggcagag cagttgggtt tcgcagaggt aaccccagta accggggcca
     2401 gtctcagaag aactatgcta ctcctttcca ggtccccaga tgcacatcca aagacacttc
     2461 ctctcactgg tagcaccttc cacgaccaga tagctatgct gagccacaga tgcttcaacg
     2521 ctctgaccaa cagtttccag ccctccctgc tcggccgcaa gatcctggct gctattatta
     2581 tgaagagaga tcctgaggac atgggtgttg ttgtcagttt ggggactggg aatcgctgtg
     2641 tgaaagggga ctctctcagc ctgaaaggag agactgtcaa tgactgccat gctgaaatca
     2701 tctcccggag aggcttcatc aggtttctct acagtgagct gatgaagtac aaccaccaca
     2761 ctgccaagaa cagcatattc gagctggcca ggggaggaga gaagctccag ataaaaaaga
     2821 cggtttcttt tcacctctac atcagcacgg caccatgtgg agatggagcc ctctttgaca
     2881 aatcctgcag tgaccgtgct gtggaaagca cagagtcccg ccattaccct gtctttgaaa
     2941 atcccaagca aggcaagctt cgcaccaagg tggagaatgg ggaaggcaca attcctgtgg
     3001 agtccagtga cattgtaccc acgtgggatg gcatccggct tggggaaaga ctccgtacca
     3061 tgtcctgtag tgacaaaatc ctacgctgga atgtgctagg cctgcaaggg gcgctgttga
     3121 cacacttcct acagcctgtg tacctgaaat ctgtgacatt aggttacctt ttcagccaag
     3181 ggcatctgac ccgtgctatt tgctgccgtg tgaccagaga tgggaatgca tttgaggatg
     3241 gactacgtta tccctttatt gtcaaccacc ccaaggtcgg ccgagtcagt gtgtatgatt
     3301 ccaaaaggca gtccggaaag accaaagaga caagcgtcaa ctggtgcttg gctgatggct
     3361 atgacctgga gatcctggat ggcaccaggg gcaccgtgga tggaccaggg aaagagttgt
     3421 cgcgggtgtc taagaagaat attttccttc agtttaagaa gctctgctcc ttccgagccc
     3481 gcagagattt gctgcagctc tcctatgggg aggccaagaa agctgcccgt gactacgact
     3541 tagccaagaa ctacttcaag aaaagcctga gggacatggg ctatgggaat tggatcagca
     3601 aaccccagga ggaaaagaac ttttatctct gtccagtgcc caatgactga tagtggggtg
     3661 tgttcccatg gggtcagagg gaggtcatag cattcctcat cacattgggc cagagtttag
     3721 gggccttttt taaccccctc ccccccattt tttaatggag aaaccataat agatggtaaa
     3781 gacctttggt tcccattaat cctgcttgct ttgggatttc gaggtggggt ctggccaagt
     3841 tcccacctcc cttttcccaa gggaagaggc cgagattaaa ggaagaggaa gcactaccat
     3901 tccacatgta gcatagacag ttcttgatca catggagcct gggccccttg ggcttagttc
     3961 tgtggagttt ttctcatctc cttttccttt gcttcactgg cctcttgtgg gtttgatccc
     4021 atccccatca gttctctgta aatcatgtca gggacttaat gatgtcacct gtagatgtgc
     4081 aggtccccgt tctgtccccc ttcctcctag gatgccttcc tgtgaggttt ctgcttaccc
     4141 accccagagg atagatagag gcaaacaaag gatgggtgaa ctgtttacaa gggcaggagt
     4201 cgaaaagtgt gtcaggggtt gtagggcaac aggaatgtgg taagatgtgg ttggacaggc
     4261 aaaccctacc tagtaatggg ccgtgctggc ccgccaaggc agttcccctc ctgggcagct
     4321 gggaagttgg aagtcagcca tgggactgag gaaggtgccc aagccgagca agacccagca
     4381 ggggcccaca aagcactgac cagagtgcat caccactcct cggaatgtag ctacaccgcc
     4441 atccgtcctc catggagcat ccccagaagc tggctctgtc ccccgtgggt atggggacac
     4501 aggccccagg gactggtgaa agccaaggac aagtcctgga gggcagatta tctttgtcca
     4561 gacggagcaa aagtaaatgc aaaacgtcaa cgttggtccg ttggggttct tctcatgcac
     4621 agatacagca gaagttgaca aagccttgta taaaattgtt tctaaaaagc cagaggtgtt
     4681 gattctgaac tgcatcgcag acttgagatg caaatatatt tttccattag tgaatgtact
     4741 tcattatatc agatagcttc agaagctggt tcacaggcag ggcacaaggc ctggaatctt
     4801 ctatcctgct cctttgagaa tcttcatata cataaaagtg ttgtagatgg cagggcaggc
     4861 tagcctccca ccctggggtg ggcttctttg actcctcccc ctctgacagt gatttgtggc
     4921 tatgtgggag ccttagtctt tgtagagtct gactctagcc tcaaatcaac cagacagttc
     4981 gaccctgctc cattctgccc ctccaggacc gagcccacct ctttcctctg aatgctgcgg
     5041 ctccctctgg agacagctgc cagtgtgctc agcagcttcc tgcactccct tgcttacgcc
     5101 tcagtgttgc ctggctcccc caccctccgg cccactgcca acagcaaaca tcacattcac
     5161 actaagtcta atgactactg cctactcaac ccatgatcaa atctggatcc cacaggaact
     5221 taggacttaa caatatactg gggatgtctg cacagcacca aatcatcctg cagaactgct
     5281 ggtgtctgca gaagcgagag cagcaccatg cttgtgtcag ctggaggcat gttaccttct
     5341 ggcacccgca tctgaagcag aaccactgtg gccccaagcc tggcaggaag ctttagatct
     5401 ggggtctaaa ggccagagac gttccctttg attcctaggg ttcctctggt cctttctggg
     5461 tattcacaca gacccctatc tagaaaactt gtggttctgg gttcctgtgg gtggaggaga
     5521 gcaaggtatc cctgtgctgt gtgtgcttgc tgaagcgagc cactggtatc tgcatcccac
     5581 cccacccctg cctccagtcc tgctggccaa gggcagagct cccactgtgt ttccttcacc
     5641 tttttgtgtg atctttaaaa agcagggcct ccctccacaa cgtctcttaa taatttctgt
     5701 agttgatttg tctgaactgt ggctgtcttg cattctttga ataatcacgt ttaagaattg
     5761 tcaatgcttg aaactatttc ctgtactcaa gttgaaggga ctttgttggc ctagtagggc
     5821 agtggccagg catagcctcc gcgctgtgat ggatgcagtc ccttcttgtg tccctataca
     5881 agtgacagta tacattcctc agaataaaaa cgctgaagca tca
//
