LOCUS       NM_001400963            2960 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus ADAMTS-like 5 (Adamtsl5), transcript variant 3,
            mRNA.
ACCESSION   NM_001400963
VERSION     NM_001400963.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2960)
  AUTHORS   Bader,H.L., Wang,L.W., Ho,J.C., Tran,T., Holden,P., Fitzgerald,J.,
            Atit,R.P., Reinhardt,D.P. and Apte,S.S.
  TITLE     A disintegrin-like and metalloprotease domain containing
            thrombospondin type 1 motif-like 5 (ADAMTSL5) is a novel
            fibrillin-1-, fibrillin-2-, and heparin-binding member of the
            ADAMTS superfamily containing a netrin-like module
  JOURNAL   Matrix Biol 31 (7-8), 398-411 (2012)
   PUBMED   23010571
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.24843.1,
                                           SRR26643288.28966.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                JAXUCZ010000007.1  10013955-10014011
            58-126              JAXUCZ010000007.1  10014722-10014790
            127-229             JAXUCZ010000007.1  10014933-10015035
            230-423             JAXUCZ010000007.1  10016086-10016279
            424-515             JAXUCZ010000007.1  10016379-10016470
            516-576             JAXUCZ010000007.1  10016696-10016756
            577-685             JAXUCZ010000007.1  10016863-10016971
            686-813             JAXUCZ010000007.1  10018138-10018265
            814-925             JAXUCZ010000007.1  10018812-10018923
            926-1012            JAXUCZ010000007.1  10019462-10019548
            1013-1176           JAXUCZ010000007.1  10019633-10019796
            1177-1375           JAXUCZ010000007.1  10019916-10020114
            1376-1447           JAXUCZ010000007.1  10020196-10020267
            1448-2960           JAXUCZ010000007.1  10020412-10021924
FEATURES             Location/Qualifiers
     source          1..2960
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..2960
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /note="ADAMTS-like 5"
                     /db_xref="GeneID:314626"
                     /db_xref="RGD:1305607"
     exon            1..57
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            58..126
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            127..229
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            230..423
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     CDS             292..1749
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 3; thrombospondin, type I domain containing 6;
                     ADAMTS-like protein 5"
                     /codon_start=1
                     /product="ADAMTS-like protein 5 isoform 2 precursor"
                     /protein_id="NP_001387892.1"
                     /db_xref="GeneID:314626"
                     /db_xref="RGD:1305607"
                     /translation="MAVHSDSADHCLLGTQCSLRPRLFPPLLFLLWILLSCDLRGAAQ
                     GPGEWTLWGSWSRCSSSCGRGVSVRRRHCVRLPEEELCWGDSHEYRVCQLPDCPPGAI
                     PFRDLQCSLYNGHPVLGTQKTYQWVPFHGAPNLCDLNCLAEGHAFYHSFGRVLDGTPC
                     TPGTQGLCVAGRCLSAGCDGLLGSGTLEDRCGLCGGANDSCLFVQRVFRDAGAFAGYW
                     NVTLIPEGARHIRVTQRSHNHLALVTRDGHYVLNGDGVLSLPGTYEAAGTRVVYTRSA
                     GPEETLQATGPTSQELLLQVLLREPNPGVHFEFWLPRERYGSFQAQVHALGWPLRQPQ
                     PREVEPQPAETTVVPEAIPARVASLAPDPCGPCPDSRGRAHRLLHYCGSDFVFQARVL
                     GRHRLAQETRYEVRVLLIYKNRSPLRSREYVWAPGHCPCPPLAPHREYLLATRRHVSP
                     DGTQDRLLLPQAGYARLWSPAEDSRVRLAARRCPV"
     exon            424..515
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            516..576
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            577..685
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            686..813
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            814..925
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1012
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1176
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1375
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..1447
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..2960
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtccctggg gcgacccagg gaagcttgga cgcattgcct tgggctctga gcaactgacc
       61 ctctgggcac cgcagcccgc actcctggct gatgagacca tgacgcacat gttggcagga
      121 ggccagggtc tcggagactc acggaccgag ttccgcgagt tttcactgca cagatgagga
      181 acctgaggcc tggaaaaacg gaatggtcgg ttcctggcca cccaggaaga gacaagagga
      241 cccagagagg tttggctacc atcgaagacc acacagtcag ccagggctga gatggcagtt
      301 cactccgatt ctgctgatca ctgcctcttg ggaacccagt gctccctcag accccgcctc
      361 ttcccgcctc ttctgttctt gctgtggatt ctcctgagct gtgatttgag gggtgctgct
      421 cagggtccgg gagagtggac gctctggggg tcttggagcc ggtgttccag ctcgtgtggt
      481 cggggcgtct cagtgcgcag acgccactgc gtccgacttc ctgaggagga actttgctgg
      541 ggggacagtc atgaataccg ggtgtgccag ctgccggact gccccccagg ggccatacca
      601 ttccgagacc tgcagtgttc tctctacaat ggccaccccg tcctgggcac ccagaaaacc
      661 tatcaatggg tgcccttcca cggggcgccc aatctgtgtg acctcaactg cctggctgaa
      721 ggccacgcct tctaccacag ctttggccgc gtgctggatg gcaccccctg caccccgggg
      781 acccagggtc tctgcgtggc aggccgctgt ctgagcgcag gctgtgacgg actactgggc
      841 tccggcaccc tcgaggaccg ctgcggcctc tgtggtggtg ctaacgactc ttgcctgttc
      901 gtgcagcgcg tgttccgcga cgccggtgcc ttcgccggct actggaacgt gactttgatc
      961 cccgagggcg ccaggcacat ccgcgtaaca cagcgcagcc acaaccacct ggcgctggtg
     1021 acccgcgacg ggcactacgt gctcaacggt gatggtgtgc tcagcctgcc tggcacctat
     1081 gaggccgcgg gcacccgcgt ggtttacacc cgcagtgcgg gtccggagga gactctgcag
     1141 gctaccgggc ccacctccca ggagctgttg ttgcaggtgc tgctgcggga gcccaacccg
     1201 ggcgtgcact tcgagttctg gctgccccga gagcgctatg gctccttcca ggctcaggtg
     1261 cacgctctgg gctggcccct gcgacagcct cagcctcggg aggtggagcc gcagcctgca
     1321 gagaccactg tggtccccga ggccatccct gcccgtgttg catccctggc accagacccc
     1381 tgcgggccat gccctgacag ccgtggtcgc gcacaccggc ttcttcacta ctgtggcagc
     1441 gactttgtgt tccaggcccg tgtgctgggc cgccaccgcc tggcccagga gacccgctac
     1501 gaggtgcggg tcctgctcat ctacaaaaac cgctcgcctc tgcgatctcg agagtatgtg
     1561 tgggcaccag gccactgccc atgcccacca ctggccccac atcgagaata cctgttggct
     1621 accaggcgac acgtcagccc tgatggcaca caggaccggc tactgctgcc tcaggctggc
     1681 tatgctcggc tttggagtcc tgcggaggac agccgagttc gactagctgc ccggcgttgt
     1741 ccagtgtaaa cccccacctc cggcggtcgg ggtcagcggg ttcctgttct ggtgtcctat
     1801 gactcaggaa agtctcccac ttggaagctc gtatatttta attcgggtct ccctgtgcgc
     1861 acaaccctgg ctggcctgga gctctctatg tagaccaggc tggccttgaa gtcacagaga
     1921 tccacctgcc tctgtctccc tagtgaattc tgggattaaa ggtgcactcc atatctgaga
     1981 actttaagga gcttcaagat cctgggctac ctttccttta aacaacttct gtttgtctct
     2041 tttcaaatta ctatttaagt tttacaaaaa catggaaaca aagaatgctg ccttccccct
     2101 cacgtgttga gctataggga ctccaagaca ctctaggagt ggcaggcact gtgcagacat
     2161 aagcccattc ccatcttttt ctgatctggc ccaacaccca acgcagtgcg ctcattatga
     2221 gaccaacaca agaagtctgg gaagttgggg tgcacaggaa ccgctggacc tccattcctc
     2281 tatgcaatgg gttcatttgc gcctttgtct atcatgggtg tctgtcctat agccacacag
     2341 caagctatcc ccagtggggt gtcctttaag gctatcccct ctgggttctg aatctgtcac
     2401 gtggtctaac cagttgcctc gcccctctgc ctcagttctc atctctgcct gtggacactt
     2461 agttctccaa tgaacagcta ttgagcaccg actgtatgtg aaagacccgg cggtccaggg
     2521 aggtgcagtg ctgtgccagg ataagcaggg gtcactttgt ctaacagggc tttctatggt
     2581 gcccaagagc tccccccaaa ccccacagtg tagctccaca gggacctgtg gagtccttgc
     2641 gccccctggt ggctggccgt ggattcccag gttgggagat ggtctgcagc aggcttcagg
     2701 gacttcactc agctataatg gcggccaatg tgacactaga gaccaggaca gggtcatccc
     2761 tgacagggtt cctgtgctga gcctcataaa caaggtggaa gttaagaggt ggtggcacat
     2821 gactttaccc cagcaccagg gaggcagagg cagatagatt tctgtgagtt cgaagccagc
     2881 ctggtctaca gagtgaatta caggacagtc agtgccatac agaaaaacct ggcctttaaa
     2941 aaaacaaaat caaaacaaaa
//
