LOCUS       NM_001400960            3276 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ADAMTS-like 5 (Adamtsl5), transcript variant 1,
            mRNA.
ACCESSION   NM_001400960
VERSION     NM_001400960.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3276)
  AUTHORS   Bader,H.L., Wang,L.W., Ho,J.C., Tran,T., Holden,P., Fitzgerald,J.,
            Atit,R.P., Reinhardt,D.P. and Apte,S.S.
  TITLE     A disintegrin-like and metalloprotease domain containing
            thrombospondin type 1 motif-like 5 (ADAMTSL5) is a novel
            fibrillin-1-, fibrillin-2-, and heparin-binding member of the
            ADAMTS superfamily containing a netrin-like module
  JOURNAL   Matrix Biol 31 (7-8), 398-411 (2012)
   PUBMED   23010571
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ224249.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN09345238
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                JAXUCZ010000007.1  10013955-10014011
            58-126              JAXUCZ010000007.1  10014722-10014790
            127-229             JAXUCZ010000007.1  10014933-10015035
            230-341             JAXUCZ010000007.1  10015642-10015753
            342-535             JAXUCZ010000007.1  10016086-10016279
            536-627             JAXUCZ010000007.1  10016379-10016470
            628-688             JAXUCZ010000007.1  10016696-10016756
            689-797             JAXUCZ010000007.1  10016863-10016971
            798-925             JAXUCZ010000007.1  10018138-10018265
            926-1144            JAXUCZ010000007.1  10018812-10019030
            1145-1328           JAXUCZ010000007.1  10019365-10019548
            1329-1492           JAXUCZ010000007.1  10019633-10019796
            1493-1691           JAXUCZ010000007.1  10019916-10020114
            1692-1763           JAXUCZ010000007.1  10020196-10020267
            1764-3276           JAXUCZ010000007.1  10020412-10021924
FEATURES             Location/Qualifiers
     source          1..3276
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..3276
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /note="ADAMTS-like 5"
                     /db_xref="GeneID:314626"
                     /db_xref="RGD:1305607"
     exon            1..57
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            58..126
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            127..229
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            230..341
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            342..535
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     CDS             404..2065
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; thrombospondin, type I domain containing 6;
                     ADAMTS-like protein 5"
                     /codon_start=1
                     /product="ADAMTS-like protein 5 isoform 1 precursor"
                     /protein_id="NP_001387889.1"
                     /db_xref="GeneID:314626"
                     /db_xref="RGD:1305607"
                     /translation="MAVHSDSADHCLLGTQCSLRPRLFPPLLFLLWILLSCDLRGAAQ
                     GPGEWTLWGSWSRCSSSCGRGVSVRRRHCVRLPEEELCWGDSHEYRVCQLPDCPPGAI
                     PFRDLQCSLYNGHPVLGTQKTYQWVPFHGAPNLCDLNCLAEGHAFYHSFGRVLDGTPC
                     TPGTQGLCVAGRCLSAGCDGLLGSGTLEDRCGLCGGANDSCLFVQRVFRDAGDCPIPP
                     HGLHLRSMVDRGPFNEFGSWEPRLLLIGQCVPVHPTTAHPCTCHRVPENLAALHPKLP
                     PASGAFAGYWNVTLIPEGARHIRVTQRSHNHLALVTRDGHYVLNGDGVLSLPGTYEAA
                     GTRVVYTRSAGPEETLQATGPTSQELLLQVLLREPNPGVHFEFWLPRERYGSFQAQVH
                     ALGWPLRQPQPREVEPQPAETTVVPEAIPARVASLAPDPCGPCPDSRGRAHRLLHYCG
                     SDFVFQARVLGRHRLAQETRYEVRVLLIYKNRSPLRSREYVWAPGHCPCPPLAPHREY
                     LLATRRHVSPDGTQDRLLLPQAGYARLWSPAEDSRVRLAARRCPV"
     exon            536..627
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            628..688
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            689..797
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            798..925
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1144
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1328
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1492
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1691
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            1692..1763
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
     exon            1764..3276
                     /gene="Adamtsl5"
                     /gene_synonym="Thsd6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtccctggg gcgacccagg gaagcttgga cgcattgcct tgggctctga gcaactgacc
       61 ctctgggcac cgcagcccgc actcctggct gatgagacca tgacgcacat gttggcagga
      121 ggccagggtc tcggagactc acggaccgag ttccgcgagt tttcactgca cagatgagga
      181 acctgaggcc tggaaaaacg gaatggtcgg ttcctggcca cccaggaaga gaacccacga
      241 ctggttccaa gcacccatgc cgtgttgtga gcaactggaa ctcagcttag ctcaaaggga
      301 gtcagtgcac ctggcatctt gtcgcgctgc cctacgcgca cagacaagag gacccagaga
      361 ggtttggcta ccatcgaaga ccacacagtc agccagggct gagatggcag ttcactccga
      421 ttctgctgat cactgcctct tgggaaccca gtgctccctc agaccccgcc tcttcccgcc
      481 tcttctgttc ttgctgtgga ttctcctgag ctgtgatttg aggggtgctg ctcagggtcc
      541 gggagagtgg acgctctggg ggtcttggag ccggtgttcc agctcgtgtg gtcggggcgt
      601 ctcagtgcgc agacgccact gcgtccgact tcctgaggag gaactttgct ggggggacag
      661 tcatgaatac cgggtgtgcc agctgccgga ctgcccccca ggggccatac cattccgaga
      721 cctgcagtgt tctctctaca atggccaccc cgtcctgggc acccagaaaa cctatcaatg
      781 ggtgcccttc cacggggcgc ccaatctgtg tgacctcaac tgcctggctg aaggccacgc
      841 cttctaccac agctttggcc gcgtgctgga tggcaccccc tgcaccccgg ggacccaggg
      901 tctctgcgtg gcaggccgct gtctgagcgc aggctgtgac ggactactgg gctccggcac
      961 cctcgaggac cgctgcggcc tctgtggtgg tgctaacgac tcttgcctgt tcgtgcagcg
     1021 cgtgttccgc gacgccggtg actgccccat cccgcctcac ggcctgcact tgaggagcat
     1081 ggtggacagg ggtcccttta acgagtttgg ctcctgggag ccaagactct tgctgattgg
     1141 acagtgcgtc ccagtgcatc ccaccacagc gcacccctgt acatgccacc gcgtcccaga
     1201 aaatcttgcc gcgctacacc ccaaactccc gcctgcctca ggtgccttcg ccggctactg
     1261 gaacgtgact ttgatccccg agggcgccag gcacatccgc gtaacacagc gcagccacaa
     1321 ccacctggcg ctggtgaccc gcgacgggca ctacgtgctc aacggtgatg gtgtgctcag
     1381 cctgcctggc acctatgagg ccgcgggcac ccgcgtggtt tacacccgca gtgcgggtcc
     1441 ggaggagact ctgcaggcta ccgggcccac ctcccaggag ctgttgttgc aggtgctgct
     1501 gcgggagccc aacccgggcg tgcacttcga gttctggctg ccccgagagc gctatggctc
     1561 cttccaggct caggtgcacg ctctgggctg gcccctgcga cagcctcagc ctcgggaggt
     1621 ggagccgcag cctgcagaga ccactgtggt ccccgaggcc atccctgccc gtgttgcatc
     1681 cctggcacca gacccctgcg ggccatgccc tgacagccgt ggtcgcgcac accggcttct
     1741 tcactactgt ggcagcgact ttgtgttcca ggcccgtgtg ctgggccgcc accgcctggc
     1801 ccaggagacc cgctacgagg tgcgggtcct gctcatctac aaaaaccgct cgcctctgcg
     1861 atctcgagag tatgtgtggg caccaggcca ctgcccatgc ccaccactgg ccccacatcg
     1921 agaatacctg ttggctacca ggcgacacgt cagccctgat ggcacacagg accggctact
     1981 gctgcctcag gctggctatg ctcggctttg gagtcctgcg gaggacagcc gagttcgact
     2041 agctgcccgg cgttgtccag tgtaaacccc cacctccggc ggtcggggtc agcgggttcc
     2101 tgttctggtg tcctatgact caggaaagtc tcccacttgg aagctcgtat attttaattc
     2161 gggtctccct gtgcgcacaa ccctggctgg cctggagctc tctatgtaga ccaggctggc
     2221 cttgaagtca cagagatcca cctgcctctg tctccctagt gaattctggg attaaaggtg
     2281 cactccatat ctgagaactt taaggagctt caagatcctg ggctaccttt cctttaaaca
     2341 acttctgttt gtctcttttc aaattactat ttaagtttta caaaaacatg gaaacaaaga
     2401 atgctgcctt ccccctcacg tgttgagcta tagggactcc aagacactct aggagtggca
     2461 ggcactgtgc agacataagc ccattcccat ctttttctga tctggcccaa cacccaacgc
     2521 agtgcgctca ttatgagacc aacacaagaa gtctgggaag ttggggtgca caggaaccgc
     2581 tggacctcca ttcctctatg caatgggttc atttgcgcct ttgtctatca tgggtgtctg
     2641 tcctatagcc acacagcaag ctatccccag tggggtgtcc tttaaggcta tcccctctgg
     2701 gttctgaatc tgtcacgtgg tctaaccagt tgcctcgccc ctctgcctca gttctcatct
     2761 ctgcctgtgg acacttagtt ctccaatgaa cagctattga gcaccgactg tatgtgaaag
     2821 acccggcggt ccagggaggt gcagtgctgt gccaggataa gcaggggtca ctttgtctaa
     2881 cagggctttc tatggtgccc aagagctccc cccaaacccc acagtgtagc tccacaggga
     2941 cctgtggagt ccttgcgccc cctggtggct ggccgtggat tcccaggttg ggagatggtc
     3001 tgcagcaggc ttcagggact tcactcagct ataatggcgg ccaatgtgac actagagacc
     3061 aggacagggt catccctgac agggttcctg tgctgagcct cataaacaag gtggaagtta
     3121 agaggtggtg gcacatgact ttaccccagc accagggagg cagaggcaga tagatttctg
     3181 tgagttcgaa gccagcctgg tctacagagt gaattacagg acagtcagtg ccatacagaa
     3241 aaacctggcc tttaaaaaaa caaaatcaaa acaaaa
//
