LOCUS       NM_001107877            7965 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ADAM metallopeptidase with thrombospondin type 1
            motif, 9 (Adamts9), mRNA.
ACCESSION   NM_001107877 XM_001076761 XM_232202
VERSION     NM_001107877.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7965)
  AUTHORS   Dancevic,C.M., Fraser,F.W., Smith,A.D., Stupka,N., Ward,A.C. and
            McCulloch,D.R.
  TITLE     Biosynthesis and expression of a disintegrin-like and
            metalloproteinase domain with thrombospondin-1 repeats-15: a novel
            versican-cleaving proteoglycanase
  JOURNAL   J Biol Chem 288 (52), 37267-37276 (2013)
   PUBMED   24220035
REFERENCE   2  (bases 1 to 7965)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   3  (bases 1 to 7965)
  AUTHORS   Kern,C.B., Wessels,A., McGarity,J., Dixon,L.J., Alston,E.,
            Argraves,W.S., Geeting,D., Nelson,C.M., Menick,D.R. and Apte,S.S.
  TITLE     Reduced versican cleavage due to Adamts9 haploinsufficiency is
            associated with cardiac and aortic anomalies
  JOURNAL   Matrix Biol 29 (4), 304-316 (2010)
   PUBMED   20096780
REFERENCE   4  (bases 1 to 7965)
  AUTHORS   Koo,B.H., Coe,D.M., Dixon,L.J., Somerville,R.P., Nelson,C.M.,
            Wang,L.W., Young,M.E., Lindner,D.J. and Apte,S.S.
  TITLE     ADAMTS9 is a cell-autonomously acting, anti-angiogenic
            metalloprotease expressed by microvascular endothelial cells
  JOURNAL   Am J Pathol 176 (3), 1494-1504 (2010)
   PUBMED   20093484
REFERENCE   5  (bases 1 to 7965)
  AUTHORS   Reid,M.J., Cross,A.K., Haddock,G., Allan,S.M., Stock,C.J.,
            Woodroofe,M.N., Buttle,D.J. and Bunning,R.A.
  TITLE     ADAMTS-9 expression is up-regulated following transient middle
            cerebral artery occlusion (tMCAo) in the rat
  JOURNAL   Neurosci Lett 452 (3), 252-257 (2009)
   PUBMED   19348733
  REMARK    GeneRIF: study indicates that ADAMTS-9 expression is modulated in
            response to cerebral ischaemia in vivo
REFERENCE   6  (bases 1 to 7965)
  AUTHORS   Silver,D.L., Hou,L., Somerville,R., Young,M.E., Apte,S.S. and
            Pavan,W.J.
  TITLE     The secreted metalloprotease ADAMTS20 is required for melanoblast
            survival
  JOURNAL   PLoS Genet 4 (2), e1000003 (2008)
   PUBMED   18454205
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 7965)
  AUTHORS   Somerville,R.P., Longpre,J.M., Jungers,K.A., Engle,J.M., Ross,M.,
            Evanko,S., Wight,T.N., Leduc,R. and Apte,S.S.
  TITLE     Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS
            subfamily related to Caenorhabditis elegans GON-1
  JOURNAL   J Biol Chem 278 (11), 9503-9513 (2003)
   PUBMED   12514189
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473957.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_232202.4, XM_001076761.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5756307, SAMEA5760384
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..7965
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..7965
                     /gene="Adamts9"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif, 9"
                     /db_xref="GeneID:312566"
                     /db_xref="RGD:1306889"
     exon            1..452
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     CDS             338..5980
                     /gene="Adamts9"
                     /note="A disintegrin and metalloproteinase with
                     thrombospondin motifs 9; a disintegrin-like and
                     metalloprotease (reprolysin type) with thrombospondin type
                     1 motif, 9"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 9 precursor"
                     /protein_id="NP_001101347.1"
                     /db_xref="GeneID:312566"
                     /db_xref="RGD:1306889"
                     /translation="MQLVSWATLLTLLVPDLVEMRSPDSAAAVRKDRLHPRQVKLLES
                     LSEYEIASPIRVNPLGEPFPTNVHFKRRRRSINSASDPWPAFASSSSSSSTSSQEHYR
                     LKAFGQQFLFNLTAHTGFIAPLFTVTLLGEPGVNQSKLYSEEEMELRHCFYKGHVNTK
                     SEHTAVISLCSGMMGTFRSHDGDYFIEPLLSVDEQEDEEEQNKPHVIYRRNNPQREPS
                     TGKHACDTSELKNSYSKDKRKTRLRKRRKRNSLADDVAALKRGMATKAFSGYNNRTNG
                     TRDRRNHKRTKRFLSYPRFVEVMVVADHRMVLYHGSNLQHYILTLMSIVASIYKDSSI
                     GNLINIVIVNLVVIHNEQEGPSINFNAQTTLKNFCQWQHSKNHLGGIQHDTAVLVTRE
                     DICRAQDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHDDSNK
                     CKEEGVKSPQHVMAPTLNFYTNPWMWSKCSRKYITEFLDTGYGECLLNEPQSRTYPLP
                     SQLPGLLYNVNKQCELIFGPGSQVCPYMHCKFGFCVPKEMEGPAIDGSWGSWSHFGAC
                     SRTCGGGIRTAIRECNRPEPKNGGRYCVGRRMKFKSCNTEPCPKHKRDFREEQCAYFD
                     GKHFNINGLLPSVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTN
                     DICVQGLCRQAGCDHILNSKARKDKCGICGGDNSSCKTVAGTFNTVHYGYNTVVRIPA
                     GATSLDVRQHSFSGKSEDDNYLALSNSRGEFLLNGDFVVSMSKREVRVGSAMIEYSGS
                     DNVVERLNCSDRIEEELLLQVLSVGKLYNPDVRYSFNIPIEDRSQQFYWNSHGPWQAC
                     SKPCQGERRRKLVCTRESDQLTVSDQRCDRLPQPGPVTEACGTDCDLRWHIASKSECS
                     AQCGLGYRTLDIHCAKYSRVDGKTEKVDDSFCGSQPRPSNQEKCSGECSTGGWRYSAW
                     TECSKSCDGGTQRRRAICVNTRNDVLDDSKCAQQEKVIVQRCNEFSCPHWKTGEWSEC
                     LVTCGKGHKHRQVWCQFGEDRLSDRMCDPEAKPEPMQMCQQPECAAWQAGPWGQCSVT
                     CGQGYQLRAVKCIMGTYMSVVDDNDCNAATRPTDTQDCELSSCHPSILTLEPRRHVHG
                     VPRTQWRFGSWTPCSATCGKGTRMRYVSCRDEDGSVADESACATLPKPVAKEECSVTP
                     CGQWKALDWSSCSMTCGQGKATRQVVCVNYSDHVIDQSECDPDYIPETDQDCSMSPCP
                     QWTGSAYPFQNEDFRPRSDSPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDE
                     NGYTATDCVERIKPDEQRACESGPCPQWAYGSWGECTKLCGGGMRTRLVVCQRANGDR
                     FPDLSCEVLDKPPDREQCNTHACPQDAAWSTGPWSSCSVSCGRGHKHRNVYCLAKDGS
                     HLESDYCKHLPKPHGHRRCRGGRCPRWKAGAWSQCSVSCGQGVQQRHVGCQIGTHKTA
                     RESECSSYSRPESERVCQASPCPLYTWRAEQWQQCTKTCGEGSRYRQVVCVAEDQSEV
                     HSAHCDSDQRPPDRESCSLQPCEYVWITGEWSECSVTCGKGYRQRLVSCSEIYTGKEN
                     YEYSYQTTVNCPGTQPPSVHPCYLRDCPVSATWRVGNWGSCSVSCGMGVMHRSVQCLT
                     NEDQPSHLCPTDIKPEERKTCHNVYNCELPQNCKEVKKLNSASVDGEYFLAVRGKPLK
                     VFCAGMHSDYPKEYVTLAHGDSENFSEVYGHRLHNPTECPYNGSRRDDCHCRKDYTAA
                     GFSSFQKIRIDLTSMQIITTDLEFARTSEGHPVPFATAGDCYSAAKCPQGRFSINLYG
                     TGLSLTESARWTSQGNYAVSDIKKSPVRLCIAWGMVLV"
     exon            453..856
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            857..1019
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1309
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1393
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1509
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..1550
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            1551..1656
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1803
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..1945
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            1946..2091
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            2092..2273
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            2274..2410
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..2528
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            2529..2624
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            2625..2791
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            2792..2921
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            2922..3048
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            3049..3259
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            3260..3424
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            3425..3589
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            3590..3709
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            3710..3814
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            3815..3982
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            3983..4240
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            4241..4402
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            4403..4579
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            4580..4747
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            4748..4921
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            4922..5092
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            5093..5287
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            5288..5420
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            5421..5515
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            5516..5610
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            5611..5744
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            5745..5836
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            5837..6023
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            6024..6118
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
     exon            6119..7965
                     /gene="Adamts9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaagggcgcc cggcgcgcct cggagcgcac gttccgcgcc ttctcctgcc cgcaggctgg
       61 acattatgcg gcggagccgc cgagccctag tcctccgcct ccttctcctc ctcctgcggc
      121 ccgagcgcct cagctcacgg caggcggcag cgttgctcag cggagcgcag acgggaccct
      181 ctctgcagga cctcagcgac tcctaaagtc aaaaagttgg cggcagggcg ccggggttcc
      241 gcgcgctctc cacggccgct gcctcgcgtc gccgccagcc accaaagcgg gcaggaggga
      301 gggggtggga gaagcggggg gaggggtgag gagcaccatg cagttagtat cctgggccac
      361 actgctaacg ctcctggtgc cggacctggt tgagatgagg agccccgact ccgcggcggc
      421 cgtgcgcaag gacaggctgc acccgaggca agtgaaatta ttagagagtc tgagcgaata
      481 tgagatcgcg tctcccatcc gagtgaaccc cctcggggaa ccctttccca cgaacgtgca
      541 cttcaaaaga aggcgacgaa gcattaactc tgcctctgac ccctggcctg ccttcgcctc
      601 ctcctcctcg tcttcctcta cctcttccca ggagcattac cgcctcaaag ccttcggcca
      661 gcagtttcta tttaatctca ccgcccatac cggatttatc gctccactgt tcactgtcac
      721 cctccttgga gagccagggg tgaaccagtc caaactgtat tccgaggaag aaatggaact
      781 taggcactgt ttctacaaag gccatgtcaa taccaagtct gagcacactg cggtcatcag
      841 cctgtgctcc ggaatgatgg gcacgttccg gtctcacgat ggagattatt ttattgaacc
      901 actgctgtcc gtggatgagc aagaggatga ggaggaacag aacaaacccc acgtcattta
      961 taggcgcaac aaccctcaga gggaaccctc cacaggaaag catgcctgtg acacctcaga
     1021 actcaaaaat agctacagta aagacaagag gaaaaccaga cttcgaaaac ggagaaagag
     1081 gaatagcctg gctgacgacg tggcagcgtt aaagagaggc atggcaacta aggcgttctc
     1141 tggttataac aacaggacaa atggcacgag ggacagaagg aaccacaaaa gaaccaaacg
     1201 ctttctgtcc tatccacggt ttgtagaagt gatggtagtg gctgaccaca ggatggtttt
     1261 ataccatgga tcaaaccttc agcattatat tttaacctta atgtcaattg tagcttctat
     1321 ctataaagac tcaagtattg gaaatttaat taatattgtt attgtgaact tagttgtgat
     1381 tcataatgaa caggaaggac cttccataaa tttcaatgcc cagacaacat taaagaactt
     1441 ttgccagtgg cagcattcca agaaccactt gggtgggatt cagcatgaca cagctgttct
     1501 agtcacaagg gaggatatct gcagagctca ggacaaatgc gacaccttag gtcttgccga
     1561 attgggaacc atctgcgacc cctacagaag ctgttccatt agtgaagaca gtggcttgag
     1621 cacagcgttc accatagccc acgagctggg ccatgtgttt aatatgcctc atgatgacag
     1681 caataaatgc aaagaagaag gcgttaagag cccccagcat gtcatggcgc caacactgaa
     1741 cttctacacc aacccctgga tgtggtccaa gtgcagtcgg aagtacatca ccgagttctt
     1801 agacactggg tatggagagt gcttgttaaa tgaacctcaa tccaggacct atcctttgcc
     1861 ttcccaactg cccggccttc tctacaacgt gaataaacaa tgtgaactga tttttggacc
     1921 aggctctcaa gtgtgcccat atatgcactg caagtttgga ttctgtgttc ccaaagaaat
     1981 ggagggccct gcaattgatg gatcctgggg aagttggagt cactttgggg cctgctcaag
     2041 aacatgtgga ggaggcatca gaacagccat cagagagtgc aacagaccag agccaaaaaa
     2101 tggtgggagg tactgtgtag ggaggagaat gaagttcaaa tcctgcaaca ccgagccctg
     2161 cccgaagcac aagcgagact tccgtgagga gcagtgtgct tactttgacg gcaagcactt
     2221 caacatcaat ggtctgctgc ccagtgtacg ctgggtccct aagtacagtg gaattttgat
     2281 gaaggaccga tgcaagttgt tctgcagagt ggcaggaaac acagcctact accagcttcg
     2341 agacagagtg attgacggaa ccccctgtgg ccaggacaca aatgacatct gtgtccaagg
     2401 cctttgccgg caagctggat gtgatcatat tttaaactca aaggcccgga aagataaatg
     2461 tgggatttgt ggtggcgata attcttcatg caaaacagtg gcgggaacat ttaacacggt
     2521 ccattatggt tacaatactg ttgtccgaat tccagccggt gctaccagcc ttgatgtgcg
     2581 acagcacagc ttctcaggga agtccgagga tgacaactac ctagctttat caaacagtag
     2641 aggtgaattc ctgctcaatg gagactttgt tgtctccatg tccaaaaggg aggtccgcgt
     2701 ggggagtgcc atgattgagt acagtggatc cgacaatgtg gtggaaagac tgaactgttc
     2761 agaccgtatc gaggaagaac ttctcctaca ggtattgtca gtggggaagt tgtacaaccc
     2821 agatgtgcgg tattcattca atattccaat tgaggacaga tctcaacagt tttactggaa
     2881 cagtcatggg ccgtggcaag catgcagcaa accctgccaa ggggagcgga gacgaaaact
     2941 tgtttgcacc agggagtctg atcaacttac cgtttctgat caaagatgtg accggctgcc
     3001 ccagccagga cctgtcactg aagcgtgtgg tacagactgt gatttgaggt ggcacatcgc
     3061 cagcaagagc gaatgcagtg cccagtgtgg tctgggttat cgtactttag atatccactg
     3121 tgccaaatac agcagggtgg atgggaagac ggagaaggta gatgacagtt tttgtggcag
     3181 tcaacccaga ccaagcaacc aggagaaatg ctcaggagag tgcagcacag gcggatggcg
     3241 ctattctgcc tggacagaat gttctaaaag ctgtgatggt ggtacccaga gaagaagagc
     3301 aatttgcgtc aacacccgca atgatgtcct ggatgacagc aaatgcgcac agcaggagaa
     3361 agtcatcgta cagagatgca atgagttctc ctgtcctcat tggaaaacag gagagtggtc
     3421 agagtgcttg gtcacctgtg gaaaaggaca taagcaccgc caggtctggt gtcagtttgg
     3481 tgaagatcga ttaagcgata gaatgtgtga ccccgaggcc aagccggagc ccatgcagat
     3541 gtgtcagcag ccagagtgcg cagcctggca ggcgggtccc tggggacagt gcagtgtcac
     3601 ttgtggacag ggataccagc taagagcagt gaagtgcatc atggggactt acatgtcagt
     3661 ggtcgatgac aatgactgta atgcagccac taggccaacc gatacccagg actgtgaact
     3721 atcgtcctgt cacccttcca tactcaccct ggaaccaagg agacatgtac acggtgtacc
     3781 cagaacccag tggcgatttg ggtcttggac tccatgctca gccacttgtg gaaaaggtac
     3841 ccggatgaga tatgttagct gccgggacga ggacggttct gtggctgatg agagtgcctg
     3901 tgctaccttg cctaaaccag tagccaaaga agagtgttcc gtgacaccct gtggacagtg
     3961 gaaggctcta gactggagct cttgttccat gacttgtggg caaggtaagg cgacccgaca
     4021 agtggtgtgt gtcaactaca gtgaccacgt gatcgatcag agtgagtgtg acccagatta
     4081 tatcccagag actgaccagg actgctctat gtcaccatgc cctcaatgga ctggctcggc
     4141 ttacccattt caaaacgagg atttccgtcc caggagtgac agccctagcc gtacacacgt
     4201 gcttggagga aaccagtgga gaactggccc ctggggagcc tgttctagta cctgtgccgg
     4261 aggctcccag aggcgagttg tggtgtgtca ggacgaaaac ggatacacag ccaccgactg
     4321 cgtagagaga atcaagcctg atgagcaaag agcctgtgaa tctggcccgt gtccccagtg
     4381 ggcttacggc agctggggag agtgtaccaa gctgtgtggt ggaggcatgc ggacaagact
     4441 ggtggtctgt cagcgggcca atggtgaccg cttcccagat ttgagttgtg aagtcctcga
     4501 caaacctcct gaccgtgaac agtgcaacac acacgcttgc ccacaagatg ctgcgtggag
     4561 tactggcccg tggagctcgt gttctgtctc ttgtggtcga gggcataaac atcgaaatgt
     4621 ttactgcttg gcaaaagatg gaagccattt agagagtgat tactgtaagc accttcctaa
     4681 gccacatggg cacagaaggt gccgaggagg acggtgtccc cgatggaagg ctggcgcatg
     4741 gagtcagtgc tctgtgtcct gtggccaagg agtgcagcag aggcatgtgg gctgtcagat
     4801 cgggacacac aaaacagcca gagagagtga gtgcagttca tacagcagac cagagtcgga
     4861 gcgtgtctgc caagcctcac catgtcctct ctacacttgg agggcagagc aatggcaaca
     4921 atgcaccaag acgtgtggag aaggttcccg gtaccggcag gtggtatgtg tggcagagga
     4981 ccaaagtgaa gtgcacagtg cacattgtga ctcagaccaa cggcctccag accgtgagag
     5041 ctgcagccta cagccctgcg agtacgtgtg gatcacagga gaatggtctg agtgctcagt
     5101 gacctgtgga aagggctaca ggcaaaggct ggtctcctgc agtgagattt atacgggcaa
     5161 ggagaattac gaatacagct accaaaccac agtgaactgc ccaggcacac agcctcccag
     5221 cgtccatccc tgctacctga gggactgtcc tgtctcggcc acctggagag ttggtaactg
     5281 gggcagttgc tcagtgtcct gcggcatggg agtgatgcat agatctgtgc agtgtttaac
     5341 taacgaagat caacccagcc acttatgtcc cactgatata aagccagaag aaagaaaaac
     5401 ctgtcacaat gtttataact gtgagttacc ccagaactgc aaggaggtaa aaaaactcaa
     5461 tagcgccagc gttgatgggg aatatttcct ggctgtcagg ggaaagccac taaaggtatt
     5521 ctgtgcaggg atgcattctg actatcccaa ggagtacgtg acgctggccc atggtgactc
     5581 ggagaacttc tccgaagttt acgggcacag gttgcacaac ccaacagaat gtccctataa
     5641 cgggagccga cgggatgact gccattgccg gaaggattac acagctgctg gcttctccag
     5701 tttccagaaa atccgaattg acctgaccag catgcagatc ataaccactg acttagagtt
     5761 tgcaaggaca agtgaagggc atcctgttcc ttttgccacc gctggggact gctacagtgc
     5821 tgccaaatgc ccacagggcc gttttagcat caacctttat gggaccgggc tgtccttaac
     5881 cgagtctgcc agatggacat cacaagggaa ttatgccgtt tcagacatca agaagtctcc
     5941 ggtaaggctc tgtattgctt gggggatggt tcttgtttaa catcttatga agacggtggc
     6001 tctgtactga aggagcagag ccggacggta cccgggtcat agggaaatgc ggcggttact
     6061 gtgggaagtg tacaccatcc tccggcactg gcctggaggt gcgagtttca taactaaggg
     6121 gctctgaaga ggaagccata tgagacggat gaaggatgaa ttcaatacct ccaccttaaa
     6181 tttgggtgca tctgtgtgag tgtgtgtgga tctagctgcg tgtgtgtgtg aatgtgtgtg
     6241 tatgtgtgtg tacatatgca tatatataaa tatatattat atatatatat atacaggttg
     6301 agcatccctc atctaaaaat ttaagctctg aaatgctcca aattccgaaa cccattgagg
     6361 gccagcgtga gatctcagac ttcatgccat gaaacttggt ttcatacaca gaattatatt
     6421 tctgtcacgc atgtaaaggc gtatagggaa cacaaacaag acgcagaacc cacattctta
     6481 ggcatgtatt gctctcttcc tgggtacctt atttcttaaa acctttgcta aaatctccaa
     6541 gtagactaca gctcatttaa aagaaagaag cataaattaa taccatgttt agacgagccc
     6601 cacctccaag agatctcatt ttaaatagga aaaacatcgc caagtcttca aaacttctga
     6661 aacacacact gatggtctca agcatttcaa cgagggatac tcaacctgcg gaatccccta
     6721 atgatgtaaa gtttaatatt tatgtttgaa attatttatt gcgatgtaat atttttgtac
     6781 gtaaaatgat tttattgtga ctgcccacgc atgatgctcc cccttgcagt cagaccgctg
     6841 cattttacgt actctacgtt atatgtagta tatgacaaag tgactcttcg ttatcacggt
     6901 acactgttgt ttacctttta cctggaaatg tgttttactg ttacattttg aaaattgtaa
     6961 ttattttttt aacaacctag ctgacatcaa ggtgctacgt gagttgaata agggtatttt
     7021 tggcaattgt gggaacgttt cattagccaa tgtgtaagtt aagcaacatc acaggttcta
     7081 ccacttttaa tcatagcctc tgttccgttt catgtgatct ctgggaagaa ctatgctgcc
     7141 ttggtgctaa tatattatgt ttttaaagta attgtcaaga ggaaaaactg taaacactta
     7201 acaaaaggga gcaagagcta gacaattccc aatggataaa atcgtttgcc acagtaagac
     7261 cccctattta cgcttctttt tagacctgtc tcttttttta taatagctgg actcttttct
     7321 tacttaccgt tgttgttggg aatatgttct actctggtcc atggtgcctt ggactccttt
     7381 caatcactgg aagggtccac caatagcttc attacagagt aacactggga aaggaggctt
     7441 tcctgctgat ttgtcacgat atcctccaag tttatgagca gcaagacaaa ggatatacca
     7501 gaggagtatg gccgggcctt aacacgcctc tgcatactca tggccttcag caccctccgg
     7561 catacttgga gaatgacagg agatcgacca ccttttacct gaaaactttg gccaatgata
     7621 tgacgtccct tgaggctggt agcctaatac cctgccgggt ttcctgtggt cttcagcgtt
     7681 tgtgtgaaaa acaaactggt gtataggatg cccaggtctt tctgatcttc caggaatcca
     7741 ccttttgtta ctcctttcag gaatgaacat gctggaggca gtggtcacag acgttttact
     7801 tgagaaagtc tgcccaagct ttccaagacc aaagaaatta ggaaaaccct gacagtattc
     7861 tccaactcca cagaaatgcc agagcacttg gtgtatgaac aagtgtcatt tttctattgt
     7921 taatacatgt gaaacatatt atgaataaat attgtgacca catcc
//
