LOCUS       XM_003750455            3387 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ADAM metallopeptidase with
            thrombospondin type 1 motif, 8 (Adamts8), mRNA.
ACCESSION   XM_003750455
VERSION     XM_003750455.5
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051343.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 11, 2024 this sequence was replaced by
            NM_001427178.1.
            
            On Jan 21, 2021 this sequence version replaced XM_003750455.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3387
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3387
                     /gene="Adamts8"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif, 8; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 9 ESTs, 5 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 46 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:300475"
                     /db_xref="RGD:1308511"
     CDS             37..2754
                     /gene="Adamts8"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 8"
                     /protein_id="XP_003750503.1"
                     /db_xref="GeneID:300475"
                     /db_xref="RGD:1308511"
                     /translation="MLRDPTATRWPPLLLLLLQLPPPPLVCGAPARPGTRTQASELVV
                     PTRLPSSASELAFHLSAFGQSFVLRLAPDASFLAPEFKIERLGGSSAAAGGEPGLRGC
                     FFSGTVNGERESLAAMSLCGGLSGSFLLAGEEFTIQPQGAGDSLDQPHRLQRWGPGQR
                     REDPGLAAAEVFPLPQGLEWEVEMGDGQGQRRRDNEEDRERDKEGLRKETEDSREVTP
                     PFGSKTRSKRFVSEARFVEILLVADASMAAFYGTDLQNHILTVMSMAARIYKHPSIRN
                     SINLVVVKVLIVEEEGWGPEVSDNGGLTLRNFCSWQRRFNKPSDRHPEHYDTAILFTR
                     QNFCRKGEQCDTLGMADVGTICDPNKSCSVIKDEGLQAAYTLAHELGHVLSMPHDDSK
                     PCVRLFGPMGKYHMMAPFFIHVNKTLPWSPCSAVYLTELLDDGHGDCLLDAPTSVLPL
                     PTGLPGHSTLYELDQQCKQIFGPDFRHCPNTSVEDICVQLWCRHRDSDEPICHTKNGS
                     LLWADGTPCGPGHLCLDGSCVLREEVENPKAVVDGDWGPWGPWGQCSRTCGGGIQFSN
                     RECDNPAPQNGGRFCLGERVKYQSCKTEECPPNGKSFREQQCEKYNAYNHTDLDGNFL
                     QWVPKYSGVSPRDRCKLFCRARGRSEFKVFETKVIDGTLCGPDTLAICVRGQCVKAGC
                     DHVVNSPKKLDKCGVCGGKGTACRKVSGSFTPFSYGYNDIVTIPAGATNIDVKQRSHP
                     GVQNDGSYLALKTANGQYLLNGNLAISAIEQDILMKGTILKYSGSMATLERLQSFQAL
                     PEPLTVQLLTVSGEVFPPKVKYTFFVPNDTDFNVQSSKERASTNIIQSLPYAEWVLGD
                     WSECPSTCGGGWQRRTVECRDPSGQASDTCDEALKPEDAKPCGSQPCLL"
ORIGIN      
        1 ttttccctct cccccgctcc gcagccctct gcccccatgc tccgcgaccc caccgccacc
       61 cggtggcctc ccctcctgct gctgctattg cagctgccgc cgccaccact cgtctgcggc
      121 gccccggcga ggccgggaac ccggacgcag gcctcggagc tagtggtgcc cacgcggttg
      181 cccagcagcg cgagcgagct cgccttccac ctgtccgcct tcggccagag cttcgtgctg
      241 cgcctggcgc cggacgccag cttcctggcg ccggagttca agatcgagcg actcgggggc
      301 tcgagcgcgg cggccggggg cgagccgggg ctgcgcggct gcttcttctc tggcacagtg
      361 aatggagagc gggagtcgct ggcggcgatg agcctgtgtg gtgggctgag cggctcattc
      421 ttgctggctg gagaggagtt caccatccag ccacagggcg ctggggactc cctggaccag
      481 ccgcatcgcc tgcagcgctg ggggccggga cagcgccgcg aggaccccgg gctcgctgcc
      541 gcggaggtct tccccctccc tcaaggacta gaatgggagg tggagatggg tgatgggcag
      601 ggacagagaa gacgtgacaa cgaagaggac agggagcggg acaaagaggg gttgcgcaaa
      661 gagacagaag actcccgcga agtgacacca cccttcggat ccaaaactag gagcaagaga
      721 tttgtatccg aggctcgctt cgtggaaata cttctggtgg ctgatgcgtc catggctgcc
      781 ttctatggga cggacctgca gaaccacatc ctcacagtga tgtcaatggc agcccgaatc
      841 tacaagcacc cgagcatcag gaactccatc aaccttgtgg tggtgaaagt gctaatagtg
      901 gaagaggaag gatggggccc ggaggtgtcg gacaacgggg ggctcacact gcgcaacttc
      961 tgctcctggc agcggcgctt caacaagccc agcgaccgcc accccgagca ctatgacacg
     1021 gccatcttgt tcaccagaca gaacttctgc aggaagggag agcagtgtga caccctgggg
     1081 atggcagatg ttggcaccat ctgtgacccc aacaagagct gctcagtgat caaggatgag
     1141 ggactgcagg cagcctacac cctggcccat gaactaggac acgtcctcag catgccccat
     1201 gatgattcta agccatgcgt gagactgttt gggcccatgg gcaagtacca catgatggcg
     1261 ccattcttca tccacgtgaa caagacgctg ccctggtctc cctgcagtgc tgtctacctc
     1321 acggagctcc tggatgatgg tcacggagac tgcctcctgg atgcccccac ctcagttctg
     1381 cccctcccca cgggcctccc aggccacagc accctctatg agctggacca gcagtgcaag
     1441 cagatctttg ggcctgattt ccgacactgc cccaacacct ctgtggagga catctgtgtc
     1501 cagctctggt gccgtcatcg ggatagtgat gagcccattt gccacacaaa gaatggcagc
     1561 ttgctctggg ctgatggtac gccctgtggc cctgggcacc tgtgcctgga tggtagctgt
     1621 gtgctccggg aggaagtaga gaatcccaag gctgtggtag atggagactg gggtccctgg
     1681 ggaccctggg gacaatgttc tcgcacctgt ggtggaggga tacagttttc gaaccgtgag
     1741 tgtgataatc cagcacctca gaatggagga agattttgcc tgggagagag agtcaagtac
     1801 caatcttgca agacagagga atgtccacca aatggaaaaa gcttcaggga gcagcagtgt
     1861 gaaaaatata atgcctacaa ccacacggac ctggatggga atttccttca gtgggtcccc
     1921 aaatactcag gagtgtcccc ccgagaccga tgcaaactgt tttgcagagc ccgtgggagg
     1981 agtgagttca aagtgtttga aactaaggtg atcgatggca ctctgtgcgg accggatact
     2041 ctggccatct gtgtgcgggg acagtgcgtt aaggctggct gtgaccatgt ggtgaactca
     2101 cctaagaagc tggacaagtg tggggtgtgt gggggcaaag gcactgcctg taggaaggtc
     2161 tcaggttctt tcaccccctt cagttatggc tacaatgaca ttgtcaccat cccagctggt
     2221 gccacaaata ttgatgtgaa acaacggagc cacccagggg tccagaatga cggcagctac
     2281 ctggcactga agacagccaa tgggcagtac ctgctcaatg gtaacctagc catctctgcc
     2341 atagagcaag acatcttgat gaaggggacc atcctaaagt acagtggttc catggccacc
     2401 ctggagcggc tgcagagctt ccaagccctc cctgagcctc ttacagtaca gctcctgact
     2461 gtgtctggtg aggtcttccc tccaaaagtc aaatatacct tcttcgtccc caatgacacg
     2521 gacttcaacg tgcagagtag caaagaaaga gcaagcacca acatcattca gtccttgccc
     2581 tatgcagagt gggtgctggg ggactggtct gaatgtccaa gcacatgtgg aggtggctgg
     2641 cagcggcgga ctgtggaatg cagggacccc tcaggtcagg cctctgacac ctgtgatgag
     2701 gctctgaaac ctgaggatgc caagccctgt ggaagccagc catgtctcct ctgatcccct
     2761 tggtggacat gtctaaggct tatggatttg ggctactggc gtacagacaa aggtctcctc
     2821 tgaggtgaca ctacatatca agatggcatg gcccttccag gccttctatt actacaaccc
     2881 tttgggtacc acctaattca taaggaagag agaagaggat gtaagggtaa cagactgtaa
     2941 agttgactgt ctagtggact ggaccttgtt tatgaccaag aagatggtat aggttaaaag
     3001 gtaaaagtgt gcttattgat ccaaaggtga gatttcagaa ccagcctctt tgcaaaggac
     3061 tagaaaggtt aaatgagaaa gaagaatttt ttttctcttt ggtttctcca ataatcaatc
     3121 tacctcacag cgggaggaac ttggtgtata aggccaggtg ttagtggtga gtgccaaggc
     3181 actctccata gatatcttcg agccatcttc agaaatggcc atggctgttt tcagtattaa
     3241 aactctgttg tctcaaaagg tggtggtgtc catcacaggg ttatagaaag ccacttgttc
     3301 tcaggctgcc tcctgctggg gcggacccct ttcaagtatt tatgcaaata tgtctctgaa
     3361 ctaaagtgtg atcttacacc aatgaaa
//
