LOCUS       NM_001421315            7806 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ADAM metallopeptidase with thrombospondin type 1
            motif, 20 (Adamts20), mRNA.
ACCESSION   NM_001421315 XM_039080334
VERSION     NM_001421315.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7806)
  AUTHORS   Silver,D.L., Hou,L., Somerville,R., Young,M.E., Apte,S.S. and
            Pavan,W.J.
  TITLE     The secreted metalloprotease ADAMTS20 is required for melanoblast
            survival
  JOURNAL   PLoS Genet 4 (2), e1000003 (2008)
   PUBMED   18454205
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7806)
  AUTHORS   Llamazares,M., Cal,S., Quesada,V. and Lopez-Otin,C.
  TITLE     Identification and characterization of ADAMTS-20 defines a novel
            subfamily of metalloproteinases-disintegrins with multiple
            thrombospondin-1 repeats and a unique GON domain
  JOURNAL   J Biol Chem 278 (15), 13382-13389 (2003)
   PUBMED   12562771
  REMARK    Erratum:[J Biol Chem. 2018 Jul 27;293(30):11785. PMID: 30054291]
REFERENCE   3  (bases 1 to 7806)
  AUTHORS   MAYER,T.C. and MALTBY,E.L.
  TITLE     AN EXPERIMENTAL INVESTIGATION OF PATTERN DEVELOPMENT IN LETHAL
            SPOTTING AND BELTED MOUSE EMBRYOS
  JOURNAL   Dev Biol 9, 269-286 (1964)
   PUBMED   14138974
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000007.1.
            
            On May 16, 2023 this sequence version replaced XM_039080334.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-304               JAXUCZ010000007.1  127406993-127407296 c
            305-666             JAXUCZ010000007.1  127406181-127406542 c
            667-835             JAXUCZ010000007.1  127392212-127392380 c
            836-1074            JAXUCZ010000007.1  127376452-127376690 c
            1075-1158           JAXUCZ010000007.1  127365958-127366041 c
            1159-1283           JAXUCZ010000007.1  127365228-127365352 c
            1284-1324           JAXUCZ010000007.1  127364038-127364078 c
            1325-1430           JAXUCZ010000007.1  127359330-127359435 c
            1431-1577           JAXUCZ010000007.1  127357539-127357685 c
            1578-1719           JAXUCZ010000007.1  127355510-127355651 c
            1720-1824           JAXUCZ010000007.1  127352996-127353100 c
            1825-1970           JAXUCZ010000007.1  127351387-127351532 c
            1971-2152           JAXUCZ010000007.1  127349587-127349768 c
            2153-2289           JAXUCZ010000007.1  127349353-127349489 c
            2290-2407           JAXUCZ010000007.1  127346754-127346871 c
            2408-2503           JAXUCZ010000007.1  127343844-127343939 c
            2504-2670           JAXUCZ010000007.1  127340755-127340921 c
            2671-2800           JAXUCZ010000007.1  127340493-127340622 c
            2801-2927           JAXUCZ010000007.1  127334957-127335083 c
            2928-3138           JAXUCZ010000007.1  127332179-127332389 c
            3139-3303           JAXUCZ010000007.1  127331865-127332029 c
            3304-3468           JAXUCZ010000007.1  127331287-127331451 c
            3469-3588           JAXUCZ010000007.1  127330219-127330338 c
            3589-3696           JAXUCZ010000007.1  127327329-127327436 c
            3697-3861           JAXUCZ010000007.1  127326451-127326615 c
            3862-4152           JAXUCZ010000007.1  127326060-127326350 c
            4153-4314           JAXUCZ010000007.1  127325028-127325189 c
            4315-4488           JAXUCZ010000007.1  127323169-127323342 c
            4489-4656           JAXUCZ010000007.1  127299080-127299247 c
            4657-4830           JAXUCZ010000007.1  127293873-127294046 c
            4831-5001           JAXUCZ010000007.1  127293195-127293365 c
            5002-5205           JAXUCZ010000007.1  127291420-127291623 c
            5206-5335           JAXUCZ010000007.1  127290539-127290668 c
            5336-5430           JAXUCZ010000007.1  127290243-127290337 c
            5431-5522           JAXUCZ010000007.1  127290067-127290158 c
            5523-5656           JAXUCZ010000007.1  127289363-127289496 c
            5657-5748           JAXUCZ010000007.1  127287118-127287209 c
            5749-5853           JAXUCZ010000007.1  127280787-127280891 c
            5854-7806           JAXUCZ010000007.1  127275538-127277490 c
FEATURES             Location/Qualifiers
     source          1..7806
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q35"
     gene            1..7806
                     /gene="Adamts20"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif, 20"
                     /db_xref="GeneID:315263"
                     /db_xref="RGD:1307725"
     exon            1..304
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     CDS             214..5943
                     /gene="Adamts20"
                     /note="A disintegrin and metalloproteinase with
                     thrombospondin motifs 20; a disintegrin-like and
                     metallopeptidase (reprolysin type) with thrombospondin
                     type 1 motif, 20"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 20 precursor"
                     /protein_id="NP_001408244.1"
                     /db_xref="GeneID:315263"
                     /db_xref="RGD:1307725"
                     /translation="MRVAKWLTGLLCPISLLLTGSWEVRFHPRQEALVKTLASYEVVT
                     PTRVNEFGDVFPQNRHFSRKKRSSGVPEPPPLRTHYRISAYGQLFQLNLSADSAFLAA
                     GYTEVHLGTPVPGPGGRSAEPPDLRHCFYRGQVNAREDHIAVFSLCGGLMGTFKANDG
                     EYFLEPVLKADGSEHEDDHNKPHLIYRQEVKRNAFVRSQSHGPCGVSENQTEKTALPS
                     PSFRNTTGDLNRRKGAVFGLEGERSRLHSRSKRFLSYPRYVEVMVTADAKMVRHHGQN
                     LQHYVLTLMSIVAAIYKDSSIGNLINIVIVKLVIIHSEQEGPVISFNAATTLRNFCLW
                     QQSQNVLDDAHPSHHDTAVLITREDICGAKEKCDTLGLAELGTLCDPSRSCSISEENG
                     LSAAFTIAHELGHVFNVPHDDSFKCKESGTKHQYHVMAPTLNYHTSPWTWSACSQKHI
                     TEFLDTGHGECLLDKPNGRTYDLSPQLPGSVYDGNKQCELMFGPGSQVCPYLKQCRRL
                     WCTSAEGVHKGCRTQHMPLADGTSCGPGMHCHRGLCVTRDMETRPVDGEWGPWGPYSS
                     CSRTCGGGIRSTARLCDRPEPRNGGRYCVGRRMKFRSCNTDSCPKGKRDFREKQCSDF
                     DGKHFDISGLPPNVRWLPKYSGIAVKDRCKLYCRVAGTTSFYQLKDRVADGTPCGTET
                     NDICVQGLCRQAGCDHVLNSKAKRDKCGVCGGDNSSCQTLAGVFNSAHYGYNVVVKIP
                     AGATNIEILQHSYSGRPEDDNYLALSDTQGNFLLNGNFVVSMAKKEINIQGAVFEYSG
                     SNNSIERINSTDRLEAELVLQVLCVGNLYNPDVHYIFNIPIEERSNLFSWDPYGPWQD
                     CTKMCQGLHRRKIACIRKSDRAVVSDQSCSHLPLPLFVTERCNTDCELRWHITGKSDC
                     SSQCGQGYRTLDVHCMKYSVHKGQTVPVGDQYCGDQLKPPNREPCHGSCVLTRWHYSE
                     WSQCSRSCGGGEKTRESYCVNGFGHRLAERECQELPRVVLGNCNDFPCPGWATSEWSE
                     CPVTCGKGMKQRQVWCQRSEDPVGDDFCDASTKPESLGPCELRACASWHVGPWGSCTV
                     TCGHGYQVRAVKCVSEILGTVLDDRECPRASRPSDRQDCIFAPCLAILKVGATSLPAI
                     PLGKAAQWRHGSWTPCSVSCGRGSQARYVSCRDAHDGVADELNCAHLPRPAEVSLCFS
                     PCGEWQAGDWSPCSASCGHGKTTRRVLCVNYHQLVDESYCDPEGRPVTEQECRLAACP
                     PSYSRSPSSSEQPSHGPGRNVPLTHKPEENPDQGVQLSIRGNQWRTGPWGACSRSCAG
                     GLQHRAVVCQDEDGRSATSCEATSKPPESKHCGSGPCPQWNYGDWGECTQTCGAGVKS
                     RFVICQFPDGQMAQEHSCELPKPPSMMQCHLRACPDDVSWYRGSWKSCSASCGKGIKY
                     REVLCIDQVQRKLEEKYCSHLHKPRTHKPCRSGRCPSWKANKWKECSVTCGSGVQQRE
                     VYCRLRGTGRVAEDMCEPSTRPQVQRPCWHQDCTRYQWTTGDWLDCSTSCKKKETYRL
                     VKCVNERNMQVNESLCDPLTKPVSIKKCRNSHCKYMVVTGDSSQCAGNCGLTYSQRIT
                     YCTRIQPPKKNAFHHQLRPVNYGQCPVIPSPQVYKCDIRSCLRGATWKVGKWSKCSVT
                     CGNGIMERRVACRTENGWPSDLCLKRLKPDAQKKCYANDCKLLTTCKEIQVTNNITKD
                     GNYDLNVRGRILKIHCSGMQLENPREYLPLVKVEDNFSEIYGLRLQNPYECPFNGSRR
                     ADCACENDYPPAGYTVFSKVRVDLASMQIKTTDLLFSRTLFGKAVPFATAGDCYSAAR
                     CPQGQFSINLAGTGMKVSSTAKWLAQGRYASVIIHRSQDGTKVYGRCGGFCGKCVPHV
                     STGLPIQVL"
     exon            305..666
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            667..835
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            836..1074
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            1075..1158
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1283
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1324
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1430
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1577
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..1719
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            1720..1824
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            1825..1970
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            1971..2152
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            2153..2289
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..2407
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            2408..2503
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            2504..2670
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            2671..2800
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            2801..2927
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            2928..3138
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            3139..3303
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            3304..3468
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            3469..3588
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            3589..3696
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            3697..3861
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            3862..4152
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            4153..4314
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            4315..4488
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            4489..4656
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            4657..4830
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            4831..5001
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            5002..5205
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            5206..5335
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            5336..5430
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            5431..5522
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            5523..5656
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            5657..5748
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            5749..5853
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
     exon            5854..7806
                     /gene="Adamts20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caagagccag gcgggctgcg cgcgatgagg cagcggtgcc gggagcggga gccggtggca
       61 gggcgaggcg ggcaggggtg cagtccaggg tgctccggag gctgctgaga cgccgcggag
      121 aaccgctaga gcgcagagga gggcagcgga gcgcggggaa ccagcggccc cggggcggcc
      181 tcccagtcgg gatcccctcc cctgtgtgca gccatgcggg tggccaagtg gctgaccggg
      241 ttgctctgcc cgatctcgct ccttctcact gggtcctggg aagttcgttt ccacccacga
      301 caggaagccc tggtgaagac tctggcctcc tacgaagtgg tgacccccac gcgggtcaat
      361 gagttcggag acgtgttccc ccaaaaccgg catttcagcc ggaagaaacg aagctccggg
      421 gtgccggagc ctcctccgct caggacccac taccgtatta gcgcctacgg gcagctcttc
      481 cagctgaacc tgagcgctga ctccgccttc ctggctgcag gctatactga ggtgcacttg
      541 gggaccccgg tgcccggacc aggcgggcgc agcgcggagc ccccagacct gcgccactgt
      601 ttctaccgtg gccaggtcaa cgcgcgagag gaccacattg ctgtcttcag tctgtgtggg
      661 ggactgatgg gaacattcaa agcaaatgat ggggagtatt tcttagagcc agtcctgaag
      721 gcagatggga gtgagcacga agatgaccac aacaagccgc atctgatcta cagacaggaa
      781 gtaaagagga acgccttcgt gcggtctcag tctcatgggc cttgcggagt ttcagaaaat
      841 cagacggaga aaactgcttt gccctctcct agcttccgga acacgaccgg agaccttaat
      901 aggaggaagg gagcggtgtt cggattggaa ggtgaacgga gccggttaca ttccaggagt
      961 aagcgtttcc tgtcgtaccc aagatacgtg gaagttatgg tgacggcgga cgctaagatg
     1021 gttcgccatc acgggcagaa tttgcagcac tatgtgctga cgctaatgtc catcgttgct
     1081 gcaatctaca aggattcgag cattgggaac cttataaata tagtgattgt gaagttagtg
     1141 ataattcaca gtgagcagga aggaccggtg atcagtttta atgcagccac cacgttgcgc
     1201 aacttttgct tgtggcaaca gagtcagaat gttctggacg atgctcatcc ttcccaccat
     1261 gacaccgcgg tcctcatcac tagggaagac atttgtggag ctaaggagaa atgtgacaca
     1321 ttaggcttag cggagttagg caccctgtgc gatccttcga ggagctgctc cattagcgag
     1381 gagaacggac tgagcgccgc cttcaccatc gcccacgagc ttgggcacgt gtttaacgtc
     1441 ccacacgatg acagttttaa atgtaaagaa tctgggacta aacatcagta tcacgtaatg
     1501 gccccgactc taaattacca cacaagccct tggacctggt cggcctgcag tcagaagcac
     1561 ataacggagt ttctggacac tggccatgga gaatgccttc tcgacaaacc caacggaaga
     1621 acctatgacc tgtctcccca gctcccaggc tcggtgtacg atgggaacaa gcagtgcgaa
     1681 ctcatgttcg gtcccggatc gcaagtgtgc ccctacttga agcagtgtcg gcgcctgtgg
     1741 tgcacgagcg cagaaggcgt ccacaagggc tgtcgcacac agcacatgcc gctggcagat
     1801 gggacaagct gtggtcctgg gatgcactgc caccgcgggc tgtgtgtgac cagagacatg
     1861 gagacccgtc ctgtggatgg cgagtggggg ccgtggggac cctacagctc gtgttccaga
     1921 acctgtggtg ggggaatcag gagcacagcc aggctctgtg accggcctga gccacgaaac
     1981 ggaggaaggt actgtgtggg ccgcaggatg aaatttcggt catgtaatac tgattcatgt
     2041 ccaaaaggca agcgagactt ccgagaaaag caatgttccg acttcgatgg taaacatttc
     2101 gacatcagcg gcctcccccc caatgtgagg tggcttccga agtacagcgg gatcgccgtc
     2161 aaagatcgct gtaaactcta ttgccgggtg gctgggacca ccagcttcta ccagctaaag
     2221 gacagagtcg ctgacgggac accctgtggg acggaaacta acgacatctg tgtccagggc
     2281 ctctgtcggc aagccggctg tgatcatgtg ttaaactcca aggccaagag agacaaatgt
     2341 ggagtgtgtg gtggtgataa ctcttcgtgc cagaccctgg cgggtgtctt caacagtgca
     2401 cattatggtt acaatgtcgt tgtaaagatc cctgcagggg ctacaaacat tgaaattctc
     2461 cagcacagct attctggaag accagaagat gacaactatc tcgcactgtc tgacactcaa
     2521 gggaacttcc ttctgaatgg aaactttgtt gtaagtatgg caaagaaaga gatcaacatc
     2581 cagggcgctg ttttcgagta cagtgggtcc aacaactcca ttgaaaggat caatagcacg
     2641 gaccggctgg aagcggagct tgttctgcag gtgttgtgtg tgggtaattt atacaaccct
     2701 gacgtgcact atatcttcaa catccccatt gaggagagga gtaatctgtt ctcctgggat
     2761 ccgtatgggc cgtggcaaga ctgtaccaaa atgtgccaag gtcttcatag aagaaaaatt
     2821 gcctgcattc gtaagagtga ccgtgcggtc gtatctgacc aaagttgtag ccacttaccg
     2881 ctgccactgt ttgtgactga aaggtgcaat acggactgtg aactcaggtg gcacatcacg
     2941 gggaaaagtg actgctcatc ccagtgtggc caaggataca ggaccctaga cgttcactgc
     3001 atgaagtact ccgttcataa aggacagact gtcccagtgg gagaccagta ctgtggtgac
     3061 cagctcaaac ctcccaaccg agagccctgt catggcagct gtgttttaac aaggtggcat
     3121 tattcagagt ggtcccagtg ttctaggagt tgtggcggcg gtgagaagac tcgagagtcc
     3181 tactgtgtaa acggctttgg ccaccgcctt gctgaacgag agtgtcagga gctccctcgg
     3241 gtggtgctgg ggaactgcaa tgactttccg tgtcccggct gggcaactag tgagtggagt
     3301 gagtgtcctg tcacgtgcgg aaagggaatg aagcagaggc aggtttggtg ccagcggagc
     3361 gaagaccccg tgggggatga cttctgcgat gccagtacca agcctgagtc gctgggaccc
     3421 tgtgagctcc gtgcgtgcgc ttcttggcat gtgggaccgt ggggttcttg cacggtcacc
     3481 tgtggacacg gataccaggt gcgtgctgtt aagtgcgtca gtgagatact tggcaccgtg
     3541 ctagatgaca gagaatgccc cagagccagc cggccaagtg acagacagga ttgtatattt
     3601 gcaccttgcc tggctattct aaaagttggg gccacctcct taccagccat tcccctggga
     3661 aaggcagcac agtggcgcca tggatcttgg accccatgct ccgtgtcctg tggaagaggc
     3721 agtcaggccc ggtacgtgag ctgccgtgac gcccacgatg gagtagcgga tgagttgaat
     3781 tgcgcccact tgcctcgacc tgctgaggtg tctctctgct tcagcccttg tggggagtgg
     3841 caagcagggg attggtcacc gtgttcagcc tcctgtggac atgggaaaac cactcggcgt
     3901 gttctatgtg tgaactacca ccaactggtg gacgagagtt actgtgaccc cgaaggccgt
     3961 cctgtgactg aacaagaatg tcgcctggcg gcctgcccgc cctcgtacag ccgctctccc
     4021 agctcctctg agcagccaag tcatggtcca ggcagaaatg ttccattaac tcacaaacca
     4081 gaagagaatc cagatcaggg ggtccagctg tcaatcagag gaaaccagtg gagaacaggc
     4141 ccttggggag catgctccag aagctgcgcg ggcggtcttc agcacagggc tgtggtctgc
     4201 caggacgaag atgggcgaag cgccacttcc tgtgaggcga cctccaagcc cccagagtca
     4261 aagcactgtg gctccggacc ttgtccgcag tggaattatg gggactgggg agaatgcaca
     4321 cagacctgtg gcgcaggggt aaaatcaaga tttgtgatct gtcagtttcc cgatggccaa
     4381 atggcacaag aacacagctg cgaactgccg aagccaccta gcatgatgca atgtcacctg
     4441 cgcgcctgcc ctgatgatgt gtcctggtat cggggatcat ggaaatcgtg ctcagcttct
     4501 tgtggtaaag gcataaagta ccgggaggtt ctctgcattg atcaagtcca aaggaaacta
     4561 gaagaaaaat attgcagtca tttgcataaa cctcggactc acaaaccttg cagatcagga
     4621 cgatgccctt cgtggaaagc caataaatgg aaggagtgct ctgtgacctg tgggtctggg
     4681 gtacagcaga gggaggtgta ctgcagactg agaggcactg gtcgagtggc tgaagacatg
     4741 tgtgagcctt ctacccggcc tcaggtgcaa cggccatgct ggcatcagga ctgtacgagg
     4801 taccagtgga caacaggaga ctggctagac tgttcaacat cctgtaagaa aaaggagacc
     4861 tatcggctgg tgaaatgcgt gaatgaacga aacatgcaag tgaatgaaag tctctgtgac
     4921 cctttaacga aacccgtttc gatcaaaaag tgcaggaatt ctcactgcaa gtacatggtg
     4981 gtgacaggag actcgtcgca gtgtgcaggt aactgtgggc tcacttactc acagaggatt
     5041 acatactgta ccaggatcca gccgcctaag aaaaatgcat tccatcatca acttcggcct
     5101 gtaaactacg ggcagtgccc cgtgatacct tctcctcagg tgtacaaatg cgacattaga
     5161 agttgtttgc gtggagccac ttggaaagtg ggaaagtgga gcaagtgctc agtaacttgt
     5221 ggaaatggga taatggagag aagagtagcg tgcaggactg agaacggttg gcccagtgac
     5281 ttatgtttaa agcgtttaaa gccagatgcc caaaagaaat gttatgccaa tgactgtaaa
     5341 ttactcacca cctgcaaaga aatccaagtt acaaacaaca ttaccaagga tggcaactat
     5401 gatcttaacg tcaggggaag aatattgaag attcattgct caggcatgca gctggagaac
     5461 cctagagaat atttacccct ggtcaaagtt gaagacaact tttcggaaat atatggcctt
     5521 agacttcaaa atccctacga atgccccttc aacggaagta ggagggcaga ctgtgcgtgt
     5581 gaaaatgact acccacctgc cggatacact gtttttagca aagtgagagt tgatctcgca
     5641 tccatgcaaa tcaaaacgac ggatcttctt ttctcccgga cactatttgg aaaggcagtt
     5701 ccatttgcca cagctggaga ctgctacagt gctgccagat gcccacaggg gcagttcagc
     5761 atcaacttag caggaactgg catgaaggta tctagcacgg caaagtggct cgctcagggg
     5821 aggtatgcct cggtcatcat ccacagatct caggacggaa ccaaagtgta cggcagatgc
     5881 ggagggttct gtggcaagtg cgttcctcac gtgtctacgg ggctcccgat tcaagtgcta
     5941 tgaccattca aggcttggaa gttccgcaaa agcggggtgg ctctgtggaa gcacaggtgt
     6001 ctggtgctcc tttctcactc ctggcttcct gagacttcca tatccaaacc tttctctggg
     6061 tgctcatcgg ggtttcagac cacttcatat ttatgggttt tcaagagtcg cttaacagac
     6121 accactctaa tcaggatcag ttttttgaac atcgtaattt attataggga atgcaggcat
     6181 aatgtttgaa tggattatac gaaggaaata ttactgttca cagcttagac tggaccataa
     6241 taatgttact ctcttaaaca cacacgggaa taaatctctg atccgcttcc tagggtacaa
     6301 ggaagggcta ttgtgattgt taaaatggag caagtaagaa ttagtgaata tcaaattaat
     6361 agttgtatca aataaacaca tagacaccat cctttctact gatatgattt tgattcattg
     6421 tcttattttt tctttaattt taatctatgg tttttttggt gcttcaataa aaatggttct
     6481 aaaatataac acattttttc ttaaaaatgt gtgctcatgt taagtattaa atagaaaact
     6541 ttgtggcaaa acggagaaga tatgatatat ttgagatttg agttttaagg cctacctctg
     6601 tatatgtatg agcaatatac tgtttttata atgtttatgt tctattatgt ctttataact
     6661 cacatatgta actacccgca aaaaaaagtc tattttctta gggttaaatg ccttttgggt
     6721 agccaaatag aaagatggac gttcttaaaa ttctgatgat cctaagtttt ggttctgttt
     6781 tcctgaaaat tctgttttcc tgtccctttt cccactttaa aagttcctta gagagtatgt
     6841 ggtggtgagg tttcctctag agcaaagatt ctcaacctgt gggtctcaac ctcttgggga
     6901 tctagtgact ctttcacggg agtcacctga gatcattggg aagcacagat atctacattg
     6961 ctcttcataa cagtagaaaa ctttagagtt atgaattagc aatgagataa ttttatggtt
     7021 gggggtcact gcagcatgtg ggactgtttt aaagagtcac ggcattagga taggaaggtt
     7081 gcgagtccgt tgttctagag gaacagataa cgttatcaaa gggatttatt agattggttt
     7141 gcactgttaa cagtctacgt actccaataa taattgtctt cacactgaga ctggacgccc
     7201 tagctgtctc agtccatact aatgaccttg acgtttgcca gagcagggat gtgggagcag
     7261 ggatgctctc cttcagccca tgtagaaagc tgcaaagctg aagtcagagg aaaatgatga
     7321 cggtctagtc agcgagtgca ccagcgaggc agtaagagaa gcaggcaaaa agcgaacgct
     7381 tgctttctct tccaaagtta gggcatggct ccctcacagt caacctaatg ggacatccgg
     7441 cacgggtgtg cgccagccgc ctgcttagtg ggcaagtcca gatcctgcca aacagatatt
     7501 ttcccacgtc ggcctaccct ataaaagcat gagatttact aactcagttt accagtaaat
     7561 ataagtgtac tagctttacc ctcaaggtgt ttttctccca aatatttgct agaggtgtaa
     7621 atggtaccag aggacgtcgg tgcgcatgcg gtcaaacact tgcagaattc tgaaaaaagg
     7681 ggagattctg cgaatcggtc aggcattaag acaggatgtc taatattttc cattcaatgt
     7741 tccatctgtt attaaggctg tgtaatttat aaacatctaa ataaaatatg tacttgtgtg
     7801 gcgcta
//
