LOCUS       NM_001108433            5131 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus ADAM metallopeptidase with thrombospondin type 1
            motif, 19 (Adamts19), mRNA.
ACCESSION   NM_001108433 XM_001060610 XM_006254755 XM_341619
VERSION     NM_001108433.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5131)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000301.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001108433.3.
            
            On or before Apr 8, 2021 this sequence version replaced
            XM_006254755.4, NM_001108433.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760396,
                              SAMN11044071 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-600               JACYVU010000301.1  14758840-14759439
            601-1253            JACYVU010000301.1  14759945-14760597
            1254-1419           JACYVU010000301.1  14801394-14801559
            1420-1592           JACYVU010000301.1  14810810-14810982
            1593-1676           JACYVU010000301.1  14812058-14812141
            1677-1834           JACYVU010000301.1  14812864-14813021
            1835-1878           JACYVU010000301.1  14829895-14829938
            1879-1984           JACYVU010000301.1  14843051-14843156
            1985-2125           JACYVU010000301.1  14852846-14852986
            2126-2276           JACYVU010000301.1  14855220-14855370
            2277-2378           JACYVU010000301.1  14864044-14864145
            2379-2509           JACYVU010000301.1  14869550-14869680
            2510-2682           JACYVU010000301.1  14870738-14870910
            2683-2810           JACYVU010000301.1  14875109-14875236
            2811-2931           JACYVU010000301.1  14887837-14887957
            2932-3012           JACYVU010000301.1  14891763-14891843
            3013-3170           JACYVU010000301.1  14900905-14901062
            3171-3324           JACYVU010000301.1  14904973-14905126
            3325-3460           JACYVU010000301.1  14915688-14915823
            3461-3665           JACYVU010000301.1  14921805-14922009
            3666-3818           JACYVU010000301.1  14922912-14923064
            3819-3996           JACYVU010000301.1  14937906-14938083
            3997-5131           JACYVU010000301.1  14941523-14942657
FEATURES             Location/Qualifiers
     source          1..5131
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..5131
                     /gene="Adamts19"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif, 19"
                     /db_xref="GeneID:361332"
                     /db_xref="RGD:1308359"
     exon            1..600
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     CDS             513..4148
                     /gene="Adamts19"
                     /note="A disintegrin and metalloproteinase with
                     thrombospondin motifs 19; a disintegrin-like and
                     metallopeptidase (reprolysin type) with thrombospondin
                     type 1 motif, 19"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 19 precursor"
                     /protein_id="NP_001101903.2"
                     /db_xref="GeneID:361332"
                     /db_xref="RGD:1308359"
                     /translation="MGPEMRLTRICCCCCLLYQLGFLSHGTISGMQLTPDLEEWEVVF
                     PALWRRESLNATGLSTGSADPGSGRSAGGGSRGQPSGSSREVRSVARAPLEEAAGGQS
                     EPWFAARPLQPGAEDEEELESQELPRGSSGDTSLPSGAPAPWQPSPSPQPPSSPPPAQ
                     QEEPSTEEVLLRIPALSRDLYLLLRRDGRFLAQRFAVEQWPKPGPDPTRATVDPRPPM
                     PSDASCFYTGTVLRHPGSLASFSTCGGGLMGFIQLNEDFIFIEPFNDTMAIIGHPHRL
                     YRQKRSSEERVTEKSAAHRHHCGVISDKGRPRSKKLAENRREKRYSYKLPQDYNIETV
                     VVADPAMVSYHGADAARRFILTILNMVFNLFQHKSLGVQVNLRVIKLILLHETPADLY
                     IGHHGEKMLESFCKWQHEEFGRKNDIHLEMSTSWGEDVASVDAAILITRKDFCVHKDE
                     PCDTVGIAYLNGMCSEKRKCIIAEDNGLNLAFTIAHEMGHNMGINHDNDHPSCADGLH
                     IMSGEWIKGQNLGDVSWSRCSKEDLERFLRSKASSCLLHTDPQSLSSVLVPSKLPGMA
                     YTADEQCQILFGPLASFCQEMQHVICTGLWCRVEGDTECRTKLDPPMDGTDCDPGKWC
                     KAGECTRRTPAPEHLAGEWSTWSSCSRSCGSGVSSRERKCPGLGSEARDCNGPRKQYR
                     ICENPPCPAGLPGFRDWQCQAYSVRTSYPKHALQWQAVFDEEKPCALFCSPVGKEQPV
                     LLSEKVLDGTSCGYQGLDVCANGRCQKAGCDGLLGSLAREDHCGVCNGNGKSCKVIKG
                     DFNHTRGAGYVEVLVIPAGARRIKVVEEKPAHSYLALRDASKQSINSDWKIEHSGAFS
                     LAGTTVHYIRRGLWEKISAKGPTTTPLHLLVLLFQDQNYGLHYEYTVPSDPLPDNQSS
                     KESGPLFMWTHAGWGDCNATCGGGERKTTVSCTKIMNKNISLVDNKKCKDLTKPEPQI
                     RKCNEQPCQTRWMMTEWTTCSRTCGKGVQSRQVACTRQLENGTLIRAWERDCIGPKPA
                     TMQRCEGQDCMTVWEAGVWSECSVKCGKGVRHRTVRCTNPRKKCVLSTRPREVEDCED
                     YSKCYVWRVGDWSKCSITCGKGMQSRVIQCMHKITGRHGNECFSSEKPAAYRPCHLQP
                     CNEKINVNTITSPRLAALTFKCLGDQWPVYCRVIREKNLCQDMRWYQRCCETCRDFYA
                     QKLRQKS"
     exon            601..1253
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..1419
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..1592
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            1593..1676
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1834
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            1835..1878
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..1984
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2125
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            2126..2276
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            2277..2378
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            2379..2509
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            2510..2682
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            2683..2810
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            2811..2931
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            2932..3012
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            3013..3170
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            3171..3324
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            3325..3460
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            3461..3665
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            3666..3818
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            3819..3996
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
     exon            3997..5131
                     /gene="Adamts19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcgtgtact cccccgcccc ctcccccggc caccctctcc gggccgcggc gcccgaggga
       61 gtgtgcagag agctctgccc accgcaagcc gtccaaactc gtgcgccggc cacactccgc
      121 gagggtgcgg cggcgaacct cggctgggac tggactgctc ctctggtccg gaggccgtcc
      181 tgccttctgc cccgcgcctc ctggctctcg gcggactgcg ggtctgtccc gccgggctcc
      241 agctgggcct ggaaactcca gcacggttca gagctcagaa agtcgactca tcacctaatt
      301 cgccggggag ctggagcgca gagagccggg gcgctgccgg ccgctcctcc ccaccccagc
      361 cccgcccggg ctctgggagt cacacagctt gccctcccgc ccccccaccc ctggcagaca
      421 aagggcctgg gcacagtcgc cgcctggccg ccggcgctcc ggggaggctg ctgcgtgcgc
      481 tgtggaacgc gcgggaggcg cgcgctgtgg agatgggccc ggagatgcgc ctgactcgca
      541 tctgctgctg ctgttgcctc ctctaccagc taggcttcct gtcgcatggg accatctcag
      601 ggatgcagct caccccggat ctcgaggaat gggaagtcgt gtttcctgca ctctggcgcc
      661 gggagtcgct gaacgccacg ggcctcagca cgggcagcgc agacccggga tccgggcgta
      721 gcgctggggg cggcagccgg ggtcaacctt ctggcagctc ccgcgaggtg cgctctgtgg
      781 cccgggcacc tctggaagaa gctgccggag gccagtctga gccctggttc gcggctcgac
      841 ccctgcagcc aggtgctgag gacgaggagg agctcgaatc tcaggagctg cctcggggat
      901 ccagcgggga tacctccctg ccctccggag ccccggcccc gtggcagcct tctccgtccc
      961 cgcaaccgcc ctcgtccccg ccccctgccc agcaagagga acccagcaca gaggaggtgc
     1021 tgttgcggat tccggccctc tccagggacc tgtacctgct gctccggaga gatggccgct
     1081 tcctggcgca gcgctttgca gtggagcagt ggccaaaacc aggtcctgat cccacccgag
     1141 caacagttga ccctcgccct cctatgccgt cagacgcttc ctgcttttac accgggacgg
     1201 tgctgcgcca tcctggctct ctggcctctt tcagcacctg tggaggtggc ctgatgggct
     1261 ttatacaact caatgaggac ttcatattca tcgagccatt caatgataca atggccataa
     1321 taggtcaccc acaccgttta tacaggcaga aaaggtcctc agaagaaaga gtcacagaga
     1381 agtctgctgc tcaccgccac cactgtggtg tcatttcaga taaaggaaga ccaaggtcta
     1441 aaaaattagc agaaaacaga cgagaaaaac ggtattccta caaattaccc caggattaca
     1501 acatcgagac tgtagtagtt gcagaccctg caatggtttc ctaccacgga gcagacgcag
     1561 ctaggagatt cattctgact atcctaaata tggtttttaa ccttttccaa cacaagagtc
     1621 tgggcgtgca ggtcaacctt cgtgtgataa agctcatcct tctccacgaa acaccagcag
     1681 atctgtatat tgggcaccat ggagagaaaa tgctggagag tttctgtaag tggcaacatg
     1741 aagagtttgg caggaagaac gatatccatt tagagatgtc gacgagctgg ggagaagatg
     1801 ttgcttctgt ggatgctgct attctaataa caaggaaaga tttctgcgtc cacaaagatg
     1861 agccctgtga taccgtgggt atcgcttact tgaacggcat gtgtagtgag aagagaaaat
     1921 gcatcatcgc tgaagacaat ggcctgaacc tggccttcac aattgcccat gaaatgggtc
     1981 acaacatggg catcaaccat gacaatgacc acccatcctg tgctgatggt cttcatatca
     2041 tgtctggtga atggatcaaa ggacaaaatc ttggtgacgt ttcatggtcc aggtgcagca
     2101 aggaagattt ggaaagattt ctcaggtcaa aggccagtag ctgtttgttg catacagatc
     2161 ctcagagtct cagttcagtg ctggttccct caaaactgcc agggatggcg tacactgcag
     2221 acgaacagtg ccagatcctc tttgggcctt tggcttcttt ttgtcaagag atgcagcacg
     2281 ttatctgcac tggtctgtgg tgcagagtgg agggggacac agagtgcagg accaagcttg
     2341 acccaccgat ggatgggact gactgcgacc ctggcaagtg gtgtaaggct ggagaatgca
     2401 cccgcaggac ccctgcaccc gagcacttgg ctggagagtg gagcacatgg agttcctgta
     2461 gtcgaagctg cggttctggg gtcagcagtc gagagcgcaa gtgtcctggg ctaggttctg
     2521 aagcaaggga ttgtaatggc cccagaaaac aatacagaat atgtgagaat ccaccttgtc
     2581 ctgcaggttt gcctggattc agagactggc aatgtcaggc ctatagtgtt agaacttcgt
     2641 acccaaagca tgcacttcag tggcaagccg tcttcgacga agaaaaacca tgtgccttgt
     2701 tttgctctcc tgttggaaaa gaacagcccg ttcttctatc cgaaaaggtg ctggatggaa
     2761 cttcttgtgg atatcagggg ttagatgtat gcgcaaatgg caggtgccag aaagctggtt
     2821 gtgatggttt attggggtct ctagccaggg aagatcattg tggcgtatgt aacggcaatg
     2881 gaaaatcatg caaagtcatt aaaggcgatt ttaatcacac cagaggggca ggctatgtgg
     2941 aagtgctggt gatacctgca ggagcgagaa gaatcaaagt cgtggaggaa aaacccgcac
     3001 atagctactt agctcttcga gatgccagca agcagtctat aaacagtgac tggaagatag
     3061 aacattctgg agcattcagt ctagctggaa ctacagtcca ttacataaga cgaggcctgt
     3121 gggagaagat ctctgccaaa ggacccacaa ccacaccttt acatctcctg gtgctcctat
     3181 ttcaagatca gaattacggt cttcactatg aatacactgt gccatcagac cctcttccag
     3241 ataaccagag ctctaaggag tcgggacccc tcttcatgtg gacacacgca ggctgggggg
     3301 attgcaatgc cacgtgtgga ggaggagaga ggaagacaac agtgtcctgc acaaaaatca
     3361 tgaacaagaa tatcagcctt gtggacaaca agaaatgcaa ggacctgacc aagccagagc
     3421 cccagattcg aaagtgcaat gagcagcctt gtcaaacaag gtggatgatg acagaatgga
     3481 ccacctgttc acgaacatgt ggaaaaggag tccagagtag acaagtggcc tgtacccggc
     3541 aactggaaaa cggaacccta attagagcct gggagaggga ctgcataggg ccaaagcctg
     3601 ctaccatgca gcgctgtgag ggtcaggact gcatgacggt gtgggaggcc ggagtgtggt
     3661 ccgagtgctc ggtgaagtgt ggcaaaggcg tgcggcatcg taccgtgagg tgcactaacc
     3721 caagaaaaaa gtgtgtcctc tccaccagac ccagggaggt ggaggactgt gaggattact
     3781 caaaatgcta cgtgtggcga gtgggtgact ggtccaagtg ctccattacc tgtggcaaag
     3841 gcatgcagtc tcgtgttatc cagtgcatgc ataagatcac aggaaggcat gggaatgaat
     3901 gcttttcttc agagaaacct gcagcataca ggccatgtca ccttcagccc tgtaatgaga
     3961 agattaacgt aaacacaata acgtcaccga gactggctgc cctgaccttc aagtgcctgg
     4021 gagaccagtg gccagtgtac tgcagagtga tacgggagaa gaatctttgt caggacatgc
     4081 gttggtacca gcggtgctgt gagacatgca gggacttcta tgcccaaaag ctacggcaga
     4141 agagttgacc tctggcaaac tggctgactg gctcttagct gttttgctat tgcattattt
     4201 ataaacacac acactagcat gtttttcaga ccaaatacta tcagattaca tataatttaa
     4261 tcaaattaat ttatttgcct gtgaggcatc taatgtggtg tttgttttgg tcatacaagc
     4321 attttggttt tatattatga agcttcataa ataattttaa tatgaattag taagttgggt
     4381 ctagtaaact aataagaaaa aaagaaaatt tttttcattt agggctgtct ctaaggtgct
     4441 attttctctc caccaaaacc attaagttat ccagtgtgta ctctacctta gcatgatagc
     4501 ttagctatat atgcagaaaa tgacatattt tcttgtgtcc tgctgcagaa tctgcccatt
     4561 ttctgttatt ggcaggagat gtgtaaacag aacaaacctc acagtcttga aaagtttgag
     4621 agaatgtata atgaatttga ttcagatttc gaggcgagca taggagacat tctactgtaa
     4681 tgataccttt atattaataa tggaagagtc aagacagaga ctttgatcat gtcagtggac
     4741 acgcacttga acacaagtac cgtgagcctg aagcactgta ttgatgtaca ctgaatcacc
     4801 gttgcgctgt tggtgtaggt gtagagacgc tgcgatagaa gtggcagctc ctataaaacc
     4861 tgtattattg taacatgcca ttagactgtg gcttttaaaa ggtatttcca acagagaaag
     4921 catggatgca cccacatcct tccatcccct agaagattta caaatgagga ccatactttg
     4981 actcagaaat catatgaaca atggtagtaa atatttttcc ttttatttcc ctaggaaata
     5041 agaaaaagaa aatgagattc agataatatt ttgatagttt cgttgtgttt tgccttttta
     5101 aaagaaataa aatttataat tcttctgaaa a
//
