LOCUS       XM_218753               6092 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ADAM metallopeptidase with
            thrombospondin type 1 motif, 17 (Adamts17), transcript variant X1,
            mRNA.
ACCESSION   XM_218753
VERSION     XM_218753.10
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_218753.11.
            
            On Jan 21, 2021 this sequence version replaced XM_218753.9.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6092
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6092
                     /gene="Adamts17"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif, 17; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 8 ESTs, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 29 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:293004"
                     /db_xref="RGD:1308783"
     CDS             133..3501
                     /gene="Adamts17"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 17 isoform X1"
                     /protein_id="XP_218753.6"
                     /db_xref="GeneID:293004"
                     /db_xref="RGD:1308783"
                     /translation="MCDGTLLPPLVLSLLLLVWGLDPGTVVGDAAADVEVVLPRRLRP
                     DDVHLQLLPGAAGLRQWRRPRASPGDPRAGPGERALLLHLPAFGRDLYLQLRRDLRFL
                     SPGFEVEEAGVSGRSGHPAELCFYSGQVLGHPGSLVSLSACGAAGGLVGLIQLEQELV
                     FIQPLNNSGGPFSRREHLIRRKWSSTSGLATKVEGPRQHCKVVTEEKPRKGKLSWDWR
                     ERRNAIRLTNEHTVETLVVADADMVQYHGAEAAQRFILTVMNMVYNMFQHQSLGIKIN
                     IQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPGGKDDTPPV
                     DAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHN
                     LGMNHDDDHSSCAGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLITD
                     PRSQHALRLPHKLPGMHYSANEQCQILFGTNATFCKNMEHLMCAGLWCLVEGDTSCKT
                     KLDPPLDGTECGADKWCRAGECVSKTPIPEHVDGDWSPWSAWSMCSRTCGTGARFRQR
                     KCDNPPPGPGGTHCQGASVEHAACENLPCPKGVPSFRDQQCQAHDRLSSKKRGLLTAM
                     VVDDKPCELYCSPLGKESPLLVADRVLDGTPCGPYETDLCVYGRCQKIGCDGIIGSAA
                     KEDRCGVCSGDGKTCRVVKGDFSHSRGTGYIEAVVIPAGARRIRVVEDKPAHSFLALK
                     DSSKRSINSDWKIELPGEFQIAGTIVRYVRRGLWEKFSAKGPTTVPLHLMVLLFHDQN
                     YGIHYEYTIPVNQSTENQSEPAKPQDALFLWTHSGWEGCSVQCGGGERRTIVSCTRIV
                     NKTTTLVNDSDCPQASRPEPQVRRCNSHPCQSRWVAGQWSPCSATCEKGIQHREVTCV
                     YQLQNGTHVTTRPIYCSEPRPTPVQSCEGQDCLSIWEASEWSECSANCGKGIRKRTVT
                     CTNSQGKCDAATRPKAEEACEDYSGCYEWKTGDWSKCSSTCGKGLQSRVVQCMHKVTG
                     RHGSECPTLSKPAAYRQCHQEVCNEKINVNTITSPRLAALTYKCTRDQWTVYCRVIRE
                     KSLCQDMRWYQRCCQTCRDFYANKMRQPPSPPSL"
ORIGIN      
        1 taccatgttg ggtttgtccg cagcgctaat tactttttcc aaaggctgca gggcttcact
       61 ccggctggcg tcgccgcctc acgcgcccct gctctgccgc tacggtcttg ggggctgctg
      121 gtcccgagta ccatgtgtga cggcaccctg ctgccccctc tcgtcctgtc cttgctgctg
      181 ctggtgtggg gtttggaccc gggcacagtt gtcggcgacg cggcggccga cgtggaggtg
      241 gtgctcccaa ggcggctgcg ccccgacgac gtgcacctgc agctgctgcc gggagcagcg
      301 gggctccggc agtggcggcg accgcgagca tctccaggcg accctcgagc gggaccggga
      361 gagcgcgccc tgctgctgca cctgccggcc tttgggcgag acctatacct gcagctgcgt
      421 cgcgacctgc gcttcctgtc cccaggcttc gaggtggagg aggcgggtgt ctcagggcgc
      481 agcggacacc ctgcggagct gtgcttctac tccggacaag tcctgggcca cccgggctcc
      541 ctcgtctccc tcagcgcctg tggcgccgcc ggcggcctgg ttggcctcat ccagctcgag
      601 caggagctag tgttcatcca gcccctcaac aactcagggg gcccattcag cagaagagag
      661 catctgatca gacgcaagtg gtcctctacc tccggcctag ctaccaaggt cgagggaccc
      721 aggcagcact gcaaagtagt gacagaagag aagcccagga aaggcaagct gtcttgggat
      781 tggagagagc ggaggaatgc catccggctc accaatgagc acacggtgga gacccttgtg
      841 gtggccgatg ctgacatggt gcagtaccac ggggcagagg ctgcacagag attcatcctc
      901 accgtcatga acatggtata caacatgttt cagcaccaga gtctcgggat taaaattaac
      961 attcaagtta ccaagctggt ccttctgcga caacgccctg ccaagttatc cattgggcac
     1021 catggtgagc ggtccctgga gagcttctgt cactggcaga atgaggagta cggaggtgct
     1081 cggtaccttg gcaataacca ggtgccagga gggaaggatg atacgccccc tgtggatgct
     1141 gctgtgtttg tgaccaggac agatttctgc gttcacaaag atgaaccttg tgacaccgtt
     1201 ggaattgctt acttaggagg cgtgtgcagt gctaagagga agtgtgtgct cgccgaagac
     1261 aatggtctca atttggcctt taccatcgca catgagctgg gtcacaattt gggaatgaac
     1321 cacgacgatg accactcatc ttgtgctggc cggtcacaca tcatgtcggg agaatgggtg
     1381 aaaggccgga atcccagcga cctctcttgg tcgtcctgta gtcgagatga ccttgagaac
     1441 tttctcaaat ccaaagtcag tacatgttta ctgatcactg accccaggag ccagcatgcc
     1501 ctgcgccttc cacacaagct gccaggcatg cactacagcg ccaacgagca gtgccagatt
     1561 ctgtttggca ccaacgctac cttctgcaaa aacatggagc atctgatgtg tgctgggctg
     1621 tggtgtctgg tagagggaga cacatcctgc aagaccaagc tggaccctcc cctggatggc
     1681 actgagtgtg gagcagacaa gtggtgccgg gctggagagt gtgtgagcaa gacgcccatc
     1741 ccagagcatg tggacgggga ctggagtccg tggagcgcct ggagcatgtg cagccgaacg
     1801 tgtggtacag gagctcgatt ccggcagagg aaatgtgaca atcccccccc tgggcctgga
     1861 ggcacacact gccagggcgc cagcgtagaa catgcagcct gcgagaacct gccctgcccc
     1921 aagggtgtgc ccagcttccg ggaccaacag tgccaagccc atgaccgact gagcagcaag
     1981 aagagaggcc tgttgacagc aatggtggtt gatgataagc cctgtgaact ctactgctca
     2041 cccctcggga aggagtcccc gctgctggtg gctgacaggg tcctggatgg cacaccctgc
     2101 ggaccctacg agactgacct ctgcgtgtat ggcagatgcc agaaaattgg ctgcgacggc
     2161 atcattgggt ctgcagctaa agaagacagg tgtggtgtct gcagtgggga tggcaagacc
     2221 tgccgtgtgg tgaagggtga cttcagccac tcccggggga caggttacat cgaagctgtt
     2281 gtcattcctg ctggagctcg gcggatccgt gtggtggaag acaaacctgc ccacagcttc
     2341 ctggctctca aagactccag taagagatct atcaacagcg actggaagat agaactccct
     2401 ggagagttcc agattgctgg tacaattgtc cgttatgtga gaagaggcct gtgggagaag
     2461 ttctcagcca agggacccac cacagtgccc ctgcatctga tggtgctgtt gtttcatgac
     2521 cagaattatg gaattcatta cgaatacacc atacctgtaa accagagcac agaaaaccag
     2581 agtgagcccg ccaagccaca ggatgccctg ttcctctgga cacacagtgg ctgggaaggg
     2641 tgcagcgtgc agtgtggagg aggagaacgc agaaccatcg tatcgtgcac acggattgtt
     2701 aacaagacca caaccctggt gaatgacagt gactgtcccc aagcaagccg ccctgagccc
     2761 caggtccgac ggtgtaactc tcacccatgc cagtcccggt gggtagctgg tcagtggagc
     2821 ccctgctcag cgacctgtga gaagggcatc cagcatcggg aggtgacatg cgtgtaccag
     2881 ctacagaacg gcacccacgt cactactcgg cccatctact gctcagaacc ccggcccaca
     2941 ccagtacaga gctgtgaagg ccaggactgc ctgtctatct gggaggcttc agagtggtca
     3001 gagtgctctg ccaactgcgg caaagggatc cggaaacgaa ctgtgacatg caccaactcc
     3061 caagggaaat gcgacgcggc cacacggcca aaggcggagg aggcgtgtga ggactactcc
     3121 ggctgctatg agtggaaaac aggagactgg tctaagtgct catccacctg cgggaagggg
     3181 ctccagtcca gagtggtaca gtgcatgcac aaggtcaccg gacgccatgg cagtgagtgc
     3241 ccgactctct caaagccagc agcctacaga cagtgccacc aggaggtctg caatgagaag
     3301 atcaatgtga acaccatcac ctcccctcgc cttgctgctc tgacctacaa atgcacccgg
     3361 gaccagtgga cggtgtactg ccgggtcatc cgagagaaga gcctctgcca ggacatgcgg
     3421 tggtaccagc gctgctgcca gacctgccgg gacttctacg caaacaagat gcgccagccg
     3481 ccctctcctc cgagcttgtg acgcacagtg tggtgcttgc tcaacgctct gactcaaggt
     3541 ctgaggcgtg gcagtgagtg gagagccctc accctagcca aaagcacacc agccctgcag
     3601 ccaggacccc caaagcactc ctctcttccc actgcaaggc cgcctcaagc attcagctgc
     3661 ctagagctag agagcaggct tgacactgcc attggtcctt tgaacgtaat atattgttaa
     3721 cagccactgg atggctttct aaggaaaaac tacacaagag tcataaagta attttaattt
     3781 ccaagctcct atgtacctca aagggggaca cctctggcag ataataattg ttcacacata
     3841 cacacacaca cacacacaca cacacacaca cagagagaga gagagagaga gagagagaga
     3901 gagagagaga gagagagaga gagaacgaga acatttagtg cttctgttct ggtgttgcat
     3961 ttgaattcgg gcttgatgta gctttgtgga aatgagatac cgcatttaag ggggctctct
     4021 cctgaaagtc agcagtgccc tgatcaacca gcctccacta atggcttctc tggaagaaag
     4081 atgagctacc ttcctacaaa cacaagaatc aagacttggt ctctgcccat ctcaaaaaca
     4141 tagcctcgca agccttagaa attgccttag aaatcttgcc cctgagagtt caaatctgaa
     4201 tagaccaaca agaaatccag tgccacacag ctctgcacac cacctgtgtg ggagaacgtt
     4261 cccgaagagg tgaatttggg aaggaaggtg tctgcttttc ggagctcagc tgtgtatctc
     4321 acagggaaac aggggagtct ctcttcaagg tgctatgaaa tgggacattc atgcatggtc
     4381 catggggtcg cctcctgaca taagatgccc tcagctcccc aggggtgtgc ctcctggcac
     4441 atccactctg gccagcactc gctttggctt tgtaccttat atacatgcta caacttggca
     4501 aagtagcttt ccattgacat tggcctctcc tctgaagtta ggatgacgct tgggacatct
     4561 gaggacacac atcagtcctg ggttctgcag cataaggctt gacttcaata tctggacaca
     4621 aggaagatgt gccgggactt gtggaggaat accatacagc caaaattgct acacatccat
     4681 caggccgcct tccagccaat gtgtcacggt tagcgccttc actgttcata gctgtcatca
     4741 gtgacctatc tggacgtggc atggaaagac agagaaggtc ctctcttccc tccccatgcc
     4801 atcactctag ccacagaact ttcccatctc cagaaggcca gagaagtgcc agactgacct
     4861 ctccaagagc agaccagctg atagactcct ggctacccag gaggctggct ttgccccacc
     4921 tctcgagggt tttcatgggt gcttgtgaac taccttgaga ggcccatctt ctcctggttg
     4981 cagacggaag ctctctcgtt ggcagtttcc atgggatcat ctccgagtgc ttcttgattt
     5041 attactggtg ctgtttctgt ttttcgtttg gtttagttct gtcttagttt tcagtagccc
     5101 atcacacaga cgaggtcagg gtggcaggga aactgtttgg ttccacttga actgagaaag
     5161 gagtgttgag aagactcctt aggtgctctg agagtgtcag ggtgaagtaa ccctctggtg
     5221 gtcaccccgg tgctgtgcta aacactgccc caccccaccc ccagctcagg cctggttacc
     5281 agcagacccc cccccaggct atttcgaaaa cccataaatt ctagggagct tcggaggtgg
     5341 aagggaaggt gctatcaatt ttccctccac catacagctt ctgttagttt acccaaagac
     5401 attcatattt tggagccaga gagcaatgag agccagctca gggggccaca tagtcttcct
     5461 tgtggatctg cagagaccca cctaggcaga gcaagtcccc atcattgtgc actgtccccg
     5521 gtgcctctga tgtccccacc ccaagctgtc tgtcacctga aggagcccca caccataaac
     5581 gttaagcccc ccccacgcat gcgctttctg agcaaatgct ggtatcatca ctgaactcca
     5641 ccacgctttc attctgccat caaagctctg gggtcacaat ggtgatgtcc ctgtgttaga
     5701 cccacactgt cactcgagta ctgtaccccc gtgggcccac agatgtgtca ctagcgtctc
     5761 tcagtcttac ggtgctattc gtactggtgc aggacaaacc actcgccgtc gtctgtggct
     5821 tgatagatca gaacacagga gaggagccgt ggtggtgacc taagctctgc tctttcgcca
     5881 ttttaaagtc aaatgtatat agttcccact agttaactca cactcagtac tgtatatgtg
     5941 ggctctgttt tgtgttgttt tagtttgggg tgctggttgt gaaagtacgc agaagaatag
     6001 acgacaaaca tcggacgccc ttagacatga aaaaactcat cgttccattg ggagcaagtt
     6061 ggacatgtgt aataaaatgt ttttccataa ca
//
