LOCUS       XM_006233879            4693 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ADAM metallopeptidase with
            thrombospondin type 1 motif, 13 (Adamts13), transcript variant X1,
            mRNA.
ACCESSION   XM_006233879
VERSION     XM_006233879.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006233879.4.
            
            On Jan 21, 2021 this sequence version replaced XM_006233879.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4693
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4693
                     /gene="Adamts13"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif, 13; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 ESTs, 4 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 40 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:102554393"
                     /db_xref="RGD:1311594"
     CDS             21..4469
                     /gene="Adamts13"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 13 isoform X1"
                     /protein_id="XP_006233941.3"
                     /db_xref="GeneID:102554393"
                     /db_xref="RGD:1311594"
                     /translation="MDEKFPGGTVGSQATWDGTCRDREPLTSLSSCRPGVSSQNESQS
                     PGLPSGHRLPVLRMSQLCLWLPCQPFLAASIRGILTGAIFILGCWGLSDFQKSFLQDL
                     EPKDLSSSFSRHTAPLTGHPSSHLQRLRQRRTSEDILHLELLVAVGPDVYQAHQEDTE
                     RYVLTNLNIGSELLRNPSLGAQLQVHLVKLIILSDSENTPNITTNITSSLMSVCEWSQ
                     TINPHDDRDPSHADLIIYITRFDLELPDGNQQVRGVTQQGGACSPSWSCLITEDTGFD
                     LGVTIAHEIGHSFGLDHDGAPGSGSTCEARGHVMASDGAVPAGGALEWSTCSQRQLQH
                     LLSTGQMHCLWDPPGLQSGLTWHQLVAQPGLFYSADDQCRVAFGAGAVACTFSREGLD
                     VCQALSCHTDPLDQSSCSRLLVPLLDGTECGVEKWCSKARCRSLAELAPVAVVHGHWS
                     SWGPHSPCSRSCGGGVITRRRWCNNPRPAFGGRACVGEDLQAKMCNTQACEKTQLEFM
                     SEQCAQTDRHPLQLSQGSASFYHWDAAVQYSQGDTLCRHMCWAVGESFIVSRGDSFLD
                     GTRCVPNGPREDGTVSLCLLGSCRTFGCDGKMDSQQVWDACQVCGGDNSTCTSQNGSF
                     TAGRAREYVTFLIVTPNMTSAHVINHRPLFTHLAVRIQDHYIVSGKSSMSPNVTYPSL
                     LEDYRVEYRVTLTEDQLPRLEEIHIRGPVRDDIEIQVYRRYGGEYGGLTHPDITFTYF
                     QRKQQAAWVWAAKRGPCSVSCGAGLRWVTYSCQDQAQNKWVRNAQCQGSPQPPAWQEP
                     CVSAPCPPHWVADDFGPCSVSCGGGLRERSLRCVEAHNGFLKTLPPAPCRAVAQQPAG
                     EVENCNSQPCPTGWEVSDPSPCVSSACEPGLESGSGTCVPRVGDSEKPAMAGPCRPDD
                     MSPVPEPCVRTTCSPGSGPVDTMSLGEEASSPVGSGKPSSQAEHVWTPLVGLCSISCG
                     KGLKELYFLCMDSVLKMPVQEELCGLASKPPSRWEVCRARPCPARWETRVLAPCPVTC
                     GGGRVPLAIHCVQLDHGRPVSVPHSKCWPAPRPGSFEDCSPEPCPARWKVLPLGPCSA
                     SCGLGTATQMVACVQLDQGHDNEVDETFCKALVRPPASVPCLIADCAYRWHISTWTEC
                     SVSCGDGIQRRHGTCLGPQAQVPVPANFCQHLPKPVTVRGCWAGPCAGQKISSSLPHK
                     EATLPSQTLAAVTAASLQWSQPQAQAHSLFPDSQSLGLQETLEEPGACGRQYLEPTGT
                     IDMRGQGQLDCVVAIGRPLGEVVTLQILESSLKCRAGELLLLWGKFTWRKMCWKMSGR
                     TFSTKANTVVVRQHRVLPGGGVLLLYRSQPAPGTFYKECDRQLFGPRGEITSPSLSPD
                     GRKAGTCRVFVSVAPQARIAIRALASDMGTASEGTSANYVSIRDIHGLKTTTFWGQQV
                     LYWESEGSEAELEFSHGFLEAHASFQGQYWTIPPRTPEQVNSVALS"
ORIGIN      
        1 gcaagagtgt tttggagcga atggatgaga aattcccagg aggtacagtg ggaagccagg
       61 caacttggga cggtacttgc agagatagag aaccacttac ctctctctcc agctgcaggc
      121 caggcgtttc gtctcaaaac gaatcccagt caccagggct cccgtccggc catcggctgc
      181 ctgttctaag gatgagccag ctttgcttat ggttgccgtg ccagcctttt cttgctgcca
      241 gtatcagagg aatcctcacg ggcgccatct tcattctggg ctgctggggg ctctctgatt
      301 tccagaagag ttttcttcaa gatctggagc ccaaggactt atcttcctcc ttcagccgcc
      361 atactgctcc actcacaggc catccttcct ctcacctcca gagactgaga cagaggagga
      421 cttcggagga cattctgcac ctagaactcc tggtagctgt gggccccgat gtttaccagg
      481 ctcaccagga ggacacagag cgctacgtgc tcaccaacct caatatcggg tcagaactgt
      541 tgagaaaccc gtccctaggg gctcagctcc aagtgcacct ggtgaagctg atcattctct
      601 cggactcaga gaatactccg aatatcacga ccaacatcac ctcatccttg atgagtgtct
      661 gcgagtggag ccagacgatc aatccccatg atgacaggga cccaagtcat gctgacctga
      721 tcatctatat aaccaggttt gacctggagc tgccggatgg taaccagcag gttcggggag
      781 tcacccaaca gggtggtgcc tgctctcctt cctggagttg ccttatcact gaggacactg
      841 gcttcgatct gggggtcacc attgcccacg agattggaca cagctttggg ctggaccatg
      901 atggtgctcc aggcagtggc agcacctgcg aggcccgtgg ccatgtgatg gcatctgacg
      961 gcgcagtgcc tgctggaggg gccctggagt ggtccacctg cagccaaagg cagctgcagc
     1021 acctgctcag cacagggcaa atgcactgcc tctgggaccc gcccgggctg cagtcaggac
     1081 tcacatggca ccagctggtg gcacagcctg gcctcttcta cagtgcagat gaccagtgcc
     1141 gtgtggcttt cggcgccggg gctgtcgcct gcaccttctc cagggagggt ctggatgtat
     1201 gccaggctct gtcctgtcac acagaccccc tggaccaaag cagctgcagc cgcctccttg
     1261 ttcctctcct ggacgggaca gaatgtggtg tagagaagtg gtgctctaag gctcgctgtc
     1321 gctccctagc tgagctggct cctgtggctg tggtacatgg acactggtct agctggggcc
     1381 cccacagtcc ttgctctcga tcctgtggag gaggtgtgat caccaggaga cggtggtgca
     1441 acaaccccag gcctgcattt gggggacgtg catgtgtggg cgaggacctc caggctaaga
     1501 tgtgcaacac gcaggcttgt gagaagactc agctggagtt catgtcagag cagtgtgccc
     1561 agacagacag acatccactg caactttccc aaggcagtgc ctccttctac cactgggatg
     1621 ctgctgtgca gtatagtcaa ggggatactc tgtgcagaca catgtgctgg gctgttggag
     1681 aaagtttcat tgtcagccgt ggggacagtt tcctcgatgg gacccgttgt gtgccaaatg
     1741 gtcctcggga ggatgggacc gtgagcctct gtttgttggg tagctgcagg acctttggct
     1801 gtgatggcaa gatggactcc cagcaggttt gggatgcgtg ccaggtgtgt ggaggagaca
     1861 acagcacctg cacttcccaa aatggctctt tcacagctgg gagagccaga gagtatgtca
     1921 cgttcctgat agtcactccc aacatgacca gcgcacacgt catcaaccac aggcctctct
     1981 tcacacactt ggcggtgagg atccaggacc actacattgt gtcagggaag agcagcatgt
     2041 cgcctaacgt cacgtaccct tcccttctgg aggactaccg cgtggagtac agagtaactc
     2101 tcactgagga ccagctgccc cgcttagagg agattcacat ccggggacct gtccgggatg
     2161 acattgagat ccaggtgtac agacgatatg gaggagaata tgggggtctt acacacccag
     2221 acatcacctt tacctacttc caacggaagc agcaggcagc ctgggtatgg gccgctaagc
     2281 gtgggccctg ctcagtgagc tgtggggcag ggctgcgctg ggtgacctac agctgccagg
     2341 atcaagctca aaacaagtgg gtgaggaacg cccagtgcca agggagcccg cagccacctg
     2401 catggcagga gccttgtgtc tctgccccgt gccctccaca ctgggtagct gacgactttg
     2461 gcccatgcag cgtgtcttgt ggcggaggcc ttcgggagcg gtcactgcgc tgtgtagagg
     2521 cccacaatgg cttcttaaag acgttgccgc cagccccatg cagagcagta gcccagcagc
     2581 cagcaggaga ggtagaaaac tgcaactccc agccctgccc cactggatgg gaggtgtcag
     2641 accctagccc ttgcgtgtca tctgcgtgtg aacccggtct ggagtcaggg agtgggacat
     2701 gtgtgcccag ggtgggtgac tcagagaagc cagcgatggc aggcccctgc cgcccggatg
     2761 acatgtcacc tgtgccggag ccctgcgtta ggaccacatg ttctccaggc tcgggtccgg
     2821 tggacaccat gtctctggga gaggaggctt catccccagt gggcagtggc aagccaagct
     2881 ctcaggctga acatgtgtgg actcctctgg tggggctgtg ctccatttct tgtgggaaag
     2941 gtctgaagga gctgtatttc ctgtgcatgg attctgtcct caagatgcct gtccaggaag
     3001 agctatgtgg cttggccagt aagcccccaa gccggtggga ggtctgcagg gctcgcccat
     3061 gtcctgctcg gtgggagact cgagtcttgg caccgtgtcc ggtgacctgt ggcggggggc
     3121 gagtgccgct ggccattcat tgtgtgcagc tggaccacgg gcgccctgtg tctgtacctc
     3181 actccaagtg ctggccagca cctaggccag gctccttcga ggactgcagc cctgagcctt
     3241 gtcctgctag atggaaagtc ctgccccttg gcccgtgctc agccagctgt ggccttggca
     3301 ctgccacaca aatggtggcc tgcgtgcagc ttgaccaagg ccatgacaat gaggtggatg
     3361 aaactttctg taaggctctg gtgcggcccc ccgccagtgt tccctgcctc attgctgact
     3421 gtgcataccg gtggcacatc agcacctgga cagagtgctc cgtctcctgt ggggatggca
     3481 tccagcgccg gcatggcacc tgcctcggac cccaggctca agtgcctgtg ccagccaact
     3541 tctgccagca cctgcccaag ccagtgactg tgagaggctg ctgggctgga ccctgtgcag
     3601 ggcagaagat ctccagctcg ctgcctcaca aggaagctac tcttcccagc cagaccctgg
     3661 ctgcggttac tgctgcctct ctgcaatggt cccagcccca agcccaggcc cacagccttt
     3721 tcccagactc ccagtctctg gggctccagg aaaccctgga agagcctgga gcctgtggaa
     3781 ggcaatacct ggagcccaca ggaaccattg acatgcgagg tcaaggacag ctagactgtg
     3841 tggtagccat cgggagacct ctaggtgaag tggtgaccct ccaaatcctc gagagctccc
     3901 tcaagtgcag agcaggggag ctgctgctgc tctggggtaa gttcacatgg cggaagatgt
     3961 gctggaagat gtctggcagg actttcagca caaaagccaa cacggtggtg gtgaggcagc
     4021 atcgtgtgct gccgggaggt ggagtgctgc tactgtaccg gagccaacct gccccaggga
     4081 ccttctacaa agaatgtgac aggcagctct ttggacctcg gggtgaaatc acgagtccct
     4141 cactgagccc agacgggagg aaggcaggaa cctgcagggt ctttgtcagt gtggccccac
     4201 aggcccgaat tgccatccgt gccctggcca gtgacatggg cactgcttct gaggggacca
     4261 gtgccaacta tgtctcgatc agggatatcc acggtctgaa gactacaaca ttttgggggc
     4321 agcaggtgct ctactgggag tccgaaggca gtgaggctga actggagttt agccatggct
     4381 tcctggaggc gcatgccagt ttccagggcc agtattggac catcccaccg aggacaccgg
     4441 aacaggtcaa cagcgtggct ctgtcctaga tttctctcca acggccagct ggaaagagag
     4501 gcagccctac tccggaaagg gtgaccatcc ccggactatg caactctagc ctcttgagag
     4561 gttcaaatgc ctgccagccg aagggaaccg cttttagtga ccttttccag gtgcagaagg
     4621 gcggggactg ggagttggag atcagaaaag caatcccagt cctcagggct aataaaggat
     4681 acaggaaacc aga
//
