LOCUS       XM_039079031            4059 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ADAM metallopeptidase with
            thrombospondin type 1 motif, 10 (Adamts10), transcript variant X2,
            mRNA.
ACCESSION   XM_039079031
VERSION     XM_039079031.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039079031.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4059
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4059
                     /gene="Adamts10"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif, 10; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 27 ESTs, 2 long SRA reads, 15
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 76 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:314655"
                     /db_xref="RGD:1598320"
     CDS             250..3564
                     /gene="Adamts10"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 10 isoform X1"
                     /protein_id="XP_038934959.1"
                     /db_xref="GeneID:314655"
                     /db_xref="RGD:1598320"
                     /translation="MASACQILRWALALGLGLTFKVTHAFRSQDELLSSLESYEIAFP
                     TRVDHNGAMLAFSPPALRRQRRGVGAAAESRLFYKVAAPSTHFLLNLTRSPRLLAGHV
                     SVEYWTREGLAWQRAARAHCLYAGHLQGQAGSSHVAISTCGGLHGLIVADDEEYLIEP
                     LQGGPKGRRGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPAR
                     PQGNETERGQLGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQ
                     DSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVSHSGHGNAIPEN
                     GVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAH
                     EIGHTFGMNHDGVGNGCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLG
                     LCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRC
                     ITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRSCGGG
                     VSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTNDCPPGSQDFREMQCSEFDSVPFRGK
                     FYTWKTYRGGGVKACSLTCLADGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGC
                     DRVLGSDLREDKCRVCGGDGSACETIEGVFSPALPGTGYEDVVWIPKGSVHIFIQDLN
                     LSLSHLALKGDQESLLLEGLPGTSQPHRLPLAGTTFHLRQGPDQAQSLEALGPINASL
                     IIMVLAQAELPALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQVVECRNQL
                     DSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRR
                     VSAAEEKALDDSACPQPRPPVLEACQGPMCPPEWAALDWSECTPSCGPGLRHRVVLCK
                     SADQRSTLPPGHCPPAAKPPSTMRCNLRRCPPARWVASEWGECSTQCGLGQQQRTVRC
                     TSHTGQPSRECTEALRPSTMQQCEAKCDSVVPPGDGPEECKDVNKVAYCPLVLKFQFC
                     SRAYFRQMCCKTCQGR"
ORIGIN      
        1 tttttataac cttggcaggc tgctcaggaa gtgagtgcct tcccgcgccc cctcccccgg
       61 ccacgccacc gcgcgctcgc tccctccctt cctgtgcgcg gggcggtgag tctgtgcggc
      121 tacggcagac cggaggctcc aggcacgcag gggaccagtg atgctgccca gactgtgaac
      181 aggggaggca gcactgtagg ggctgccagc agccggggct ggggagagac atgtggacac
      241 gtagccccta tggcttctgc ctgccagatc ctccgctggg cccttgccct ggggctgggc
      301 ctcacattca aggtcacgca tgccttcaga tctcaagatg agctcctgtc cagtttggag
      361 agctatgaga ttgccttccc aactcgagtg gaccacaacg gggcaatgct ggccttctca
      421 ccacctgccc tccggaggca gcgtcggggt gtaggggctg cagctgagtc ccgtctattc
      481 tacaaggtgg ccgcacccag cactcacttc ctgctgaacc tgacccgcag cccccgtctc
      541 ctggcagggc acgtctcggt ggaatactgg acacgggaag gcctagcctg gcagagggct
      601 gcccgggccc actgcctcta cgctggccac ttgcaaggcc aggctggtag ctcccatgtg
      661 gccatcagca cctgtggggg cctgcatggc ctgattgtgg cagatgacga agagtacctg
      721 attgagcccc tgcaaggtgg acccaaaggt cgccgtggcc cagaagagag tggcccccac
      781 gtagtataca agcgttcctc tctgcgtcac ccccatctgg acacagcctg tggagtgaga
      841 gatgagaaac catggaaggg tcgtccatgg tggttgcgca ccctgaagcc accgcctgcc
      901 aggccccagg ggaatgaaac tgagcgaggc cagctgggcc tgaagcgatc agtcagccga
      961 gagcgctatg tggagaccct ggtggtggcc gacaagatga tggtggccta ccatgggcgg
     1021 agagatgtgg agcaatatgt gttggccatc atgaatattg ttgccaaact tttccaggac
     1081 tcgagtctgg gaaacatcgt caacatcctc gtcactcgcc ttatcctgct cacagaggac
     1141 cagcccaccc tggagatcac ccatcatgct gggaagtcac tggacagctt ctgtaagtgg
     1201 cagaaatcaa tcgtgagcca cagtggccat ggcaacgcca tcccagagaa cggtgtggca
     1261 aaccatgaca cagctgtgct catcacacgc tatgacatct gcatctacaa gaacaaaccc
     1321 tgcggcactc taggcctggc ccctgtgggt ggaatgtgtg agcgtgagag gagctgcagc
     1381 atcaatgaag atattggcct ggccacagct ttcaccattg cccacgagat cgggcacaca
     1441 ttcggcatga accacgatgg tgtgggaaac ggctgcgggg ctcgaggtca ggaccctgca
     1501 aagctcatgg ctgcccatat caccatgaag actaatccat tcgtgtggtc atcatgcagt
     1561 cgagattaca tcaccagctt tctggactca ggcctggggc tttgcttgaa caaccggcct
     1621 cccagacagg acttcgtgta cccaacggtg gctcctggcc aggcctatga tgctgatgag
     1681 cagtgccgat tccagcatgg agtcaaatcg cgtcagtgta aatacgggga ggtctgcagt
     1741 gaactgtggt gtctgagcaa gagcaatcgg tgcatcacca atagcatccc agctgctgag
     1801 ggaacactgt gccaaacaca cactatcgac aaagggtggt gctacaaacg agtgtgtgtc
     1861 ccctttgggt ctcgaccaga gggtgtagac ggggcctggg gcccatggac tccatggggt
     1921 gactgcagca ggtcatgtgg cggtggtgtg tcatcttcca gtcgtcactg cgacagtccc
     1981 aggccaacca ttgggggcaa gtactgtctg ggcgagagac ggaggcaccg gtcctgcaac
     2041 accaatgact gtccacctgg ctcccaggac ttcagagaaa tgcagtgctc tgaatttgac
     2101 agtgttcctt tccgtggaaa attctacaca tggaagacgt accgaggagg gggcgtgaag
     2161 gcctgctcgc tgacttgcct agcagatggc ttcaactttt acacggagag agcagcagct
     2221 gtggtggatg gaacaccctg ccgccctgac acagtggaca tttgtgtcag cggcgagtgc
     2281 aagcatgtgg gctgtgacag ggtcctgggt tctgatctcc gagaggacaa atgcagagtg
     2341 tgtgggggtg acggcagtgc ctgtgagacc attgaggggg tcttcagccc agctttgcca
     2401 ggaactgggt atgaggacgt cgtctggatc cccaaaggct cagtccacat tttcatccaa
     2461 gatctgaacc tgtcccttag tcacctggcc ctaaaggggg accaggagtc tctgctactg
     2521 gaggggctac ctgggacctc ccaacctcac cgccttcccc tggctgggac cacatttcat
     2581 ctacggcagg gaccagacca ggcccagagc ctagaagccc tgggacccat taatgcatct
     2641 ctcatcatca tggtgctggc ccaggcagag ttgcctgctc tccgctaccg cttcaatgca
     2701 cccattgccc gggatgcact gcctccctac tcctggcact atgccccctg gaccaaatgc
     2761 tcagctcagt gtgcaggcgg cagccaggtc caagtggtgg agtgccgaaa tcagctggac
     2821 agctcagcag tggccccaca ctactgcagt gcccacagca aattacccaa gaggcagcgt
     2881 gcctgcaaca cagaaccatg cccaccagat tgggttgtag gtaactggtc ccgctgcagc
     2941 cgtagctgtg atgctggtgt gcgtagccgc tcagtggtgt gccaacgccg agtgtctgct
     3001 gcagaggaga aagccttaga tgacagcgcc tgtccacagc cacgcccacc tgtgctggag
     3061 gcctgccaag gcccaatgtg cccccctgag tgggcagccc tggactggtc tgagtgtacc
     3121 ccaagttgtg ggcctggtct ccgccaccga gtggtccttt gtaagagtgc agatcaacga
     3181 tccactctgc cccctgggca ctgccctcct gcagccaagc caccatctac tatgagatgc
     3241 aacttgcgcc gctgccctcc cgcccgctgg gtggccagtg agtggggtga gtgttccaca
     3301 cagtgtggcc tcggccagca gcagcgcaca gtgcgttgca ccagccacac tggccagcca
     3361 tctcgagagt gcactgaggc cctgcggccg tccaccatgc agcagtgtga ggccaagtgt
     3421 gacagtgtgg tgccgcctgg agatggccca gaagaatgca aggatgtgaa caaggtggct
     3481 tactgccccc tggtgctcaa atttcagttc tgtagccgag cctacttccg ccagatgtgc
     3541 tgcaaaacct gccaaggccg ctagggtacc tggaaccaac ctggagcaca ggctgagggc
     3601 tcctggctag ggggtggaga agagctggct acccagggac cctcttcagt gtcttgccaa
     3661 gttgacaatg aaaggagagg actgcccctt gtcgcacaca cttttaagtc cctaacactc
     3721 ccccaccctt tgatcggaat atgtactgtg aagagtgggg gtggggagag ggtatgctgg
     3781 taccctgccc cccagcactg ttctatccct acactctgag ctgggggaat ttatatctgc
     3841 tatgggggga gtgggcttga taccacctcc ctgtcaccct cccccagact gaccaagggg
     3901 aagatctacc ccaacctctg ccctgcctgc ccaggggggg agtccaacat ccaggccatc
     3961 ccccatcatg gtgctaacaa gccctgccct ggggcccaca cactcctcac caagaagcct
     4021 tccattaata aagttctgtc ttgtgtagat ttccgctca
//
