LOCUS       XM_017594822            3217 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ADAM metallopeptidase with
            thrombospondin type 1 motif, 10 (Adamts10), transcript variant X8,
            mRNA.
ACCESSION   XM_017594822
VERSION     XM_017594822.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017594822.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3217
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3217
                     /gene="Adamts10"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif, 10; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 30 ESTs, 2 long SRA reads, 1
                     Protein, and 98% coverage of the annotated genomic feature
                     by RNAseq alignments, including 143 samples with support
                     for all annotated introns"
                     /db_xref="GeneID:314655"
                     /db_xref="RGD:1598320"
     CDS             736..2622
                     /gene="Adamts10"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 10 isoform X5"
                     /protein_id="XP_017450311.1"
                     /db_xref="GeneID:314655"
                     /db_xref="RGD:1598320"
                     /translation="MMLMSSADSSMESNRVSEVCSELWCLSKSNRCITNSIPAAEGTL
                     CQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRSCGGGVSSSSRHCDSPR
                     PTIGGKYCLGERRRHRSCNTNDCPPGSQDFREMQCSEFDSVPFRGKFYTWKTYRGGGV
                     KACSLTCLADGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDK
                     CRVCGGDGSACETIEGVFSPALPGTGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQ
                     ESLLLEGLPGTSQPHRLPLAGTTFHLRQGPDQAQSLEALGPINASLIIMVLAQAELPA
                     LRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQVVECRNQLDSSAVAPHYCSA
                     HSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRRVSAAEEKALDDS
                     ACPQPRPPVLEACQGPMCPPEWAALDWSECTPSCGPGLRHRVVLCKSADQRSTLPPGH
                     CPPAAKPPSTMRCNLRRCPPARWVASEWGECSTQCGLGQQQRTVRCTSHTGQPSRECT
                     EALRPSTMQQCEAKCDSVVPPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKT
                     CQGR"
ORIGIN      
        1 gtggagcaat atgtgttggc catcatgaat attgtcaggt tgccaaactt ttccaggact
       61 cgagtctggg aaacatcgtc aacatcctcg tcactcgcct tatcctgctc acagaggacc
      121 agcccaccct ggagatcacc catcatgctg ggaagtcact ggacagcttc tgtaagtggc
      181 agaaatcaat cgtgagccac agtggccatg gcaacgccat cccagagaac ggtgtggcaa
      241 accatgacac agctgtgctc atcacacgct atgacatctg catctacaag aacaaaccct
      301 gcggcactct aggcctggcc cctgtgggtg gaatgtgtga gcgtgagagg agctgcagca
      361 tcaatgaaga tattggcctg gccacagctt tcaccattgc ccacgagatc gggcacacgt
      421 gaggccaggg gacacaagat aggggaggat aagagaatct gggttgggtt cccttagtgc
      481 ctggcagagc tgatacctct ctcctcagat tcggcatgaa ccacgatggt gtgggaaacg
      541 gctgcggggc tcgaggtcag gaccctgcaa agctcatggc tgcccatatc accatgaaga
      601 ctaatccatt cgtgtggtca tcatgcagtc gagattacat caccagcttt ctggactcag
      661 gcctggggct ttgcttgaac aaccggcctc ccagacagga cttcgtgtac ccaacggtgg
      721 ctcctggcca ggcctatgat gctgatgagc agtgccgatt ccagcatgga gtcaaatcgc
      781 gtcagtgagg tctgcagtga actgtggtgt ctgagcaaga gcaatcggtg catcaccaat
      841 agcatcccag ctgctgaggg aacactgtgc caaacacaca ctatcgacaa agggtggtgc
      901 tacaaacgag tgtgtgtccc ctttgggtct cgaccagagg gtgtagacgg ggcctggggc
      961 ccatggactc catggggtga ctgcagcagg tcatgtggcg gtggtgtgtc atcttccagt
     1021 cgtcactgcg acagtcccag gccaaccatt gggggcaagt actgtctggg cgagagacgg
     1081 aggcaccggt cctgcaacac caatgactgt ccacctggct cccaggactt cagagaaatg
     1141 cagtgctctg aatttgacag tgttcctttc cgtggaaaat tctacacatg gaagacgtac
     1201 cgaggagggg gcgtgaaggc ctgctcgctg acttgcctag cagatggctt caacttttac
     1261 acggagagag cagcagctgt ggtggatgga acaccctgcc gccctgacac agtggacatt
     1321 tgtgtcagcg gcgagtgcaa gcatgtgggc tgtgacaggg tcctgggttc tgatctccga
     1381 gaggacaaat gcagagtgtg tgggggtgac ggcagtgcct gtgagaccat tgagggggtc
     1441 ttcagcccag ctttgccagg aactgggtat gaggacgtcg tctggatccc caaaggctca
     1501 gtccacattt tcatccaaga tctgaacctg tcccttagtc acctggccct aaagggggac
     1561 caggagtctc tgctactgga ggggctacct gggacctccc aacctcaccg ccttcccctg
     1621 gctgggacca catttcatct acggcaggga ccagaccagg cccagagcct agaagccctg
     1681 ggacccatta atgcatctct catcatcatg gtgctggccc aggcagagtt gcctgctctc
     1741 cgctaccgct tcaatgcacc cattgcccgg gatgcactgc ctccctactc ctggcactat
     1801 gccccctgga ccaaatgctc agctcagtgt gcaggcggca gccaggtcca agtggtggag
     1861 tgccgaaatc agctggacag ctcagcagtg gccccacact actgcagtgc ccacagcaaa
     1921 ttacccaaga ggcagcgtgc ctgcaacaca gaaccatgcc caccagattg ggttgtaggt
     1981 aactggtccc gctgcagccg tagctgtgat gctggtgtgc gtagccgctc agtggtgtgc
     2041 caacgccgag tgtctgctgc agaggagaaa gccttagatg acagcgcctg tccacagcca
     2101 cgcccacctg tgctggaggc ctgccaaggc ccaatgtgcc cccctgagtg ggcagccctg
     2161 gactggtctg agtgtacccc aagttgtggg cctggtctcc gccaccgagt ggtcctttgt
     2221 aagagtgcag atcaacgatc cactctgccc cctgggcact gccctcctgc agccaagcca
     2281 ccatctacta tgagatgcaa cttgcgccgc tgccctcccg cccgctgggt ggccagtgag
     2341 tggggtgagt gttccacaca gtgtggcctc ggccagcagc agcgcacagt gcgttgcacc
     2401 agccacactg gccagccatc tcgagagtgc actgaggccc tgcggccgtc caccatgcag
     2461 cagtgtgagg ccaagtgtga cagtgtggtg ccgcctggag atggcccaga agaatgcaag
     2521 gatgtgaaca aggtggctta ctgccccctg gtgctcaaat ttcagttctg tagccgagcc
     2581 tacttccgcc agatgtgctg caaaacctgc caaggccgct agggtacctg gaaccaacct
     2641 ggagcacagg ctgaggcagg ggaaatccca ctggagaggg cctgaggggg gatgggaggg
     2701 ctgggattga agggtgagac gcagttgaaa gttatttatt gggtaacccc tacagggctc
     2761 ctggctaggg ggtggagaag agctggctac ccagggaccc tcttcagtgt cttgccaagt
     2821 tgacaatgaa aggagaggac tgccccttgt cgcacacact tttaagtccc taacactccc
     2881 ccaccctttg atcggaatat gtactgtgaa gagtgggggt ggggagaggg tatgctggta
     2941 ccctgccccc cagcactgtt ctatccctac actctgagct gggggaattt atatctgcta
     3001 tggggggagt gggcttgata ccacctccct gtcaccctcc cccagactga ccaaggggaa
     3061 gatctacccc aacctctgcc ctgcctgccc agggggggag tccaacatcc aggccatccc
     3121 ccatcatggt gctaacaagc cctgccctgg ggcccacaca ctcctcacca agaagccttc
     3181 cattaataaa gttctgtctt gtgtagattt ccgctca
//
