LOCUS       XM_017594820            4032 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ADAM metallopeptidase with
            thrombospondin type 1 motif, 10 (Adamts10), transcript variant X1,
            mRNA.
ACCESSION   XM_017594820
VERSION     XM_017594820.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_017594820.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4032
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4032
                     /gene="Adamts10"
                     /note="ADAM metallopeptidase with thrombospondin type 1
                     motif, 10; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 33 ESTs, 3 long SRA reads, 15
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 27 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:314655"
                     /db_xref="RGD:1598320"
     CDS             123..3437
                     /gene="Adamts10"
                     /codon_start=1
                     /product="A disintegrin and metalloproteinase with
                     thrombospondin motifs 10 isoform X1"
                     /protein_id="XP_017450309.1"
                     /db_xref="GeneID:314655"
                     /db_xref="RGD:1598320"
                     /translation="MASACQILRWALALGLGLTFKVTHAFRSQDELLSSLESYEIAFP
                     TRVDHNGAMLAFSPPALRRQRRGVGAAAESRLFYKVAAPSTHFLLNLTRSPRLLAGHV
                     SVEYWTREGLAWQRAARAHCLYAGHLQGQAGSSHVAISTCGGLHGLIVADDEEYLIEP
                     LQGGPKGRRGPEESGPHVVYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPAR
                     PQGNETERGQLGLKRSVSRERYVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQ
                     DSSLGNIVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVSHSGHGNAIPEN
                     GVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSINEDIGLATAFTIAH
                     EIGHTFGMNHDGVGNGCGARGQDPAKLMAAHITMKTNPFVWSSCSRDYITSFLDSGLG
                     LCLNNRPPRQDFVYPTVAPGQAYDADEQCRFQHGVKSRQCKYGEVCSELWCLSKSNRC
                     ITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRSCGGG
                     VSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTNDCPPGSQDFREMQCSEFDSVPFRGK
                     FYTWKTYRGGGVKACSLTCLADGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGC
                     DRVLGSDLREDKCRVCGGDGSACETIEGVFSPALPGTGYEDVVWIPKGSVHIFIQDLN
                     LSLSHLALKGDQESLLLEGLPGTSQPHRLPLAGTTFHLRQGPDQAQSLEALGPINASL
                     IIMVLAQAELPALRYRFNAPIARDALPPYSWHYAPWTKCSAQCAGGSQVQVVECRNQL
                     DSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSRCSRSCDAGVRSRSVVCQRR
                     VSAAEEKALDDSACPQPRPPVLEACQGPMCPPEWAALDWSECTPSCGPGLRHRVVLCK
                     SADQRSTLPPGHCPPAAKPPSTMRCNLRRCPPARWVASEWGECSTQCGLGQQQRTVRC
                     TSHTGQPSRECTEALRPSTMQQCEAKCDSVVPPGDGPEECKDVNKVAYCPLVLKFQFC
                     SRAYFRQMCCKTCQGR"
ORIGIN      
        1 cccgttgtgc gtgtgttgcg ttggggacca gtgatgctgc ccagactgtg aacaggggag
       61 gcagcactgt aggggctgcc agcagccggg gctggggaga gacatgtgga cacgtagccc
      121 ctatggcttc tgcctgccag atcctccgct gggcccttgc cctggggctg ggcctcacat
      181 tcaaggtcac gcatgccttc agatctcaag atgagctcct gtccagtttg gagagctatg
      241 agattgcctt cccaactcga gtggaccaca acggggcaat gctggccttc tcaccacctg
      301 ccctccggag gcagcgtcgg ggtgtagggg ctgcagctga gtcccgtcta ttctacaagg
      361 tggccgcacc cagcactcac ttcctgctga acctgacccg cagcccccgt ctcctggcag
      421 ggcacgtctc ggtggaatac tggacacggg aaggcctagc ctggcagagg gctgcccggg
      481 cccactgcct ctacgctggc cacttgcaag gccaggctgg tagctcccat gtggccatca
      541 gcacctgtgg gggcctgcat ggcctgattg tggcagatga cgaagagtac ctgattgagc
      601 ccctgcaagg tggacccaaa ggtcgccgtg gcccagaaga gagtggcccc cacgtagtat
      661 acaagcgttc ctctctgcgt cacccccatc tggacacagc ctgtggagtg agagatgaga
      721 aaccatggaa gggtcgtcca tggtggttgc gcaccctgaa gccaccgcct gccaggcccc
      781 aggggaatga aactgagcga ggccagctgg gcctgaagcg atcagtcagc cgagagcgct
      841 atgtggagac cctggtggtg gccgacaaga tgatggtggc ctaccatggg cggagagatg
      901 tggagcaata tgtgttggcc atcatgaata ttgttgccaa acttttccag gactcgagtc
      961 tgggaaacat cgtcaacatc ctcgtcactc gccttatcct gctcacagag gaccagccca
     1021 ccctggagat cacccatcat gctgggaagt cactggacag cttctgtaag tggcagaaat
     1081 caatcgtgag ccacagtggc catggcaacg ccatcccaga gaacggtgtg gcaaaccatg
     1141 acacagctgt gctcatcaca cgctatgaca tctgcatcta caagaacaaa ccctgcggca
     1201 ctctaggcct ggcccctgtg ggtggaatgt gtgagcgtga gaggagctgc agcatcaatg
     1261 aagatattgg cctggccaca gctttcacca ttgcccacga gatcgggcac acattcggca
     1321 tgaaccacga tggtgtggga aacggctgcg gggctcgagg tcaggaccct gcaaagctca
     1381 tggctgccca tatcaccatg aagactaatc cattcgtgtg gtcatcatgc agtcgagatt
     1441 acatcaccag ctttctggac tcaggcctgg ggctttgctt gaacaaccgg cctcccagac
     1501 aggacttcgt gtacccaacg gtggctcctg gccaggccta tgatgctgat gagcagtgcc
     1561 gattccagca tggagtcaaa tcgcgtcagt gtaaatacgg ggaggtctgc agtgaactgt
     1621 ggtgtctgag caagagcaat cggtgcatca ccaatagcat cccagctgct gagggaacac
     1681 tgtgccaaac acacactatc gacaaagggt ggtgctacaa acgagtgtgt gtcccctttg
     1741 ggtctcgacc agagggtgta gacggggcct ggggcccatg gactccatgg ggtgactgca
     1801 gcaggtcatg tggcggtggt gtgtcatctt ccagtcgtca ctgcgacagt cccaggccaa
     1861 ccattggggg caagtactgt ctgggcgaga gacggaggca ccggtcctgc aacaccaatg
     1921 actgtccacc tggctcccag gacttcagag aaatgcagtg ctctgaattt gacagtgttc
     1981 ctttccgtgg aaaattctac acatggaaga cgtaccgagg agggggcgtg aaggcctgct
     2041 cgctgacttg cctagcagat ggcttcaact tttacacgga gagagcagca gctgtggtgg
     2101 atggaacacc ctgccgccct gacacagtgg acatttgtgt cagcggcgag tgcaagcatg
     2161 tgggctgtga cagggtcctg ggttctgatc tccgagagga caaatgcaga gtgtgtgggg
     2221 gtgacggcag tgcctgtgag accattgagg gggtcttcag cccagctttg ccaggaactg
     2281 ggtatgagga cgtcgtctgg atccccaaag gctcagtcca cattttcatc caagatctga
     2341 acctgtccct tagtcacctg gccctaaagg gggaccagga gtctctgcta ctggaggggc
     2401 tacctgggac ctcccaacct caccgccttc ccctggctgg gaccacattt catctacggc
     2461 agggaccaga ccaggcccag agcctagaag ccctgggacc cattaatgca tctctcatca
     2521 tcatggtgct ggcccaggca gagttgcctg ctctccgcta ccgcttcaat gcacccattg
     2581 cccgggatgc actgcctccc tactcctggc actatgcccc ctggaccaaa tgctcagctc
     2641 agtgtgcagg cggcagccag gtccaagtgg tggagtgccg aaatcagctg gacagctcag
     2701 cagtggcccc acactactgc agtgcccaca gcaaattacc caagaggcag cgtgcctgca
     2761 acacagaacc atgcccacca gattgggttg taggtaactg gtcccgctgc agccgtagct
     2821 gtgatgctgg tgtgcgtagc cgctcagtgg tgtgccaacg ccgagtgtct gctgcagagg
     2881 agaaagcctt agatgacagc gcctgtccac agccacgccc acctgtgctg gaggcctgcc
     2941 aaggcccaat gtgcccccct gagtgggcag ccctggactg gtctgagtgt accccaagtt
     3001 gtgggcctgg tctccgccac cgagtggtcc tttgtaagag tgcagatcaa cgatccactc
     3061 tgccccctgg gcactgccct cctgcagcca agccaccatc tactatgaga tgcaacttgc
     3121 gccgctgccc tcccgcccgc tgggtggcca gtgagtgggg tgagtgttcc acacagtgtg
     3181 gcctcggcca gcagcagcgc acagtgcgtt gcaccagcca cactggccag ccatctcgag
     3241 agtgcactga ggccctgcgg ccgtccacca tgcagcagtg tgaggccaag tgtgacagtg
     3301 tggtgccgcc tggagatggc ccagaagaat gcaaggatgt gaacaaggtg gcttactgcc
     3361 ccctggtgct caaatttcag ttctgtagcc gagcctactt ccgccagatg tgctgcaaaa
     3421 cctgccaagg ccgctagggt acctggaacc aacctggagc acaggctgag gcaggggaaa
     3481 tcccactgga gagggcctga ggggggatgg gagggctggg attgaagggt gagacgcagt
     3541 tgaaagttat ttattgggta acccctacag ggctcctggc tagggggtgg agaagagctg
     3601 gctacccagg gaccctcttc agtgtcttgc caagttgaca atgaaaggag aggactgccc
     3661 cttgtcgcac acacttttaa gtccctaaca ctcccccacc ctttgatcgg aatatgtact
     3721 gtgaagagtg ggggtgggga gagggtatgc tggtaccctg ccccccagca ctgttctatc
     3781 cctacactct gagctggggg aatttatatc tgctatgggg ggagtgggct tgataccacc
     3841 tccctgtcac cctcccccag actgaccaag gggaagatct accccaacct ctgccctgcc
     3901 tgcccagggg gggagtccaa catccaggcc atcccccatc atggtgctaa caagccctgc
     3961 cctggggccc acacactcct caccaagaag ccttccatta ataaagttct gtcttgtgta
     4021 gatttccgct ca
//
