LOCUS       NM_001408681            2658 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ADAM metallopeptidase domain 24 (Adam24), mRNA.
ACCESSION   NM_001408681 XM_017600371
VERSION     NM_001408681.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2658)
  AUTHORS   Zhu,G.Z., Gupta,S., Myles,D.G. and Primakoff,P.
  TITLE     Testase 1 (ADAM 24) a sperm surface metalloprotease is required for
            normal fertility in mice
  JOURNAL   Mol Reprod Dev 76 (11), 1106-1114 (2009)
   PUBMED   19670298
REFERENCE   2  (bases 1 to 2658)
  AUTHORS   Han,C., Choi,E., Park,I., Lee,B., Jin,S., Kim,D.H., Nishimura,H.
            and Cho,C.
  TITLE     Comprehensive analysis of reproductive ADAMs: relationship of ADAM4
            and ADAM6 with an ADAM complex required for fertilization in mice
  JOURNAL   Biol Reprod 80 (5), 1001-1008 (2009)
   PUBMED   19129510
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Jun 22, 2022 this sequence version replaced XM_017600371.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.75071.1,
                                           SRR26360181.888507.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                JAXUCZ010000016.1  58287693-58287735   c
            44-2658             JAXUCZ010000016.1  58281748-58284362   c
FEATURES             Location/Qualifiers
     source          1..2658
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.1"
     gene            1..2658
                     /gene="Adam24"
                     /note="ADAM metallopeptidase domain 24"
                     /db_xref="GeneID:290774"
                     /db_xref="RGD:1309066"
     exon            1..43
                     /gene="Adam24"
                     /inference="alignment:Splign:2.1.0"
     exon            44..2658
                     /gene="Adam24"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..2402
                     /gene="Adam24"
                     /note="a disintegrin and metalloprotease domain 24
                     (testase 1); a disintegrin and metallopeptidase domain 24
                     (testase 1); disintegrin and metalloproteinase
                     domain-containing protein 24; a disintegrin and
                     metalloproteinase domain 24"
                     /codon_start=1
                     /product="disintegrin and metalloproteinase
                     domain-containing protein 24 precursor"
                     /protein_id="NP_001395610.1"
                     /db_xref="GeneID:290774"
                     /db_xref="RGD:1309066"
                     /translation="MVTVREALVHARITLLQVWWRVLLFSSVWPMTLCTEHKAPPETV
                     IPVRVIVSSKEMSLTGWMSYSLHFGGHRHIISLKSKNFLVSRQLPVFTYSDQGVLFED
                     RPFVQTDCYYLGFVDEDPESMAALTTCFGGFQGILQINDTTYKIKPKTPSFTFEHLLY
                     KIDSEETQLHPMRCGLTDEEIAGQVRLQENDKSTLMQSIYGSWWSHGLYIKLALVIDH
                     EQFLYRKSNTSLVLKDVFNIMNGINLSLLSVDINVALLGLTIWTQRNPIPVQDIYTLL
                     PAFCLWKTMNFNSQMAYDIAHLFVNYTFGDYFGIAFVGTVCNKTFGCGVDRLFGDNFL
                     TIGHIVAHEIGHNLGMPHDGILCSCGEGPCLMSATMESSKKLSNCSYEFLWANIAKKS
                     CLQREPSSSDIFPMKICGNGVVDDGEECDCGSQSCGRNSRCCLPTCILKSGAKCASGL
                     CCNFKCQIQPSGTLCRTKENECDLPEWCNGTSKECPEDTFVQAGTSCLGNGYCYEKRC
                     NSHDDHCKRVFGEHAMKASDRCYKELNTRGDRFGNCGLKNKGYVRCETSDILCGRIQC
                     AKVKTFPILESHYTVHWTRFNDASCWSTDYHLGMKIADLGDIKDGTNCGPQHVCISRK
                     CVNKPSWKSDCSPETCNMRGICNNKQHCHCDFGWSPPLCVDNGTGGSIDSGSPAPEDP
                     NANKRKGIGKFIILLLPIIFVVVVLFLLFYLFRTNRLSLGGDKQAKKGEEAKPPEEEA
                     "
ORIGIN      
        1 gagtcatgac taagaccaca ccaagatatt atcactacat ctgtcttcct gctctgatgg
       61 atctactctt ccagaagaca gactattaag ggtctgtgct gcatgagatc tagacaaagg
      121 aagtacatgg acaagaggac cacatcccat cctcctttgt ttgcttcctc tagtaggaca
      181 tggtgactgt gagggaggct ctggttcacg caaggatcac tctccttcag gtatggtgga
      241 gggtgttgct cttttcctct gtatggccca tgactttgtg tactgaacac aaagcacccc
      301 cagagacagt gatacccgtg agggtaattg tctctagtaa agagatgagt cttacaggct
      361 ggatgtccta cagtctgcac tttggaggcc acagacacat tatctccttg aagtccaaga
      421 actttttggt atcaagacag ctccctgtgt tcacatacag tgaccaaggt gttctctttg
      481 aggacagacc ttttgtccag actgactgtt actaccttgg ttttgtggat gaagatccag
      541 aatccatggc tgctcttaca acctgttttg ggggctttca aggcatatta cagataaatg
      601 atacaactta taaaattaag cccaagaccc cctctttcac atttgaacat ctgctttaca
      661 agatagacag tgaagaaact caattacacc ccatgagatg tggattaaca gatgaagaaa
      721 tagcagggca agtgagactt caagaaaatg ataagtccac tctaatgcaa agcatctatg
      781 ggtcatggtg gtctcatgga ttgtatatta aactggcatt ggttatagac catgaacaat
      841 tcctttatcg gaaaagtaac acttctcttg tgttaaaaga tgtattcaac attatgaatg
      901 ggataaatct ctccttactt tcagttgata ttaatgtggc tttacttggt cttactattt
      961 ggactcaacg aaatcccata ccagtgcaag acatatatac tctcttgcca gcattttgtt
     1021 tgtggaagac aatgaacttt aattctcaga tggcatatga tattgcacat ctcttcgtga
     1081 attatacttt tggtgactat tttggcatag cctttgtggg aactgtatgc aataagacat
     1141 ttggttgtgg agttgatagg ctctttggag acaatttcct taccattgga catattgtgg
     1201 cccacgagat aggtcacaat ttgggcatgc cacatgatgg gatactttgt tcttgtggag
     1261 agggaccatg tttgatgtct gctacaatgg agagttccaa aaaactcagc aactgtagtt
     1321 acgaattctt gtgggccaac atagccaaaa aaagctgcct acagagggag cccagctctt
     1381 cagatatctt cccaatgaag atctgtggga acggtgtagt tgatgatggc gaggagtgtg
     1441 actgtggatc tcaaagctgt ggacgtaata gtaggtgttg tctgcctacc tgtattctga
     1501 agtctggagc taaatgtgct tctggactat gctgtaactt caaatgccaa attcagccat
     1561 ctggcactct gtgtagaacg aaggagaatg aatgtgatct tccagaatgg tgcaatggga
     1621 cttcaaagga gtgccctgag gatacatttg tacaggctgg gacttcttgc cttggtaatg
     1681 gctactgcta tgaaaaaaga tgtaatagcc atgacgacca ctgcaagaga gtttttggcg
     1741 aacatgccat gaaagcatct gacagatgct acaaggagct caatactcgt ggtgatcgct
     1801 ttggtaactg tggactcaag aacaaggggt atgtgagatg tgagacctca gacatcctct
     1861 gtgggaggat tcagtgtgcc aaagtgaaaa catttcctat tctggaaagt cattacactg
     1921 ttcactggac tcgtttcaat gatgcttcct gctggagtac cgactaccac ttggggatga
     1981 aaatcgctga ccttggtgac ataaaagatg gcacaaactg tggtccacag catgtgtgca
     2041 tcagcagaaa gtgtgttaat aagccaagtt ggaaaagtga ttgttcacca gagacttgca
     2101 acatgagagg aatctgcaat aataaacagc actgtcattg cgattttggc tggagcccac
     2161 cactctgtgt ggacaatggg actggaggaa gcattgacag tggcagtcct gcacccgagg
     2221 accctaacgc aaacaaaagg aaaggcatag gaaaattcat aattttgcta cttcctatta
     2281 tttttgtggt tgtagttttg tttctattgt tttacctgtt tagaaccaat agactatcac
     2341 ttggaggaga taaacaggct aaaaaaggtg aagaggccaa acccccagaa gaggaagcat
     2401 aagaaaagcc agtagaggaa gagtaggcta aataaccaga caaggattaa gagagtaaac
     2461 gaaaccatca gacaagaaag aagaggctaa accatccaac gaggaagaag agactaaatc
     2521 caccagatta gggagagtac caactcaatt tcaacagctt cacttcttca acgtcaacca
     2581 acacagaaca gaaaaatcta atgagttgtc aaaataatct ttaaatttaa tgaaatatac
     2641 cacatggtaa tatttagc
//
