LOCUS       XM_039108569            9370 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ADAM metallopeptidase domain 22
            (Adam22), transcript variant X9, mRNA.
ACCESSION   XM_039108569
VERSION     XM_039108569.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039108569.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9370
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..9370
                     /gene="Adam22"
                     /note="ADAM metallopeptidase domain 22; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 34 ESTs, 6 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     13 samples with support for all annotated introns"
                     /db_xref="GeneID:57033"
                     /db_xref="RGD:1585016"
     CDS             308..3046
                     /gene="Adam22"
                     /codon_start=1
                     /product="disintegrin and metalloproteinase
                     domain-containing protein 22 isoform X9"
                     /protein_id="XP_038964497.1"
                     /db_xref="GeneID:57033"
                     /db_xref="RGD:1585016"
                     /translation="MQAVAAAFFWLLCVLGTYPLARCGRAGDASLRELERGDGNRFLE
                     RQSTVPLRLIYRLGGEDETQHEQLNTRVRGDPGGRQPTHVDKASFRVDAFGTSFILDV
                     LLNHELLSSGYVERHIEHGGKVVENKGGEHCYYQGQIRGNPASFVALSTCHGLHGMFY
                     DGNHTYLIEPEENEMSQESQFHSVYKSRLLEFPLDDLPSEFQRINITAPQFTLKPRLK
                     RRKRQLLRFPRNVEEETKYIELMIVNDHLMFKKHRLSVVYTNTYAKSVVNMADVIYKD
                     QLKTRIVLVAMETWAADNKFAISENPLVTLREFMKYRRDFIKEKADAVHLFSGSQFES
                     SRSGAAYIGGICSLLRGGGVNEFGKTDLMAVTLAQSLAHNIGIISDKRKLASGECKCE
                     DTWSGCIMGDTGYYLPKKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIE
                     TGEECDCGTPAECALEGAECCKKCTLTQDSQCSDGLCCKKCKFQPLGTVCREAVNDCD
                     IREICSGNSSQCAPNVHKMDGYSCDGTQGICFGGRCKTRDRQCKYIWGQKVTASDRYC
                     YEKLNIEGTEKGNCGKDKDTWTQCNKRDVLCGFLLCTNIGNIPRLGELDGEITSTLVV
                     QQGRTLNCSGGHVKLEEDVDLGYVEDGTPCGPQMMCLEHRCLPMASFNFSTCLSNKAG
                     TVCSGNGVCSNELKCVCNRHWTGADCGTHFPHNDDAKTGITLSGNGVAGTNIIIGIIA
                     GTILVLALILGITAWGYKNYREQRSNGLSHSWSERIPDTKHISDICENGRPRSNSWQG
                     NVGGNKKKIRGKRFRPRSNSTEREPQAPEPGHSLAQTSPGISPGGSDSPQTGSLDHST
                     QDGQHQENRTLSPAKSPSSSTGSIASSRKYPYPMPPLPDEEKTVNRQSARLWETSI"
ORIGIN      
        1 gtgcgcggcc gggtgcggcg cgaggggcaa gtgcaccagg cccgctgcgc acccggctcc
       61 gctccccgct gcgctgctgg ccgcccgcct tggcctccgc ctggggatga ggtgggaggc
      121 gctagaagcc acttagctac agcctggcgc ccgatgcggc gctcgctcgc tgcccacgcc
      181 accgaagcgc ccgccaggca caatgcagca ctgaggcagc ggcggctgcg gcagcggcgc
      241 gggctgggaa agggcggccg ggagcccgag cccggggccg ggaaacgagc agctgagcgc
      301 cgccaccatg caggcagtgg cggccgcgtt cttctggctg ctctgcgtct tggggaccta
      361 ccccctggcg cgctgcggtc gggcaggaga cgcctcactg agagaactgg agagggggga
      421 cggaaaccgc ttcctggagc gccagagcac cgtaccactg cgcctcatct accgcttggg
      481 cggcgaggac gaaactcagc acgagcagct caacacgcgg gtgcggggcg accctggcgg
      541 acggcagcct actcacgtgg acaaggcaag cttccgggtg gacgcctttg gaacctcctt
      601 cattctcgat gtcctgctga accacgagtt gctgtcctcc ggttatgtag agagacatat
      661 tgaacacgga ggcaaggtcg tggaaaacaa aggaggagaa cactgctatt accagggcca
      721 gattcgagga aaccctgcct cctttgttgc cctgtcaaca tgccacggac tccatgggat
      781 gttctatgat gggaaccaca catatctcat tgagcctgaa gaaaatgaga tgtcccaaga
      841 gtctcagttt cactccgtgt acaaatccag gctgcttgaa tttcccttgg acgaccttcc
      901 atctgaattt caacgcataa atatcactgc cccccagttt acactgaagc cgagactaaa
      961 gcggaggaaa agacagcttc ttcgatttcc tcggaatgta gaggaggaaa ctaaatacat
     1021 tgaactgatg atcgtgaatg atcatctcat gtttaaaaag caccggcttt ctgttgtata
     1081 tacaaatacc tatgcgaagt ctgtggtgaa catggcggac gtgatctata aggaccaact
     1141 taagactagg atagtgctgg ttgccatgga aacctgggct gctgacaaca agttcgccat
     1201 atctgaaaac ccactggtca ccttgcgtga attcatgaaa tacaggaggg attttatcaa
     1261 ggagaaggct gacgcagtcc atctcttctc gggcagtcaa tttgagagta gccggagcgg
     1321 ggcggcttat attggtggga tttgctcgct gctgagagga ggaggcgtga atgaatttgg
     1381 aaaaacggat ttaatggcag ttacactcgc tcagtcgcta gcccacaata tcggtataat
     1441 ctcagacaag aggaagttag cgagtggtga gtgtaaatgt gaggacacct ggtccgggtg
     1501 catcatggga gacaccgggt actatcttcc taaaaagttc actcagtgca atattgagga
     1561 atatcatgac ttcctgaata gcggtggagg ggcctgcctg tttaacaagc cttccaagct
     1621 tcttgatcct cccgagtgtg gaaacggctt cattgaaacc ggagaggagt gtgattgtgg
     1681 cacccctgcg gaatgtgccc ttgaaggggc agagtgttgt aagaaatgca ccttgaccca
     1741 ggactctcaa tgcagtgatg gcctgtgttg taaaaagtgc aagtttcagc ctctggggac
     1801 cgtgtgccgg gaggcagtga atgactgtga catccgtgaa atatgttcag gaaattcgag
     1861 ccagtgtgcc cccaatgtgc ataaaatgga tggatattcg tgtgatggta ctcagggaat
     1921 ttgctttgga ggaagatgta aaaccagaga tagacaatgc aaatacatct gggggcaaaa
     1981 ggtgactgca tctgacaggt actgctatga gaaactgaac attgagggga ctgagaaggg
     2041 caactgtggg aaagacaaag acacgtggac acagtgcaac aaacgggatg tgctctgtgg
     2101 tttccttcta tgcacaaata ttggcaacat cccaaggctc ggagagctcg atggtgaaat
     2161 cacgtccaca ctggttgtgc agcaaggaag gacattaaat tgcagcgggg gacatgtgaa
     2221 gcttgaagaa gacgtggatc ttggctatgt ggaagatggg acgccctgcg gccctcagat
     2281 gatgtgcttg gaacacaggt gtcttcccat ggcttccttc aacttcagca cttgcttaag
     2341 caataaagca ggcactgtgt gctcaggaaa cggagtttgt agcaatgagc tcaagtgtgt
     2401 gtgcaacagg cactggacag gtgccgactg tggcacccac tttcctcaca atgatgatgc
     2461 taagactggc atcaccctgt ctggcaatgg tgttgctggc actaatatca taataggaat
     2521 aattgctggc accattttag tgctggccct catattagga ataacagcct ggggttataa
     2581 aaactaccga gaacagaggt caaatggact ctctcattct tggagtgaaa ggattccaga
     2641 cacaaaacat atttcagaca tctgtgaaaa tgggagaccc cgaagtaatt cctggcaagg
     2701 taacgtggga ggcaacaaaa agaagatcag agggaaaaga ttcagacctc gctctaattc
     2761 aactgagagg gagccccaag cacctgagcc tgggcactcc ctcgcccaga catccccagg
     2821 cataagccca gggggctctg acagccccca gacagggagt ctggatcaca gcacccaaga
     2881 tggccaacat caagaaaaca ggaccctgtc acctgccaag tctccttctt catcaactgg
     2941 gtctattgcc tccagcagaa aatacccata cccgatgccc ccgcttccgg atgaggagaa
     3001 gacggtgaac cgacagagtg ccaggctgtg ggagacatcc atttaagaac aactgtttac
     3061 atgtgacaca tcgaaactgt ttacttctac ttttatagaa acccagccac ccacaatcac
     3121 tgcaaatctg catctgcttt tcggacgatt tcaagaccct cttgcgatgc cagaggagag
     3181 gaagccacgg gtcatacctg gatagcatac tttctttttc tttttctttt ctttttcttt
     3241 ttttttgtca ttggcttaag gtttaaccaa atggtaaaga gaattactgg aacgtcacgc
     3301 tgcaacatgg aaccatttat ggcctggcat tgatatgtta attgataatc tgcatggcag
     3361 aaatatgtag accatcaata aaactaaccc acacgaccca acgttagcag gttttcccga
     3421 ggggacagaa gtggattcag aactgagcat tctgaatcac atcctcattg caagcagtaa
     3481 cgcccgtatg catgaagctt ctgtttatcg ttttccatat gcaaggaaac aacctctcct
     3541 aatagaaact agcatgcagg ggctgaggca tataggactc ttctgcagga ccgcaggact
     3601 gtaaagcttc cagaagccaa tatcccatat gctaccttta aacatgtatt tttatttttt
     3661 tttacttttc atatttatat tagcatacag ggacgactgt acatatgtaa acatttttaa
     3721 aacttaagaa gtaactgtta accgtaagtg tattttttgc caaatgccta caaacagtca
     3781 gtcacgatcc tatcgctgtc ctccatccag tgtcttcgaa gtataagtgg atgatattgt
     3841 aaatagagtg gtcagtgctg taagagtatc tctccccaac cggtgtttgt ctaaaacgtg
     3901 caatttccct tttcaaagtg tgtacagtct ggaagaggtt ttcttgagca agacatccaa
     3961 atgctcaaac ttctagcctc tgcatcttgc cgaaggaaga gtccagatgt gaggtagcca
     4021 tgccgctcca ggacaccctg gagccgacag gctctctggg attctgccag cccatccact
     4081 ccatatctaa gacacatggt gcctgtcaca gtagctgttc tcaaccagta ccagggcata
     4141 tcaactaatc ttacctggag gtcatggagt ccccttctct ccagaaagtg tcttctgtga
     4201 ttggcaagat gtaccaaaga catggagcac agagtagagc gttccctctt gaccaaggcc
     4261 tgaggcttgt ctggtctgaa gtttgggttc cttgacagaa tccttttagc cattcttata
     4321 tgtgaaagga atgacttgct tccacaattt taacatgttt catcactagg gtgtaaatcc
     4381 cagcaggttg ttctgtctgg ctttgaacaa gatggtgtac ggaagcctga acaaggcata
     4441 aaaaaattaa gtaaagctac acagaggcag tgactgcaaa ggtaaccata agcccgcaga
     4501 ggaaagagcc tgtgttttgg gccctataac ctttgattca ctagaaaaaa aatgagtatt
     4561 ttatgtgaaa tcttgtcatt tacaacgaaa cattaatacc tgtttcaatg caatgttcag
     4621 tgttcaatgc aaaaagaaag tccctctaat gagatctgag gttgggaggc ccagtcacgt
     4681 gacctcctac ggaacactct tctgatttcc ctcttcttct tgctgtttta tgtgaggaat
     4741 gaaatcatca gacaagaact cagaaatgga ctctacattt gatttcttcc agatgcgtcc
     4801 agggacacaa tttgttccaa ctctgtgtag aattgtccta gatacccaaa ctgaagggac
     4861 aggctagaag gcagtggtat attcagctca tgtcttttgc aatggtccac tcttctaaaa
     4921 cactctgaag gtgttaggaa accaatttaa tcaggcaaaa ttaaacagtg aaaaaccatt
     4981 ttccatgaca ggcaaagata taggttgccg atggctcaat aaagcagtct cagataaagg
     5041 catggatgag tgttgaacaa tgtctccaca tagcttaagg taaggacgga aggacagaca
     5101 gatgacggat gaaaaagatg tagcaaaatg aagtgacttt tggacaagaa cacttcaaat
     5161 gtgcactgaa tgtttcttgg tatcgagtgt ataaaaggct aatgtaatat aaggtttatt
     5221 ttggctacag aagaaaaaag tttatatagc ttcgaatgaa aggtgcctca tgtaaatatg
     5281 ccgtgtagtt aatagttcgt tagataagct ctaacctgaa agaattcaca aatggttagc
     5341 cagtgagctg gttatctgtc tacctactgg tctttcctta ccttctcagt tgctttcacc
     5401 tggagttatg attgaaaatc aatatcatta tcatgtgcct ttggggagaa acggttgctc
     5461 cggcttgtaa tcatcttcag atgaaacagg aggaaaaggc tttgcttaac tcgcagagtg
     5521 attttagaaa tgtaacggct ttagtgttct aatctgggtc tctgtcttcc atgtctgagc
     5581 attcttagag ttgtttgtgg aattcacaga ctttagtctt gatgggtagc ctcgagaagt
     5641 atgcgtcatt ccatttaact acacgtgact gcattcactg aggtagacag agtagacctg
     5701 tggaatcaaa cccaagcaca gtgactattt catcctcaaa tgtgtatttt gaagaggaac
     5761 tttgaggctc cacggtggtt tgaatcgtgc gactaatatt cgtacttccc agtgtggtgt
     5821 ggggtcatca ctacacagag aagaaagcga tgtgttcatt ggatgtcgtt tctctttctc
     5881 atgatctcgg catcaaatag gactgcagat agcccggatg ccggagatgt cccattaagc
     5941 agatcatttc tgttccaatg aaaaggaaca tccaagtctt tgcactgtgt tagcagggga
     6001 ggcctgcagt agcagaatcc ttaaagaatg aactggccag attcactctt cccgggcact
     6061 ttccttagat gcaagtcttc ccccggaata agcgagatag aagatgactc atgcacagtc
     6121 tgcagaggga aatccgtgct gctgagatgg ggcggcatga aatttcttag tgttctgcag
     6181 tgcctggctt tgaagaacaa aagccaatca ccccaggccc ctacttagat gctaactgac
     6241 aagtaacctc ttcacagtta cccagcaaac attactgggg ataggaaacc agggcttagg
     6301 atgttgtctt agcaggtaag aggggtgctc ttttcacatc tcctcctggc tccacaaggc
     6361 ttttagaata acgtttgcac aggtcagtcc aatgtagtct tcatgcatga gagattggtg
     6421 gcatgtctaa aagaagccag tgtgaagata aaattaaata ttctctgtcc tccgcgggca
     6481 tggatgggga gtggaagatg gctgtgtttt ccagcacaga tccacatgct ttccctctgt
     6541 taaacacctt gcgtatctgc ctgacttcat tctgcctttt gccctagact tcagactttc
     6601 tgtagtgact ctacctgttg cccttttcag actttgtctt cttcttcttc tttttttttt
     6661 tctttttgta cccttaagcc aggcaaagtg tgatacctct acttgcttct tgcaaatttc
     6721 agtttgtcca cttcactctg tgagttttct gttgccctat agtcccatct taaccttagg
     6781 tctagacagt gctttagaga agccctgctc tgaagatgag attacttttt aatcttactt
     6841 agatgcaaag gaagggaagg ctgtttggca ggttgcagcg cataaagaga aggggacaga
     6901 gtctggaact gatgggagga aggagaagcc aggcctagct gcacagccac gcagggcacc
     6961 gctggctgct gctattggct gccatgtttg aagcattcat ctgagcagtg gcaagtttgc
     7021 ttgagcactg agacacttgg actcccatta gcagcacatt ctctacgtct tatgctcctc
     7081 cttgtctgtt ttgttttctt ctatagctgt cacctgcttc ccttccctcc ccaccccctg
     7141 cctcaaaggc agtcaaatct aatttttcat tcttattcta ctagctctgt gtgaaaagct
     7201 gacatttctg tagaagaggg cctaattggg gggctcaagt actgagtttc ttcctgtggg
     7261 atagttaaga ctacgctgac ttcagaggca gggtcctttc tctgggtgtg ggagcacagg
     7321 ggactggggt tctagactcg ccttattgta ttgcagagaa ctcagttgac gtttgtgaga
     7381 agagctgagg caggagtcca tctggctgtg tgtgagcagc gtgcggtaaa agtgccttgg
     7441 ccgctccctg ttggcacttg gcttacagca tatgctcttc aggacagaca ctttcagctc
     7501 aaagagtttc cctagcacag ctgcaggtac agaacaaaat tgtcccagac ttggagagca
     7561 gaaggtagta tttccatgcc tattttactc atggttttct ggtcctcaac atggagcacc
     7621 taaagtccgg cagctgaaaa tcaaaacttt tatcggacca ttattggttc tgtccttcaa
     7681 atccatggct attatattgg atggctgcat cgagaacctt cctactccca aagttccctg
     7741 ttcgggatct gtgcagcact tttcctcttg atcagaagca tcccctatca tacagaacag
     7801 gaccttctcg ggctaaaatg agaattggga gaaccacagg aacacagagc gggggaggtt
     7861 gtctttcatt tcctttcaat atgctggtct gattgtgcac cttggaaagt cactaagaga
     7921 tggctctcag ggtataaatc tcaggaagtt aataagcagc acagagtttt gagagatcct
     7981 gggtcatttc atcccagcct aggagcacag tggccatccc acacaaagcg tgcagaggac
     8041 tcaggaaggt caccagctat gctgcaggga actactgctg ccaagagcac acatgggctt
     8101 tgcagttttt tgtagtcttg ctttggaagt attttactgt ctggtgtccc ttgcattgtt
     8161 cacagacctg tgtcatactg ggaggggctt cagaagcagt aggtagcctg tgggatcaaa
     8221 ttcaagcaaa atgcatttta ttgtttcatt ttacgaaaag gcatacagtg agacaaagga
     8281 gtctttggcc accagtttct atgttcatga gctagtctcc ccgacatgta tgaagatgca
     8341 tgtgtatgca catcctgcat tcaacttaca acattttggg tcatggtttg ttttgatcgt
     8401 tgagttttaa aataatgaaa atatcccaag tctttaaata tagcggtgct aagttttatc
     8461 agctaacaca atccagaaag tgctgaaatg aattcagaca cttagaagta acacaagggt
     8521 tcctgttaaa ttatacacgt gtatcactgc ctgatttgaa accccacttt tcctttttaa
     8581 tccagcacaa tatcaaactg tgattctata gctcgtcttt ttaacgtcta caaataaccc
     8641 aaaatctttt ttgttttatg gaaaactttt ctttttaaca ctaactgcaa agtgcttagc
     8701 aaaaggttcc ttctggataa cagcattatt aattattatt atttattatt attattaatt
     8761 attcctcctt caaattgttg gaagacttgc ccctccaaac aggcatttcc caaagacagt
     8821 tttcagaaac ttcacatttc acctaacgaa agctgttcat acgttagtct gcattaggtc
     8881 tctgccaatg tttcccaggt tcacggcccc cgaggggtga tggccatctg tagatgatag
     8941 aaaccacccc atgcggacct gtgaatagca tcagtgtggt tcactttggg taactgggta
     9001 ctcacgtgta tatacttaga tctgcatcat tcaaacctcc tctctgctac tctgcacgca
     9061 cttccagctc ttacgctatt ttaaagttca ctgggttttg gtgatcacca acagaagtgt
     9121 aaacgacgat tgctttcatg agcaggcgtg atttgtttta tggctgttta agttacaaac
     9181 ttgttctcat attgtaggtg aatcaaaagc ctttctgttt ttaaaaggtc actgtaactc
     9241 aagattaaaa tttctcgcac aactttatta gtgttcactt ctgaagctaa taagacaacg
     9301 gagttttcta tgttactctc actgtaacat cgactaagtg actttcaata aaagatttct
     9361 gttattttga
//
