LOCUS       NM_001160228            6286 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus ADAM metallopeptidase domain 19 (Adam19), mRNA.
ACCESSION   NM_001160228 XM_001069002 XM_220328
VERSION     NM_001160228.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6286)
  AUTHORS   Ramdas,V., McBride,M., Denby,L. and Baker,A.H.
  TITLE     Canonical transforming growth factor-beta signaling regulates
            disintegrin metalloprotease expression in experimental renal
            fibrosis via miR-29
  JOURNAL   Am J Pathol 183 (6), 1885-1896 (2013)
   PUBMED   24103556
  REMARK    GeneRIF: TGF-beta stimulation of renal cells results in a
            significant up-regulation of Adams 10, 17, 12, and 19
REFERENCE   2  (bases 1 to 6286)
  AUTHORS   Zhao,M., Qiu,W., Li,Y., Sang,Q.A. and Wang,Y.
  TITLE     Dynamic change of Adamalysin 19 (ADAM19) in human placentas and its
            effects on cell invasion and adhesion in human trophoblastic cells
  JOURNAL   Sci China C Life Sci 52 (8), 710-718 (2009)
   PUBMED   19727588
REFERENCE   3  (bases 1 to 6286)
  AUTHORS   Blobel,C.P.
  TITLE     ADAMs: key components in EGFR signalling and development
  JOURNAL   Nat Rev Mol Cell Biol 6 (1), 32-43 (2005)
   PUBMED   15688065
  REMARK    Review article
REFERENCE   4  (bases 1 to 6286)
  AUTHORS   Kurohara,K., Komatsu,K., Kurisaki,T., Masuda,A., Irie,N., Asano,M.,
            Sudo,K., Nabeshima,Y., Iwakura,Y. and Sehara-Fujisawa,A.
  TITLE     Essential roles of Meltrin beta (ADAM19) in heart development
  JOURNAL   Dev Biol 267 (1), 14-28 (2004)
   PUBMED   14975714
REFERENCE   5  (bases 1 to 6286)
  AUTHORS   Zhou,H.M., Weskamp,G., Chesneau,V., Sahin,U., Vortkamp,A.,
            Horiuchi,K., Chiusaroli,R., Hahn,R., Wilkes,D., Fisher,P.,
            Baron,R., Manova,K., Basson,C.T., Hempstead,B. and Blobel,C.P.
  TITLE     Essential role for ADAM19 in cardiovascular morphogenesis
  JOURNAL   Mol Cell Biol 24 (1), 96-104 (2004)
   PUBMED   14673146
REFERENCE   6  (bases 1 to 6286)
  AUTHORS   Abram,C.L., Seals,D.F., Pass,I., Salinsky,D., Maurer,L., Roth,T.M.
            and Courtneidge,S.A.
  TITLE     The adaptor protein fish associates with members of the ADAMs
            family and localizes to podosomes of Src-transformed cells
  JOURNAL   J Biol Chem 278 (19), 16844-16851 (2003)
   PUBMED   12615925
REFERENCE   7  (bases 1 to 6286)
  AUTHORS   Shirakabe,K., Wakatsuki,S., Kurisaki,T. and Fujisawa-Sehara,A.
  TITLE     Roles of Meltrin beta /ADAM19 in the processing of neuregulin
  JOURNAL   J Biol Chem 276 (12), 9352-9358 (2001)
   PUBMED   11116142
REFERENCE   8  (bases 1 to 6286)
  AUTHORS   Wei,P., Zhao,Y.G., Zhuang,L., Ruben,S. and Sang,Q.X.
  TITLE     Expression and enzymatic activity of human disintegrin and
            metalloproteinase ADAM19/meltrin beta
  JOURNAL   Biochem Biophys Res Commun 280 (3), 744-755 (2001)
   PUBMED   11162584
REFERENCE   9  (bases 1 to 6286)
  AUTHORS   Kurohara,K., Matsuda,Y., Nagabukuro,A., Tsuji,A., Amagasa,T. and
            Fujisawa-Sehara,A.
  TITLE     Meltrin beta (ADAM19) gene: cloning, mapping, and analysis of the
            regulatory region
  JOURNAL   Biochem Biophys Res Commun 270 (2), 522-527 (2000)
   PUBMED   10753657
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before May 17, 2009 this sequence version replaced
            XM_220328.4, XM_001069002.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1372667.1,
                                           SRR26643292.39904.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               JAXUCZ010000010.1  30992761-30992948
            189-274             JAXUCZ010000010.1  30997087-30997172
            275-345             JAXUCZ010000010.1  31001420-31001490
            346-424             JAXUCZ010000010.1  31031326-31031404
            425-501             JAXUCZ010000010.1  31037595-31037671
            502-694             JAXUCZ010000010.1  31049775-31049967
            695-760             JAXUCZ010000010.1  31050584-31050649
            761-832             JAXUCZ010000010.1  31055142-31055213
            833-999             JAXUCZ010000010.1  31058120-31058286
            1000-1084           JAXUCZ010000010.1  31059985-31060069
            1085-1224           JAXUCZ010000010.1  31061943-31062082
            1225-1402           JAXUCZ010000010.1  31064000-31064177
            1403-1492           JAXUCZ010000010.1  31065566-31065655
            1493-1688           JAXUCZ010000010.1  31068506-31068701
            1689-1797           JAXUCZ010000010.1  31070866-31070974
            1798-2011           JAXUCZ010000010.1  31072359-31072572
            2012-2089           JAXUCZ010000010.1  31073219-31073296
            2090-2198           JAXUCZ010000010.1  31073405-31073513
            2199-2337           JAXUCZ010000010.1  31074635-31074773
            2338-2422           JAXUCZ010000010.1  31075504-31075588
            2423-2647           JAXUCZ010000010.1  31075834-31076058
            2648-2800           JAXUCZ010000010.1  31080082-31080234
            2801-6286           JAXUCZ010000010.1  31080970-31084455
FEATURES             Location/Qualifiers
     source          1..6286
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q21"
     gene            1..6286
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /note="ADAM metallopeptidase domain 19"
                     /db_xref="GeneID:303068"
                     /db_xref="RGD:1585017"
     exon            1..188
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..2854
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /note="a disintegrin and metalloproteinase domain 19
                     (meltrin beta); SRY-box containing gene 30; a disintegrin
                     and metallopeptidase domain 19 (meltrin beta); disintegrin
                     and metalloproteinase domain-containing protein 19"
                     /codon_start=1
                     /product="disintegrin and metalloproteinase
                     domain-containing protein 19 precursor"
                     /protein_id="NP_001153700.1"
                     /db_xref="GeneID:303068"
                     /db_xref="RGD:1585017"
                     /translation="MPGRAGVARFCLLALALQLQWPLAACEPEWTTRGSKEDSPPLQH
                     ELIIPQWRTSESPRGGKHPLTAELRVMAEGRELILDLEKNEHLFAPAYTETCYTASGN
                     PQTTTLKSEDHCFYHGTVRKVDESSVTLSTCRGIRGLIIVRSNLSYIIEPVPNSDNQH
                     RIYRSEHLKLPPGNCGFEHSRPTSKDWTLQFTHQTKKQPRRMKREDLHSMKYVELYLV
                     ADYAEFQKNRHDQDATKHKLMEIANYVDKFYRSLSIRIALVGLEVWTHGDKCEVSENP
                     YSTLWSFLSWRRKLLTQKSHDNAQLITGRSFQGTTIGLAPLMAMCSVYQSGGVSMDHS
                     ENAIGVASTVAHEIGHNFGMSHDSAHCCSTSAADGGCIMAAATGHPFPKVFSSCNRKE
                     LDRYLQSGGGMCLSNMPDTRTLYGGRRCGNGYLEDGEECDCGEEDECKNPCCNASNCT
                     LKEGAECAHGSCCHQCKLVAPGTQCREQVRQCDLPEFCTGKSPHCPTNYYQMDGTPCE
                     GGQAYCYNGMCLTYQEQCQQLWGPGARPALDLCFERVNAAGDTYGNCGKGLNGKYRKC
                     SPRDAKCGKIQCQSTQARPLESNAVSIDTTITLNGRRIHCRGTHVYRGPEEEEGEGDM
                     LDPGLVMTGTKCGHNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNKNCHCFPGWAP
                     PFCNTPGDGGSIDSGPLPPKSAGPVIAGVFSALFVLAVLVLLCHCYRQSHKLGKPSAL
                     PFKLRQQFSCPFRVSQNGGTGHANPTFKLQTPQGKRKVTNTPETLRKPSHPPPRPPPD
                     YLRVESHPAPLPAHLNRAAGSSPEAGAQIERKESARRPPPSRPMPPAPNCLLSQDFSR
                     PRPPQKALPANPVPGQRTVPRPGGTSLFHPPTTGPQPPRPPAVSVPKLPEYRSQRIGG
                     ITSSKI"
     exon            189..274
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            275..345
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            346..424
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            425..501
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            502..694
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            695..760
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            761..832
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            833..999
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1084
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1224
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1402
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..1492
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1688
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            1689..1797
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            1798..2011
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2089
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..2198
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            2199..2337
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            2338..2422
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            2423..2647
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            2648..2800
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
     exon            2801..6286
                     /gene="Adam19"
                     /gene_synonym="Sox30"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgtttgcttg aaaaccgccg ccgccgctag gccgggggca ggcaatggca ggggatgtgt
       61 gattgcggac agtgagaggg ccattgctat catgcccggg cgcgcgggcg tcgcccggtt
      121 ctgcttgctg gctctcgctc tgcagctaca gtggccgctg gcggcatgcg aaccggaatg
      181 gaccacaaga ggaagcaaag aagacagccc tccactacaa catgaactca taatacctca
      241 gtggaggact tcagaaagcc ccaggggagg aaagcatcca ctcacggcag agctcagggt
      301 catggctgaa gggcgagagc tgatcctgga cctggagaag aacgagcacc tttttgctcc
      361 agcctacaca gagacctgct acaccgcaag tggcaatcct cagaccacca cgctgaaatc
      421 tgaggatcac tgcttttacc acgggactgt gaggaaagtg gatgagtcca gcgtcactct
      481 cagcacctgc cggggaatta gaggactgat tatagtgaga agtaacctca gctacatcat
      541 cgagcccgtc cctaacagcg acaaccaaca ccgtatttac agatccgaac atctcaagct
      601 gcccccgggg aactgtgggt tcgagcactc caggcccacc tctaaggact ggacccttca
      661 gtttacacat cagaccaaaa agcaacctcg cagaatgaaa cgggaagatt tacactctat
      721 gaagtacgtg gagctttatc tggtggctga ttacgcagag tttcagaaga accggcatga
      781 ccaggatgcc accaaacaca agctcatgga gattgccaac tatgttgata agttttaccg
      841 ctccctgagc atccggattg cgcttgtcgg cttggaggtg tggacacacg gggataagtg
      901 tgaagtctca gagaatccgt actctaccct ctggtccttt ctcagttgga ggcgcaagct
      961 gctcacccag aagagccatg acaatgccca gctaatcacg ggcaggtcct tccaaggcac
     1021 caccattggc ctggcccccc tcatggccat gtgttctgtg taccagtccg gaggagttag
     1081 catggaccac tccgagaatg ccatcggtgt agcctccacc gtggcccacg agattggcca
     1141 caactttggc atgagccatg attctgcaca ctgctgttct accagcgcag ccgatggtgg
     1201 gtgcatcatg gctgctgcta cggggcaccc tttccccaaa gtgttcagtt cgtgcaacag
     1261 gaaggagctg gacaggtatc tgcagtcagg aggtgggatg tgtctctcca acatgccaga
     1321 tacgaggact ctgtatggag gccggaggtg tggcaatggg tacctggaag acggtgaaga
     1381 atgtgactgc ggagaagagg acgaatgtaa gaacccttgc tgcaatgcct ccaactgcac
     1441 tctgaaggaa ggggccgagt gtgcccatgg ctcctgctgc caccagtgta agctggtggc
     1501 tcctggaacc cagtgtcgtg agcaggtgcg gcagtgtgat ctccccgagt tctgcacggg
     1561 caagtccccc cactgcccca ccaactatta ccagatggat ggcaccccct gcgagggtgg
     1621 ccaggcctac tgctacaatg gcatgtgcct cacttatcag gagcagtgcc agcagctgtg
     1681 gggacctgga gccaggcctg ctcttgatct ttgcttcgag agggtgaatg ctgctggtga
     1741 cacctatggt aactgcggca aaggcttgaa tggcaaatac aggaagtgca gccccaggga
     1801 tgccaagtgt gggaagatcc agtgtcagag cacccaggcc aggcccctgg aatccaacgc
     1861 agtatctatt gacaccacca ttaccttgaa cgggaggcgg atccactgtc ggggcaccca
     1921 tgtctaccgg ggtcctgagg aggaagaagg ggagggtgac atgctggacc cagggctggt
     1981 gatgaccggg accaagtgtg gccacaacca tatttgcttc gaggggcaat gcaggaacac
     2041 ctccttcttt gagacggaag gctgtgggaa aaagtgcaat ggtcatgggg tctgcaacaa
     2101 caacaagaac tgtcattgct tccctggctg ggctccacct ttctgtaaca ccccaggaga
     2161 tggcggcagc attgacagtg ggcctttgcc ccctaagagt gcgggtcctg tgattgctgg
     2221 ggtgttttct gccctcttcg tgttggcagt cctggtgcta ttgtgtcatt gctacagaca
     2281 gagccacaaa ctgggcaagc cctcagctct cccttttaag ctgcggcaac agttcagttg
     2341 tcccttcagg gtgtctcaga atggtggaac tggccacgcc aacccaactt tcaagttgca
     2401 gacaccccag ggcaagcgaa aggtgactaa cacccctgaa actctccgga agccctccca
     2461 ccctcctccc cggccccctc cggactacct acgagttgaa tcccatcctg caccactgcc
     2521 agcacatctg aacagggctg ctgggagctc accagaagct ggagctcaga tagaaagaaa
     2581 ggaatcagcc agaagacctc ccccaagccg gcccatgccc cctgcaccga actgcctact
     2641 gtcccaggat ttctccaggc ctcgaccacc tcagaaggca ctcccagcga atcctgtgcc
     2701 gggccaaagg actgttccca ggccaggagg cacctccctg tttcatcccc ctactactgg
     2761 tcctcagcct cccaggcctc cagcagtgtc tgttccaaag cttcctgagt accgatcaca
     2821 gaggattgga gggataacca gctccaagat ctagacgtgt ctagaagttt cttgtttcgc
     2881 ttgaagactc cggatgccat ggaaggtcca gaaggaagaa gcctgcttgg ccaccctgaa
     2941 gcttctgcag ccttctggaa cccacctcat ccccagaatc tcccttcttg ccctagtgcc
     3001 tcctgcttcc tctgagaccc agagggtctc atagccgatg gcttctaagt gttgtcctgt
     3061 gcaatataca gtccgggtag gaaagggaaa catgtggagg aggtttgggg aagattctcc
     3121 ctcagcccgc tagccaagag ctaccaacaa tgttcaggga agtcttgagc tggggtcctc
     3181 ctgtgccgag cttggagaag gtatccatct gggtcctctg ctggcaggta cacacaggag
     3241 cttcagtgat tggcctccca ggctgggcct tactgtctct tagcttttat ggcccgagga
     3301 agctgcatcc ctgccccaag gcttggtcaa ggtgcctgtt cccggctatg tggctgcatg
     3361 tgacaagcca tgctccctca ccccccgcca ttcttcacat tcccactccc atatttacat
     3421 gggtcactct gactcagaca ggtactattt gtaagtagtg tagacagcag gggggagcgg
     3481 tcagcctgtg tcccctctga gccgtgatgc caaaggttgc taaggacttt tagaatcccc
     3541 agccgtacat cccagtgttc catgtgtccc cttctcctcc tctttcagca tccctagcct
     3601 atggtgcttt ggtggtggac cactgcagtc ctgacttgct ggtgactata tgctagtgac
     3661 ctccaaatca ggatcctgcc tcatggggta gccactggac tttctgcact ggatcgcaag
     3721 agcattgagc cgagtgggcg tgtgtgtgtg tgtgtgtgtg tgtgacagag acagtgagag
     3781 agagacaggc aggcagacag acagacagac agctctgcgt gtacttgtat tttatggcct
     3841 caaacaggat aaggggcctc cttccttatt cctgacctat atctaagtaa ggttctccag
     3901 gacagccaca gttatactga ggggggactg acatgtttgg aatcctggct attagtaacg
     3961 tctatgcagg ggcaccagcc cctccctggt ggtcagctct gaggtgagat tgttgactat
     4021 gaacagatca cagttgacag tcacagttaa ctctcttcaa ccaagcactt ccatcagttc
     4081 tctcctggtt actgctccta tgtgattgtc ttggaagatg ctgggaggtg ggaatgggac
     4141 tggcatggac ctcctcttgc ttggtgctct gcctcctaga acagttttca cacatttgcc
     4201 aggcctggcc tcgaagaggc catcttccac ccccaaaaaa ggtgctaata gcactccaga
     4261 gggctctcta ggggccttcc tgccaaccgt ggcgagcggt tgttagctct tggaaccctc
     4321 cagaggaaga ggcaagcttt tgactcccca ttaccacccc gaggcctcct tctatctcct
     4381 cacagagaca agtgagagat acagcataca tggctggcgg gtagaaagat ctcaggaaaa
     4441 catctctttt cttttcaggg taactgtgcc gttcacactc tctgagtgtg atccaaaatc
     4501 ttacttaagg ccttggtcca tctcctgtgt cagtgtctca tttctgtgct ttaccagatg
     4561 cccagtaact acagcttggg ccctagagac agaggccacc ccgattctca ccacaaagtt
     4621 agaaaccctc cactttcttt cccttgagcc acatcagaaa aaagacccat ttccttgctc
     4681 attggcaatc acttcggctt ttttctcttt cgttactctc gtaccacctc catcccataa
     4741 aactatactg tgaaccgtaa gagggcagga ttttttaact cggtagaaat gctggcagct
     4801 actctccaaa agccagggag gctgtcacag gtaggaatcc cttcccgtct gcattgtgaa
     4861 gggtcccgta caggtgtacc taggcttcaa agacagggct cgtcccaaag gattgtcact
     4921 taggagatga aagaatatta ccacatgggg aggagggggc gcttgcaaca gaacactttg
     4981 gtctacctac accaagtctg tgagggcatg caagactgaa aaggcctttt cttatgcata
     5041 gaaagtgagc aagactagaa ataactgtcc aaggcgtctc tgttcctggc cactgaagag
     5101 agatgtcaga aggcgttgga ataggtcgaa gccaaggctc cagtgggctg agggaaggtt
     5161 tggagctgga tttcgtggtg tacaccttta gtcccaggag aggtaggtga atctcttgag
     5221 tatgagggta gcctggtcta aaaaggaagt tccaggacag ccagggccac accgagaaaa
     5281 aaaaaatcaa ctctacaaaa acaagtaaaa attaagacag gatctcaagt atcctaggtt
     5341 ggccttcaag tcacttcaaa agtagagaaa gaaaactgag ggtgaccttt gaactcctga
     5401 gtgctggctt cttcccgcgt gctcagactg ccagtgtgtg ctaccatgct tcatgtggtc
     5461 ctgggttcaa acacagacct tcatgtgtct ataggcaacc accctaccaa ctgatctaca
     5521 tccctcagcc acagcccctg ccaaccttag aactgcaaag ccatttctga cctgtaaacc
     5581 tcagctccca atctctgtaa gatgtgtagc cttggctaat cccttccaca ttgcaactcc
     5641 ctgcttgctt cctattcctt ctagccttgg tgacttccac ccgtaagaga aaagcccctt
     5701 ttaacccctg ctccaaaaca ttgtagatgt tagggtctgg atgctctctg caattcaaca
     5761 gtcccttctg ttgcagtagc tccctgccac gctccagtaa tccttcagtg tctcctctgg
     5821 gctcaatgaa tttgcttatt tgacaaagtg ggcgtgagac ttgtattctt aaaattggag
     5881 gttagtcatt ttgtcaaatg cgtgtcatga cagacccaaa aggactccac acacaagcca
     5941 gggacaccaa ctggaaaggt gcccctctcc cagggaagcc tgctagggag aggttctgta
     6001 gaacccaagc ccagcagccc aaagtcatgc acccagtgtc ctcttgtatg actgtgtata
     6061 tgtctgtctg ggatccaggg caaatgtgaa ttttcttttg attcgggaga ttgttcacag
     6121 gaaatagtcc tctcctctca tgtcctccta ttgattgttt acaatatttg tacatctatg
     6181 caaaatactt gaatgggccg tggtgccttg ttttgttttt tcttgttttt tgtttttttt
     6241 tttcctcctt gtttgtattt aattaaaaca aattgtcatt aggaaa
//
