LOCUS       NM_001014047            3064 bp    mRNA    linear   ROD 15-DEC-2024
DEFINITION  Rattus norvegicus N6-Methyl-AMP deaminase (Mapda), mRNA.
ACCESSION   NM_001014047 XM_017591735 XM_230500
VERSION     NM_001014047.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3064)
  AUTHORS   Murakami,E., Bao,H., Mosley,R.T., Du,J., Sofia,M.J. and Furman,P.A.
  TITLE     Adenosine deaminase-like protein 1 (ADAL1): characterization and
            substrate specificity in the hydrolysis of N(6)- or
            O(6)-substituted purine or 2-aminopurine nucleoside monophosphates
  JOURNAL   J Med Chem 54 (16), 5902-5914 (2011)
   PUBMED   21755941
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On or before Mar 1, 2022 this sequence version replaced
            XM_017591735.2, NM_001014047.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.2090402.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-450               JAXUCZ010000003.1  128555604-128556053
            451-661             JAXUCZ010000003.1  128557217-128557427
            662-792             JAXUCZ010000003.1  128557652-128557782
            793-853             JAXUCZ010000003.1  128558348-128558408
            854-941             JAXUCZ010000003.1  128562530-128562617
            942-1023            JAXUCZ010000003.1  128564056-128564137
            1024-1150           JAXUCZ010000003.1  128566303-128566429
            1151-1231           JAXUCZ010000003.1  128567401-128567481
            1232-1370           JAXUCZ010000003.1  128568797-128568935
            1371-1471           JAXUCZ010000003.1  128571131-128571231
            1472-3064           JAXUCZ010000003.1  128571712-128573304
FEATURES             Location/Qualifiers
     source          1..3064
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     gene            1..3064
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /note="N6-Methyl-AMP deaminase"
                     /db_xref="GeneID:311352"
                     /db_xref="RGD:1359517"
     exon            1..450
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
     exon            451..661
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
     CDS             602..1684
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /EC_number="3.5.4.4"
                     /note="adenosine deaminase-like"
                     /codon_start=1
                     /product="adenosine deaminase-like protein"
                     /protein_id="NP_001014069.2"
                     /db_xref="GeneID:311352"
                     /db_xref="RGD:1359517"
                     /translation="MEARQQWARKTDFYMQLPKVELHAHLNGSISSSTMRKLIAKKPH
                     LQVHGHMTMIDKGKKRTLEECFQMFQVIHQLTTSAEDILMVTKDVIKEFADDGVKYLE
                     LRSTPRGENATGMTRKTYVESVLEGIKQCKQENLDIDVRYLMAIDRKGGPTVAKETVK
                     LAKEFFLSAEDTVLGLDLSGDPTIGQAKDFLEPLLEAKKAGLKLALHLAEIPNKEKET
                     QMLLDLLPDRIGHGTFLNTPEAGSVDQVNFVRQHRIPLELCLTSNIKSQTVPSYDQHH
                     FGFWYSVAHPSVICTDDKGVFATSLSQEYQLAAETFNLTPSQVWDLSYESINYIFASN
                     NTRSELRKRWTHLKQKVLGCNEVNYF"
     exon            662..792
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
     exon            793..853
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
     exon            854..941
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
     exon            942..1023
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1150
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1231
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
     exon            1232..1370
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
     exon            1371..1471
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
     exon            1472..3064
                     /gene="Mapda"
                     /gene_synonym="Adal"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcacgtaa tagccgcggt ggataagcgg cgtgcgccgc acgatccctg ggaccagcag
       61 cggcgcgaag gcatcgctca cgtacccttg tgcggctagc gatcgcttgc tgagggagct
      121 gctgtcattg gtgctctgaa ccgtccccgt ccggcgctgg cggcttcgcg ggcccatgac
      181 cagaaggcgc tccgcaattc tccacacaga acgttcaccg aactccagct ctcccgcttc
      241 cgggtgcgtc acttccgggc aaatcgctgt cagccaaaaa ccgcgagaga ctttttgaca
      301 ttttttttcc ttccaaatta cattttcccg cgaacacgcc ctctgcttac ttaacagcta
      361 gcgtttgggg agttcaggtt accactttgt acaggcattt tctataggga acaaccttgt
      421 ataggtcctc gtatttgaga acattttcag gtgaaagtga tccgaaagct acacatagag
      481 caagtcttct taaaatatgg caatctgaag aaagtccagc acctcagaaa ttatgatttt
      541 gtaagttgta ttgtccaagc caagaataaa atccaagaga aactttcctt ctactaaagt
      601 gatggaggcc agacagcagt gggcacggaa gacagacttt tacatgcaat tgccaaaagt
      661 ggagcttcac gcccacttga atggctccat tagttccagt accatgagga aattaatagc
      721 caagaagcca catcttcaag ttcatggtca catgacaatg attgacaagg gaaagaaaag
      781 gactttagaa gaatgtttcc agatgttcca agttattcat cagcttacta ctagtgctga
      841 ggacatcctg atggtcacaa aagatgtcat taaggagttt gcagatgatg gtgtcaagta
      901 cctggagctg aggagcactc ccagaggaga aaatgctact ggcatgacta ggaagactta
      961 cgtggaatcc gtactggaag gcataaaaca gtgcaaacaa gaaaacttag acattgacgt
     1021 taggtatttg atggcaattg acagaaaagg tggcccgaca gtagccaagg agactgtcaa
     1081 acttgctaaa gagttcttcc tctctgctga ggatacagtt cttggccttg acctcagtgg
     1141 agatccaact atcggacaag caaaagactt cttggagcct cttttagaag ctaaaaaagc
     1201 aggcctgaag ttggcgttgc atcttgcaga gattccaaat aaggaaaaag aaacacagat
     1261 gttgctggat ctgcttcctg acagaattgg gcatggaaca ttcctcaaca cccccgaggc
     1321 agggtcagtg gatcaggtga acttcgtgag gcaacaccgg atacctcttg aactttgttt
     1381 gacctcaaac atcaaaagcc agacagttcc ttcttatgac cagcatcact ttggattctg
     1441 gtatagcgtt gctcatcctt ctgtgatctg taccgatgat aaaggtgttt ttgcaacaag
     1501 cctttctcaa gaatatcaac tggcagcaga aacatttaat ctgaccccat cgcaggtgtg
     1561 ggatctgtct tatgaatcca tcaactacat cttcgcttct aacaacacca gatctgaact
     1621 gagaaaaagg tggactcacc tgaaacagaa agtgttaggc tgtaacgagg tgaactactt
     1681 ttgattatac gtcgtaacca aggtcttcct gccctgtgta ccccactcag ttactgccca
     1741 cttgaaatta cttcaagttc agtagccaag tatatatggg tctaactcca gcaccttcat
     1801 atggtaagtg cttagtatcc cagactaaga gccttgaggt cttgcatggc agtgcctcca
     1861 tgctgtttgc tgggaggttg ttaaaccttc attccctagt gactctgttt tttcacatag
     1921 cactctcttg ccattggtga ccataaacct tctgagaagt tgaaactctg actttaggga
     1981 aacctccgtt ttgttatgtt taatcagatt ccttccactt ccctttatcc tttcggagtt
     2041 tttttttttt aggtcacagt gcacacctgc actgtttgtg tgggtgccta gttgtgaggc
     2101 gactgcagta acaaagctag aatctggctt tgcccttctc ataatatctt tagaaatata
     2161 taaagggggt tggagtaatc actctagttt aggaaaagaa tgactgactt aagtaagaaa
     2221 gacacatagc cagagcttct ggtttaaaat cagcttctat ttggcttccc ttgggaagct
     2281 accaggacct ccacagtgct aggactccct taaaagatct ttgtagtaat ggtagcattg
     2341 tggcatctag ggttcttaga tcaccaataa tcccatgccc agatgatggc ccacacgcac
     2401 agatttacat aaacacacgt ataccatggc ctcatcagcc aaagataggt gacggctaag
     2461 attggttctg aatgcaaaga aaaagacttt aacagataac aaatgtcttg gatatttttt
     2521 ttccacaagc tagagtcatt tgggaagagg gaccctcaac tgagaaaatg ctcccacaag
     2581 atcggcttaa tcagtgcttg agcagttagt gggctcatgc cacagagggt gatgccccct
     2641 cagggatgtg gttttggtgg aaagtgaagg aaatggaaca tgaggagcaa gctataggca
     2701 gcactcctct atggctcagc ttcagttcct gcctcagctt cccaggatga gggactacaa
     2761 attatgaggc aataaacccc ttcctcctca agttactttt ggtgatggtg tttatcacag
     2821 cattaaaaac actaaactaa taacgtatgc ttgaattatt ctccttctta gaatgtatgg
     2881 tttccctgat ctcagagaag aaacctggtg gcacccttaa ttcaataaag gttgagattt
     2941 ttgtttctgc cttttagggt acatgataaa ggaaagtact taattttcaa agttcttagt
     3001 tattgtttta taaccttata tttctaacta tatccactta cacaataaaa tctgtaaaat
     3061 gtaa
//
