LOCUS       NM_001169145            1156 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus acylphosphatase 2 (Acyp2), mRNA.
ACCESSION   NM_001169145 XM_001055227 XM_001059049 XM_001059111
VERSION     NM_001169145.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1156)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1156)
  AUTHORS   Parrini,C., Taddei,N., Ramazzotti,M., Degl'Innocenti,D.,
            Ramponi,G., Dobson,C.M. and Chiti,F.
  TITLE     Glycine residues appear to be evolutionarily conserved for their
            ability to inhibit aggregation
  JOURNAL   Structure 13 (8), 1143-1151 (2005)
   PUBMED   16084386
REFERENCE   3  (bases 1 to 1156)
  AUTHORS   Chiti,F., Calamai,M., Taddei,N., Stefani,M., Ramponi,G. and
            Dobson,C.M.
  TITLE     Studies of the aggregation of mutant proteins in vitro provide
            insights into the genetics of amyloid diseases
  JOURNAL   Proc Natl Acad Sci U S A 99 Suppl 4 (Suppl 4), 16419-16426 (2002)
   PUBMED   12374855
REFERENCE   4  (bases 1 to 1156)
  AUTHORS   Berti,A., Tremori,E., Pazzagli,L., Degl'Innocenti,D., Camici,G.,
            Cappugi,G., Manao,G. and Ramponi,G.
  TITLE     Rat muscle acylphosphatase: purification, amino sequence, and
            immunological characterization
  JOURNAL   J Protein Chem 10 (1), 91-102 (1991)
   PUBMED   1647162
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB613181.1, CO404339.1 and AW521357.1.
            
            On or before Dec 18, 2009 this sequence version replaced
            XM_001059111.1, XM_001059049.1, XM_001055227.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ224926.1, FM111314.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760396
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-547               CB613181.1         11-557
            548-832             CO404339.1         379-663
            833-1156            AW521357.1         1-324               c
FEATURES             Location/Qualifiers
     source          1..1156
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q22"
     gene            1..1156
                     /gene="Acyp2"
                     /note="acylphosphatase 2"
                     /db_xref="GeneID:364224"
                     /db_xref="RGD:1595836"
     exon            1..272
                     /gene="Acyp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             140..514
                     /gene="Acyp2"
                     /EC_number="3.6.1.7"
                     /note="acylphosphate phosphohydrolase 2; acylphosphatase,
                     muscle type isozyme; acylphosphatase-2-like;
                     acylphosphatase 2, muscle type"
                     /codon_start=1
                     /product="acylphosphatase-2"
                     /protein_id="NP_001162616.1"
                     /db_xref="GeneID:364224"
                     /db_xref="RGD:1595836"
                     /translation="MSLLRLASVALSAPHTPLRLLARGLAAMAEPLKSVDYEVFGTVQ
                     GVCFRMYTEGEAKKRGLVGWVKNTSKGTVTGQVQGPEEKVNSMKSWLSKVGSPSSRID
                     RADFSNEKTISKLEYSNFSIRY"
     exon            273..289
                     /gene="Acyp2"
                     /inference="alignment:Splign:2.1.0"
     exon            290..399
                     /gene="Acyp2"
                     /inference="alignment:Splign:2.1.0"
     exon            400..1140
                     /gene="Acyp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcagagagg gagctccctg cttgggagct ggagcgcccg gtgtcctgcc gtcctcacta
       61 cggactgcgg actgcggtgt cctgtggtct tgcgtgaccc ggcgcgtacc cgtcctgcca
      121 ggcgtcggtc ccagagccca tgagcctcct tcgcctggcg tctgtcgcac tctccgcacc
      181 acacaccccg ctacggctgc tcgcgagagg gctggccgcc atggcggagc cgcttaagtc
      241 tgtggactac gaagtgttcg ggacagtgca aggtgtttgc ttcagaatgt atacagaagg
      301 agaagctaag aaaagaggtc tggttggctg ggtgaagaat acaagcaaag gcacagtgac
      361 aggtcaagtt caaggccctg aagaaaaggt caattccatg aagtcctggc tgagcaaggt
      421 tgggagtcct agttctcgca tcgaccgggc cgacttttct aacgaaaaaa caatctctaa
      481 actggaatac tctaatttta gtattcgata ttaataaaag aaagagatca attgcaatgc
      541 ttatattata gaagataaaa catattctta ggtttataat agtaggcgag taggattaaa
      601 aatggaaagt ttttgttctg gaattataca ttactgaaat ttctgaaact gaaaaacttt
      661 actcacctat gttttagcaa gcagaaacta aatattataa aataaaatgt cattataaat
      721 tatctagtat gaacattcaa gttaaatatt gtcttatgga gtcattcatt tcagaaaata
      781 ttacagtatt tgttacttta tattacatta tatatgttat ttggctagac ataaaataaa
      841 attaactatg taaaattacc tatggatact gttgcctaat tgacttttaa agtcctctga
      901 ataataactt actattaagg ttgagcgatt agccttaaaa attgttaaaa taaattcgtg
      961 tgatgatcac cataaccaga aagtactagc aatagacagt tagtgtgtaa acttctcctt
     1021 aaactcaagc ctggttcagt acaaagttgg acttacttac tatccttgac ttaattgttc
     1081 tgtagtttga agagtgttgt tgtaaaaata taaaaaataa aagagtattg gtgtctttta
     1141 aaaaaaaaaa aaaaaa
//
