LOCUS       NM_001013961            1393 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus actin-related protein T1 (Actrt1), mRNA.
ACCESSION   NM_001013961 XM_229114
VERSION     NM_001013961.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1393)
  AUTHORS   Bal,E., Park,H.S., Belaid-Choucair,Z., Kayserili,H., Naville,M.,
            Madrange,M., Chiticariu,E., Hadj-Rabia,S., Cagnard,N., Kuonen,F.,
            Bachmann,D., Huber,M., Le Gall,C., Cote,F., Hanein,S., Rosti,R.O.,
            Aslanger,A.D., Waisfisz,Q., Bodemer,C., Hermine,O.,
            Morice-Picard,F., Labeille,B., Caux,F., Mazereeuw-Hautier,J.,
            Philip,N., Levy,N., Taieb,A., Avril,M.F., Headon,D.J., Gyapay,G.,
            Magnaldo,T., Fraitag,S., Crollius,H.R., Vabres,P., Hohl,D.,
            Munnich,A. and Smahi,A.
  TITLE     Mutations in ACTRT1 and its enhancer RNA elements lead to aberrant
            activation of Hedgehog signaling in inherited and sporadic basal
            cell carcinomas
  JOURNAL   Nat Med 23 (10), 1226-1233 (2017)
   PUBMED   28869610
  REMARK    Erratum:[Nat Med. 2025 Feb 6. doi: 10.1038/s41591-025-03531-y..
            PMID: 39915680]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083679.1.
            
            On Apr 20, 2005 this sequence version replaced XM_229114.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC083679.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1393
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq35"
     gene            1..1393
                     /gene="Actrt1"
                     /note="actin-related protein T1"
                     /db_xref="GeneID:302796"
                     /db_xref="RGD:1359559"
     exon            1..1354
                     /gene="Actrt1"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..1248
                     /gene="Actrt1"
                     /codon_start=1
                     /product="actin-related protein T1"
                     /protein_id="NP_001013983.1"
                     /db_xref="GeneID:302796"
                     /db_xref="RGD:1359559"
                     /translation="MLNTARLDNPAVIFDNGSGLCKVGISGEIVPRHVINSVVGHPKF
                     NIPSARSNRKRYFVGEEAQCMYDGLYLHYPIERGLVTRWDDMEKLWKDLFEWELGVKP
                     NEQPVFMTEPSLNPRETREKTTEIMFEKFNVPALYLCNHAVGALCASACITGLVLDSG
                     DGVTCTVPIYEGYSLPRAITKLYVAGRDITEHLTRLLLAKGYTFPCILNKAVVDDIKE
                     KLCTVSWGSKDSEKCYQRSLSEYKLPDGNTIQMSDHLCQVPEVLFTPEHLGIHDLGIS
                     KMVCNSIMKCDTDIQENLFAEIVLSGGTTLFPGLQDRLLKELEVLAFEGTPIKITASP
                     DRCYSAWIGGSVMTSLTTFKQMWVTAEDFKEYGAFVVQRKCF"
ORIGIN      
        1 ttcatgggct aaggacctgc tcctctggtg gactggtaac aactcaggta cctttcattc
       61 ttctgagtgg tccaactaaa cattctattg ctggcatata aaagatcaaa tccagacatg
      121 cttaatacgg ctagattaga taatcctgcc gtgatatttg acaatggttc tggactctgt
      181 aaagttggaa tttcaggaga gattgtaccc cgtcatgtca tcaactctgt tgttggccac
      241 ccaaaattca acatcccatc tgcaagatcc aatcggaaaa ggtactttgt gggagaagaa
      301 gcccagtgca tgtatgacgg tttataccta cactatccta ttgagcgtgg actggtaact
      361 agatgggatg acatggaaaa actgtggaag gacctttttg agtgggagtt aggagtgaaa
      421 cccaatgaac agccagtttt catgactgaa ccttccttga acccacgaga aacccgagag
      481 aagaccacag aaataatgtt tgagaaattt aatgtacctg ccttgtacct ttgcaaccat
      541 gcagtaggag ccctgtgtgc ttctgcctgt atcacgggcc tggtactgga cagtggagat
      601 ggggttactt gcactgttcc aatctacgaa ggctactctc ttcctcgtgc tatcaccaag
      661 ctatacgtag cagggagaga tatcacagaa cacctcaccc gactccttct tgctaaaggc
      721 tacaccttcc cctgcatcct caacaaagca gtggtagatg atattaaaga gaagttatgt
      781 actgtctcct ggggctctaa agattcagaa aagtgctatc agcggtccct aagtgaatac
      841 aagctgccag atgggaatac catccagatg agtgaccacc tctgccaggt gcctgaagtt
      901 ctttttacac ctgaacatct aggtattcat gatttaggaa tctcaaaaat ggtctgcaac
      961 agcatcatga aatgtgacac tgatatccag gagaacctgt ttgccgagat tgtgctttct
     1021 ggagggacca cactgtttcc tgggcttcag gatagactcc tgaaagaact agaagttctg
     1081 gcttttgagg gaacccctat caagatcaca gcttctccag acagatgcta ttcagcttgg
     1141 attggtggat ctgtcatgac atccttgaca acatttaagc agatgtgggt cactgctgaa
     1201 gatttcaagg agtacggggc atttgtggtg caaagaaaat gcttttaagg accaccaaac
     1261 tcaggggact cctataaata ccagatgaca ggagtattgg tgggggtaat catgccatca
     1321 ttccttggca tttaataaaa taaaattaaa tctgaaaaaa aaaaaaaaaa aaaaaaaaaa
     1381 aaaaaaaaaa aaa
//
