LOCUS       NM_001014162            2432 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus acyl-CoA synthetase medium-chain family member 5
            (Acsm5), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001014162 XM_341916
VERSION     NM_001014162.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2432)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001014162.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078915.1, SRR26360194.824139.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-228               JAXUCZ010000001.1  183302509-183302736
            229-448             JAXUCZ010000001.1  183304665-183304884
            449-659             JAXUCZ010000001.1  183308009-183308219
            660-867             JAXUCZ010000001.1  183310419-183310626
            868-1011            JAXUCZ010000001.1  183312493-183312636
            1012-1165           JAXUCZ010000001.1  183313013-183313166
            1166-1245           JAXUCZ010000001.1  183314941-183315020
            1246-1369           JAXUCZ010000001.1  183318738-183318861
            1370-1450           JAXUCZ010000001.1  183319591-183319671
            1451-1552           JAXUCZ010000001.1  183319792-183319893
            1553-1680           JAXUCZ010000001.1  183321873-183322000
            1681-1780           JAXUCZ010000001.1  183322263-183322362
            1781-1900           JAXUCZ010000001.1  183324144-183324263
            1901-2432           JAXUCZ010000001.1  183325137-183325668
FEATURES             Location/Qualifiers
     source          1..2432
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q35"
     gene            1..2432
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /note="acyl-CoA synthetase medium-chain family member 5"
                     /db_xref="GeneID:361637"
                     /db_xref="RGD:1309578"
     exon            1..228
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            229..448
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     CDS             248..1984
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /EC_number="6.2.1.2"
                     /note="acyl-coenzyme A synthetase ACSM5, mitochondrial"
                     /codon_start=1
                     /product="acyl-coenzyme A synthetase ACSM5, mitochondrial
                     precursor"
                     /protein_id="NP_001014184.3"
                     /db_xref="GeneID:361637"
                     /db_xref="RGD:1309578"
                     /translation="MRLWLRGLVYQARRSSWGVFRIHTQPPPPPIPEVVATWEAISLG
                     KRPVPEYFNFAHDVLDVWSQLEKTGHRPPNPAFWWVNGSGTEVKWTFEELGKQSRKAA
                     NILEGACGLKPGDRLMLVLPRLPEWWLTIVACMRTGVVMIPGISQLTQKDLKYRLQAA
                     RVKSIITSDALAPHVDAISADCPSLQSRLLVSDTSRPGWINFRELLRVASPEHNCLRT
                     RSGDSMAIYFTSGTTGTPKMVEHSQCSYGLGFVASGRRLMALTESDIFWNTTDTGWVK
                     AAWTLFSAWANGACVFVHELPQVDAQTILNTLCRFPITTICCVPTLFRLLVQEDLTRY
                     KFQCLRHCLAGGEALNSDVRDKWKNQTGLEIHEGYGQSETVLICGNFRGSTIKSGSMG
                     KASPPYDVQIVDEEGNVLPPGKEGNIAIRIKPTRPFCLFNCYLDNPEKTAASEQGDFY
                     ITGDRAHMDEDGYFWFVGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPI
                     RGEVVKAFIVLSPAYVSHDPEALTRELQEHVKTVTAPYKYPRKVAFISELPKTVSGKI
                     LRSKLRNQEWGR"
     exon            449..659
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            660..867
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            868..1011
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1165
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1245
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            1246..1369
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1450
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1552
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            1553..1680
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..1780
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            1781..1900
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
     exon            1901..2432
                     /gene="Acsm5"
                     /gene_synonym="Aa2-174; Cc1-38; RGD1309578"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaaaaccct ggcgtgaagc cgctttcaca gacttagtgt ccctaccctc tgaaagttga
       61 agctcctgac tcctaatccg gctctccata ggctgtgctt ggggctaaag ctccctgtct
      121 gaatcctgcc tccatcagct tctggggaaa tctcaggagc tttgtggtct gccttgctgc
      181 cgaagtggaa cacagatgcc ttgtgtgcac ctcagattct aaaacaaggc agaaggtgac
      241 agaagacatg aggttatggc tgagaggtct ggtctaccag gctcggagga gttcctgggg
      301 agtcttcagg attcacacac agccaccacc tccccctatc cctgaggttg tagctacctg
      361 ggaagccatc agcctaggga agcggccagt gccggagtac ttcaactttg cccacgatgt
      421 gctagatgtg tggagtcagc tggaaaagac agggcaccgc cccccaaatc ctgcattctg
      481 gtgggtgaat ggctcaggaa cagaagtcaa gtggacattt gaggaactgg gaaagcagtc
      541 caggaaggca gccaacatct tagagggagc atgtggcctg aaacctggag acagattaat
      601 gctggtgctt ccgagactcc cagaatggtg gctgaccatc gtggcttgta tgcgaacagg
      661 tgtggtcatg atcccaggca tttcccagct gacacagaag gatctcaagt accggctaca
      721 ggctgccagg gtcaaatcca tcatcaccag tgatgcccta gctcctcacg tggatgccat
      781 cagtgctgac tgcccctccc ttcaaagcag gcttctggtg tctgatacca gtcgtccagg
      841 ctggatcaat ttccgggaac tcctgagagt ggcatctcca gaacacaact gcctgagaac
      901 cagaagtgga gattcaatgg ccatctactt caccagtgga accacgggga cccccaagat
      961 ggtggaacat tcccagtgca gctatggact gggttttgtg gccagtggaa ggaggttgat
     1021 ggccttgact gaatccgaca tattctggaa cacaactgac actggttggg tgaaagcagc
     1081 ctggactctc ttctctgcct gggccaatgg cgcttgcgtt tttgtgcatg agctgcccca
     1141 agttgatgcc caaactattc taaatactct ctgcaggttc ccaataacca ccatttgctg
     1201 tgtcccaacc ctcttccggc tgcttgtaca agaggatctg acaaggtaca agttccagtg
     1261 cctcagacac tgtttggccg gtggagaagc cctcaactct gacgtgaggg acaagtggaa
     1321 gaaccagaca ggcctggaga tccatgaagg ctacggacaa tcagaaacag tcctcatctg
     1381 tggcaatttt agaggctcaa cgatcaagtc tggatctatg gggaaagcaa gcccacctta
     1441 cgatgtgcag attgtagacg aggagggtaa tgtcctgcct ccaggaaaag agggaaatat
     1501 tgccatccgc atcaaaccta ctagaccctt ctgtctcttc aactgctatc tggacaatcc
     1561 tgagaagaca gcagcatcag agcaaggaga cttttacatc actggggacc gagcacatat
     1621 ggacgaggac ggctactttt ggttcgtggg gagaaatgat gatgtaatca actcttcaag
     1681 ctaccggatt gggcctgtgg aagtagagag tgcactggct gagcatccgg ctgtcctgga
     1741 gtctgctgtg gtcagcagcc cagaccccat ccggggagag gtggtaaagg cgtttatagt
     1801 cctttctcca gcctatgtgt ctcatgaccc agaagccctg accagggaac tccaggagca
     1861 tgtgaagaca gtgactgctc catacaagta ccccaggaag gtggctttta tttcggaact
     1921 gccaaagacg gtttctggaa agatcctaag gagtaaattg agaaaccaag agtgggggag
     1981 atgaggcgca acccaagaaa gatgctgtga ctctctgaag gttctcaagg agaaggaagt
     2041 ggggctggct agctactcct tggaggagaa taggcatcaa agatggtcag cttccaaatg
     2101 ggcattttgg aatgatgctg gcaaatgcaa gaacatctct agtccagagc tcacagacac
     2161 tgcccagtcc agcaaattca ccaaagctta acttccatct ctggagatct tcagcattct
     2221 gttgtccctg ggaaggacaa atcagcacaa ccttaatcca tggtcttgtt atgccagtgg
     2281 aaatgtaaaa tgtgaccctt tggatgaagt catttggtaa cagtatctgg gtcataacat
     2341 tgaccatact cttccattta gaaatcacac ttttgggact cactataaaa gaaaagactc
     2401 aaaatacagt aaacatttgg tatgcaaaga ta
//
