LOCUS       NM_181695               2056 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus acyl-CoA synthetase medium-chain family member 4
            (Acsm4), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_181695
VERSION     NM_181695.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 2056)
  AUTHORS   Watkins,P.A., Maiguel,D., Jia,Z. and Pevsner,J.
  TITLE     Evidence for 26 distinct acyl-coenzyme A synthetase genes in the
            human genome
  JOURNAL   J Lipid Res 48 (12), 2736-2750 (2007)
   PUBMED   17762044
REFERENCE   3  (bases 1 to 2056)
  AUTHORS   Oka,Y., Kobayakawa,K., Nishizumi,H., Miyamichi,K., Hirose,S.,
            Tsuboi,A. and Sakano,H.
  TITLE     O-MACS, a novel member of the medium-chain acyl-CoA synthetase
            family, specifically expressed in the olfactory epithelium in a
            zone-specific manner
  JOURNAL   Eur J Biochem 270 (9), 1995-2004 (2003)
   PUBMED   12709059
  REMARK    GeneRIF: Results indicate that olfactory medium-chain acyl-CoA
            synthetase (O-MACS) may play an important role in processing
            odorants in a zone-specific manner, or in zonal patterning of the
            olfactory epithelium during development.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_181695.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB096688.1, SRR22582416.477561.1
                                           [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-80                JAXUCZ010000001.1  183485259-183485338
            81-322              JAXUCZ010000001.1  183488692-183488933
            323-533             JAXUCZ010000001.1  183489722-183489932
            534-741             JAXUCZ010000001.1  183493427-183493634
            742-885             JAXUCZ010000001.1  183498234-183498377
            886-1042            JAXUCZ010000001.1  183498685-183498841
            1043-1122           JAXUCZ010000001.1  183500950-183501029
            1123-1246           JAXUCZ010000001.1  183503321-183503444
            1247-1327           JAXUCZ010000001.1  183504919-183504999
            1328-1429           JAXUCZ010000001.1  183505118-183505219
            1430-1557           JAXUCZ010000001.1  183505722-183505849
            1558-1657           JAXUCZ010000001.1  183505942-183506041
            1658-1777           JAXUCZ010000001.1  183508069-183508188
            1778-2056           JAXUCZ010000001.1  183509434-183509712
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q35"
     gene            1..2056
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /note="acyl-CoA synthetase medium-chain family member 4"
                     /db_xref="GeneID:353317"
                     /db_xref="RGD:727928"
     exon            1..80
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            81..322
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..1864
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /EC_number="6.2.1.2"
                     /note="acyl-coenzyme A synthetase ACSM4, mitochondrial;
                     O-MACS; olfactory specific medium-chain acyl CoA
                     synthetase"
                     /codon_start=1
                     /product="acyl-coenzyme A synthetase ACSM4, mitochondrial
                     precursor"
                     /protein_id="NP_859046.1"
                     /db_xref="GeneID:353317"
                     /db_xref="RGD:727928"
                     /translation="MKVLLRCQRLRFIWLAKPAGRHFHRDPQLWAPLTLDDFEAINRC
                     EKPLPKNFNFAADVLDQWSLKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAA
                     NVLTKPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQLTRKDILYRLQAS
                     KAKCIVASEEVAPAVDSIASECPNLKTKLLVSPHRWDGWLSFQELLQSASEEHNCVQT
                     GSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTSSDIMWNMSDTGWIK
                     AAIGSVFSTWLRGACVFVHRMAQFNTDTFLDTLTSYPITTLCSAPTVYRMLVQQDLKR
                     YQFKRLRHCLTGGEPLNPEVLEQWKAQTGLELYEGYGQTEVGIICANRKGEEIKPGSM
                     GKGVVPYDVQIIDEHGNILPSGKEGEIALRLGSDRPFCFFSEYVDNPEKTDATIRRNF
                     YITGDRGVMDDDGYLWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDP
                     IRGEVVKAFIVLAAPFKSSNREKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGK
                     IKRNVLRDQEWGRA"
     exon            323..533
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            534..741
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            742..885
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            886..1042
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1122
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1246
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1327
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1429
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1557
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..1657
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1777
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
     exon            1778..2056
                     /gene="Acsm4"
                     /gene_synonym="Omacs"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggaaggaag caactttgtg gcagaaacag cctttgagaa ggagcgggag gcctttctag
       61 atccgcagga cggcttgctg acattgccca cttggtatca gaaaacagtt tttcaggaat
      121 catgaaggtt ctcctccgct gtcagagact tagattcatc tggcttgcca agcctgctgg
      181 ccggcacttc cacagagacc cccagctctg ggcacctctg acattggatg actttgaagc
      241 catcaaccgc tgtgagaagc cattacccaa gaactttaac tttgctgcgg atgttctcga
      301 ccagtggtct ctaaaggaga agtctggaga gaggccagcc aacccagccc tgtggtgggt
      361 gaatggcaaa ggagatgagg tgaagtggag tttccaagaa ctgggctcct tgtcccgaaa
      421 ggctgccaac gtgctcacca agccctgtgg cctgcagagg ggagaccggg tagctgtgat
      481 tctgccccgc atccctgaat ggtggctcat caatgtggct tgcatgagaa cagggcttgt
      541 cttcatgcct ggaacaatcc aactgaccag aaaagacatc ctctaccggc tgcaagcatc
      601 caaggccaag tgcattgtgg ccagtgagga agtggcccct gcagtggact ccattgcatc
      661 agagtgtccc aacttgaaga ctaagcttct ggtgtctcca caccgctggg acgggtggct
      721 cagctttcag gaattacttc aatcagcctc tgaagagcac aattgtgtgc agacaggaag
      781 tcaagagcca atggccattt acttcaccag tgggaccaca ggctccccca agatggctca
      841 gcactcacag agcagccttg gcattgggta tgccctttgt ggaaggtact ggctggactt
      901 gacatcatca gatatcatgt ggaacatgtc agacactggc tggatcaagg ctgccattgg
      961 tagtgtgttt tccacgtggc ttcgaggtgc ctgtgttttt gtgcaccgga tggcccagtt
     1021 caacactgat accttcctag atacgcttac ctcatatcct atcacgaccc tgtgcagtgc
     1081 tcctaccgtg taccggatgc ttgtacaaca ggaccttaag aggtatcaat tcaagaggct
     1141 gcggcactgc ctgacaggag gggagccact caaccccgag gtgctggaac agtggaaggc
     1201 acaaactggg ctggagctat acgagggcta cggacagact gaagtgggaa taatttgcgc
     1261 caatcgcaaa ggagaagaaa ttaaaccagg ctccatggga aagggagtag tgccctacga
     1321 tgtgcagatt atagatgaac atggaaatat cctaccatcg ggcaaggaag gggagattgc
     1381 ccttaggctg gggtctgatc ggcccttctg cttcttctct gaatatgtgg acaatccaga
     1441 gaagactgat gccacaataa gaagaaattt ttacatcact ggagacagag gagtgatgga
     1501 cgatgatgga tacctttggt ttgtcggcag agctgatgat gtcattatat cctccgggta
     1561 ccgaattggg ccgtttgaag tagagagtgc actgatagag cacccagcag tagttgagtc
     1621 agctgttgtc agcagtccag atccaatccg aggagaggtg gtgaaagcgt ttattgtatt
     1681 agctgcaccc ttcaagtcct ccaaccgtga gaagttaact gctgaacttc aggatcatgt
     1741 gaaaaactca acagcacctt acaagtaccc aagaaaggtg gaatttgttc aagaactccc
     1801 caagacaatc actgggaaaa tcaaacgcaa cgtgttaaga gaccaggagt ggggacgggc
     1861 ataactggat aagaaccgag atgggaggag cgatgtggtt ggtttcagta cttgcttcct
     1921 gatagttcag tgactatact ctttcctatt tcactcttaa aacgctttgt ctttcctgtt
     1981 tcactcttta aatgctttaa catgtttttt cctatttgaa aatagttgta tctaggaaaa
     2041 caataaacaa gcaaaa
//
