LOCUS       NM_001401526            1993 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus acid phosphatase 4 (Acp4), transcript variant 1,
            mRNA.
ACCESSION   NM_001401526 XM_006229051
VERSION     NM_001401526.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1993)
  AUTHORS   Seymen,F., Kim,Y.J., Lee,Y.J., Kang,J., Kim,T.H., Choi,H.,
            Koruyucu,M., Kasimoglu,Y., Tuna,E.B., Gencay,K., Shin,T.J.,
            Hyun,H.K., Kim,Y.J., Lee,S.H., Lee,Z.H., Zhang,H., Hu,J.C.,
            Simmer,J.P., Cho,E.S. and Kim,J.W.
  TITLE     Recessive Mutations in ACPT, Encoding Testicular Acid Phosphatase,
            Cause Hypoplastic Amelogenesis Imperfecta
  JOURNAL   Am J Hum Genet 99 (5), 1199-1205 (2016)
   PUBMED   27843125
REFERENCE   2  (bases 1 to 1993)
  AUTHORS   Fleisig,H., El-Din El-Husseini,A. and Vincent,S.R.
  TITLE     Regulation of ErbB4 phosphorylation and cleavage by a novel
            histidine acid phosphatase
  JOURNAL   Neuroscience 127 (1), 91-100 (2004)
   PUBMED   15219672
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 15, 2022 this sequence version replaced XM_006229051.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.2839.1,
                                           SRR26360181.53155.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-232               JAXUCZ010000001.1  103880925-103881156 c
            233-388             JAXUCZ010000001.1  103880498-103880653 c
            389-493             JAXUCZ010000001.1  103877967-103878071 c
            494-580             JAXUCZ010000001.1  103877802-103877888 c
            581-727             JAXUCZ010000001.1  103876901-103877047 c
            728-826             JAXUCZ010000001.1  103876235-103876333 c
            827-922             JAXUCZ010000001.1  103876063-103876158 c
            923-1055            JAXUCZ010000001.1  103875310-103875442 c
            1056-1138           JAXUCZ010000001.1  103875144-103875226 c
            1139-1266           JAXUCZ010000001.1  103874647-103874774 c
            1267-1445           JAXUCZ010000001.1  103874380-103874558 c
            1446-1993           JAXUCZ010000001.1  103872922-103873469 c
FEATURES             Location/Qualifiers
     source          1..1993
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1993
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /note="acid phosphatase 4"
                     /db_xref="GeneID:308569"
                     /db_xref="RGD:1308270"
     exon            1..232
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     exon            233..388
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     CDS             323..1855
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /EC_number="3.1.3.2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     testicular acid phosphatase; acid phosphatase, testicular"
                     /codon_start=1
                     /product="testicular acid phosphatase isoform 1"
                     /protein_id="NP_001388455.1"
                     /db_xref="GeneID:308569"
                     /db_xref="RGD:1308270"
                     /translation="MHHWRSPVLCSVLRLETQGTYMVFRHGDRAPLASYPTDPHKEAA
                     STLWPRGLGQLTKEGIRQQLELGRFLRRRYKAFLSPEYRREEVYIRSTDFDRTLESAQ
                     ANLAGLFPEAAPGSPEADWKPIPVHTVPVSEDKLLRFPMRSCPRYHELLRESTEAADY
                     QEALEGWTDFLTRLGNFTGLSLVGEPLRRAWKVLDTLICQRAHGLALPSWASPDVLRT
                     LSQISALDIRAHVGPPRAAEKAQLTGGILLDAILSNFSRAQRLGLPLKMVMYSAHDST
                     LLALQGALGLYDGNTPPYAACMAFEFRGSSREPEEEDGENVTVSLIYRNDTSRPPLPL
                     RVPGCPAPCPLGRFQQLTAPARPPAHGAPCHGSYEPASPPDRWSILWKQAKGGQVRLC
                     LTCPGPSSSPRFYPRRDRIKQHTPQRAMIQPFNRNSRRQKFQGCPPHPSTKSRSTLAR
                     GHLCSQGDQTQLEGASRGKGMVKRKWGQGPQSKVFTKGGSPPHKKVSHKLKIKYKVKM
                     LH"
     exon            389..493
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     exon            494..580
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     exon            581..727
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     exon            728..826
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     exon            827..922
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     exon            923..1055
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1138
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1266
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1445
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1993
                     /gene="Acp4"
                     /gene_synonym="Acpt"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgggtagaag agacattgga actggggatt gggaggaagg ggatgtaggt gtgtagtgtc
       61 acccatggga cctaaatcca gcatcaggac ttatgagatt ggagagtaca gacctggatc
      121 tccacactgg gtcccatttt cttccctaga gtgtgctggg gagccagggg agagttgtga
      181 gctgggaagg gacagatagc ctctggtatc ttgaggcagg agaatgactg aggttcttag
      241 aggtgcagcc gagaggggag atacacgtgt gtgtggaact gccttcatcc cccactaatt
      301 gctaccggct gtgcacagag ggatgcacca ctggaggagc ccagttcttt gcagtgtcct
      361 caggctggag actcagggga catacatggt gttccgacat ggcgaccggg ccccactggc
      421 ctcctacccc acagatccac acaaggaagc tgcctccacc ttgtggcccc gaggtttggg
      481 ccaactgact aaggagggca tccgccagca gctggaactg ggccgatttc tgaggaggcg
      541 ttacaaggcc ttcctgagcc ctgagtacag gcgcgaagag gtgtacatcc gcagcacaga
      601 ctttgaccgg acattggaga gtgcacaggc caacctggct gggctcttcc ccgaggctgc
      661 ccctggaagt cctgaggctg actggaagcc cattccagtg cacacagtgc ctgtgtctga
      721 ggacaagttg ctgaggttcc ccatgcgcag ctgccctcga taccatgagc tgttgcggga
      781 gtccacagag gcagctgact accaggaggc cctggagggc tggacagact tcttgacccg
      841 cctgggcaac ttcactgggc tgtccctggt tggagagcca ctccgcagag catggaaagt
      901 tctggatacc ttgatctgtc agcgcgccca tggtcttgct cttccctcct gggcctcccc
      961 agatgtcttg aggactctgt cacagatttc cgctctggat atcagggcac atgtgggccc
     1021 accccgagca gcagaaaagg cccagctgac aggggggatt ctgctggatg ccatcctcag
     1081 caacttctct cgggctcagc gcctggggct gcccctcaag atggtcatgt actcagctca
     1141 tgacagcacc ctgctggccc tccagggggc tctgggcctc tacgatggga acaccccacc
     1201 ttatgctgcc tgcatggcct ttgaattccg ggggagctcc agggaacctg aggaggaaga
     1261 tggagagaat gtcactgtct ctctcatcta ccgcaatgac acctctcgcc cacccctgcc
     1321 actcagggtc cctgggtgcc cagctccctg tccacttggg cgcttccagc agctgactgc
     1381 tccagcccgg cctccagctc acggggcccc ctgccatggt tcttatgagc ctgccagccc
     1441 cccagaccgc tggagtatcc tctggaaaca ggccaaaggt gggcaagtgc gcctgtgcct
     1501 cacctgccct ggacccagct catcacccag attctaccca cgccgggacc gaatcaaaca
     1561 gcacactcca cagagggcaa tgatccagcc atttaatagg aactcacgaa ggcaaaagtt
     1621 ccagggctgc ccacctcacc cctccactaa atccagatct acattggcca gaggccatct
     1681 gtgcagccag ggagaccaga cccagctgga aggtgcttca agagggaagg gtatggttaa
     1741 aagaaaatgg ggacagggtc cccaaagcaa agtctttaca aaagggggtt ctcctcccca
     1801 caaaaaagtg tcacataagc tcaaaataaa atataaagta aaaatgctgc attagaaaag
     1861 tttgcaatgt taagccttta caataggaga ctggccctca agtgtcaaac atccagtata
     1921 agtccatgga agtgcagcct atacctaaaa tctatgtaag tgttgcattg aaaaagtaaa
     1981 aaattcaaga tgg
//
