LOCUS       NM_001109440            2582 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus acyl-CoA thioesterase 4 (Acot4), mRNA.
ACCESSION   NM_001109440 XM_001059814 XM_001059880
VERSION     NM_001109440.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2582)
  AUTHORS   Ghosh,D. and Berg,J.M.
  TITLE     A proteome-wide perspective on peroxisome targeting signal
            1(PTS1)-Pex5p affinities
  JOURNAL   J Am Chem Soc 132 (11), 3973-3979 (2010)
   PUBMED   20178365
REFERENCE   2  (bases 1 to 2582)
  AUTHORS   Hunt,M.C., Rautanen,A., Westin,M.A., Svensson,L.T. and Alexson,S.E.
  TITLE     Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene
            clusters shows that convergent, functional evolution results in a
            reduced number of human peroxisomal ACOTs
  JOURNAL   FASEB J 20 (11), 1855-1864 (2006)
   PUBMED   16940157
REFERENCE   3  (bases 1 to 2582)
  AUTHORS   Westin,M.A., Hunt,M.C. and Alexson,S.E.
  TITLE     The identification of a succinyl-CoA thioesterase suggests a novel
            pathway for succinate production in peroxisomes
  JOURNAL   J Biol Chem 280 (46), 38125-38132 (2005)
   PUBMED   16141203
REFERENCE   4  (bases 1 to 2582)
  AUTHORS   Kikuchi,M., Hatano,N., Yokota,S., Shimozawa,N., Imanaka,T. and
            Taniguchi,H.
  TITLE     Proteomic analysis of rat liver peroxisome: presence of
            peroxisome-specific isozyme of Lon protease
  JOURNAL   J Biol Chem 279 (1), 421-428 (2004)
   PUBMED   14561759
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001109440.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643286.20446.1,
                                           SRR26643287.16516.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-590               JAXUCZ010000006.1  109399854-109400443
            591-793             JAXUCZ010000006.1  109402029-109402231
            794-2582            JAXUCZ010000006.1  109403350-109405138
FEATURES             Location/Qualifiers
     source          1..2582
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q31"
     gene            1..2582
                     /gene="Acot4"
                     /note="acyl-CoA thioesterase 4"
                     /db_xref="GeneID:681337"
                     /db_xref="RGD:1596753"
     exon            1..590
                     /gene="Acot4"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..1399
                     /gene="Acot4"
                     /EC_number="3.1.2.2"
                     /codon_start=1
                     /product="acyl-coenzyme A thioesterase 4"
                     /protein_id="NP_001102910.1"
                     /db_xref="GeneID:681337"
                     /db_xref="RGD:1596753"
                     /translation="MAATLSLEPAGRSCWDEPLSITVRGLAPEQPVTLRAALRDEKGA
                     LFRAHARYHADSHGMLDLARAPALGGSFAGLEPMGLLWAMEPERPFWRLIKRDVQTPF
                     VVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGQGPFPGI
                     IDVYGVGGGLLEYRASLLAGHGFATLALAFYGFEDLPKEFNVIEVDYFEEAVCYMLQH
                     PKVKGPDIGLLGLSLGADVCLIMASFLKNVSATVSINGSAFSGNRYIHYKQTMIPPLG
                     HDLRRTKVAFSGILDIVDIRNDAVGGCENPSMIPIEKAKGPILFVAGQDDHCWRSELY
                     TQIASERLQAHGKERPQIISYPGTGHYIEPPYFPMCPASLHKIVNKAVVWGGEVRAHS
                     KAQIDAWKQILSFFGKHLDSTHNRASCRL"
     exon            591..793
                     /gene="Acot4"
                     /inference="alignment:Splign:2.1.0"
     exon            794..2582
                     /gene="Acot4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctgtgccc aaattgctga cagacttcgg ggcctctctt gtctgggtcc tagagaccca
       61 ccaggtcggc tccacagcag gccaggctct gctccgaact ccgcgtggtg ctctcgtaag
      121 ttttcagctc cccatggcgg cgacgctgag cctggagccc gccggccgca gctgctggga
      181 cgagccgctg agcatcacgg tgcgcggcct ggccccggag cagcccgtca cgctgcgcgc
      241 cgccctgcgc gacgagaagg gcgcgctctt ccgagcccac gcgcgctacc acgccgactc
      301 ccacggaatg ctggacctgg cgcgcgctcc cgcgctgggc ggcagcttcg cggggctcga
      361 gcccatgggg ctgctctggg ctatggaacc cgaacggcct ttctggcgtc tgatcaagcg
      421 cgacgtgcag acgcccttcg tggtggagct ggaggtgctg gacggacacg agcccgacgg
      481 cggacagcgg cttgcacggg cggtgcacga gcgtcacttc atggctcccg gggtgcggcg
      541 cgtgcccgtg cgcgagggcc gggtgcgcgc cacgctcttt ctgcctccag gacaaggacc
      601 ctttccaggg atcatcgatg tctatggtgt tggagggggc ctattggaat accgagccag
      661 ccttctggct ggtcatggct ttgccacatt ggctctggct ttttatggct ttgaagatct
      721 ccctaaagag ttcaatgtca tagaagtgga ctactttgaa gaagcagtgt gctacatgct
      781 ccaacacccg aaggtaaaag gcccagacat tggacttctg ggtctttctc taggagctga
      841 tgtttgcctg atcatggctt ccttcttgaa gaatgtttca gccacagttt ccatcaatgg
      901 ctctgcattc agcggaaaca gatacataca ctacaagcag actatgattc caccattggg
      961 ccatgacctg aggagaacga aggtggcttt ctcaggcatt ctggacattg tggatatacg
     1021 gaatgacgct gtaggaggct gtgagaaccc cagcatgata ccaatagaga aggccaaggg
     1081 gcccatcctc tttgttgctg gtcaggatga ccattgctgg aggagtgagt tatacactca
     1141 gatagcctcg gaacggttac aggctcacgg aaaggagagg cctcagataa tctcttaccc
     1201 tgggactggg cattacatcg agccacctta cttccccatg tgcccagctt ccctgcacaa
     1261 aatagtgaac aaagctgtgg tctggggagg ggaggtcagg gctcactcaa aagcccagat
     1321 agatgcatgg aagcaaattc tatccttctt tggcaaacac ctggacagta ctcacaacag
     1381 agcctcctgc agattgtagt gcgtttgcct gtaacagaca tggcagattc aaggtcaaat
     1441 tttaatgtcc agtgactatg tgaatcagtt ttctgctgga tgacatgaaa ttcatgttcg
     1501 gggcattaat ggttattaat caatggttac cctaccatca acatgtgctt gccacagatt
     1561 cagctatatg agatacaatg agtaaagttt aaaaaacagc gatccctgtt aaaacgtctc
     1621 atttcttcta agctcagcat ttctgtggta gttgcagctg ttttgttcca tttattattg
     1681 ttttgttttt ttcttttggg gacaggacct cagctttggc tggcctggaa cttgccatgt
     1741 aaaggaagct ggccttgaac tcacagagac tatcctgctt ttgcctcctg agtgccagga
     1801 ttaaaggctc ccaccaccat gcatgcattc attttcctac ttagtcagtg ctttgactca
     1861 tggctcacct ttaaagaccg tgactggggc tgcctcgttt catgtcaact ctactgacac
     1921 aagctggcgt catctgaaag gagggagcct gatgtgtgtg cacatccacc tgaatataca
     1981 tgtgtgtacc ttccacacgc aggcacccat gcacacatgc agccacatgt gtacacacac
     2041 atgcacacat atacatattt gcacaacaca cacacacgca caccaagaca acaagacaac
     2101 aaggaaaaaa tgacaatttt gccatctcaa tggggtagat agagccttta aataattttc
     2161 caaataatat ttctgaaaat gcttctcacc tgtattgatt aaaacagcaa agaaacaaaa
     2221 atctgtggct ttctattcaa gatcacttgg agccttatta ttttttccca ttcaagctaa
     2281 aaggtaaacg ttaagagaga ctccctaaag tttcattttg caagaaatac aattggatta
     2341 gggtctcttt aatcaaccca taaatttcag tgtgtgagtg tgtgtgtgaa tgtgtgtgtg
     2401 agtgtgtgtg tgtcagtgtg tgagtgtgta tgtgaatgtg tgtatgagtg tgtgtgagtg
     2461 tgtgtatgag tgtgtgagtg tgtgtgtgtg agtgtgtatg agtgtgtgtg tgagtgtgtg
     2521 tatgaatgtg tgagtgtgtg tatgagtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
     2581 tg
//
