LOCUS       NM_001108041            1964 bp    mRNA    linear   ROD 17-JUL-2023
DEFINITION  Rattus norvegicus acyl-CoA thioesterase 3 (Acot3), mRNA.
ACCESSION   NM_001108041 XM_001055592 XM_234399
VERSION     NM_001108041.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1964)
  AUTHORS   Hunt MC, Rautanen A, Westin MA, Svensson LT and Alexson SE.
  TITLE     Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene
            clusters shows that convergent, functional evolution results in a
            reduced number of human peroxisomal ACOTs
  JOURNAL   FASEB J 20 (11), 1855-1864 (2006)
   PUBMED   16940157
REFERENCE   2  (bases 1 to 1964)
  AUTHORS   Westin MA, Alexson SE and Hunt MC.
  TITLE     Molecular cloning and characterization of two mouse peroxisome
            proliferator-activated receptor alpha (PPARalpha)-regulated
            peroxisomal acyl-CoA thioesterases
  JOURNAL   J Biol Chem 279 (21), 21841-21848 (2004)
   PUBMED   15007068
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473982.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_234399.4, XM_001055592.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO572510.1, FM055856.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132264, SAMD00132274
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1964
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q31"
     gene            1..1964
                     /gene="Acot3"
                     /gene_synonym="RGD1564089"
                     /note="acyl-CoA thioesterase 3"
                     /db_xref="GeneID:314304"
                     /db_xref="RGD:1564089"
     exon            1..504
                     /gene="Acot3"
                     /gene_synonym="RGD1564089"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..1313
                     /gene="Acot3"
                     /gene_synonym="RGD1564089"
                     /EC_number="3.1.2.2"
                     /codon_start=1
                     /product="acyl-CoA thioesterase 3"
                     /protein_id="NP_001101511.1"
                     /db_xref="GeneID:314304"
                     /db_xref="RGD:1564089"
                     /translation="MHAFTTQNRMAPTVILEPAVGCLCDQPVHITVRGLGPEQPVTLR
                     AALRDEKGALFRAHARYRADAHGVLDLERAPALGGSFTGLEPMGLIWAMEPERPFWRL
                     VKRDVQTPFVVELEVLDGHEPDGGRLLAQAVHERHFMAPGVRRVPVREGRVRATLFLP
                     PGNGSFPGIIDLFGLGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKDVDIIHLEYFE
                     EAVNYLLSHPQVKGSGVGVLGISKGGELGFAMATFLKNITAAVIINGSVANVGGTLQY
                     RDETILPVGMSTKRIKRIKDGLKDIVDALNNPLEGADQKSLIPVERSDTTFLFLVGQD
                     DHNWKSEFYAREASKRLQAHGKEKPQIICYPETGHYIEPPYFPLCKASLHSLVGGPVI
                     WGGEPRAHAMAQVDAWQQLQTFFHKHLGGEKKTIPAKL"
     exon            505..707
                     /gene="Acot3"
                     /gene_synonym="RGD1564089"
                     /inference="alignment:Splign:2.1.0"
     exon            708..1964
                     /gene="Acot3"
                     /gene_synonym="RGD1564089"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccagccaca atctgaagca atgcacgcat ttaccaccca gaaccggatg gcacccacag
       61 tgatcctgga gcccgcggtt ggctgccttt gcgaccagcc ggtgcacatc accgtgcgcg
      121 gcctgggccc cgagcagccc gtcacgctgc gcgcggccct gcgcgacgag aagggcgcgc
      181 tcttccgagc ccacgcgcgc taccgcgccg acgcccatgg agtgctggac ctggagcgcg
      241 cgcccgcgct gggcggcagc ttcaccgggc tcgagcccat ggggctgatc tgggccatgg
      301 aacccgaacg gcctttctgg cgtctggtca agcgcgacgt gcagacgccc ttcgtggtgg
      361 agctggaggt gctggacgga cacgagcccg acggcgggcg gctgctggcg caggcggtgc
      421 acgagcgtca cttcatggct cccggggtgc ggcgcgtgcc ggtgcgcgag ggccgggtgc
      481 gcgccacgct cttcctgccc ccagggaatg gatcctttcc tggaatcata gacctttttg
      541 gacttggagg cggccttctg gagtaccggg cgagtctgct ggctgggaag ggctttgccg
      601 tcatggctct ggcttattac aactacgacg acctccccaa ggacgtggac attatccacc
      661 tggagtactt tgaggaagcg gtgaactacc tgctcagtca ccctcaggta aaaggttcag
      721 gagttggggt gcttggcatt tccaaggggg gtgaacttgg ctttgccatg gccaccttcc
      781 tgaaaaatat cacagctgct gtcattatca atggctctgt agccaacgtc ggtggaacct
      841 tacagtacag ggatgagacc atactcccgg tgggcatgag caccaaacga atcaagagga
      901 tcaaagatgg cctcaaagac attgtggatg ccctgaacaa tcctctggaa ggagctgacc
      961 agaagagctt gatccctgtg gaaaggtctg acacaacctt cctgttcctc gttggtcagg
     1021 atgaccacaa ctggaagagc gagttctatg ccagagaggc ctccaaacgc ttgcaggccc
     1081 atgggaagga gaagccccag atcatctgtt acccagagac aggccactat attgagcctc
     1141 cttatttccc cttgtgtaag gcttccctgc acagcctggt gggcggtcct gtcatctggg
     1201 gaggggagcc cagggctcac gccatggccc aggttgatgc ttggcagcaa ctccagactt
     1261 ttttccacaa acatttgggt ggggaaaaga agacaatccc agcaaaactg tgatttttat
     1321 ttaagtttta ttttacttaa gatctctgat gctactctct cctggggaag cctccactgt
     1381 tttgtgtgtg tgtgtgagtg tgtgtgtgtg tgtgtttctc ttttacatca atgtagtgtc
     1441 ttccttcctc caacattctt ttaaactgca ggcctcactg ataagtcttg gaggggagtg
     1501 attatagaga aacataaggc acggcaaaag ctggtctctt gctgaggccc aggctgccag
     1561 tgcgctgtag cctgagagaa aggccaagtc actgctaaat cctggacttc agggattact
     1621 tgctaaatgg ctggttaaag acaaacagat ggttacctgc tgcttagaca aacatcaaaa
     1681 agaactgggc agatggctaa ccagttaagg gcccacacta ctcctatagg acccaagttc
     1741 agttcccagc accaggacca agcagctatc aattgactac aactccagct ctgagagata
     1801 cagggctctg cattcatctg acctccttgg gcacccatac ccatgtgttc atacacacat
     1861 gtctccgttg cataatttcg gactacacac acacacacgt acacatgccc catacacaca
     1921 cacacacaca cacacacata cacatgaaca aaaacacatg gttt
//
