LOCUS       NM_001106111             743 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus acyl-CoA thioesterase 13 (Acot13), mRNA.
ACCESSION   NM_001106111 XM_001070460 XM_214475
VERSION     NM_001106111.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 743)
  AUTHORS   Kang HW, Ozdemir C, Kawano Y, LeClair KB, Vernochet C, Kahn CR,
            Hagen SJ and Cohen DE.
  TITLE     Thioesterase superfamily member 2/Acyl-CoA thioesterase 13
            (Them2/Acot13) regulates adaptive thermogenesis in mice
  JOURNAL   J Biol Chem 288 (46), 33376-33386 (2013)
   PUBMED   24072708
REFERENCE   2  (bases 1 to 743)
  AUTHORS   de Mateo S, Castillo J, Estanyol JM, Ballesca JL and Oliva R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 743)
  AUTHORS   Cao J, Xu H, Zhao H, Gong W and Dunaway-Mariano D.
  TITLE     The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2)
            substrate recognition and catalysis illuminated by a structure and
            function based analysis
  JOURNAL   Biochemistry 48 (6), 1293-1304 (2009)
   PUBMED   19170545
REFERENCE   4  (bases 1 to 743)
  AUTHORS   Cheng Z, Song F, Shan X, Wei Z, Wang Y, Dunaway-Mariano D and Gong
            W.
  TITLE     Crystal structure of human thioesterase superfamily member 2
  JOURNAL   Biochem Biophys Res Commun 349 (1), 172-177 (2006)
   PUBMED   16934754
REFERENCE   5  (bases 1 to 743)
  AUTHORS   Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
            E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
            Mann M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474064.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_214475.3, XM_001070460.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AW917195.1, FQ217526.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..743
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p11"
     gene            1..743
                     /gene="Acot13"
                     /gene_synonym="Them2"
                     /note="acyl-CoA thioesterase 13"
                     /db_xref="GeneID:291135"
                     /db_xref="RGD:1306513"
     exon            1..313
                     /gene="Acot13"
                     /gene_synonym="Them2"
                     /inference="alignment:Splign:2.1.0"
     CDS             233..655
                     /gene="Acot13"
                     /gene_synonym="Them2"
                     /EC_number="3.1.2.2"
                     /note="thioesterase superfamily member 2"
                     /codon_start=1
                     /product="acyl-coenzyme A thioesterase 13"
                     /protein_id="NP_001099581.1"
                     /db_xref="GeneID:291135"
                     /db_xref="RGD:1306513"
                     /translation="MSNMTQNLREIMKVMFKVPGFDRVLEKVTLVSAAPEKLICEMKV
                     EEQHTNKFGTLHGGLTATLVDSISTMALMCTERGAPGVSIDMNITYMSPAKIGEEIVI
                     TAHILKQGRTLAFASVDLTNKATGKLIAQGRHTKHLGN"
     exon            314..498
                     /gene="Acot13"
                     /gene_synonym="Them2"
                     /inference="alignment:Splign:2.1.0"
     exon            499..743
                     /gene="Acot13"
                     /gene_synonym="Them2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgaggggg gggagaaggc ctaaatgctg cgcgtgcgca ctgaggcgct agagggtgga
       61 ggtaacactt gctcttcaag gtcttaggca accggagcac gcgacctttc tccggagcgc
      121 gacccgaaac cccccaggct tgcagacttg acggtccacg tccttgtact ttcacaaacg
      181 tctcttccaa agttcattct cgcagagccc agactcttgc tttgcgtcca cgatgagcaa
      241 catgacccag aatctacggg aaataatgaa ggttatgttc aaagttcccg gttttgatag
      301 agttttggaa aaggtgacac ttgtctctgc tgctcctgaa aagctaatct gtgaaatgaa
      361 agtggaggag cagcacacta ataagtttgg tactctccac ggcggcttga cggcaaccct
      421 tgtggacagc atatccacca tggctctaat gtgcacagaa agaggggcac ccggagtcag
      481 tattgacatg aacataacgt acatgtcacc tgctaagatc ggagaagaaa tagtgatcac
      541 agcacatatt ctgaagcaag gaagaacgct ggcatttgcc tcagtggatc tgaccaacaa
      601 ggccacagga aaattaatag cacaaggcag acacacaaag catctgggaa actgagaaca
      661 tcgggatgac ctgaagacgc ccaacaatgc cgagtatagt atatttcaat tttctgaaat
      721 aaatgatcaa aaccagaagt agc
//
