LOCUS       NM_078621               1705 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus atypical chemokine receptor 2 (Ackr2), mRNA.
ACCESSION   NM_078621
VERSION     NM_078621.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1705)
  AUTHORS   Borroni,E.M., Cancellieri,C., Vacchini,A., Benureau,Y., Lagane,B.,
            Bachelerie,F., Arenzana-Seisdedos,F., Mizuno,K., Mantovani,A.,
            Bonecchi,R. and Locati,M.
  TITLE     beta-arrestin-dependent activation of the cofilin pathway is
            required for the scavenging activity of the atypical chemokine
            receptor D6
  JOURNAL   Sci Signal 6 (273), ra30.1-ra3011,S1-S3 (2013)
   PUBMED   23633677
  REMARK    Erratum:[Sci Signal. 2013 Aug 13;6(288):er5]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1705)
  AUTHORS   Zlotnik,A. and Yoshie,O.
  TITLE     Chemokines: a new classification system and their role in immunity
  JOURNAL   Immunity 12 (2), 121-127 (2000)
   PUBMED   10714678
  REMARK    Review article
REFERENCE   3  (bases 1 to 1705)
  AUTHORS   Bonini,J.A., Martin,S.K., Dralyuk,F., Roe,M.W., Philipson,L.H. and
            Steiner,D.F.
  TITLE     Cloning, expression, and chromosomal mapping of a novel human
            CC-chemokine receptor (CCR10) that displays high-affinity binding
            for MCP-1 and MCP-3
  JOURNAL   DNA Cell Biol 16 (10), 1249-1256 (1997)
   PUBMED   9364936
REFERENCE   4  (bases 1 to 1705)
  AUTHORS   Bonini,J.A. and Steiner,D.F.
  TITLE     Molecular cloning and expression of a novel rat CC-chemokine
            receptor (rCCR10rR) that binds MCP-1 and MIP-1beta with high
            affinity
  JOURNAL   DNA Cell Biol 16 (9), 1023-1030 (1997)
   PUBMED   9324304
REFERENCE   5  (bases 1 to 1705)
  AUTHORS   Nibbs,R.J., Wylie,S.M., Pragnell,I.B. and Graham,G.J.
  TITLE     Cloning and characterization of a novel murine beta chemokine
            receptor, D6. Comparison to three other related macrophage
            inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5
  JOURNAL   J Biol Chem 272 (19), 12495-12504 (1997)
   PUBMED   9139699
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086449.1.
            
            [WARNING] On Aug 6, 2024 this sequence was replaced by NM_078621.3.
            
            On Nov 22, 2004 this sequence version replaced NM_078621.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC086449.1 [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1705
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1705
                     /gene="Ackr2"
                     /gene_synonym="Ccbp2; D6"
                     /note="atypical chemokine receptor 2"
                     /db_xref="GeneID:140473"
                     /db_xref="RGD:620323"
     exon            1..1687
                     /gene="Ackr2"
                     /gene_synonym="Ccbp2; D6"
                     /inference="alignment:Splign:2.1.0"
     CDS             269..1417
                     /gene="Ackr2"
                     /gene_synonym="Ccbp2; D6"
                     /note="chemokine-binding protein 2; CCR10-related
                     receptor; C-C chemokine receptor D6; chemokine-binding
                     protein D6; CC-chemokine-binding receptor JAB61"
                     /codon_start=1
                     /product="atypical chemokine receptor 2"
                     /protein_id="NP_511176.2"
                     /db_xref="GeneID:140473"
                     /db_xref="RGD:620323"
                     /translation="MPTIASPLPLATTGPENGSSIYDYDYLDDVTVLVCSKDEVLSFG
                     RVFLPVVYSLIFVLGLAGNLLLLVVLLHSVPQRRRMIELYLLNLAVSNLLFVVTMPFW
                     AISVAWHWVFGSFLCKVVSTLYSINFYCGIFFITCMSLDKYLEIVHAQPLHRPKTRFR
                     NLLLIVMVWITALAVSVPEMVFVKVHQTLDGVWHCYADFGGHATIWKLYLRFQMNLLG
                     FLFPLLAMIFFYSRIGCVLVRLRPPGQGRALRTAAALVVVFFLLWFPYNLTLFLHSLL
                     DLHVFGNCEISHRLDYMLQVTESLAFSHCCFTPVLYAFSSHSFRQYLKAVLSVVLRRH
                     QAPGTAHAPPCSHSESSRVTAQEDVVSMNDLGERQADISLNKGEIGNN"
ORIGIN      
        1 tctgtgtctg tgtgtgttta aatgttcgtg tgtgtgagca tgtgcgtgtg gatgtcagag
       61 gacaggctca tgtcagtttc ttctgagcta gtgctggcct gtgagcttct gatgcttcct
      121 tctctgtctc ttccttcagg attgtagctg tgccttctgc ctctagcttt gtgtgggtgc
      181 caaggatgtg tgcgcggcga gcgctttgcc cgctgaacca tctcctcagg ccctcactgc
      241 ggcttttgtt tcctgcagaa ctcgagacat gcccaccatc gcttctcccc tgcctctcgc
      301 caccaccggt cctgagaacg gcagctccat ctacgactat gactacttgg atgacgtgac
      361 tgtcttggtt tgcagcaaag atgaggtcct gtcctttggc agagtctttc tgccggtggt
      421 ctacagcctg atctttgtgc tgggcctggc cggcaacctc cttctcctgg tggtattgct
      481 ccactctgtg cctcaacgac gacggatgat tgagctgtac ctgctgaacc tggctgtctc
      541 caacctcttg tttgtagtga cgatgccctt ctgggccatc tctgtggcct ggcattgggt
      601 tttcggcagt ttcctgtgca aggtggtgag cactctctac tctattaact tttactgtgg
      661 catcttcttc atcacctgca tgagtctgga caaatacctg gagattgtcc acgctcagcc
      721 cctccacaga cccaagaccc ggttcaggaa cctgcttctc attgtcatgg tgtggatcac
      781 agccctggct gtctctgtcc cagaaatggt ctttgtgaag gtccaccaga ccttagatgg
      841 tgtgtggcac tgctatgccg attttggcgg acatgcaacc atttggaagc tgtacctgcg
      901 cttccagatg aacctcctgg ggtttctctt cccactgttg gccatgattt tcttttactc
      961 ccgcatcggt tgtgttctgg tcaggctgag gccaccggga cagggccggg ctctgaggac
     1021 ggctgcggcc ctggtggtag tcttcttcct gctgtggttc ccgtacaacc tcaccttgtt
     1081 cctgcactcg ctgctggatc tgcatgtctt tgggaactgt gagatcagcc accgtctgga
     1141 ctatatgttg caggtgacag agagcctggc cttctcccat tgttgcttca ccccagtcct
     1201 ctatgccttc tccagtcaca gtttccgcca gtaccttaaa gcggttctgt ccgtggtgct
     1261 gagacggcac caggcacctg gcaccgccca cgcccctcca tgtagccatt cggagagcag
     1321 cagggttact gcccaggaag atgtggtcag catgaacgac cttggcgaga ggcaggctga
     1381 catctccctt aacaaggggg agataggaaa taattaatcc ccgggtctgg gaacggtggt
     1441 tctctctgag ggacagcatg gccgtgcttg ctgcttgccc cagtggtttc caaccaccag
     1501 cagtctttgt tcactactgc ctctccctcc ttccacttcc tgatcccata ctcactgatg
     1561 aaccactgca gctcttcact gatctccgct tccgtcctgg cgcttctgtg gcttttcctg
     1621 gcccccggca gccaatgagg acactccatt cttggccata aaggccataa agatataaaa
     1681 ccttcaaaaa aaaaaaaaaa aaaaa
//
