LOCUS       NM_001108181            3449 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus acyl-CoA dehydrogenase family, member 11
            (Acad11), mRNA.
ACCESSION   NM_001108181 XM_001072510 XM_236582
VERSION     NM_001108181.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3449)
  AUTHORS   Valdecantos,M.P., Perez-Matute,P., Prieto-Hontoria,P.,
            Moreno-Aliaga,M.J. and Martinez,J.A.
  TITLE     Impact of dietary lipoic acid supplementation on liver
            mitochondrial bioenergetics and oxidative status on normally fed
            Wistar rats
  JOURNAL   Int J Food Sci Nutr 70 (7), 834-844 (2019)
   PUBMED   30764676
  REMARK    GeneRIF: A significant up-regulation of Cpt1a, Acadl and Sirt3, all
            beta-oxidation genes, along with a significant deacetylation of the
            forkhead transcription factor 3a (FOXO3A) was found in
            alpha-LA-treated animals.
REFERENCE   2  (bases 1 to 3449)
  AUTHORS   He,M., Pei,Z., Mohsen,A.W., Watkins,P., Murdoch,G., Van
            Veldhoven,P.P., Ensenauer,R. and Vockley,J.
  TITLE     Identification and characterization of new long chain acyl-CoA
            dehydrogenases
  JOURNAL   Mol Genet Metab 102 (4), 418-429 (2011)
   PUBMED   21237683
REFERENCE   3  (bases 1 to 3449)
  AUTHORS   Kikuchi,M., Hatano,N., Yokota,S., Shimozawa,N., Imanaka,T. and
            Taniguchi,H.
  TITLE     Proteomic analysis of rat liver peroxisome: presence of
            peroxisome-specific isozyme of Lon protease
  JOURNAL   J Biol Chem 279 (1), 421-428 (2004)
   PUBMED   14561759
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473954.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_236582.4, XM_001072510.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167762.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132286, SAMD00132291
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3449
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..3449
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /note="acyl-CoA dehydrogenase family, member 11"
                     /db_xref="GeneID:315973"
                     /db_xref="RGD:1306270"
     exon            1..214
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..2411
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /note="acyl-Coenzyme A dehydrogenase family, member 11;
                     ACAD-11"
                     /codon_start=1
                     /product="acyl-CoA dehydrogenase family member 11"
                     /protein_id="NP_001101651.1"
                     /db_xref="GeneID:315973"
                     /db_xref="RGD:1306270"
                     /translation="MEMDVTRDTVEVLPQHKFDIRSLEAYLNQHLPGFGSDHRAVLTV
                     TQYRSGQSNPTFFLQKGSQAYVLRKKPPGSLLPKAHKIDREFKVQKALFSVGFPVPKP
                     LLYCSNASIIGTEFYVMEHVQGRIFRDFSIPGVSPAERAAIYVSLVETLAWLHSLDIH
                     SLGLDRYGTGVGYCKRQVSTWTKQYQASAHQSIPAMDQLSTWLMRNLPDSDNEECLVH
                     GDFKLDNIVFHPKECRVIAVLDWELSTFGHPLSDLAHLSLFYFWPRTLPMINRGSHIQ
                     ENTGIPLMEELISIYCRRRGIDPNLPNWNFFMALSFFKLAGIAQGVYSRYLMGNNSSE
                     DSFLTANTVQPLAETGLQLSRRTLSTVPPQADAKSRLFAQSRRGQEVLTRVKQFMKQH
                     VFPAEKEVAEYYAQNGNSAEKWEHPLVIEKLKEMAKAEGLWNLFLPAVSGLSQVDYAL
                     IAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEQQKQQWLEPLLRGDITSVFCMTEP
                     NVSSSDATNMECSIQRDGGSYIVHGKKWWSSGAGNPKCKIAVVLGRTESPSVSRHKVH
                     SMILVPMDTPGVELIRPLSVFGYMDNVHGGHWEVHFNHVRVPASNLILGEGRGFEISQ
                     GRLGPGRIHHCMRSVGLAERILQIMCDRAVQREAFGKKLYEHEVVAHWIAKSRIAIEE
                     IRLLTLKAAHSIDTLGSAAARKEIAMIKVAAPKAVCKIADRAIQVHGGAGVSQDYPLA
                     NMYAIIRTLRLADGPDEVHLSAIAKMELQDQARQLKARM"
     exon            215..314
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            315..440
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            441..602
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            603..767
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            768..909
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1031
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1138
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1265
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            1266..1343
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1482
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1590
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..1689
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            1690..1756
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            1757..1842
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            1843..1914
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            1915..2069
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            2070..2186
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            2187..2296
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
     exon            2297..3449
                     /gene="Acad11"
                     /gene_synonym="RGD1306270"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctgccttgg cgctacgtct gtgtagtctg tggatccctc atttctatac acagggacag
       61 caggtgcagt catggagatg gatgtcacca gggacaccgt ggaagtgcta ccccagcaca
      121 agttcgacat caggtcccta gaggcctacc tgaatcagca cttgcccggc tttgggtcag
      181 atcaccgggc tgtgctgact gttactcaat acagatcagg acagtcgaac ccaacctttt
      241 ttctccagaa aggctcacaa gcatacgttc tcaggaagaa accacccggc tctcttcttc
      301 ccaaagcgca taagattgat agagaattca aggtccagaa agccttgttt tccgttggat
      361 ttcctgttcc caagcctctg ctgtactgca gcaatgcttc cattatcgga acggaatttt
      421 atgtgatgga acatgtgcag ggtcggatct tccgtgactt ttccattcct ggagttagcc
      481 cagcagaacg tgcagctata tatgtgtctt tggtagaaac cctggcatgg ctacactctc
      541 tggatataca ctcactggga ctggacagat acggtaccgg agtcgggtac tgcaaaaggc
      601 aggtgtccac ctggacaaag cagtaccagg cctccgccca tcagagcatc cctgccatgg
      661 accaactctc cacatggcta atgaggaacc tgccagatag cgacaatgag gagtgcctgg
      721 ttcatggaga tttcaagctg gacaacatag ttttccaccc caaagagtgt cgggttatag
      781 cagtgttgga ctgggagctc tcgaccttcg gccatccttt gtcagaccta gcccatcttt
      841 ccttgtttta cttttggccc cggacactgc ccatgataaa tcgaggctct cacattcaag
      901 agaacacagg aataccattg atggaagaac tgatttctat atactgccgt cgcaggggaa
      961 ttgatcctaa tctccctaac tggaatttct ttatggccct ttcatttttt aaattggctg
     1021 gaatagcaca gggggtctac agtagatacc tcatgggaaa taactcatct gaggatagct
     1081 ttctcactgc caatactgtg cagcctctgg cagaaactgg attacagctg tcaagaagaa
     1141 ctctcagtac tgtaccacca caggctgacg caaaaagccg gctgtttgca cagagcagga
     1201 gaggccagga agttctcact agggtgaagc agttcatgaa gcagcatgtc tttcctgctg
     1261 aaaaggaagt agctgaatac tatgctcaaa atggaaactc agcggaaaag tgggagcacc
     1321 ccttagtgat tgaaaaacta aaggaaatgg ccaaagcaga gggcctgtgg aacctgttct
     1381 tgcctgctgt gagcggtctc agccaggtgg actatgcctt gattgctgaa gagacaggaa
     1441 aatgcttttt cgctccagat gtttttaact gccaagcacc agacacaggc aacatggagg
     1501 tactacacct gtacggcagc gagcagcaga agcagcagtg gctggagcct ctcctgcgtg
     1561 gcgatatcac ctccgtcttc tgtatgacag agcccaacgt ctcatcaagc gatgccacaa
     1621 acatggagtg tagcatccag agagatggcg gtagctacat agttcatggc aagaagtggt
     1681 ggagcagcgg agctgggaat cccaagtgca aaatcgcagt tgtcttggga agaacggagt
     1741 ctccctctgt atccagacac aaagtgcaca gcatgatcct tgtgccgatg gacacccctg
     1801 gagtagagtt aataaggcct ttgtcggtgt tcggctacat ggacaatgtg catggcggac
     1861 actgggaggt ccattttaat cacgtacgtg ttcccgccag caatttaata ttgggtgaag
     1921 gcaggggctt tgaaatttcc caaggccgcc ttggacccgg aagaatccac cactgtatga
     1981 gatccgtggg cttggcagaa cgcattctgc agatcatgtg tgaccgggca gtgcagaggg
     2041 aggccttcgg gaagaagctc tatgagcatg aagtcgtggc tcactggatt gctaaaagcc
     2101 gtattgccat tgaggagatc cgcttactga ccttgaaagc cgctcacagc atagatactc
     2161 tgggcagtgc cgcagccagg aaggagattg caatgatcaa agtggccgcc cccaaagccg
     2221 tctgcaaaat agctgaccgg gccatccagg tgcacggagg cgcgggggtt tcccaggatt
     2281 accctctggc taacatgtat gccatcatac gcaccctgcg cttggcagac ggtcctgacg
     2341 aagtccatct ctcagcaatt gccaaaatgg agcttcagga ccaagccagg cagttgaaag
     2401 cccggatgtg atgggagcag ccctggggca cactcttgat cagctcaaaa cctctgtctc
     2461 catttcttga gtagtttgag cacaaggcta attattcacc tgtggtaacg tagcatctgt
     2521 tttgatcact gggttttact atgttaagga tcacacaaac gtgaggtaaa taggagaccc
     2581 cataactgtc actgagtcta gtgtctgggg ttagcagttg ctttatacac acgtggcctg
     2641 tgacgaggtc acactgagaa cagcagagct atttctggag tgtcagcata ataagtgtgt
     2701 tattttgtgt ttcaagagtt aagccccgag aatacacacc ccaggcctat tcaaccttgc
     2761 tttgaaacat acgtagctat acccccaccc ccttcagcag tgtttgtggg acttagttta
     2821 gcacctcaga gaaagctcta acttgaggat tttggagtgc caggtaagcc tcttcctaac
     2881 ccaacagagg aagttctggt gaaatctgaa tgcaggtgaa agttcacaag gaaatgtagc
     2941 atgtgaggag aacatcaagg agaagtcaag gccacttacg ttacgtagaa aaggctgagg
     3001 agatcgtcag tagtcagtgc tacatcaaag ctctgcagct ccctgagagc gggtctgatc
     3061 gggtgacacc agttctgtca gagctgccct tgcagtgcca ctgtgggcca ccacactgac
     3121 tacatcgaaa catcactagt atagcagagg aacaaaacgt ttagtttaaa tacaaatttt
     3181 cagttcagtt gctggggaag gcggttgagt atagttggaa aggcatgggt gggtacagct
     3241 acttattcaa gtacacgtgt gaaatctcat cacaaagaga aatgttgtaa atcaaaattt
     3301 ggcatccaaa taaacacagt aaatgtaaaa tacatactag attttgaaaa ctgaaaataa
     3361 ttaaaaatgt ctactggata atacctttac atattgatca tactttgaat tacattttgg
     3421 gaataccgga ttgaataaaa tatactcaa
//
