LOCUS       NM_001040019            1552 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus acetyl-Coenzyme A acyltransferase 1B (Acaa1b),
            mRNA.
ACCESSION   NM_001040019 XM_576485
VERSION     NM_001040019.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1552)
  AUTHORS   Ghys,K., Fransen,M., Mannaerts,G.P. and Van Veldhoven,P.P.
  TITLE     Functional studies on human Pex7p: subcellular localization and
            interaction with proteins containing a peroxisome-targeting signal
            type 2 and other peroxins
  JOURNAL   Biochem J 365 (Pt 1), 41-50 (2002)
   PUBMED   11931631
REFERENCE   2  (bases 1 to 1552)
  AUTHORS   Swinkels,B.W., Gould,S.J., Bodnar,A.G., Rachubinski,R.A. and
            Subramani,S.
  TITLE     A novel, cleavable peroxisomal targeting signal at the
            amino-terminus of the rat 3-ketoacyl-CoA thiolase
  JOURNAL   EMBO J 10 (11), 3255-3262 (1991)
   PUBMED   1680677
REFERENCE   3  (bases 1 to 1552)
  AUTHORS   Hijikata,M., Wen,J.K., Osumi,T. and Hashimoto,T.
  TITLE     Rat peroxisomal 3-ketoacyl-CoA thiolase gene. Occurrence of two
            closely related but differentially regulated genes
  JOURNAL   J Biol Chem 265 (8), 4600-4606 (1990)
   PUBMED   2307679
REFERENCE   4  (bases 1 to 1552)
  AUTHORS   Hijikata,M., Ishii,N., Kagamiyama,H., Osumi,T. and Hashimoto,T.
  TITLE     Structural analysis of cDNA for rat peroxisomal 3-ketoacyl-CoA
            thiolase
  JOURNAL   J Biol Chem 262 (17), 8151-8158 (1987)
   PUBMED   3036803
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001040019.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: J02749.1, BC098757.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-196               JAXUCZ010000008.1  127759374-127759569 c
            197-290             JAXUCZ010000008.1  127759141-127759234 c
            291-348             JAXUCZ010000008.1  127758752-127758809 c
            349-428             JAXUCZ010000008.1  127756775-127756854 c
            429-471             JAXUCZ010000008.1  127756493-127756535 c
            472-570             JAXUCZ010000008.1  127754565-127754663 c
            571-651             JAXUCZ010000008.1  127753504-127753584 c
            652-842             JAXUCZ010000008.1  127752311-127752501 c
            843-1022            JAXUCZ010000008.1  127751979-127752158 c
            1023-1078           JAXUCZ010000008.1  127751648-127751703 c
            1079-1224           JAXUCZ010000008.1  127751417-127751562 c
            1225-1552           JAXUCZ010000008.1  127750771-127751098 c
FEATURES             Location/Qualifiers
     source          1..1552
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1552
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /note="acetyl-Coenzyme A acyltransferase 1B"
                     /db_xref="GeneID:501072"
                     /db_xref="RGD:1562373"
     exon            1..196
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..1300
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /EC_number="2.3.1.9"
                     /EC_number="2.3.1.16"
                     /EC_number="2.3.1.155"
                     /note="peroxisomal 3-ketoacyl-CoA thiolase B;
                     3-ketoacyl-CoA thiolase B, peroxisomal; beta-ketothiolase
                     B; acetyl-CoA acyltransferase B; peroxisomal 3-oxoacyl-CoA
                     thiolase B"
                     /codon_start=1
                     /product="3-ketoacyl-CoA thiolase B, peroxisomal
                     precursor"
                     /protein_id="NP_001035108.2"
                     /db_xref="GeneID:501072"
                     /db_xref="RGD:1562373"
                     /translation="MHRLQVVLGHLAGRSESSSALQAAPCSAGFPQASASDVVVVHGR
                     RTPIGRAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLQPGAGAAMAR
                     IAQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMTLSERGN
                     PGNISSRLLENEKARDCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGC
                     FRAEIVPVTTTVLDDKGDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGGSTTAGNSS
                     QVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGL
                     TVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLN
                     ELKRRGRRAYGVVSMCIGTGMGAAAVFEYPGN"
     exon            197..290
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     exon            291..348
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     exon            349..428
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     exon            429..471
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     exon            472..570
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     exon            571..651
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     exon            652..842
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     exon            843..1022
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1078
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1224
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1552
                     /gene="Acaa1b"
                     /gene_synonym="RGD1562373"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctaatcggtg ggacgcacct ccgcgatgca tcggctgcag gtagtgctgg gccacctggc
       61 cggccggtcc gagtcgagct ccgcgctgca agccgcgccc tgctctgcgg gcttcccgca
      121 ggcctcggcc tccgacgtgg tggtggtgca cggacggcgc acccccatcg gccgcgccgg
      181 ccgcggcggc ttcaaggaca ccacccccga cgagcttctg tcggccgtgt tgaccgcggt
      241 tctccaggat gtgaagctaa agcctgagtg tctgggagac atctccgtgg gcaatgtgct
      301 tcagcccggg gccggagccg caatggcacg catcgcccag ttcctgagtg gcatcccaga
      361 gaccgtgcct ctgtcagcag tcaacagaca gtgttcatcg ggactgcagg cagtggccaa
      421 cattgctggt ggcatcagaa atgggtctta cgacattggc atggcctgtg gggtggagtc
      481 catgaccctg tctgagagag gcaaccctgg gaatatttcc tcccgtcttc tggagaacga
      541 gaaggccaga gactgcctga ttcctatggg gataacctcg gagaatgtgg ctgagcggtt
      601 tggcatctca cggcagaagc aggatgcctt cgcgctggcc tctcagcaga aggcagcaag
      661 cgcccagagc aaaggctgct tccgtgctga gatcgtgcct gtgacaacca ctgtcctcga
      721 tgacaagggt gacaggaaaa ccatcaccgt gtctcaggat gagggtgtcc gccccagcac
      781 caccatggag ggcctggcca agctgaagcc tgccttcaag gatggaggct ctaccacggc
      841 tggaaactcc agtcaggtga gtgatggagc agccgccgtc ctgctggccc ggaggtccaa
      901 ggctgaagaa ctgggcctcc ccatccttgg cgtcctgagg tcctatgcag tggtcggggt
      961 ccctcctgac atcatgggca tcggacctgc ctatgccatc cctgcggcct tgcagaaagc
     1021 agggctgact gtgaatgaca tagacatctt tgagatcaat gaggcctttg caagtcaggc
     1081 cctctactgt gtggagaagc tgggaattcc tgcagaaaag gtgaaccccc tggggggtgc
     1141 aatagccctg ggccaccccc tgggctgcac cggagcaagg caggtggtca cgctgctcaa
     1201 tgagctgaag cgccgaggca gacgggctta tggcgtggtg tccatgtgca tcgggactgg
     1261 gatgggagcc gctgctgtct ttgaataccc tgggaactga ggccctgact gcaggcacta
     1321 cccagagagt cctatagtag tgtctggaga gggatggtac agaagccatc ttcgtgggac
     1381 actcagcagt ggagggattt gtcacagcac tttaatttag aaaatgtaat cgcaatacgg
     1441 gcacaagggc atccaatcca ctcctctcag ttgaaccaaa gacagtgcac gtcacacgtg
     1501 accacaggac aacatgtttc tgagggacag tggcctcatg aatagtgggc at
//
