LOCUS       NM_134403               4521 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus ankyrin repeat and BTB domain containing 2
            (Abtb2), mRNA.
ACCESSION   NM_134403
VERSION     NM_134403.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4521)
  AUTHORS   Roy,A. and Pahan,K.
  TITLE     Ankyrin repeat and BTB/POZ domain containing protein-2 inhibits the
            aggregation of alpha-synuclein: implications for Parkinson's
            disease
  JOURNAL   FEBS Lett 587 (21), 3567-3574 (2013)
   PUBMED   24076025
REFERENCE   2  (bases 1 to 4521)
  AUTHORS   Hayashi,Y., Ichinose,M., Yuasa,H., Tatematsu,M. and Ishibashi,M.
  TITLE     Cca3, the mRNA level of which transiently decreases before
            initiation of DNA synthesis in regenerating rat liver cells
  JOURNAL   FEBS Lett 406 (1-2), 147-150 (1997)
   PUBMED   9109406
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB609664.1, AB000216.1, CV110237.1, DY545654.1, CB714885.1 and
            BQ203018.1.
            
            On Jul 17, 2010 this sequence version replaced NM_134403.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB000216.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                CB609664.1         13-40
            29-1915             AB000216.1         42-1928
            1916-1935           CV110237.1         263-282
            1936-3352           AB000216.1         1946-3362
            3353-3828           DY545654.1         212-687
            3829-3935           CB714885.1         360-466
            3936-4521           BQ203018.1         1-586               c
FEATURES             Location/Qualifiers
     source          1..4521
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q32"
     gene            1..4521
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /note="ankyrin repeat and BTB domain containing 2"
                     /db_xref="GeneID:171440"
                     /db_xref="RGD:620724"
     exon            1..1283
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     CDS             401..3475
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /note="ankyrin repeat and BTB (POZ) domain containing 2;
                     confluent 3Y1 cell-associated protein"
                     /codon_start=1
                     /product="ankyrin repeat and BTB/POZ domain-containing
                     protein 2"
                     /protein_id="NP_599230.2"
                     /db_xref="GeneID:171440"
                     /db_xref="RGD:620724"
                     /translation="MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNS
                     SAPQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEG
                     DVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQS
                     AVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTR
                     ISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAE
                     LWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLA
                     TCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLR
                     CPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQA
                     ARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFNQDLGFRMLNCGRTDLISQAIE
                     ALGPDGVNTMDDQGLTPLMYACATGDEAMVQMLIDAGANLDIQVPSNSPRHPSVHPDS
                     RHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVS
                     LLLSRGADPLLSMLEANGMASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLS
                     LEEILAEGVEESDTSSQGSSEGPVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGV
                     PWKLHIWIESLRTSFSQSRYSVVQGLLRDFSSIKEEEYNEELVTEGLQLMFDILKTSK
                     NDSVLQQLATIFTHCYGTSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFY
                     AHKVLLVTASNRFKTLMTNKSEQDGDNSKTIEISDIKYHIFQMLMQYLYYGGTESMEI
                     PTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEG
                     FFLKHMKALLEQDAFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSVYVTSRV"
     exon            1284..1430
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1644
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            1645..1797
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            1798..1963
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            1964..2053
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            2054..2155
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2252
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            2253..2388
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            2389..2615
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            2616..2794
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            2795..2900
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            2901..3003
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            3004..3094
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            3095..3163
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            3164..3277
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
     exon            3278..4504
                     /gene="Abtb2"
                     /gene_synonym="Cca3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgctttctca ccggctggtc cgggacggat agccggcgcc tcgctcttcg gtgaccgccc
       61 cattctctcg ggattccttc tctgtggtga cggacgctct agacgctcgg taagggaagc
      121 tgaggctggc ggcgggagtt cagaggagga gcgcggagag gttgctcgct gacagcggcg
      181 cggctggacg cggacggcgt cgggctctgg ccggctgaga gcttcgccca ccttccccgc
      241 ggcctgtgcg caggcgatgc tgcggccccg aggcgcggcg cggcgagcag ggagggcgcc
      301 tccgagagcc tagagctggt ttccgtcctc ttccccgggg caagtgggca tggaacagtg
      361 agagcccctc gctcggcgag gccgcgcgcg gaggctcccc atggccggga cgtacagctc
      421 cacattgaag actctggagg acttgacctt ggactccggg tatggggccg gcgactcctg
      481 ccgctcgctc agcctttcgt cttccaagtc caactcgcag gcgctcaact cttcggcgcc
      541 gcagcaccgc ggggcggcct ggtggtgcta ctccggctcc atgaacagcc gccacaacag
      601 ctgggacacc gtgaacacag tgctgcccga ggatcccgaa gtggccgacc tcttctcgcg
      661 ctgcccgcgg ctcccggagc tagaggagtt cccttggacc gagggagacg tggctcgggt
      721 gctccgcaaa agcgtcggcg gccggaggct gccctcattc tccgccgagg ctgtgaggcg
      781 cttggccgga ctcctccgcc gggcgctcat ccgcgtggcc cgggaggcgc agcgcctaag
      841 cgtgctgcac gccaagtgta cccgcttcga ggtgcagagt gcggtgcgcc tggtgcacag
      901 ctgggcgctg gccgagagct gcgcgctggc agcggtcaag gcgttgtccc tctatagcat
      961 gagcgctggc gatgggctgc gccgcggcaa gtcggcacgc tgcggcctca ctttctccgt
     1021 gggccgtttc ttccgttgga tggtggacac tcgcatctcc gtgcgcatcc atgagtatgc
     1081 ggccatctcg cttacggctt gcatggagaa cttggtggag gagatccggg ctagggtcct
     1141 ggcgagtcag agccctgatg gcggaggggc aggaggcgga gaggtatccg ctgaggcctt
     1201 ggagatggtc atcaacaacg atgccgagct ctggggagtc ctgcaaccct atgagcatct
     1261 catctgcggc aagaacgcca atggtgtcct ctccctccct gcctacttca gtccctacaa
     1321 tggtgggtcc ctgggccatg atgagcgagc agatgcctat gctcagctgg agcttcggac
     1381 actggagcag tcactcctgg ctacctgtgt gggcagcatc tccgagctga gtgatctggt
     1441 ctctcgagcc atgcaccaca tgcaggggcg ccaccctctg tgcccaggca ccagccctgc
     1501 tcgccaggcc cgccagccac cacagcccat cacatggtcc cccgatgctc tccatacact
     1561 ctactacttc ctgagatgtc cacagatgga gtccatggag aaccccaacc tggatccccc
     1621 aagaatgacc ctgaataatg aacggccctt catgctgctg ccaccactga tggagtggat
     1681 gcgggtggca atcacctatg cagaacaccg tcgcagcctc actgtggaca gtggcgatat
     1741 ccggcaggca gcccggctgc tgctaccagg cctggactgc gagccccgcc agctcaaacc
     1801 cgagtgctgc ttcagttcct tccggaggct ggacgctcga gctgctactg aacgcttcaa
     1861 ccaggacctg ggcttccgca tgctcaactg tgggagaaca gacctcatca gccaggccat
     1921 cgaggccctg ggcccagacg gggtgaacac aatggatgac cagggtctga caccgctaat
     1981 gtacgcctgt gctactgggg atgaagccat ggtccagatg ctcatcgatg ctggagcaaa
     2041 cttggatatc caggtcccaa gcaactctcc caggcatcct tctgtccatc cagacagcag
     2101 gcactggacc tccctgacat tcgcggtgct gcacggacac atctctgtag tgcagctgct
     2161 acttgatgct ggtgcccatg tggagggctc ggccgtgaac agtggggagg acagctatgc
     2221 cgagacaccc cttcagctgg cctctgcagc cgggaactat gagctggtga gcttgctact
     2281 gagccgaggt gccgaccccc tcctcagcat gctggaagcc aatggcatgg cttcttccct
     2341 ccatgaggat atgaactgct tcagccactc agctgcccat ggccacagga atgtcttgag
     2401 gaagctcctg actcagccac agcaggctaa agcagatgtg ctgtccctag aagagatctt
     2461 ggctgagggc gtggaggaaa gcgacacatc gagccagggc agtagcgagg ggcctgtgag
     2521 gttaagccgg acccgaacga aggccctgca ggaagccatg tactacagtg ctgaacacgg
     2581 ctacgtggac atcacgatgg agctgagggc actaggtgtc ccctggaagc tgcacatctg
     2641 gatagagtct ctgcggacct ctttctcaca gtcacggtac tcggtggtgc agggcctcct
     2701 gagagatttc agctccatca aggaggagga gtacaatgag gagctggtga cagaaggctt
     2761 gcagctcatg tttgacatcc tcaagaccag caaaaatgac tccgtcctcc agcagctggc
     2821 caccatcttc actcactgct atggcaccag ccccatcccc agcatcccgg agatccggaa
     2881 gaccctgcca gccaggctag atcctcactt tctgaacaac aaggagatgt ctgatgtaac
     2941 cttcctcgtg gaaggaaagc tgttttatgc acacaaagtc cttttggtga cagcatctaa
     3001 caggttcaaa accttaatga ccaataagtc agagcaagat ggggacaaca gcaaaaccat
     3061 tgagatcagc gacatcaagt accacatctt tcagatgctg atgcagtacc tgtactatgg
     3121 aggaacagag tccatggaga tccccacggc tgacatcctg cagctcctgt cagctgccaa
     3181 cctgttccag ctagatgccc tgcagagaca ctgtgagatc ctgtgctccc agacccttag
     3241 tgtggagagt gctgtcaaca cctacaaata cgccaagatc cacaacgccc cagagctggc
     3301 cctcttctgt gaaggcttct tcctcaagca catgaaggcc ctgctggagc aggatgcctt
     3361 ccggcagctc atctatggcc gaagcagcaa agtccagggc ctggacccac tgcaggatct
     3421 gcagagcacc ctagctgagc gagtacattc tgtctacgtc acctcccggg tgtgagccag
     3481 ggtggatggt gactgctatc tgagggtgta caaaggtctg ttaaagccag aaaccaccag
     3541 cgacaccccc agtggaggga ggcttgtagg ccttctgggg taggctctcg gggggtacgt
     3601 cctgctcttc ccctagatta ccctctgtgg tgttgactga tcctgaggtg gaaggagagt
     3661 ccacttcact gttgctcggc cagtaactgg ccaggggtgt gacgtaattg caccctgagg
     3721 gctaccctgt gccctctccc ctccagtggc tcagcgtcga gccgatccac ctcagcacca
     3781 gccatcctgg ctggggatgt taggatcaca ggcattctta tgaatgtaga aagtgtccga
     3841 gcccaggcca ctgggtgcag gagccgctat gtttggtttc ctaacagaga gaggctaagt
     3901 cctgccctcc aagctgtgcc tttgaaaggg ctgggccctg ttggtgaaaa ccagacctcc
     3961 agtgccctcc ctacaagact actaacgaga gtctgaactg ggaatccctg agcaccgggt
     4021 atgctgggct acaggagctg gcagccacag gaggcccagc cccatcatgt ctgtaggctg
     4081 aggcagcagg gcttcaatgg cctcaagtgc agggcgcctt ccactcaggg ctggggtgca
     4141 agagcacact tctcacctgg gttccgtgac tctggggcat gaaggacagg gccttggtgg
     4201 aagagaagct gtgtcctctc ccctcctgtc ctcagtcttg gctccccatc ctctgacctg
     4261 tttgtggaca gacgctggga cagcatcaag aacagctacc ttagaaacta tttattcatc
     4321 agaagccccc agggcttgca atcctggaac aatattttca acttgctgct tgtgctggat
     4381 gtacaaaaga atgaatggta ttttattgct gtaatattgt atgatactgt aactatacct
     4441 taatgttgtt acttactgta aatgtactat ggttttatca acaataaaca ctcattaaca
     4501 ttgaaaaaaa aaaaaaaaaa a
//
