LOCUS       NM_001009633            1513 bp    mRNA    linear   ROD 04-OCT-2024
DEFINITION  Rattus norvegicus abraxas 1, BRCA1 A complex subunit (Abraxas1),
            mRNA.
ACCESSION   NM_001009633 XM_214001
VERSION     NM_001009633.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1513)
  AUTHORS   Wang,B., Hurov,K., Hofmann,K. and Elledge,S.J.
  TITLE     NBA1, a new player in the Brca1 A complex, is required for DNA
            damage resistance and checkpoint control
  JOURNAL   Genes Dev 23 (6), 729-739 (2009)
   PUBMED   19261749
REFERENCE   2  (bases 1 to 1513)
  AUTHORS   Feng,L., Huang,J. and Chen,J.
  TITLE     MERIT40 facilitates BRCA1 localization and DNA damage repair
  JOURNAL   Genes Dev 23 (6), 719-728 (2009)
   PUBMED   19261748
REFERENCE   3  (bases 1 to 1513)
  AUTHORS   Shao,G., Patterson-Fortin,J., Messick,T.E., Feng,D., Shanbhag,N.,
            Wang,Y. and Greenberg,R.A.
  TITLE     MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to
            DNA double-strand breaks
  JOURNAL   Genes Dev 23 (6), 740-754 (2009)
   PUBMED   19261746
REFERENCE   4  (bases 1 to 1513)
  AUTHORS   Liu,Z., Wu,J. and Yu,X.
  TITLE     CCDC98 targets BRCA1 to DNA damage sites
  JOURNAL   Nat Struct Mol Biol 14 (8), 716-720 (2007)
   PUBMED   17643121
REFERENCE   5  (bases 1 to 1513)
  AUTHORS   Wang,B., Matsuoka,S., Ballif,B.A., Zhang,D., Smogorzewska,A.,
            Gygi,S.P. and Elledge,S.J.
  TITLE     Abraxas and RAP80 form a BRCA1 protein complex required for the DNA
            damage response
  JOURNAL   Science 316 (5828), 1194-1198 (2007)
   PUBMED   17525340
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088408.1.
            
            On Jan 13, 2005 this sequence version replaced XM_214001.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088408.1, SRR8487227.155437.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132300, SAMD00132303
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1513
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..1513
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /note="abraxas 1, BRCA1 A complex subunit"
                     /db_xref="GeneID:289468"
                     /db_xref="RGD:1305287"
     exon            1..136
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..1267
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /note="coiled-coil domain-containing protein 98;
                     coiled-coil domain containing 98; family with sequence
                     similarity 175, member A"
                     /codon_start=1
                     /product="BRCA1-A complex subunit Abraxas 1"
                     /protein_id="NP_001009633.1"
                     /db_xref="GeneID:289468"
                     /db_xref="RGD:1305287"
                     /translation="MEGESTLGVLSGFVLGALTFQHLNTDSDTEGLLLGEMKGEAKNS
                     ITDSQMDSVKVVYTIDIQKYIPCYRLFSFYNSLGEVNEHALKKILSNVKKTVVGWYKF
                     RRHSDQIMTFREQLLHRNLQTHLSSPELVFLLLTPSITTESCCTHCLEHGLYKPQSGL
                     FHKVPLVVTNLGMSDQLGYKTESVSCTSTVFSRAVRTYSSQFFNEDGSLKEVRKINEM
                     YAAIQEELKTICQKVEQSEREVEKLLMDVNRLKEVRKKQQAQAKGAGEKSQNHPQENI
                     LLCQALRTFFPESRVLHSCVISLKNRHISHSGCNTDHHLDVVDKLTLMVEYVYSPEAS
                     PAPAAPLSKRKALDTQDQWPAKRPRLLESESRPGPAFRGSHQDKASSSSLDIDTEVGS
                     PEDDTDYPRSPTF"
     exon            137..227
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /inference="alignment:Splign:2.1.0"
     exon            228..264
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /inference="alignment:Splign:2.1.0"
     exon            265..331
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /inference="alignment:Splign:2.1.0"
     exon            332..525
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /inference="alignment:Splign:2.1.0"
     exon            526..645
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /inference="alignment:Splign:2.1.0"
     exon            646..730
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /inference="alignment:Splign:2.1.0"
     exon            731..842
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /inference="alignment:Splign:2.1.0"
     exon            843..1452
                     /gene="Abraxas1"
                     /gene_synonym="Ccdc98; Fam175a; RGD1305287"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgtcgggcgc cgcgatagtg gctgtggcgg tagcgactga ggcggcagta tggagggcga
       61 gagcacgttg ggggtgttgt ctggcttcgt gcttggcgcg ctcaccttcc agcatctcaa
      121 cactgactca gatacggagg gtcttctcct cggtgaaatg aaaggtgaag ccaagaatag
      181 catcactgac tcacagatgg acagcgttaa agtcgtctac acaattgaca ttcagaaata
      241 tattccatgc taccggcttt ttagctttta taattcttta ggtgaagtaa atgaacacgc
      301 actgaagaaa attctttcaa atgtcaaaaa gactgtggtg ggttggtata aattccgtcg
      361 tcactcggat cagataatga catttagaga gcagttgctc cacagaaact tacagacgca
      421 tctttcaagc ccagagcttg tttttctgtt gttaacacca agtataacaa cagagagctg
      481 ctgcactcac tgcctggaac acggcctgta caaacctcaa agtgggcttt ttcataaggt
      541 acctttggtg gttaccaatc tgggaatgtc tgatcaactg ggttataaaa cagagtctgt
      601 ttcctgtacg tccactgtct ttagcagagc tgtgaggaca tacagttctc aattttttaa
      661 tgaagatgga tcattaaagg aagtacgtaa gataaatgaa atgtatgctg ctatacaaga
      721 agaattaaag actatatgcc aaaaagttga acaaagtgaa cgagaagtag agaaactatt
      781 gatggatgta aaccgattaa aagaagttag aaaaaaacag caagcacagg ctaaaggagc
      841 aggagagaag agccaaaacc atccccagga gaacattctc ctctgccaag ctttacgaac
      901 attctttcca gagtctcgag ttcttcactc ttgcgttatt tctttgaaaa atagacatat
      961 ttctcacagt gggtgtaaca ctgaccacca tcttgatgtg gtggataagc taaccttaat
     1021 ggtggagtac gtttacagcc ctgaagctag tccagcacct gcagccccac tgagcaaacg
     1081 taaagctcta gacacacaag atcagtggcc tgcgaagaga ccacggctgc tagagtcaga
     1141 aagcagacct gggccagcat ttcgaggcag tcaccaggac aaagcctcct caagcagcct
     1201 cgatatagac acagaggtgg ggagcccgga agatgatact gactaccctc gctctcccac
     1261 attttgattc tttgtagagg acatttttta ctagactgga gtttagggca cttattttta
     1321 ctctttgctt cctggagtaa tagagttcat gcttttactc tattcagctg tttgtaatac
     1381 atggatattt ttactgttca actgcttata atatataggt aagttaatat tttataaagt
     1441 atcttaaaaa ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1501 aaaaaaaaaa aaa
//
