LOCUS       NM_023094               1599 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus histo-blood group ABO system transferase 3
            (Abo3), mRNA.
ACCESSION   NM_023094 XM_342394
VERSION     NM_023094.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1599)
  AUTHORS   Turcot,A.L., Blancher,A., Le Moullac-Vaidye,B., Despiau,S.,
            Rocher,J., Roubinet,F., Szpirer,C. and Le Pendu,J.
  TITLE     Cloning of a rat gene encoding the histo-blood group B enzyme: rats
            have more than one Abo gene
  JOURNAL   Glycobiology 13 (12), 919-928 (2003)
   PUBMED   12799344
  REMARK    GeneRIF: data indicate that rats have at least two distinct Abo
            genes, one monomorphic gene encoding a B-specific enzyme and one or
            more genes in some cases encoding an A-specific enzyme
REFERENCE   2  (bases 1 to 1599)
  AUTHORS   Iwamoto,S., Kumada,M., Kamesaki,T., Okuda,H., Kajii,E., Inagaki,T.,
            Saikawa,D., Takeuchi,K., Ohkawara,S., Takahashi,R., Ueda,S.,
            Inoue,S., Tahara,K., Hakamata,Y. and Kobayashi,E.
  TITLE     Rat encodes the paralogous gene equivalent of the human histo-blood
            group ABO gene. Association with antigen expression by
            overexpression of human ABO transferase
  JOURNAL   J Biol Chem 277 (48), 46463-46469 (2002)
   PUBMED   12237302
REFERENCE   3  (bases 1 to 1599)
  AUTHORS   Cailleau-Thomas,A., Le Moullac-Vaidye,B., Rocher,J., Bouhours,D.,
            Szpirer,C. and Le Pendu,J.
  TITLE     Cloning of a rat gene encoding the histo-blood group A enzyme.
            Tissue expression of the gene and of the A and B antigens
  JOURNAL   Eur J Biochem 269 (16), 4040-4047 (2002)
   PUBMED   12180981
  REMARK    GeneRIF: The complete coding sequence of a BDIX rat gene homologous
            to the human ABO gene was determined. It had strong
            UDP-GalNAc:Fucalpha1,2GalalphaGalNAc transferase activity and a
            small UDP-Gal:Fucalpha1,2GalalphaGal transferase activity.
REFERENCE   4  (bases 1 to 1599)
  AUTHORS   Olson,F.J., Johansson,M.E., Klinga-Levan,K., Bouhours,D.,
            Enerback,L., Hansson,G.C. and Karlsson,N.G.
  TITLE     Blood group A glycosyltransferase occurring as alleles with high
            sequence difference is transiently induced during a Nippostrongylus
            brasiliensis parasite infection
  JOURNAL   J Biol Chem 277 (17), 15044-15052 (2002)
   PUBMED   11842091
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Oct 27, 2022 this sequence version replaced NM_023094.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB081649.1, AB081651.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760400,
                                           SAMEA5760476 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-90                JAXUCZ010000003.1  30141941-30142030
            91-160              JAXUCZ010000003.1  30151101-30151170
            161-217             JAXUCZ010000003.1  30151795-30151851
            218-265             JAXUCZ010000003.1  30153136-30153183
            266-301             JAXUCZ010000003.1  30154420-30154455
            302-436             JAXUCZ010000003.1  30155118-30155252
            437-1599            JAXUCZ010000003.1  30157967-30159129
FEATURES             Location/Qualifiers
     source          1..1599
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..1599
                     /gene="Abo3"
                     /gene_synonym="Abo; Abol1"
                     /note="histo-blood group ABO system transferase 3"
                     /db_xref="GeneID:65270"
                     /db_xref="RGD:628609"
     exon            1..90
                     /gene="Abo3"
                     /gene_synonym="Abo; Abol1"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..1124
                     /gene="Abo3"
                     /gene_synonym="Abo; Abol1"
                     /EC_number="2.4.1.37"
                     /EC_number="2.4.1.40"
                     /note="ABO blood group (alpha
                     1-3-N-acetylgalactosaminyltransferase, alpha
                     1-3-galactosyltransferase); B blood group
                     galactosyltransferase; blood group A glycosyltransferase
                     1; NAGAT 1; a transferase; b transferase; cis-AB
                     transferase 1; histo-blood group A transferase; ABO blood
                     group (transferase A, alpha
                     1-3-N-acetylgalactosaminyltransferase; transferase B,
                     alpha 1-3-galactosyltransferase); ABO blood group-like 1;
                     globoside alpha-1,3-N-acetylgalactosaminyltransferase 1;
                     ABO blood group (transferase B, alpha
                     1-3-galactosyltransferase); histo-blood group B
                     transferase; fucosylglycoprotein
                     3-alpha-galactosyltransferase; fucosylglycoprotein
                     alpha-N-acetylgalactosaminyltransferase;
                     glycoprotein-fucosylgalactoside
                     alpha-galactosyltransferase;
                     glycoprotein-fucosylgalactoside
                     alpha-N-acetylgalactosaminyltransferase;
                     N-acetylgalactosaminyltransferase A blood group-like
                     enzyme; alpha 1-3-N-acetylgalactosaminyltransferase-like
                     1"
                     /codon_start=1
                     /product="histo-blood group ABO system transferase 1"
                     /protein_id="NP_075582.3"
                     /db_xref="GeneID:65270"
                     /db_xref="RGD:628609"
                     /translation="MDLRGRPKCYSLHLGILPFIVLVLVFFGYGFLSHKIQEFRNPGG
                     ETCMATRQTDVQKVVSVPRMAYPQPNVLTPIRNDVLVFTPWLAPIIWEGTFNIDILNE
                     QFKLQNTTIGLTVFAIKKYVVFLKLFLETAEQHFMVGHKVIYYVFTDRPSDVPQVPLG
                     AGRKLVVLTVRNYTRWQDVSMHRMEMISHFSEQRFQHEVDYLVCGDVDMKFSDHVGVE
                     ILSALFGTLHPGFYRSRRESFTYERRPKSQAYIPRDEGDFYYAGGFFGGSVVEVHHLT
                     KACHQAMVEDQANGIEAVWHDESHLNKYLLYHKPTKVLSPEYVWDQKLLGWPSIMKKL
                     RYVAVPKNHQAIRN"
     exon            91..160
                     /gene="Abo3"
                     /gene_synonym="Abo; Abol1"
                     /inference="alignment:Splign:2.1.0"
     exon            161..217
                     /gene="Abo3"
                     /gene_synonym="Abo; Abol1"
                     /inference="alignment:Splign:2.1.0"
     exon            218..265
                     /gene="Abo3"
                     /gene_synonym="Abo; Abol1"
                     /inference="alignment:Splign:2.1.0"
     exon            266..301
                     /gene="Abo3"
                     /gene_synonym="Abo; Abol1"
                     /inference="alignment:Splign:2.1.0"
     exon            302..436
                     /gene="Abo3"
                     /gene_synonym="Abo; Abol1"
                     /inference="alignment:Splign:2.1.0"
     exon            437..1599
                     /gene="Abo3"
                     /gene_synonym="Abo; Abol1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagtctgcta tgtgcctgag gtcttggctg tgctgtccaa cttactgtgc agaagaggaa
       61 ccatcccggg ccttgccatg gacctcagag gaagaccgaa atgctactca cttcaccttg
      121 gaatccttcc cttcattgtg cttgtcttag tcttctttgg ctatggattc ctgagccaca
      181 aaatccagga attcaggaac ccaggaggtg agacttgcat ggctaccagg cagacggatg
      241 tccagaaagt tgtaagtgtg ccaaggatgg cctatccaca gccaaacgtg ctaacaccca
      301 ttaggaatga tgttcttgtc ttcactcctt ggctggctcc catcatctgg gaggggacct
      361 tcaacatcga catactgaat gagcagttca agcttcagaa taccacaatt ggactgactg
      421 tgtttgccat caaaaagtat gtggtgttcc tgaaactctt cctggagacg gcagagcagc
      481 acttcatggt gggacacaag gtcatctatt atgtattcac tgaccggcca tctgatgtgc
      541 cacaggtgcc cctgggcgca gggcggaagc tggtggtgct aactgtgcgc aactacaccc
      601 gctggcagga cgtgtccatg cacaggatgg agatgatcag ccacttctca gagcagcgct
      661 ttcagcatga ggtggactat ctggtgtgtg gagatgtgga catgaagttc agtgaccacg
      721 tgggtgtgga gattctctca gcgctctttg gcaccctgca tcctggcttc taccgtagcc
      781 gacgagagtc ctttacctat gagcgccggc caaagtctca ggcctacatc cccagggatg
      841 agggtgactt ttactatgca gggggtttct ttgggggatc agtggtggag gtgcaccatc
      901 tcaccaaggc ctgccaccag gctatggtag aggaccaggc caatggtatt gaggctgtgt
      961 ggcatgacga gagccatttg aacaagtacc tgctatacca taagcctaca aaggtgctgt
     1021 ccccagagta tgtgtgggac cagaagctgc tgggctggcc ctccatcatg aagaagctga
     1081 gatatgtggc cgtgcccaag aaccatcagg cgatcaggaa ctgatagctg aatccctgtt
     1141 ggagaggccc tacctgtagc cagtctgtgg aaggatttga gagacattgc ttactgtcac
     1201 cctctatttc acctcagagt ccagcagagc ccagaaccac ttggcttacc acatattgag
     1261 tccctagtgt gtcaaccacc ttcatctccc atgtatctcc ttgtatttaa tgagctggta
     1321 gagccttcaa aacatgggag aaactgtcat gcagttacct ggtggccctt gcatcctcag
     1381 tttgggttgt tccttcctct tctgtgagga ttgacagagg gctagtgccc atagcaacag
     1441 acaggaaggc agagagagtc atcctaaagg caccagatat tcttatgttc agctctgatg
     1501 gggccaagca gcaccttgtg cccagtgcct ctcctcatgt taggcttatc tgttaatggc
     1561 tagttattct ttccttggaa taaatgtatc tctacatga
//
