LOCUS       NM_001271298            1580 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus histo-blood group ABO system transferase 2
            (Abo2), mRNA.
ACCESSION   NM_001271298 XM_002726090 XM_215986
VERSION     NM_001271298.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1580)
  AUTHORS   Risch,H.A., Yu,H., Lu,L. and Kidd,M.S.
  TITLE     ABO blood group, Helicobacter pylori seropositivity, and risk of
            pancreatic cancer: a case-control study
  JOURNAL   J Natl Cancer Inst 102 (7), 502-505 (2010)
   PUBMED   20181960
REFERENCE   2  (bases 1 to 1580)
  AUTHORS   Wolpin,B.M., Kraft,P., Gross,M., Helzlsouer,K.,
            Bueno-de-Mesquita,H.B., Steplowski,E., Stolzenberg-Solomon,R.Z.,
            Arslan,A.A., Jacobs,E.J., Lacroix,A., Petersen,G., Zheng,W.,
            Albanes,D., Allen,N.E., Amundadottir,L., Anderson,G.,
            Boutron-Ruault,M.C., Buring,J.E., Canzian,F., Chanock,S.J.,
            Clipp,S., Gaziano,J.M., Giovannucci,E.L., Hallmans,G.,
            Hankinson,S.E., Hoover,R.N., Hunter,D.J., Hutchinson,A., Jacobs,K.,
            Kooperberg,C., Lynch,S.M., Mendelsohn,J.B., Michaud,D.S.,
            Overvad,K., Patel,A.V., Rajkovic,A., Sanchez,M.J., Shu,X.O.,
            Slimani,N., Thomas,G., Tobias,G.S., Trichopoulos,D., Vineis,P.,
            Virtamo,J., Wactawski-Wende,J., Yu,K., Zeleniuch-Jacquotte,A.,
            Hartge,P. and Fuchs,C.S.
  TITLE     Pancreatic cancer risk and ABO blood group alleles: results from
            the pancreatic cancer cohort consortium
  JOURNAL   Cancer Res 70 (3), 1015-1023 (2010)
   PUBMED   20103627
REFERENCE   3  (bases 1 to 1580)
  AUTHORS   Bijanzadeh,M., Ramachandra,N.B., Mahesh,P.A., Savitha,M.R.,
            Manjunath,B.S. and Jayaraj,B.S.
  TITLE     Lack of association between asthma and ABO blood group
  JOURNAL   Lung 187 (6), 389-392 (2009)
   PUBMED   19771478
REFERENCE   4  (bases 1 to 1580)
  AUTHORS   Banales,J.M., Masyuk,T.V., Bogert,P.S., Huang,B.Q., Gradilone,S.A.,
            Lee,S.O., Stroope,A.J., Masyuk,A.I., Medina,J.F. and LaRusso,N.F.
  TITLE     Hepatic cystogenesis is associated with abnormal expression and
            location of ion transporters and water channels in an animal model
            of autosomal recessive polycystic kidney disease
  JOURNAL   Am J Pathol 173 (6), 1637-1646 (2008)
   PUBMED   18988797
REFERENCE   5  (bases 1 to 1580)
  AUTHORS   Fullmer,J.M., Riedl,M., Williams,F.G., Sandrin,M. and Elde,R.
  TITLE     Enzymes that synthesize the IB4 epitope are not sufficient to
            impart IB4 binding in dorsal root ganglia of rat
  JOURNAL   J Comp Neurol 501 (1), 70-82 (2007)
   PUBMED   17206613
REFERENCE   6  (bases 1 to 1580)
  AUTHORS   Olson,F.J., Johansson,M.E., Klinga-Levan,K., Bouhours,D.,
            Enerback,L., Hansson,G.C. and Karlsson,N.G.
  TITLE     Blood group A glycosyltransferase occurring as alleles with high
            sequence difference is transiently induced during a Nippostrongylus
            brasiliensis parasite infection
  JOURNAL   J Biol Chem 277 (17), 15044-15052 (2002)
   PUBMED   11842091
REFERENCE   7  (bases 1 to 1580)
  AUTHORS   Volkova,K.I. and Godes,I.E.
  TITLE     [Genetic markers of the ABO blood system in pulmonary sarcoidosis
            patients of different ethnic origin]
  JOURNAL   Klin Med (Mosk) 74 (8), 44-46 (1996)
   PUBMED   9036208
REFERENCE   8  (bases 1 to 1580)
  AUTHORS   Pandey,M., Gautam,A. and Shukla,V.K.
  TITLE     ABO and Rh blood groups in patients with cholelithiasis and
            carcinoma of the gall bladder
  JOURNAL   BMJ 310 (6995), 1639 (1995)
   PUBMED   7795450
REFERENCE   9  (bases 1 to 1580)
  AUTHORS   Chobanov,R.E. and Salekhov,A.A.
  TITLE     [The distribution of ABO system blood groups in patients with
            unilocular echinococcosis]
  JOURNAL   Med Parazitol (Mosk) (2), 18-20 (1990)
   PUBMED   2142987
REFERENCE   10 (bases 1 to 1580)
  AUTHORS   Fedorova,G.I., Slepushkin,A.N., Popova,N.S., Mel'nichenko,E.I. and
            Markina,I.A.
  TITLE     [Correlations of the antigenic specificity of human blood with the
            levels of antihemagglutinins to influenza viruses]
  JOURNAL   Vopr Virusol 28 (1), 54-57 (1983)
   PUBMED   6189297
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Apr 12, 2023 this sequence version replaced NM_001271298.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               JAXUCZ010000003.1  30409553-30409660
            109-178             JAXUCZ010000003.1  30419731-30419800
            179-235             JAXUCZ010000003.1  30420418-30420474
            236-271             JAXUCZ010000003.1  30422645-30422680
            272-406             JAXUCZ010000003.1  30423165-30423299
            407-1580            JAXUCZ010000003.1  30425304-30426477
FEATURES             Location/Qualifiers
     source          1..1580
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..1580
                     /gene="Abo2"
                     /gene_synonym="NAGAT 2"
                     /note="histo-blood group ABO system transferase 2"
                     /db_xref="GeneID:296504"
                     /db_xref="RGD:1311152"
     exon            1..108
                     /gene="Abo2"
                     /gene_synonym="NAGAT 2"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..1094
                     /gene="Abo2"
                     /gene_synonym="NAGAT 2"
                     /note="a transferase; b transferase; cis-AB transferase 2;
                     histo-blood group A transferase; histo-blood group B
                     transferase; b blood group galactosyltransferase; blood
                     group A glycosyltransferase 2; putative blood group A
                     transferase T2; fucosylglycoprotein
                     3-alpha-galactosyltransferase; fucosylglycoprotein
                     alpha-N-acetylgalactosaminyltransferase;
                     glycoprotein-fucosylgalactoside
                     alpha-galactosyltransferase; transferase B, alpha
                     1-3-galactosyltransferase);
                     glycoprotein-fucosylgalactoside
                     alpha-N-acetylgalactosaminyltransferase; ABO blood group
                     (transferase A, alpha
                     1-3-N-acetylgalactosaminyltransferase; ABO blood group
                     (alpha 1-3-N-acetylgalactosaminyltransferase, alpha
                     1-3-galactosyltransferase)"
                     /codon_start=1
                     /product="histo-blood group ABO system transferase"
                     /protein_id="NP_001258227.3"
                     /db_xref="GeneID:296504"
                     /db_xref="RGD:1311152"
                     /translation="MKDLRLGRLKCYSLHLGILPLTVLVLVFFCFVCLSLRSQEWGHP
                     GAVNRKAYPQPRVLTPTRTDVLVLTPWLAPIIWEGTFNIDILNEQFRLRNTTIGLTVF
                     AIKKYVVFLKLFLETAEQHFMVGHKVIYYVFTDRPADVPQVPLGAGRRLVVLAVRNYT
                     RWQDVSMHRMEIISHFSEQRFWHEVDYLVCGDVDMKFRDHVGVEILSALFGTLHPGFY
                     RSRRESFTYERRPQSQAYIPWDQGDFYYMGAFFGGSVVEVHHLTKACHQAMVEDQDNG
                     IEAVWHDESHLNKYLLYHKPTKVLSPEYMWDQQLLGWPSIMKKLRYVAVPKNHQAIRN
                     "
     exon            109..178
                     /gene="Abo2"
                     /gene_synonym="NAGAT 2"
                     /inference="alignment:Splign:2.1.0"
     exon            179..235
                     /gene="Abo2"
                     /gene_synonym="NAGAT 2"
                     /inference="alignment:Splign:2.1.0"
     exon            236..271
                     /gene="Abo2"
                     /gene_synonym="NAGAT 2"
                     /inference="alignment:Splign:2.1.0"
     exon            272..406
                     /gene="Abo2"
                     /gene_synonym="NAGAT 2"
                     /inference="alignment:Splign:2.1.0"
     exon            407..1580
                     /gene="Abo2"
                     /gene_synonym="NAGAT 2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctccgggtgc cggagggtct gtgttcctgg gtgctattcc tccctgcctg tatccttcgg
       61 gcattgaact tggatgctgc agcagagcaa tgaaggatct gcggttggga agactgaaat
      121 gctactccct tcatcttgga atccttcccc tcacggtgct cgtcttagtc ttcttttgct
      181 tcgtgtgcct gagtctcaga agccaggaat gggggcaccc aggagctgtg aataggaagg
      241 cctatcccca gccaagggta ctgacaccca ctaggacaga tgttcttgtc ctgactcctt
      301 ggctggctcc catcatctgg gaggggacct tcaacattga catactgaat gagcagttca
      361 ggcttcggaa caccacaatc ggactaactg tgtttgccat caaaaagtat gtggtgttcc
      421 tgaagctctt cctggagacg gcagagcagc acttcatggt gggacataag gtcatctact
      481 atgtcttcac tgaccggcca gctgatgtcc cacaggtgcc cctgggtgca ggacggcggc
      541 tggtggtgct agctgtgcgc aactacaccc gctggcagga cgtgtccatg cacaggatgg
      601 agataatcag ccacttctca gagcagcgct tttggcatga ggtggactac ctggtgtgtg
      661 gagatgtgga catgaagttc agggaccacg tgggtgtgga gattctctca gcgctctttg
      721 gcaccctgca tcctggcttt taccgtagcc gacgagagtc ctttacctat gagcgccggc
      781 cacagtccca ggcctacatc ccctgggacc agggtgactt ttactatatg ggagccttct
      841 ttggggggtc agtggtggag gtgcaccatc tcaccaaggc ctgccaccag gctatggtgg
      901 aggaccagga caatggcatt gaggccgtgt ggcatgacga gagccatctg aacaagtacc
      961 tgctatacca taagccgaca aaggtgctgt ccccagagta catgtgggac cagcagctgc
     1021 tgggctggcc ctccatcatg aagaagctga gatatgtggc cgtgcccaag aaccatcagg
     1081 cgatcaggaa ctgatagctg aatccctgtt ggagaggcca ggccatagcc aggggcactc
     1141 cagcctgtgc tggaactgaa aagatttgag ggacaattgt caccctctat cccacctcag
     1201 agtccagcag gcccagtatc acttgggtta ccacacactt gagtcctgga gtggcaacca
     1261 tcttcatctc cactatgtgt ccctgagctc cttgcattga gtggcatggt atatggaatc
     1321 ttcagaacat ggagagactc tgttacatag ttaactgagg gctggtgcat cctccctcgg
     1381 gcttagtcct tcctcttcag ggaggcttga cagagggccc gtgcccatag gaacaggcag
     1441 gaaggcaggg agagtcagcc tgcagtccac agaggtgctt atctaccatt cagctcattc
     1501 ggggcagatc accgatcatt tttggtttat ttgggaatag gtatctatca attcctggga
     1561 ataaatgcat ttctaggtga
//
