LOCUS       NM_001177695            2685 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Rattus norvegicus actin binding LIM protein family, member 2
            (Ablim2), transcript variant 1, mRNA.
ACCESSION   NM_001177695
VERSION     NM_001177695.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2685)
  AUTHORS   Barrientos,T., Frank,D., Kuwahara,K., Bezprozvannaya,S.,
            Pipes,G.C., Bassel-Duby,R., Richardson,J.A., Katus,H.A., Olson,E.N.
            and Frey,N.
  TITLE     Two novel members of the ABLIM protein family, ABLIM-2 and -3,
            associate with STARS and directly bind F-actin
  JOURNAL   J Biol Chem 282 (11), 8393-8403 (2007)
   PUBMED   17194709
REFERENCE   2  (bases 1 to 2685)
  AUTHORS   Klimov,E., Rud'ko,O., Rakhmanaliev,E. and Sulimova,G.
  TITLE     Genomic organisation and tissue specific expression of ABLIM2 gene
            in human, mouse and rat
  JOURNAL   Biochim Biophys Acta 1730 (1), 1-9 (2005)
   PUBMED   16005990
  REMARK    GeneRIF: The highest expression of both isoforms was observed in
            rat brain and eye and in mouse embryos. ABLIM2 protein was
            necessary for the normal functioning of neurons.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ703892.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ703892.2 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2685
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..2685
                     /gene="Ablim2"
                     /note="actin binding LIM protein family, member 2"
                     /db_xref="GeneID:360958"
                     /db_xref="RGD:1303094"
     exon            1..168
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..1997
                     /gene="Ablim2"
                     /note="isoform a is encoded by transcript variant 1;
                     abLIM-2; actin-binding LIM protein 2"
                     /codon_start=1
                     /product="actin-binding LIM protein 2 isoform a"
                     /protein_id="NP_001171166.1"
                     /db_xref="GeneID:360958"
                     /db_xref="RGD:1303094"
                     /translation="MSAVSQPQAAHAPLEKPASTAILCNTCGNVCKGEVLRVQNKHFH
                     IRCFVCKACGCDLAEGGFFVRQGEHICTRDYQRLYGTRCFSCDCFIEGEVVSALGKTY
                     HPDCFVCAVCRLPFPPGDRVTFNGKDCMCQKCSPPTLVGNSAHVAQGLRSCGGCGLEI
                     KNGQALVALDKHWHLGCFKCKTCGKLLNAEYISKDGLPYCEADYHTKFGIRCDGCEKY
                     ITGRVLEAGEKHYHPSCALCVRCGQMFSEGEEMYLQGSSIWHPACRQAARTEDKSKET
                     RTSSESIVSVPASSTSGSPSRVIYAKLGDEILDYRDLAALPKNKAIYNIDRPDMISYS
                     PYISHSAVGDRQSYGEGDQDDRSYKQCRTSSPSSAGSVSLGHYTPTSRSPQHYSRPGS
                     ESGRSTPSLSVHSDSRPPSSTYQQAPRHFHVPDTGVKDNIYRKPPIYKQHAARRLDVE
                     DSSFDQDSRKKTTWLLLKGDADTRTNSPDLDSQSLSLSSGADQEPLQRMPGDSLYSRF
                     PYSKPDTLPGPRKDGLDLRNANLAPCGADPDASWGTREYKIYPYDSLIVTNRIRVKLP
                     KDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF"
     exon            169..312
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            313..496
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            497..612
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            613..739
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            740..833
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            834..921
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            922..980
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1058
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1208
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1329
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..1431
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1485
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1486..1538
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1677
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1739
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1740..1794
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..1802
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1803..1883
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
     exon            1884..2685
                     /gene="Ablim2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggagccccg atctgcggtg gctctgcggg cagcgggtac tgtgtgcgcc gagccgctgg
       61 cctcaagcgt gctgaggatc gtgccagcgc cgcacctgcc ggcccagtcc tcgggctgtc
      121 gcagcacggg gaccacccta ctgggagctg ccgctgacat gagtgcagtg tcgcagcccc
      181 aggctgctca tgccccactg gagaagccgg ccagcactgc gatcctgtgt aatacctgtg
      241 ggaatgtgtg caagggagag gtgctgcggg tgcagaacaa gcacttccac attaggtgct
      301 ttgtgtgcaa agcatgcggc tgtgacctgg ctgagggtgg cttcttcgtg aggcagggtg
      361 agcacatttg cacacgtgac taccagcggc tctatgggac tcgctgcttc agctgtgact
      421 gcttcattga aggggaagtg gtgtcagcgc ttgggaagac ctaccaccct gactgcttcg
      481 tatgcgctgt ctgcaggctg ccttttcctc ctggggaccg tgtgaccttc aatgggaagg
      541 attgtatgtg ccagaagtgt tctccaccca cattggtggg caacagtgcc catgtggccc
      601 agggcctccg gagttgtggg ggctgtggct tagaaatcaa gaatggccag gcactggtgg
      661 ctttggacaa gcactggcac ctgggatgct tcaagtgcaa gacttgtggg aaactcctca
      721 atgcagagta catcagcaag gatgggctgc cctactgtga ggctgattat cacaccaagt
      781 ttggcatccg ctgcgatggc tgtgagaagt acatcactgg tcgggtgctg gaggctggag
      841 agaagcacta ccacccttca tgtgcgctat gcgtcaggtg cggccagatg ttctcagagg
      901 gcgaggagat gtacctgcaa ggttcctcca tctggcatcc ggcatgtcgg caagcagcca
      961 ggactgaaga caagagcaag gaaaccagga cttcctcaga gagcattgtc tctgtgcctg
     1021 cctccagcac atcggggtcc ccaagccgtg tgatctatgc aaagcttggt gatgagatcc
     1081 tggactacag ggatttggct gctcttccca aaaacaaagc gatctacaac atcgaccgcc
     1141 ccgacatgat ctcctattcg ccctacatta gccactcggc tgtgggggac aggcagagct
     1201 atggtgaggg ggatcaggat gatcggtcct acaagcagtg caggacctcc agccccagct
     1261 ctgctggctc agtcagcctt gggcactaca ctccaacgtc acgatcaccc cagcactaca
     1321 gtcgtccagg cagcgaaagt ggccgtagca ctccaagtct ctcagtgcac tccgacagca
     1381 ggcctccttc ctctacctat cagcaggctc cgagacactt ccacgtccca gacactggcg
     1441 taaaagataa catctatagg aaacccccta tctacaaaca gcacgccgcc aggcgactgg
     1501 acgtggagga cagcagtttc gaccaggata gcaggaagaa gacaacgtgg ctgctcctca
     1561 agggagatgc agacaccaga actaactctc cggacttgga cagtcagtct ctgtccctca
     1621 gcagtggggc tgatcaagaa cctctccaaa ggatgccagg ggacagcctc tactcacgct
     1681 tcccttattc caaacccgac actctcccag gacccaggaa ggatggcctg gacctccgga
     1741 atgccaacct ggccccttgt ggagcagacc cggatgccag ctggggcacg cgagagtata
     1801 agatttatcc ctatgattcc ctcatcgtaa caaaccgaat tcgtgtgaaa ctgcccaaag
     1861 atgtagaccg gacacggctg gagagacacc tatcacctga agagttccaa gaagtgtttg
     1921 ggatgagcat cgaggagttt gaccgcctgg ccctgtggaa gaggaatgac ctcaagaaga
     1981 aagccttgct gttctgacag ctgccaacgt cttaccagga gcctgctggg ggcgtagggc
     2041 tgaaggaccc cactggcccc tccaaaatcc cctcctgcac cttgctctgc ttctccgtgt
     2101 cagtggggca ggcagggtgc ctgcaggagg cagggtgggg ccaggtcctg aggagcatcc
     2161 agcaggcatg gtcccttgtg tagcaaggat gctcctgcct gtagtttagg gccacgtgcc
     2221 agcttgaccc actccttccc gccacagctg ggcatcgggg cagtgttgca gctatcctag
     2281 gagacggggc agagcattca gccagcccag caccttccca gggcacctgg tgtgctcaca
     2341 cctgtgctag gcactggggc acagagtgtc tgggatgtga gtgaaaggct tgtcagtggc
     2401 agaccctgac acagtagtaa tggtaagtgc aagactcctc agtgcacgag gaggcatcgg
     2461 gcagactggc aggctgaggc aggggagcca ggccagtgtc tgagaggcag tggggctgtg
     2521 tttttcgcag ttattgtgat ggatcttttc tggggaatga atgtcgacct gacagggtgc
     2581 cccccactag tgctgtgcat ttgtattgtg cccttcttcc ggatcacccc cttagttgcc
     2641 taaatgatat ctttcaagtt acacagaagt ttttatttta ttaaa
//
